Items where Subject is "F165 Biomolecular Chemistry"

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Ab-initio computation Adsorption Adsorption geometries Animal Biotechnology Anti-tumor activities Antibody labelling Aptamers Binding affinity screening Bio-target identification Bio-targeting Biologics Biomimetic Synthesis Biomimetic synthesis Biomimicry Biomolecular identification Biosynthesis Biotarget identification Chemical characterisation Chemical proteomics Complex molecules Cytokines Deoxy sugars Diabetes Diels-Alder Drug discovery Drug labelling Drug off-targets Drug resistance Efficient schemes Enantiodivergent Enzymes Fatty acid synthase First passage time Fluorescent detection Fluorescent immuno-affinity label Fluorescent labels Fluorescent-labeled probes Force fields Force spectroscopy Free energy barrier Genetic algorithms Glycobiology Glycolipids High-throughput Immuno-affinity screening Inositol JCNotOpen JCOpen Lead discovery Malaria Malaria detection Maleimide reagents Mevalonate Mode-of-action Molecular Dynamics Simulation Molecular dynamics simulation Molecular dynamics simulations Molecular modeling Molecules NMR Natural product Natural products NotOAChecked Optimization Organic molecules Organic synthesis Orlistat Plasmodium Plasmodium falciparum Protein complex Protein domain motion QM/MM Quantum mechanics/molecular mechanics, Density functional theory Quantum theory, Adsorption energies Raman Spectroscopy Recombinant protein SNAP-tag technology Single molecule Structure-Activity Relationship Tetraols Total synthesis Total synthesis studies Transgenic animals Verapamil Wittig synthesis alkyl chain anti-tumour agents antiparasitic agents benzenoids bioassay bioassays bioimaging cell death chemical proteomics chloroquine click chemistry commercialisation conformations cyclization dimerization diradicals drug discovery drug labelling drug resistance dynamics enediynes fluorescent-labelled chloroquine fluorescent-tagged drug probes gold nanoparticles hyperpolarisation larvicidal malaria modular assembly monochlorination mosquito orlistat parasitology phenotypic screening ploylysine polyproline prion programmed cell death protein corona proteomics sulphur trypanosomiasis unfolded proteins
Number of items at this level: 155.

Ab-initio computation

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Adsorption

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Adsorption geometries

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Animal Biotechnology

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Anti-tumor activities

Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Antibody labelling

Song, Hong Y., Ngai, Mun H., Song, Zhen Y., MacAry, Paul A., Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520

Aptamers

Aubin-Tam, Marie-Eve, Appleyard, David C., Ferrari, Enrico, Garbin, Valeria, Fadiran, Oluwatimilehin O., Kunkel, Jacquelyn and Lang, Matthew J. (2011) Adhesion through single peptide aptamers. The Journal of Physical Chemistry A, 115 (16). pp. 3657-3664. ISSN 1089-5639

Binding affinity screening

Rodríguez, Abimael D., Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

Bio-target identification

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Bio-targeting

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Biologics

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Biomimetic Synthesis

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Biomimetic synthesis

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Biomimicry

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin, Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

Biomolecular identification

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Biosynthesis

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Biotarget identification

Rodríguez, Abimael D., Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

Chemical characterisation

Lear, Martin J., Simon, Oliver, Foley, Timothy L., Burkart, Michael D., Baiga, Thomas J., Noel, Joseph P., DiPasquale, Antonio G., Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Chemical proteomics

Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.

Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Complex molecules

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Cytokines

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Deoxy sugars

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Diabetes

Herbert, T. P., Kilhams, G. R., Batty, I. H. and Proud, C. G. (2000) Distinct signalling pathways mediate insulin and phorbol ester- stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells. Journal of Biological Chemistry, 275 (15). pp. 11249-11256. ISSN 0021-9258

Wicksteed, B., Herbert, T. P., Alarcon, C., Lingohr, M. K., Moss, L. G. and Rhodes, C. J. (2001) Cooperativity between the preproinsulin mRNA untranslated regions Is necessary for glucose-stimulated translation. Journal of Biological Chemistry, 276 (25). pp. 22553-22558. ISSN 0021-9258

Diels-Alder

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Drug discovery

Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain.

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Drug labelling

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Tejasvi, Amrita, Lear, Martin and Tan, Kevin (2012) Enhancing malaria research. Project Report. CyberMedia.

Drug off-targets

Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Drug resistance

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Tan, Kevin and Lear, Martin (2010) Scientists tag malaria superbugs. Singapore Press Holdings.

Tejasvi, Amrita, Lear, Martin and Tan, Kevin (2012) Enhancing malaria research. Project Report. CyberMedia.

