1

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

1,4-Dithiane-2,5-diol, Heterocycles, Thiophene, Michael/Aldol reactions

Francesco, Zamberlan, Anna, Fantinati and Claudio, Trapella (2018) 1,4‐Dithiane‐2,5‐diol: An Attractive Platform for the Synthesis of Sulfur Containing Functionalized Heterocycles. European Journal of Organic Chemistry, 2018 (25). pp. 3248-3264. ISSN 1434-193X

3-dipolar cycloaddition

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

Anitmalarial agents

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Anitproliferative activity

Brunton, V. G., Lear, M., Robins, D. J., Williamson, S. and Workman, P. (1994) Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties. Anti-Cancer Drug Design, 9 (4). pp. 291-309. ISSN 0266-9536

Anti-cancer

Scott, Fraser J., Puig-Sellart, Mireia, Khalaf, Abedawn I., Henderson, Catherine J., Westrop, Gareth, Watson, David G., Carter, Katharine, Grant, M. Helen and Suckling, Colin J. (2016) An evaluation of Minor Groove Binders as anti-lung cancer therapeutics. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

Anticancer

Munshi, Tasnim, Scowen, Ian, Abdull Manap, Mohd Rashidi, Ismail, Ahmad Zaidi, Ahmad, Haslina, Abdullah, Maryam Aisyah, Mohd Faudzi, Siti Munirah and Azamudin, Nurin Syahmimi (2018) Pyrrole-chalcone analogues as DNA binding agents. In: Industrial Chemistry Seminar XXI, 10 May 2018, Selangor, Malaysia.

Anticancer activity

Abd El-Karim, Somaia S., Syam, Yasmin M., El Kerdawy, Ahmed M. and Abdel-Mohsen, Heba T. (2024) Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents. Bioorganic Chemistry, 142 . p. 106920. ISSN 0045-2068

Antimalarial drug

Scott, Fraser J., Khalaf, Abedawn I., Duffy, Sandra, Avery, Vicky M. and Suckling, Colin J. (2016) Selective anti-malarial minor groove binders. Bioorganic & Medicinal Chemistry Letters, 26 (14). pp. 3326-3329. ISSN 0960-894X

Antiproliferative activity

Brunton, V. G., Lear, M., McKeown, P., Robins, D. J. and Workman, P. (1996) Synthesis and antiproliferative activity of tyrphostins containing quinoline moieties. Anti-Cancer Drug Design, 11 (6). pp. 463-483. ISSN 0266-9536

Antitumoral

Vasconcelos, Andreanne G., Barros, Ana Luisa A. N., Cabral, Wanessa F., Moreira, Daniel C., da Silva, Ingrid Gracielle M., Silva-Carvalho, Amandda É., de Almeida, Miguel P., Albuquerque, Lucas F. F., dos Santos, Raimunda C., S. Brito, Ana Karolinne, Saldanha-Araújo, Felipe, Arcanjo, Daniel D. R., C. Martins, Maria do Carmo, dos S. Borges, Tatiana K., Báo, Sônia N., Plácido, Alexandra, Eaton, Peter, Kuckelhaus, Selma A. S. and Leite, José Roberto S. A. (2021) Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells. Cancer Nanotechnology, 12 (1). ISSN 1868-6958

Artificial antibodies

Gruber, Tobias (2018) Synthetic receptors for the recognition and discrimination of post-translationally methylated lysines. ChemBioChem, 19 (22). pp. 2324-2340. ISSN 1439-4227

Binding Assay

Munshi, Tasnim, Scowen, Ian, Abdull Manap, Mohd Rashidi, Ismail, Ahmad Zaidi, Ahmad, Haslina, Abdullah, Maryam Aisyah, Mohd Faudzi, Siti Munirah and Azamudin, Nurin Syahmimi (2018) Pyrrole-chalcone analogues as DNA binding agents. In: Industrial Chemistry Seminar XXI, 10 May 2018, Selangor, Malaysia.

CAR

Brožová, Zuzana Rania, Dušek, Jan, Palša, Norbert, Maixnerová, Jana, Kamaraj, Rajamanikkam, Smutná, Lucie, Matouš, Petr, Braeuning, Albert, Pávek, Petr, Kuneš, Jiří, Gathergood, Nicholas, Špulák, Marcel, Pour, Milan and Carazo, Alejandro (2023) 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR). European Journal of Medicinal Chemistry, 259 . p. 115631. ISSN 0223-5234

