Items where Subject is "B200 Pharmacology, Toxicology and Pharmacy"

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(E) - capsaicin 1-methyl-4-phenylpyridinium 1H 2 amino 4 nitrophenol 2 propanol 31P 4 nitrophenol 5-IAI AEA AFM AIDS AMPA ATF4 ATP Absorption enhancement Accelerator mass spectrometry Acid condition Acid-base complexation reaction Acne Additive manufacturing Adolescent Adult Adverse drug reactions Age related macular degeneration Aged Aged, 80 and over Alkylation Alkylglycosides Alkynes Allium Allium cepa Allium sativum Alzheimer's Amino acid Ammonia Amphibian Amyloid Amyloidogenesis Anionic antimicrobial peptides Antibiosis Antibiotic resistance Anticancer Anticoagulants Antimicrobial Antimicrobial agent Antimicrobial peptide Antioxidants Anxiety Apoptosis Area Under Curve Article Artificial organs Aspergillus fumigatu Aspirin Azides BSO Bacteriocins Basement membrane Batch Cell Culture Techniques Beclometasone dipropionate Bespoke Beta cell Biocompatibility Bioconjugation} Biological Markers Biomarkers Biosynthesis Bisphosphonates Brain Brain Slices Breast cancer Bronchial alveolar lavage Butanols Byproducts CHO cells CHOP CNS COVID-19 CYP1A1 Caco-2 Caco-2 cells Calcium depletion Calu-3 Calu-3 cells Cancer Candida albicans Carbon Radioisotopes Carbon-Sulfur Lyases Cardiac Catalysis Cell adhesion Cell contraction Cell mechanic Cell monolayers Cell surface morphology Cell surface roughness Cell uptake Cells Cells adhesion Cellular stress response Cellular uptake Characterisation Charge transfer Chemical gas sensor Chemistry Chemistry, Pharmaceutical Chemotherapy Chitosan Chloroquine Cholesteryl esters Chromatography, Liquid Cinchona pubescens Click reaction Clinical trial Co-crystal Coagulopathy Complex I Complexes Computer simulation Control charts Cross-Over Studies Crystal engineering Crystal interfaces Crystal structure Crystallisation Crystallization Crystallography, X-Ray Crystals Cycloaddition D-mannitol D2 receptor D3 receptor DNA DNA Virus DNA methylation DNA-protein interactions Delta-9-tetrahydrocannabinol Depression Derivatisation Derivative Diabetes Diabetes mellitus Diaminopyrimidine antibiotic Disease Progression Dissolution Dissolution rates Dodecylmaltoside Dog Dose linearity Dose-Response Relationship, Drug Drug Design Drug Monitoring Drug Stability Drug Storage Drug delivery Drug development Drug products Drug products plants Dyes E-cigarette EM EPHX1 ER stress Elastic properties Elasticity Electron Microscopy Electron Transport Chain Electronic Clinical-Patient Dataset. Endocytosis Enterococcus faecium Enzymatic synthesis Enzymes Epilepsy Epipolythiodioxopiperazine Epithelial barrier Epithelial cells Epithelial models Epithelial permeability Escherichia coli Estradiol Eugenol Excipients Extracellular matrix protein FTIR Fanconi renotubular syndrome FcRn pathway Focal adhesions Folate ligands Food Microbiology Foodborne Diseases Forensic Science Fracture Fructose Funnel plots GABA Modulators GC-MS GCM GHB concentration GSH GSIS Gamma-hydroxybutyrate Gene delivery Gene therapy Glass Gliotoxin Glutamate receptors Glutathione Glycosides Good correlations Great Britain Guinea pig ileum H202 H460 HIV HU 210 Health related quality of life Heart Helicobacter pylori High-resolution imaging Human keratinocytes Humans Huntington Disease Huntington chorea Hydrocortisone Hydrogen bonds Hydrogen chloride Hydrogen peroxide Hydroxybutyrate IgG Image reconstruction Imaging systems Immumnoelectron microscopy Immunocytochemistry Immunofluorescence staining In situ crystallization Injection Injection port Injections, Intravenous Integrins Interfacial interaction Intra-arterial microdosing Ischaemia Ischemia Islet Islet transplantation Isotopes JCNotOpen JCOpen Keratinocytes Kidney Kinetics L-buthionine sulfoximine Lactose monoester Ligand density Linear elasticity Liposome Liposomes Liquid crystals Listeria Liver Lung MMSY2 MPP+ MPTP MRS Macromolecular permeability Magnetic field strength Malaysia Mammalia Marijuana Smoking Mass spectrometry Mechanics Medical applications Medicinal chemistr Membranolysis Mental health Metabolism Metal free porphyrin Metastable polymorphs Methane Microcrystalline test Microdose Microdosing Microspheres Middle Aged Mitochondria Molecular Structure Mucoadhesion Mucosal delivery Mucosal protein delivery Multicomponent crystals Multiplex Polymerase Chain Reaction N omega-nitro-L-arginine