Efficient schemes

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Enantiodivergent

Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

Enzymes

Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896

Fatty acid synthase

Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

First passage time

Roccatano, Danilo and Steven, Hayward (2019) Free Energy Profile of Domain Movement in Ligand-Free Citrate Synthase. The Journal of Physical Chemistry B, 123 (9). pp. 1998-2004. ISSN 1520-6106

Fluorescent detection

Tejasvi, Amrita, Lear, Martin and Tan, Kevin (2012) Enhancing malaria research. Project Report. CyberMedia.

Fluorescent immuno-affinity label

Rodríguez, Abimael D., Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

Fluorescent labels

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Fluorescent-labeled probes

Song, Hong Y., Ngai, Mun H., Song, Zhen Y., MacAry, Paul A., Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520

Force fields

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Force spectroscopy

Aubin-Tam, Marie-Eve, Appleyard, David C., Ferrari, Enrico, Garbin, Valeria, Fadiran, Oluwatimilehin O., Kunkel, Jacquelyn and Lang, Matthew J. (2011) Adhesion through single peptide aptamers. The Journal of Physical Chemistry A, 115 (16). pp. 3657-3664. ISSN 1089-5639

Free energy barrier

Roccatano, Danilo and Steven, Hayward (2019) Free Energy Profile of Domain Movement in Ligand-Free Citrate Synthase. The Journal of Physical Chemistry B, 123 (9). pp. 1998-2004. ISSN 1520-6106

Genetic algorithms

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Glycobiology

Lear, Martin, Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

Glycolipids

Lear, Martin, Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

High-throughput

Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322

Immuno-affinity screening

Lear, Martin J., Simon, Oliver, Foley, Timothy L., Burkart, Michael D., Baiga, Thomas J., Noel, Joseph P., DiPasquale, Antonio G., Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Inositol

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

JCNotOpen

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Roccatano, Danilo (2015) Structure, dynamics, and function of the monooxygenase P450 BM-3: insights from computer simulations studies. Journal of Physics: Condensed matter : an Institute of Physics journal, 27 (27). p. 273102. ISSN 0953-8984

JCOpen

Loh, Cheryl C. Y., Suwanarusk, Rossarin, Lee, Yan Quan, Chan, Kitti W. K., Choy, Kit-Ying, Rénia, Laurent, Russell, Bruce, Lear, Martin J., Nosten, François H., Tan, Kevin S. W., Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203

Lead discovery

Lear, Martin J., Simon, Oliver, Foley, Timothy L., Burkart, Michael D., Baiga, Thomas J., Noel, Joseph P., DiPasquale, Antonio G., Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Malaria

Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

Tan, Kevin and Lear, Martin (2010) Scientists tag malaria superbugs. Singapore Press Holdings.

Tejasvi, Amrita, Lear, Martin and Tan, Kevin (2012) Enhancing malaria research. Project Report. CyberMedia.

Malaria detection

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Maleimide reagents

Song, Hong Y., Ngai, Mun H., Song, Zhen Y., MacAry, Paul A., Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520

Mevalonate

Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

Mode-of-action

Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.

Molecular Dynamics Simulation

Roccatano, Danilo (2015) Structure, dynamics, and function of the monooxygenase P450 BM-3: insights from computer simulations studies. Journal of Physics: Condensed matter : an Institute of Physics journal, 27 (27). p. 273102. ISSN 0953-8984

Molecular dynamics simulation

Verma, Rajni, Schwaneberg, Ulrich and Roccatano, Danilo (2013) Conformational dynamics of the FMN-binding reductase domain of monooxygenase P450BM-3. Journal of Chemical Theory and Computation, 9 (1). pp. 96-105. ISSN 1549-9618

Molecular dynamics simulations

Roccatano, Danilo and Steven, Hayward (2019) Free Energy Profile of Domain Movement in Ligand-Free Citrate Synthase. The Journal of Physical Chemistry B, 123 (9). pp. 1998-2004. ISSN 1520-6106

Molecular modeling

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Molecules

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

NMR

Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896

Natural product

Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Natural products

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Lear, Martin J., Simon, Oliver, Foley, Timothy L., Burkart, Michael D., Baiga, Thomas J., Noel, Joseph P., DiPasquale, Antonio G., Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Rodríguez, Abimael D., Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

NotOAChecked

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

Optimization

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Organic molecules

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Organic synthesis

Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896

Orlistat

Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Plasmodium

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Plasmodium falciparum

Ch'ng, J.-H., Kotturi, S. R., Chong, A. G.-L., Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

Protein complex

Verma, Rajni, Schwaneberg, Ulrich and Roccatano, Danilo (2013) Conformational dynamics of the FMN-binding reductase domain of monooxygenase P450BM-3. Journal of Chemical Theory and Computation, 9 (1). pp. 96-105. ISSN 1549-9618