Carotenoids

Vasconcelos, Andreanne G., Barros, Ana Luisa A. N., Cabral, Wanessa F., Moreira, Daniel C., da Silva, Ingrid Gracielle M., Silva-Carvalho, Amandda É., de Almeida, Miguel P., Albuquerque, Lucas F. F., dos Santos, Raimunda C., S. Brito, Ana Karolinne, Saldanha-Araújo, Felipe, Arcanjo, Daniel D. R., C. Martins, Maria do Carmo, dos S. Borges, Tatiana K., Báo, Sônia N., Plácido, Alexandra, Eaton, Peter, Kuckelhaus, Selma A. S. and Leite, José Roberto S. A. (2021) Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells. Cancer Nanotechnology, 12 (1). ISSN 1868-6958

Chitinophaga

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

Cyanamide

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

DNA minor groove binder

Scott, Fraser J., Khalaf, Abedawn I., Duffy, Sandra, Avery, Vicky M. and Suckling, Colin J. (2016) Selective anti-malarial minor groove binders. Bioorganic & Medicinal Chemistry Letters, 26 (14). pp. 3326-3329. ISSN 0960-894X

EGF receptor

Brunton, V. G., Kelland, L. R., Lear, M., Montgomary, G. J., Robertson, J. H., Robins, D. J., Queen, J. and Workman, P. (1996) Synthesis and biological evaluation of a series of tyrphostins containing nitrothiophene moieties as possible epidermal growth factor receptor tyrosine kinase inhibitors. Anti-Cancer Drug Design, 11 (4). pp. 265-295. ISSN 0266-9536

Epigenetics

Gruber, Tobias (2018) Synthetic receptors for the recognition and discrimination of post-translationally methylated lysines. ChemBioChem, 19 (22). pp. 2324-2340. ISSN 1439-4227

Falcitidin

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Gastrointestinal activity

de Sousa, Nayara Alves, Marani, Mariela M., Lopes, André Luís Fernandes, Silva, Emanuelle Morais, Barbosa, Eder Alves, Vasconcelos, Andreanne Gomes, Kuzniewski, Felipe T. B., Lustosa, Suellen Sousa, Gomes, Karina Pereira, Colugnati, Diego Basile, Rocha, Jefferson A., Santos, Lucianna Helene, Benquerer, Marcelo P., Quelemes, Patrick, Véras, Leiz, Moreira, Daniel C., Gadelha, Kalinne Kelly Lima, Magalhães, Pedro Jorge Caldas, Plácido, Alexandra, Eaton, Peter, Nicolau, Lucas, Medeiros, Jand Venes R. and Leite, José R. S. A. (2022) BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54 (5). pp. 733-747. ISSN 0939-4451

Gene activation

Brožová, Zuzana Rania, Dušek, Jan, Palša, Norbert, Maixnerová, Jana, Kamaraj, Rajamanikkam, Smutná, Lucie, Matouš, Petr, Braeuning, Albert, Pávek, Petr, Kuneš, Jiří, Gathergood, Nicholas, Špulák, Marcel, Pour, Milan and Carazo, Alejandro (2023) 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR). European Journal of Medicinal Chemistry, 259 . p. 115631. ISSN 0223-5234

Guava fruit

Vasconcelos, Andreanne G., Barros, Ana Luisa A. N., Cabral, Wanessa F., Moreira, Daniel C., da Silva, Ingrid Gracielle M., Silva-Carvalho, Amandda É., de Almeida, Miguel P., Albuquerque, Lucas F. F., dos Santos, Raimunda C., S. Brito, Ana Karolinne, Saldanha-Araújo, Felipe, Arcanjo, Daniel D. R., C. Martins, Maria do Carmo, dos S. Borges, Tatiana K., Báo, Sônia N., Plácido, Alexandra, Eaton, Peter, Kuckelhaus, Selma A. S. and Leite, José Roberto S. A. (2021) Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells. Cancer Nanotechnology, 12 (1). ISSN 1868-6958

JCNotOpen

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Scott, Fraser J., Khalaf, Abedawn I., Duffy, Sandra, Avery, Vicky M. and Suckling, Colin J. (2016) Selective anti-malarial minor groove binders. Bioorganic & Medicinal Chemistry Letters, 26 (14). pp. 3326-3329. ISSN 0960-894X

Scott, Fraser J., Puig-Sellart, Mireia, Khalaf, Abedawn I., Henderson, Catherine J., Westrop, Gareth, Watson, David G., Carter, Katharine, Grant, M. Helen and Suckling, Colin J. (2016) An evaluation of Minor Groove Binders as anti-lung cancer therapeutics. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

JCOpen

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

Knoevenagel reaction

Brunton, V. G., Lear, M., McKeown, P., Robins, D. J. and Workman, P. (1996) Synthesis and antiproliferative activity of tyrphostins containing quinoline moieties. Anti-Cancer Drug Design, 11 (6). pp. 463-483. ISSN 0266-9536

Brunton, V. G., Lear, M., Robins, D. J., Williamson, S. and Workman, P. (1994) Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties. Anti-Cancer Drug Design, 9 (4). pp. 291-309. ISSN 0266-9536