NMR NMR Spectroscopy NMR spectroscopy NOS NRPS Nanomedicines Nanoparticle transport Nanoparticles Nanotechnology Nanotoxicity Nasal 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Polymorphs, Powders, solvent Supersensitivity Supramolecular chemistry, Drug products, er 34122 Surface modification Surface plasmon excitation Surface plasmon resonance, Plasmons, vinculin, article Surfactants Suspensions Synaptosomal Synaptosomes Synchrotrons Synthesis TASTPM TBC TEER THC TRPV1 TSC2 Tablets Technology, Pharmaceutical Temperature Temperature measurement, Thermochromic polymeric films, Plastic films Tetradecylmaltoside Tight junction modulation Tight junctions Time Factors Tissue engineering Tissue engineering, Cells Tobacco Toxicity Toxicology Transcription Transepithelial electrical resistance Treatment Outcome Tridecylmaltoside Tumors Type 2 diabetes mellitus UPR Ultrasensitive drug analysis, Carbon, Animalia Unsaturated fatty acid Uptake inhibition Vaccine delivery Van de Graaff accelerators, Accelerator mass spectrometry Vanilloid Vanilloids Veterinary Antivirals Virology Water Watercress Wide-field, Cell adhesion Women X ray analysis X ray diffraction, 2-Propanol X ray powder diffraction X ray powder diffraction, Benzamide X-ray diffraction Xanthone Y-box protein abasic site absorption enhancers acetyl-L-carnitine acne acute liver failure adult adverse drug reactions airway dynamics alliin lyase alpha 1 adrenergic receptor blocking agent amenorrhea ammonia amyloid precursor protein anandamide anionic host defence peptides. antibiotics anticancer anticoagulation antidepressants antiestrogen anxiety disorder apoptosis aqueous solution area under the curve article asthenia ataxia atenolol bacteriocin beclometasone dipropionate benzodiazepines beta-adrenoceptors bioengineering biological medicines biosimilars bipolar I disorder bipolar disorder blood dyscrasia bmjconvert bmjdownload bmjindex brain brain slices brain stem budesonide cAMP caffeine cancer cannabinoid cannabis, adult capsazepine carbamazepine carbon 14 carbon tetrachloride case report celiprolol cell adhesion cell interaction cell surface cellular distribution cellular stress cerebral ischaemia cerebral ischemia chemical modification chemical phenomena chemical reaction chemical structure chemistry child care chitosan chlorimipramine cholesterol clarithromycin clinical article clinical trial clomipramine complex geometry complexexs computer simulation conference paper constipation controlled clinical trial controlled study cornea reflex cost effectiveness analysis cross linking crystal crystal structure crystallization crystallography culture technique curcumin curriculum cyclic-AMP cysteine cytochrome P450 3A4 data analysis data base databases dementia demography development diagnostic and therapeutic imaging diazepam differential scanning calorimetry digoxin diphenhydramine disease association disease course dopamine dopamine receptor dose calculation dose response dose time effect relation drowsiness drug drug absorption drug activity drug and gene delivery drug bioavailability drug blood level drug classification drug clearance drug cost drug delivery system drug derivative drug distribution drug effect drug efficacy drug eruption drug formulation drug half life drug impurity drug mechanism drug metabolism drug microdose drug monitoring drug penetration drug research drug retention drug safety drug solubility drug stability drug structure drug withdrawal dyspepsia eIF2? eNOS edema elderly care electron transport chain element enalapril endocannabinoid endothelial energy transfer enterocin enzymes erythrocyte disorder erythromycin excitotoxicity extracellular extrapyramidal symptom eye movement control factual fast GC-MS screening feline calicivirus female fentanyl fermentation fever fexofenadine flow rate fluconazole folic acid food food and drug administration forensic drug analysis fosdevirine free radicals garlic gene expression gene transcription general practice genetics genomic glibenclamide glioma glucose glutamate glutamate toxicity glutamic acid, article glycoprotein P glycosides griseofulvin growth inhibition zone gynecomastia hair loss half life time haloperidol health care cost health care financing health care utilization hearing loss hepatitis high performance liquid chromatography hirsutism hospitalization human human tissue hydration