Protein domain motion

Roccatano, Danilo and Steven, Hayward (2019) Free Energy Profile of Domain Movement in Ligand-Free Citrate Synthase. The Journal of Physical Chemistry B, 123 (9). pp. 1998-2004. ISSN 1520-6106

QM/MM

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Quantum mechanics/molecular mechanics, Density functional theory

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Quantum theory, Adsorption energies

Gao, David Z., Federici Canova, Filippo, Watkins, Matthew B. and Shluger, Alexander L. (2015) Efficient parametrization of complex molecule-surface force fields. Journal of Computational Chemistry, 36 (16). pp. 1187-1195. ISSN 0192-8651

Raman Spectroscopy

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Subramanian, Gomathy, Stylianou, Con, Phang, In Yee, Cool, Simon, Nurcombe, Victor, Lear, Martin, Gorelik, Sergey, Fernig, David and Hobley, Jonathan (2020) Raman mapping glucose metabolites during human mesenchymal stem cell adipogenesis. bioRxiv .

Recombinant protein

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

SNAP-tag technology

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

Single molecule

Aubin-Tam, Marie-Eve, Appleyard, David C., Ferrari, Enrico, Garbin, Valeria, Fadiran, Oluwatimilehin O., Kunkel, Jacquelyn and Lang, Matthew J. (2011) Adhesion through single peptide aptamers. The Journal of Physical Chemistry A, 115 (16). pp. 3657-3664. ISSN 1089-5639

Structure-Activity Relationship

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

Tetraols

Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

Total synthesis

Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Lear, Martin, Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.

Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Total synthesis studies

Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain.

Transgenic animals

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Verapamil

Ch'ng, J.-H., Kotturi, S. R., Chong, A. G.-L., Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

Wittig synthesis

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

alkyl chain

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

anti-tumour agents

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

antiparasitic agents

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

benzenoids

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

bioassay

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

bioassays

Loh, Cheryl C. Y., Suwanarusk, Rossarin, Lee, Yan Quan, Chan, Kitti W. K., Choy, Kit-Ying, Rénia, Laurent, Russell, Bruce, Lear, Martin J., Nosten, François H., Tan, Kevin S. W., Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203

bioimaging

Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896

cell death

Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322

chemical proteomics

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

chloroquine

Loh, Cheryl C. Y., Suwanarusk, Rossarin, Lee, Yan Quan, Chan, Kitti W. K., Choy, Kit-Ying, Rénia, Laurent, Russell, Bruce, Lear, Martin J., Nosten, François H., Tan, Kevin S. W., Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203

click chemistry

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

commercialisation

Loh, Cheryl C. Y., Suwanarusk, Rossarin, Lee, Yan Quan, Chan, Kitti W. K., Choy, Kit-Ying, Rénia, Laurent, Russell, Bruce, Lear, Martin J., Nosten, François H., Tan, Kevin S. W., Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203

conformations

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

cyclization

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

dimerization

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

diradicals

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

drug discovery

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

drug labelling

Loh, Cheryl C. Y., Suwanarusk, Rossarin, Lee, Yan Quan, Chan, Kitti W. K., Choy, Kit-Ying, Rénia, Laurent, Russell, Bruce, Lear, Martin J., Nosten, François H., Tan, Kevin S. W., Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203

drug resistance

Loh, Cheryl C. Y., Suwanarusk, Rossarin, Lee, Yan Quan, Chan, Kitti W. K., Choy, Kit-Ying, Rénia, Laurent, Russell, Bruce, Lear, Martin J., Nosten, François H., Tan, Kevin S. W., Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203

dynamics

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

enediynes

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

fluorescent-labelled chloroquine

Ch'ng, J.-H., Kotturi, S. R., Chong, A. G.-L., Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

Tan, Kevin and Lear, Martin (2010) Scientists tag malaria superbugs. Singapore Press Holdings.

fluorescent-tagged drug probes

Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322

gold nanoparticles

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

hyperpolarisation

Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896

larvicidal

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

malaria

Ch'ng, J.-H., Kotturi, S. R., Chong, A. G.-L., Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

modular assembly

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

monochlorination

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

mosquito

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

orlistat

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

parasitology

Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322

phenotypic screening

Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322

ploylysine

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

polyproline

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

prion

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

programmed cell death

Ch'ng, J.-H., Kotturi, S. R., Chong, A. G.-L., Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

protein corona

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

proteomics

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

sulphur

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

trypanosomiasis

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

unfolded proteins

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

This list was generated on Mon May 10 12:42:58 2021 BST.