Lactam

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) The missing link in the homologous series of lactams: the X-ray structure of valerolactam. Crys. Growth Des., 18 (12). pp. 7248-7253. ISSN 1528-7483

Lactam antibiotic

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) The missing link in the homologous series of lactams: the X-ray structure of valerolactam. Crys. Growth Des., 18 (12). pp. 7248-7253. ISSN 1528-7483

Lung cancer

Scott, Fraser J., Puig-Sellart, Mireia, Khalaf, Abedawn I., Henderson, Catherine J., Westrop, Gareth, Watson, David G., Carter, Katharine, Grant, M. Helen and Suckling, Colin J. (2016) An evaluation of Minor Groove Binders as anti-lung cancer therapeutics. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

Lysine methylation

Gruber, Tobias (2018) Synthetic receptors for the recognition and discrimination of post-translationally methylated lysines. ChemBioChem, 19 (22). pp. 2324-2340. ISSN 1439-4227

MRSA

Singh, Ishwar and Walden, Benjamin (2018) Simplified teixobactin analogues to target superbugs. Future Medicinal Chemistry, 10 (2). ISSN 1756-8919

Metabolism

Brožová, Zuzana Rania, Dušek, Jan, Palša, Norbert, Maixnerová, Jana, Kamaraj, Rajamanikkam, Smutná, Lucie, Matouš, Petr, Braeuning, Albert, Pávek, Petr, Kuneš, Jiří, Gathergood, Nicholas, Špulák, Marcel, Pour, Milan and Carazo, Alejandro (2023) 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR). European Journal of Medicinal Chemistry, 259 . p. 115631. ISSN 0223-5234

Minor Groove Binders

Scott, Fraser J., Puig-Sellart, Mireia, Khalaf, Abedawn I., Henderson, Catherine J., Westrop, Gareth, Watson, David G., Carter, Katharine, Grant, M. Helen and Suckling, Colin J. (2016) An evaluation of Minor Groove Binders as anti-lung cancer therapeutics. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

Molecular Conformation

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma-lactam from a simple caprolactam derivative. New Journal of Chemistry, 41 . pp. 9984-9989. ISSN 1144-0546

Molecular structure

Munshi, Tasnim, Scowen, Ian, Abdull Manap, Mohd Rashidi, Ismail, Ahmad Zaidi, Ahmad, Haslina, Abdullah, Maryam Aisyah, Mohd Faudzi, Siti Munirah and Azamudin, Nurin Syahmimi (2018) Pyrrole-chalcone analogues as DNA binding agents. In: Industrial Chemistry Seminar XXI, 10 May 2018, Selangor, Malaysia.

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) The missing link in the homologous series of lactams: the X-ray structure of valerolactam. Crys. Growth Des., 18 (12). pp. 7248-7253. ISSN 1528-7483

Multi-kinase inhibitors

Abd El-Karim, Somaia S., Syam, Yasmin M., El Kerdawy, Ahmed M. and Abdel-Mohsen, Heba T. (2024) Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents. Bioorganic Chemistry, 142 . p. 106920. ISSN 0045-2068

NMR Spectroscopy

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma lactam from a simple caprolactam derivative. In: 20th European Symposium on Organic Chemistry, 2-6 July 2017, Cologne, Germany.

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma-lactam from a simple caprolactam derivative. New Journal of Chemistry, 41 . pp. 9984-9989. ISSN 1144-0546

Nanomedicine

Vasconcelos, Andreanne G., Barros, Ana Luisa A. N., Cabral, Wanessa F., Moreira, Daniel C., da Silva, Ingrid Gracielle M., Silva-Carvalho, Amandda É., de Almeida, Miguel P., Albuquerque, Lucas F. F., dos Santos, Raimunda C., S. Brito, Ana Karolinne, Saldanha-Araújo, Felipe, Arcanjo, Daniel D. R., C. Martins, Maria do Carmo, dos S. Borges, Tatiana K., Báo, Sônia N., Plácido, Alexandra, Eaton, Peter, Kuckelhaus, Selma A. S. and Leite, José Roberto S. A. (2021) Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells. Cancer Nanotechnology, 12 (1). ISSN 1868-6958

Nanomedicines

Ferrari, Enrico and Soloviev, Mikhail, eds. (2020) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, 2118 . Springer. ISBN 978-1-07-160318-5

Nanoparticle characterisation

Ferrari, Enrico and Soloviev, Mikhail, eds. (2020) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, 2118 . Springer. ISBN 978-1-07-160318-5

Nanoparticles

Ferrari, Enrico and Soloviev, Mikhail, eds. (2020) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, 2118 . Springer. ISBN 978-1-07-160318-5

Natural product

Gruber, Tobias (2017) Supramolecular receptors for the recognition and discrimination of post-translationally methylated lysines (PT2). In: 25th GP2A Medicinal Chemistry Conference, 31 Aug - 1 Sep 2017, Liverpool John Moores University.