hydrocortisone, article hydrogen bond hydrogen peroxide hydrolysis hydrophilicity hydrophobicity hyperammonemia hypercholesterolemia hyperglycemia hyperprolactinemia hypertension hypertriglyceridemia hypothyroidism imaging system immobilized lipas immunocytochemistry immunofluorescence increased appetite influenza influenza vaccination insulin interview isobutanol kainate keratinocyte kinetics legal highs length of stay leukopenia liposome lipoxygenase inhibitor liquid chromatography liquid crystal listeriosis lithium liver clearance liver failure local formularies lorazepam losartan low- and middle-income countries lung cancer lyase mRNA mTOR mTORC1 mTORC2 male maleic acid manganese [III] tetrakis 4-benzoic acid porphyrin mania mass spectrometry material coating measurement accuracy medical decision making medical literature medical nebulizer menstrual irregularity mental health service metabolism metformin methanol methodology metoprolol microdosing microfluidic nanoprecipitation microfluidics microscopy midazolam mitochondria mitochondrial complexes mitochondrial membrane potential molecular interaction molecular model molecular stability monitoring multiple sclerosis myalgia nanodispersion formulation nanoparticle national health service nausea nebulization necrosis neurodegeneration neuroprotection nicardipine nitromethane nonhuman normal human novel psychoactive substances nucleic acids} nutrition nystagmus oadoaj oaemailed olanzapine oligodendrocyte optical density optical reflection otalgia oxidative stress pH effects pancytopenia paracetamol parkinsonism particle size patient compliance patient participation peer review peptides peroxynitrite personalised pharmacy phase transition phenazone phenobarbital phospholipid phospholipid vesicle phosphorylation photon correlation spectroscopy photosensitivity physical chemistry piracetam placebo plasma concentration-time curve poly(vinyl alcohol)-cryogel carrier} poly-pharmacy polycarbonate polydispersity index polysorbate 80 positron emission tomography precipitation prediction presenilin-1 priapism priority journal priority journal, Administration, Oral probability prolactin propafenone prostaglandin synthase inhibitor protein protein kinase protein polymorphism psychiatry psychologic assessment public health pulmicort respule quality control quality improvement quality of life quetiapine quinidine raltegravir randomized controlled trial rating scale reactor redox homeostasis redox state redox-dependent reduction refraction index resiniferatoxin respiratory chain complexes resveratrol reverse transcription polymerase chain reaction review review, Allium review, Biological Availability rhinitis saccadic eye movement salbutamol sulfate, aerosol scanning electron microscopy scanning transmission electron microscopy schizophrenia scoping self-controlled case-series method self-medication sensitivity analysis siRNA siRNA delivery side effect simulation single nucleotide polymorphism smoking solid phase extraction solid state solvation solvent solvent effect solvent, chemical engineering somnolence soybean spectral editing speech disorder statistical analysis statistical process control stoichiometry stomach disease stroke sub-classification subgenomic sugar-based surfactants sulfathiazole, aqueous solution sulfathiazole, crystal sulfoxide, catalysis sumatriptan superoxide dismutase surface property suspension symptom tachycardia tandem mass spectrometry tegmentum, Eye Movements telmisartan temperature sensitivity tenofovir thermodynamics thrombocyte aggregation inhibition thrombocytopenia thyroid hormone tolbutamide toxic epidermal necrolysis toxicology transmission electron microscopy transmucosal treatment outcome tremor triacylglycerol tricyclic tubercidin tumour xenograft tyrosine kinase inhibitor tyrphostin ultraviolet spectrophotometry unclassified drug unclassified drug, aerosol unclassified drug, area under the curve unclassified drug, article unclassified drug, bacterial strain unindexed drug valproate semisodium, accuracy vasculitis verapamil virulence, Anti-Bacterial Agents vitagenes voluntary movement, Adult volunteer warfarin water, article weight gain widefield surface plasmon resonance microscopy xerostomia zeta potential zeta potential, Anti-Inflammatory Agents zidovudine, area under the curve zk 253, adult zk 253, area under the curve
Number of items at this level: 1202.

