![]() | Up a level |
Caserta, Giorgio, Pecqueur, Ludovic, Adamska-Venkatesh, Agnieszka, Papini, Cecilia, Roy, Souvik, Artero, Vincent, Atta, Mohamed, Reijerse, Edward, Lubitz, Wolfgang and Fontecave, Marc (2017) Structural and functional characterization of the hydrogenase-maturation HydF protein. Nature Chemical Biology, 13 (7). pp. 779-784. ISSN 1552-4450
Ch'ng, J.-H., Kotturi, S. R., Chong, A. G.-L., Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889
Ch'ng, Jun-Hong, Mok, Sachel, Bozdech, Zbynek, Lear, Martin James, Boudhar, Aicha, Russell, Bruce, Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322
Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896
Fiers, William D., Craighead, Mark and Singh, Ishwar (2017) Teixobactin and its analogues: a new hope in antibiotic discovery. ACS Infectious Diseases, 3 (10). pp. 688-690. ISSN 2373-8227
Freeman, Colin, Cheallaigh, Aisling Ni, Singh, Ishwar and Heaney, Frances (2015) Isoxazole linked oligonucleotide conjugates by on resin and previously clicked nitrile oxide alkyne cycloadditions. Collection of Czechoslovak Chemical Communications, 12 . p. 333. ISSN 0010-0765
Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039
Henry, Sarah L., Withers, Jamie M., Singh, Ishwar, Cooper, Jonathan M., Clark, Alasdair W., Burley, Glenn A. and Cogdell, Richard J. (2015) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic & Biomolecular Chemistry, 14 (4). pp. 1359-1362. ISSN 1477-0520
Hicks, Matthew R., Gill, Andrew C., Bath, Imanpreet K., Rullay, Atvinder K., Sylvester, Ian D., Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X
Kyne, S. H., Miles, J. A. L., Percy, J. M. and Singh, K. (2012) Executing and rationalizing the synthesis of a difluorinated analogue of a ring-expanded calystegine B2. Journal of Organic Chemistry, 77 (2). pp. 991-998. ISSN 0022-3263
Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.
Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.
Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain.
Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.
Lear, Martin, Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236
Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.
Lear, Martin J., Simon, Oliver, Foley, Timothy L., Burkart, Michael D., Baiga, Thomas J., Noel, Joseph P., DiPasquale, Antonio G., Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864
Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345
Parmar, Anish, Iyer, Abhishek, Vincent, Charlotte, Van Lysebetten, Dorien, Prior, Stephen H., Madder, Annemieke, Taylor, Edward J. and Singh, Ishwar (2016) Efficient total syntheses and biological activities of two teixobactin analogues. Chemical Communications, 52 (36). pp. 6060-6063. ISSN 1359-7345
Parve, Jaan, Kudryashova, Marina, Shalima, Tatsiana, Villo, Ly, Ferschel, Moonika, Niidu, Allan, Liblikas, Ilme, Reile, Indrek, Aav, Riina, Gathergood, Nicholas, Vares, Lauri, Pehk, Tõnis and Parve, Omar (2023) Stereoselective Synthesis of γ‐(Acyloxy)carboxylic Acids and γ‐Lactones Featuring the Switch of Stereopreference of Candida antarctica Lipase B in Sodium γ‐Hydroxycarboxylate Homologues. European Journal of Organic Chemistry, 26 (3). e202201329. ISSN 1434-193X
Parve, Jaan, Kudryašova, Marina, Shalima, Tatsiana, Villo, Ly, Liblikas, Ilme, Reile, Indrek, Pehk, Tõnis, Gathergood, Nicholas, Aav, Riina, Vares, Lauri and Parve, Omar (2021) Scalable Lipase-Catalyzed Synthesis of (R)-4-(Acyloxy)pentanoic Acids from Racemic γ-Valerolactone. ACS Sustainable Chemistry & Engineering, 9 (4). pp. 1494-1499. ISSN 2168-0485
Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039
Perinelli, Diego Romano, Campana, Mario, Singh, Ishwar, Vllasaliu, Driton, Doutch, James, Palmieri, Giovanni Filippo and Casettari, Luca (2019) PEGylation affects the self-assembling behaviour of amphiphilic octapeptides. International Journal of Pharmaceutics, 571 (118752).
Rodríguez, Abimael D., Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863
Roe, S., Gunaratnam, M., Spiteri, C., Sharma, Pallavi, Alharthy, R. D., Neidle, S. and Moses, J. E. (2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Organic and Biomolecular Chemistry, 13 . pp. 8500-8504. ISSN 1477-0520
Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728
Singh, Ishwar, Heaney, Frances, Batchelor, Caroline and Vyle, Joseph S. (2015) Metal free click chemistry on nucleosides and oligonucleotides. Collection of Czechoslovak Chemical Communications, 10 . p. 451. ISSN 0010-0765
Singh, Ishwar and Walden, Benjamin (2018) Simplified teixobactin analogues to target superbugs. Future Medicinal Chemistry, 10 (2). ISSN 1756-8919
Song, Hong Y., Ngai, Mun H., Song, Zhen Y., MacAry, Paul A., Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520
Uthandi, Sivakumar, Kaliyaperumal, Ashokkumar, Srinivasan, Naganandhini, Thangavelu, Kiruthika, Muniraj, Iniya Kumar, Zhan, Xinmin, Gathergood, Nicholas and Gupta, Vijai Kumar (2021) Microbial biodiesel production from lignocellulosic biomass: New insights and future challenges. Critical Reviews in Environmental Science and Technology . pp. 1-30. ISSN 1064-3389
Whitaker, Darren A., Munshi, Tasnim, Scowen, Ian J. and Edwards, Howell G.M. (2021) Development of a Surface-Enhanced Raman Spectroscopic Methodology to Detect Immobilized Organic Materials in Biogeological Contexts. Astrobiology, 21 (9). pp. 1089-1098. ISSN 1531-1074
Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851
Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863
Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539