Natural products

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Neuromedin B

de Sousa, Nayara Alves, Marani, Mariela M., Lopes, André Luís Fernandes, Silva, Emanuelle Morais, Barbosa, Eder Alves, Vasconcelos, Andreanne Gomes, Kuzniewski, Felipe T. B., Lustosa, Suellen Sousa, Gomes, Karina Pereira, Colugnati, Diego Basile, Rocha, Jefferson A., Santos, Lucianna Helene, Benquerer, Marcelo P., Quelemes, Patrick, Véras, Leiz, Moreira, Daniel C., Gadelha, Kalinne Kelly Lima, Magalhães, Pedro Jorge Caldas, Plácido, Alexandra, Eaton, Peter, Nicolau, Lucas, Medeiros, Jand Venes R. and Leite, José R. S. A. (2022) BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54 (5). pp. 733-747. ISSN 0939-4451

Nitrile Oxide

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

Nuclear receptors

Brožová, Zuzana Rania, Dušek, Jan, Palša, Norbert, Maixnerová, Jana, Kamaraj, Rajamanikkam, Smutná, Lucie, Matouš, Petr, Braeuning, Albert, Pávek, Petr, Kuneš, Jiří, Gathergood, Nicholas, Špulák, Marcel, Pour, Milan and Carazo, Alejandro (2023) 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR). European Journal of Medicinal Chemistry, 259 . p. 115631. ISSN 0223-5234

Oxadiazol-5-imine

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

Peptides. PEG

Perinelli, Diego Romano, Campana, Mario, Singh, Ishwar, Vllasaliu, Driton, Doutch, James, Palmieri, Giovanni Filippo and Casettari, Luca (2019) PEGylation affects the self-assembling behaviour of amphiphilic octapeptides. International Journal of Pharmaceutics, 571 (118752).

Pharmacokinetics

McLeod, H. L., Brunton, V. G., Eckardt, N., Lear, M. J., Robins, D. J., Workman, P. and Graham, M. A. (1996) In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022. British Journal of Cancer, 74 (11). pp. 1714-1718. ISSN 0007-0920

Plasmodium falciparum

Scott, Fraser J., Khalaf, Abedawn I., Duffy, Sandra, Avery, Vicky M. and Suckling, Colin J. (2016) Selective anti-malarial minor groove binders. Bioorganic & Medicinal Chemistry Letters, 26 (14). pp. 3326-3329. ISSN 0960-894X

Post-translational modification

Gruber, Tobias (2018) Synthetic receptors for the recognition and discrimination of post-translationally methylated lysines. ChemBioChem, 19 (22). pp. 2324-2340. ISSN 1439-4227

Principal Component Analysis

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981

Protein tyrosine kinases

Brunton, V. G., Lear, M., McKeown, P., Robins, D. J. and Workman, P. (1996) Synthesis and antiproliferative activity of tyrphostins containing quinoline moieties. Anti-Cancer Drug Design, 11 (6). pp. 463-483. ISSN 0266-9536

Brunton, V. G., Lear, M., Robins, D. J., Williamson, S. and Workman, P. (1994) Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties. Anti-Cancer Drug Design, 9 (4). pp. 291-309. ISSN 0266-9536

Pyrrole-chalcones

Munshi, Tasnim, Scowen, Ian, Abdull Manap, Mohd Rashidi, Ismail, Ahmad Zaidi, Ahmad, Haslina, Abdullah, Maryam Aisyah, Mohd Faudzi, Siti Munirah and Azamudin, Nurin Syahmimi (2018) Pyrrole-chalcone analogues as DNA binding agents. In: Industrial Chemistry Seminar XXI, 10 May 2018, Selangor, Malaysia.

Quinazolines

Brožová, Zuzana Rania, Dušek, Jan, Palša, Norbert, Maixnerová, Jana, Kamaraj, Rajamanikkam, Smutná, Lucie, Matouš, Petr, Braeuning, Albert, Pávek, Petr, Kuneš, Jiří, Gathergood, Nicholas, Špulák, Marcel, Pour, Milan and Carazo, Alejandro (2023) 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR). European Journal of Medicinal Chemistry, 259 . p. 115631. ISSN 0223-5234

Quinazolinone N-acetohydrazide

Abd El-Karim, Somaia S., Syam, Yasmin M., El Kerdawy, Ahmed M. and Abdel-Mohsen, Heba T. (2024) Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents. Bioorganic Chemistry, 142 . p. 106920. ISSN 0045-2068

Self assembly

Perinelli, Diego Romano, Campana, Mario, Singh, Ishwar, Vllasaliu, Driton, Doutch, James, Palmieri, Giovanni Filippo and Casettari, Luca (2019) PEGylation affects the self-assembling behaviour of amphiphilic octapeptides. International Journal of Pharmaceutics, 571 (118752).

Self-emulsifying

Vasconcelos, Andreanne G., Barros, Ana Luisa A. N., Cabral, Wanessa F., Moreira, Daniel C., da Silva, Ingrid Gracielle M., Silva-Carvalho, Amandda É., de Almeida, Miguel P., Albuquerque, Lucas F. F., dos Santos, Raimunda C., S. Brito, Ana Karolinne, Saldanha-Araújo, Felipe, Arcanjo, Daniel D. R., C. Martins, Maria do Carmo, dos S. Borges, Tatiana K., Báo, Sônia N., Plácido, Alexandra, Eaton, Peter, Kuckelhaus, Selma A. S. and Leite, José Roberto S. A. (2021) Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells. Cancer Nanotechnology, 12 (1). ISSN 1868-6958

Synthetic receptors

Gruber, Tobias (2018) Synthetic receptors for the recognition and discrimination of post-translationally methylated lysines. ChemBioChem, 19 (22). pp. 2324-2340. ISSN 1439-4227

Teixobactins

Singh, Ishwar, Malkawi, Ruba, Iyer, Abhishek, Parmar, Anish, Lloyd, Daniel, Goh, E, Taylor, Edward, Sarmad, Sarir, Madder, A and Lakshminarayanan, R (2018) Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA). Pharmaceutics, 10 (4). p. 183. ISSN 1999-4923

Tetrapeptide

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Trifluormethyl

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Tyrophostins

Brunton, V. G., Lear, M., Robins, D. J., Williamson, S. and Workman, P. (1994) Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties. Anti-Cancer Drug Design, 9 (4). pp. 291-309. ISSN 0266-9536

Tyrosine kinase inhibitors

Brunton, V. G., Kelland, L. R., Lear, M., Montgomary, G. J., Robertson, J. H., Robins, D. J., Queen, J. and Workman, P. (1996) Synthesis and biological evaluation of a series of tyrphostins containing nitrothiophene moieties as possible epidermal growth factor receptor tyrosine kinase inhibitors. Anti-Cancer Drug Design, 11 (4). pp. 265-295. ISSN 0266-9536

Tyrphostins

Brunton, V. G., Lear, M., McKeown, P., Robins, D. J. and Workman, P. (1996) Synthesis and antiproliferative activity of tyrphostins containing quinoline moieties. Anti-Cancer Drug Design, 11 (6). pp. 463-483. ISSN 0266-9536

VRE

Singh, Ishwar and Walden, Benjamin (2018) Simplified teixobactin analogues to target superbugs. Future Medicinal Chemistry, 10 (2). ISSN 1756-8919

Valerolactam

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) The missing link in the homologous series of lactams: the X-ray structure of valerolactam. Crys. Growth Des., 18 (12). pp. 7248-7253. ISSN 1528-7483

Vibrational spectroscopy

Munshi, Tasnim, Scowen, Ian, Abdull Manap, Mohd Rashidi, Ismail, Ahmad Zaidi, Ahmad, Haslina, Abdullah, Maryam Aisyah, Mohd Faudzi, Siti Munirah and Azamudin, Nurin Syahmimi (2018) Pyrrole-chalcone analogues as DNA binding agents. In: Industrial Chemistry Seminar XXI, 10 May 2018, Selangor, Malaysia.

X-ray diffraction

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma lactam from a simple caprolactam derivative. In: 20th European Symposium on Organic Chemistry, 2-6 July 2017, Cologne, Germany.

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) The missing link in the homologous series of lactams: the X-ray structure of valerolactam. Crys. Growth Des., 18 (12). pp. 7248-7253. ISSN 1528-7483

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma-lactam from a simple caprolactam derivative. New Journal of Chemistry, 41 . pp. 9984-9989. ISSN 1144-0546

Xenobiotics

Brožová, Zuzana Rania, Dušek, Jan, Palša, Norbert, Maixnerová, Jana, Kamaraj, Rajamanikkam, Smutná, Lucie, Matouš, Petr, Braeuning, Albert, Pávek, Petr, Kuneš, Jiří, Gathergood, Nicholas, Špulák, Marcel, Pour, Milan and Carazo, Alejandro (2023) 2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR). European Journal of Medicinal Chemistry, 259 . p. 115631. ISSN 0223-5234

amphibian

de Sousa, Nayara Alves, Marani, Mariela M., Lopes, André Luís Fernandes, Silva, Emanuelle Morais, Barbosa, Eder Alves, Vasconcelos, Andreanne Gomes, Kuzniewski, Felipe T. B., Lustosa, Suellen Sousa, Gomes, Karina Pereira, Colugnati, Diego Basile, Rocha, Jefferson A., Santos, Lucianna Helene, Benquerer, Marcelo P., Quelemes, Patrick, Véras, Leiz, Moreira, Daniel C., Gadelha, Kalinne Kelly Lima, Magalhães, Pedro Jorge Caldas, Plácido, Alexandra, Eaton, Peter, Nicolau, Lucas, Medeiros, Jand Venes R. and Leite, José R. S. A. (2022) BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54 (5). pp. 733-747. ISSN 0939-4451

antibiotics

Singh, Ishwar, Malkawi, Ruba, Iyer, Abhishek, Parmar, Anish, Lloyd, Daniel, Goh, E, Taylor, Edward, Sarmad, Sarir, Madder, A and Lakshminarayanan, R (2018) Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA). Pharmaceutics, 10 (4). p. 183. ISSN 1999-4923

antibiotics•antimicrobial resistance•drug development•lipid II•MRSA•Mycobacterium tuberculosis •peptides•Teixobactin•VRE

Iyer, Abhishek, Madder, Annemieke and Singh, Ishwar (2019) Teixobactins: a new class of 21st century antibiotics to combat multi-drug resistant bacterial pathogens. Future Microbiology, 14 . pp. 457-460. ISSN 1746-0913

antimicrobials

Singh, Ishwar, Malkawi, Ruba, Iyer, Abhishek, Parmar, Anish, Lloyd, Daniel, Goh, E, Taylor, Edward, Sarmad, Sarir, Madder, A and Lakshminarayanan, R (2018) Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA). Pharmaceutics, 10 (4). p. 183. ISSN 1999-4923

antiparasitic agents

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

artificial receptor

Gruber, Tobias (2017) Synthetic receptors for the recognition and discrimination of epigenetically modified lysines. In: 25th Annual GP2A Medicinal Chemistry Conference, 31st August - 1st September 2017, Liverpool.

bioactive peptide

de Sousa, Nayara Alves, Marani, Mariela M., Lopes, André Luís Fernandes, Silva, Emanuelle Morais, Barbosa, Eder Alves, Vasconcelos, Andreanne Gomes, Kuzniewski, Felipe T. B., Lustosa, Suellen Sousa, Gomes, Karina Pereira, Colugnati, Diego Basile, Rocha, Jefferson A., Santos, Lucianna Helene, Benquerer, Marcelo P., Quelemes, Patrick, Véras, Leiz, Moreira, Daniel C., Gadelha, Kalinne Kelly Lima, Magalhães, Pedro Jorge Caldas, Plácido, Alexandra, Eaton, Peter, Nicolau, Lucas, Medeiros, Jand Venes R. and Leite, José R. S. A. (2022) BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54 (5). pp. 733-747. ISSN 0939-4451

calixarene

Gruber, Tobias (2017) Artificial receptors for the discrimination of epigenetically modified lysines. In: Dial-a-Molecule Annual Meeting 2017, 21 June 2017, Liverpool.

Gruber, Tobias (2018) From synthetic receptors to bridged caprolactams. In: Pharmazeutisches Kolloquium, 26th April 2018, Graz, Austria.

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Chemiedozententagung 2018, 5 -7 March 2018, Jena, Germany.

Gruber, Tobias (2017) Synthetic receptors for the recognition and discrimination of epigenetically modified lysines. In: 25th Annual GP2A Medicinal Chemistry Conference, 31st August - 1st September 2017, Liverpool.

caprolactam

Gruber, Tobias (2018) From synthetic receptors to bridged caprolactams. In: Pharmazeutisches Kolloquium, 26th April 2018, Graz, Austria.

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma lactam from a simple caprolactam derivative. In: 20th European Symposium on Organic Chemistry, 2-6 July 2017, Cologne, Germany.

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma-lactam from a simple caprolactam derivative. New Journal of Chemistry, 41 . pp. 9984-9989. ISSN 1144-0546

carbamazepine

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

chemical biology

Gruber, Tobias (2017) Artificial receptors for the discrimination of epigenetically modified lysines. In: Dial-a-Molecule Annual Meeting 2017, 21 June 2017, Liverpool.

digoxin

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981

drug design

Gruber, Tobias (2017) Supramolecular receptors for the recognition and discrimination of post-translationally methylated lysines (PT2). In: 25th GP2A Medicinal Chemistry Conference, 31 Aug - 1 Sep 2017, Liverpool John Moores University.

drug discovery

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

drug synthesis

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma-lactam from a simple caprolactam derivative. New Journal of Chemistry, 41 . pp. 9984-9989. ISSN 1144-0546

drugs of abuse

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

electrochemistry

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981

Gonzalez-Rodriguez, Jose, Sevilla, Jose Manuel, Pineda, Teresa, Blazquez, Manuel and Lopez, Maria del Mar (2020) A study on the electrooxidation of Vitamin B6 compounds on glassy carbon and polycrystalline gold electrodes. Journal of ElectroAnalytical Chemistry, 877 . p. 114525. ISSN 1572-6657

epigenetics

Gruber, Tobias (2017) Synthetic receptors for the recognition and discrimination of epigenetically modified lysines. In: 25th Annual GP2A Medicinal Chemistry Conference, 31st August - 1st September 2017, Liverpool.

falcipain

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

falcitidin

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

fluorescophane

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Chemiedozententagung 2018, 5 -7 March 2018, Jena, Germany.

forensic science

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981

forensic toxicology

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

gastric secretion

de Sousa, Nayara Alves, Marani, Mariela M., Lopes, André Luís Fernandes, Silva, Emanuelle Morais, Barbosa, Eder Alves, Vasconcelos, Andreanne Gomes, Kuzniewski, Felipe T. B., Lustosa, Suellen Sousa, Gomes, Karina Pereira, Colugnati, Diego Basile, Rocha, Jefferson A., Santos, Lucianna Helene, Benquerer, Marcelo P., Quelemes, Patrick, Véras, Leiz, Moreira, Daniel C., Gadelha, Kalinne Kelly Lima, Magalhães, Pedro Jorge Caldas, Plácido, Alexandra, Eaton, Peter, Nicolau, Lucas, Medeiros, Jand Venes R. and Leite, José R. S. A. (2022) BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54 (5). pp. 733-747. ISSN 0939-4451

gastrin releasing peptide

de Sousa, Nayara Alves, Marani, Mariela M., Lopes, André Luís Fernandes, Silva, Emanuelle Morais, Barbosa, Eder Alves, Vasconcelos, Andreanne Gomes, Kuzniewski, Felipe T. B., Lustosa, Suellen Sousa, Gomes, Karina Pereira, Colugnati, Diego Basile, Rocha, Jefferson A., Santos, Lucianna Helene, Benquerer, Marcelo P., Quelemes, Patrick, Véras, Leiz, Moreira, Daniel C., Gadelha, Kalinne Kelly Lima, Magalhães, Pedro Jorge Caldas, Plácido, Alexandra, Eaton, Peter, Nicolau, Lucas, Medeiros, Jand Venes R. and Leite, José R. S. A. (2022) BR-bombesin: a novel bombesin-related peptide from the skin secretion of the Chaco tree frog (Boana raniceps) with physiological gastric effects. Amino Acids, 54 (5). pp. 733-747. ISSN 0939-4451

glassy carbon electrode

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

Gonzalez-Rodriguez, Jose, Sevilla, Jose Manuel, Pineda, Teresa, Blazquez, Manuel and Lopez, Maria del Mar (2020) A study on the electrooxidation of Vitamin B6 compounds on glassy carbon and polycrystalline gold electrodes. Journal of ElectroAnalytical Chemistry, 877 . p. 114525. ISSN 1572-6657

heterocycles

Baricordi, Nikla, Benetti, Simonetta, Bertolasi, Valerio, De Risi, Carmela, Pollini, Gian P., Zamberlan, Francesco and Zanirato, Vinicio (2012) 1,4-Dithiane-2,5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes. Tetrahedron, 68 (1). pp. 208-213. ISSN 0040-4020

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

lactams

Gruber, Tobias (2018) From synthetic receptors to bridged caprolactams. In: Pharmazeutisches Kolloquium, 26th April 2018, Graz, Austria.

macrocycle

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Chemiedozententagung 2018, 5 -7 March 2018, Jena, Germany.

malaria

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

medicinal chemistry

Gruber, Tobias (2017) Supramolecular receptors for the recognition and discrimination of post-translationally methylated lysines (PT2). In: 25th GP2A Medicinal Chemistry Conference, 31 Aug - 1 Sep 2017, Liverpool John Moores University.

methyllysine

Gruber, Tobias (2017) Synthetic receptors for the recognition and discrimination of epigenetically modified lysines. In: 25th Annual GP2A Medicinal Chemistry Conference, 31st August - 1st September 2017, Liverpool.

methyllysines

Gruber, Tobias (2018) From synthetic receptors to bridged caprolactams. In: Pharmazeutisches Kolloquium, 26th April 2018, Graz, Austria.

microelectrodes

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

multivariate analysis

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981

myxobacteria

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

organic chemistry

Baricordi, Nikla, Benetti, Simonetta, Bertolasi, Valerio, De Risi, Carmela, Pollini, Gian P., Zamberlan, Francesco and Zanirato, Vinicio (2012) 1,4-Dithiane-2,5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes. Tetrahedron, 68 (1). pp. 208-213. ISSN 0040-4020

organic synthesis

Baricordi, Nikla, Benetti, Simonetta, Bertolasi, Valerio, De Risi, Carmela, Pollini, Gian P., Zamberlan, Francesco and Zanirato, Vinicio (2012) 1,4-Dithiane-2,5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes. Tetrahedron, 68 (1). pp. 208-213. ISSN 0040-4020

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma lactam from a simple caprolactam derivative. In: 20th European Symposium on Organic Chemistry, 2-6 July 2017, Cologne, Germany.

orlistat

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

peptide synthesis

Singh, Ishwar, Malkawi, Ruba, Iyer, Abhishek, Parmar, Anish, Lloyd, Daniel, Goh, E, Taylor, Edward, Sarmad, Sarir, Madder, A and Lakshminarayanan, R (2018) Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA). Pharmaceutics, 10 (4). p. 183. ISSN 1999-4923

polycrystalline gold electrode

Gonzalez-Rodriguez, Jose, Sevilla, Jose Manuel, Pineda, Teresa, Blazquez, Manuel and Lopez, Maria del Mar (2020) A study on the electrooxidation of Vitamin B6 compounds on glassy carbon and polycrystalline gold electrodes. Journal of ElectroAnalytical Chemistry, 877 . p. 114525. ISSN 1572-6657

prodrug

Gruber, Tobias (2017) Supramolecular receptors for the recognition and discrimination of post-translationally methylated lysines (PT2). In: 25th GP2A Medicinal Chemistry Conference, 31 Aug - 1 Sep 2017, Liverpool John Moores University.

proteomics

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

pyridoxine

Gonzalez-Rodriguez, Jose, Sevilla, Jose Manuel, Pineda, Teresa, Blazquez, Manuel and Lopez, Maria del Mar (2020) A study on the electrooxidation of Vitamin B6 compounds on glassy carbon and polycrystalline gold electrodes. Journal of ElectroAnalytical Chemistry, 877 . p. 114525. ISSN 1572-6657

solid electrodes

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981

structure-based

Gruber, Tobias (2017) Supramolecular receptors for the recognition and discrimination of post-translationally methylated lysines (PT2). In: 25th GP2A Medicinal Chemistry Conference, 31 Aug - 1 Sep 2017, Liverpool John Moores University.

sulfur

Baricordi, Nikla, Benetti, Simonetta, Bertolasi, Valerio, De Risi, Carmela, Pollini, Gian P., Zamberlan, Francesco and Zanirato, Vinicio (2012) 1,4-Dithiane-2,5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes. Tetrahedron, 68 (1). pp. 208-213. ISSN 0040-4020

supramolecular chemistry

Gruber, Tobias (2017) Artificial receptors for the discrimination of epigenetically modified lysines. In: Dial-a-Molecule Annual Meeting 2017, 21 June 2017, Liverpool.

Gruber, Tobias (2017) Synthetic receptors for the recognition and discrimination of epigenetically modified lysines. In: 25th Annual GP2A Medicinal Chemistry Conference, 31st August - 1st September 2017, Liverpool.

tetrapeptide

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

trypanosomiasis

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

tumour xenograft

McLeod, H. L., Brunton, V. G., Eckardt, N., Lear, M. J., Robins, D. J., Workman, P. and Graham, M. A. (1996) In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022. British Journal of Cancer, 74 (11). pp. 1714-1718. ISSN 0007-0920

tyrosine kinase inhibitor

McLeod, H. L., Brunton, V. G., Eckardt, N., Lear, M. J., Robins, D. J., Workman, P. and Graham, M. A. (1996) In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022. British Journal of Cancer, 74 (11). pp. 1714-1718. ISSN 0007-0920

tyrphostin

McLeod, H. L., Brunton, V. G., Eckardt, N., Lear, M. J., Robins, D. J., Workman, P. and Graham, M. A. (1996) In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022. British Journal of Cancer, 74 (11). pp. 1714-1718. ISSN 0007-0920

vitamin B6

Gonzalez-Rodriguez, Jose, Sevilla, Jose Manuel, Pineda, Teresa, Blazquez, Manuel and Lopez, Maria del Mar (2020) A study on the electrooxidation of Vitamin B6 compounds on glassy carbon and polycrystalline gold electrodes. Journal of ElectroAnalytical Chemistry, 877 . p. 114525. ISSN 1572-6657

voltammetry

Atkins, S., Sevilla, J. M., Blazquez, M., Pineda, T. and Gonzalez-Rodriguez, Jose (2010) Electrochemical behaviour of carbamazepine in acetonitrile and dimethylformamide using glassy carbon electrodes and microelectrodes. Electroanalysis, 22 (24). pp. 2961-2966. ISSN 1521-4109

Gonzalez-Rodriguez, Jose, Bellia, Gaetano, Corrall, Hannah, Baron, Mark and Croxton, Ruth (2017) An investigation of digoxin by cyclic voltammetry using gold and silver solid electrodes and chemometric analysis. International Journal of Electrochemical Science, 12 . pp. 3050-3062. ISSN 1452-3981