(E) - capsaicin

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

1-methyl-4-phenylpyridinium

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

1H

Bates, Timothy E., Williams, Stephen R., Kauppinen, Risto A. and Gadian, David G. (1989) Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of neurochemistry, 53 (1). pp. 102-10. ISSN 0022-3042

Brooks, K. J., Kauppinen, R. A., Williams, S. R., Bachelard, H. S., Bates, T. E. and Gadian, D. G. (1989) Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 33 (1). pp. 185-192. ISSN 0306-4522

Gadian, D. G., Bates, T. E., Williams, S. R., Bell, J. D., Austin, S. J. and Connelly, A. (1991) Approaches to editing, assignment and interpretation of proton spectra. NMR in biomedicine, 4 (2). pp. 85-89. ISSN 0952-3480

2 amino 4 nitrophenol

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

2 propanol

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

31P

Bates, Timothy E., Williams, Stephen R. and Gadian, David G. (1989) Phosphodiesters in the liver: the effect of field strength on the 31P signal. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 12 (1). pp. 145-150. ISSN 0740-3194

Bates, Timothy E., Williams, Stephen R., Kauppinen, Risto A. and Gadian, David G. (1989) Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of neurochemistry, 53 (1). pp. 102-10. ISSN 0022-3042

Brooks, K. J., Kauppinen, R. A., Williams, S. R., Bachelard, H. S., Bates, T. E. and Gadian, D. G. (1989) Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 33 (1). pp. 185-192. ISSN 0306-4522

Murphy, Elizabeth J., Bates, Timothy E., Williams, Stephen R., Watson, Tracey, Brindle, Kevin M., Rajagopalan, Bheeshma and Radda, George K. (1992) Endoplasmic reticulum: the major contributor to the PDE peak in hepatic 31P-NMR spectra at low magnetic field strengths. Biochimica et biophysica acta: biomembranes, 1111 (1). pp. 51-58. ISSN 0005-2736

4 nitrophenol

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

5-IAI

Elie, Mathieu P., Elie, Leonie E. and Baron, Mark G. (2013) Keeping pace with NPS releases: fast GC-MS screening of legal high products. Drug Testing and Analysis, 5 (5). pp. 281-290. ISSN 1942-7603

AEA

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

AFM

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

AIDS

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2015) Adverse drug reactions and quality of life in HIV/AIDS patients: Advocacy on valuation and role of pharmacovigilance in developing countries. HIV & AIDS Review, 14 (1). pp. 28-30. ISSN 1730-1270

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2013) HIV/AIDS treatment and health related quality of life: Importance of knowing patients’ perspective. HIV & AIDS Review, 12 (1). pp. 26-27. ISSN 1730-1270

AMPA

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

ATF4

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

ATP

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Absorption enhancement

Casettari, Luca, Vllasaliu, Driton, Castagnino, Enzo, Stolnik, Snjezana, Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

Vllasaliu, Driton, Casettari, Luca, Fowler, Robyn, Exposito-Harris, Ruth, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Accelerator mass spectrometry

Lappin, G., Boyce, M. J., Matzow, T., Lociuro, S., Seymour, M. and Warrington, S. J. (2013) A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung. European Journal of Clinical Pharmacology, 69 (9). pp. 1673-1682. ISSN 0031-6970

Acid condition

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Acid-base complexation reaction

Baron, M. G., Narayanaswamy, R. and Thorpe, S. C. (1996) Hydrophobic membrane sensors for the optical determination of hydrogen chloride gas. Sensors and Actuators, B: Chemical, 34 (1-3). pp. 511-515. ISSN 0925-4005

Acne

Ryan-Kewley, Angela E., Williams, David A., Hepburn, Neill and Dixon, Ronald A. (2017) Non-antibiotic isotretinoin treatment differentially controls Propionibacterium acnes on skin of acne patients. Frontiers in Microbiology, 8 . ISSN 1664-302X

Additive manufacturing

Sadia, Muzna, Arafat, Basel, Ahmed, Waqar, Forbes, Robert E. and Alhnan, Mohamed A. (2018) Channelled tablets: an innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release, 269 . pp. 355-363. ISSN 0168-3659

Adolescent

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Adult

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Adverse drug reactions

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2015) Adverse drug reactions and quality of life in HIV/AIDS patients: Advocacy on valuation and role of pharmacovigilance in developing countries. HIV & AIDS Review, 14 (1). pp. 28-30. ISSN 1730-1270

Age related macular degeneration

Chen, C., Cano, M., Wang, J. J., Li, J., Huang, C., Yu, Q., Herbert, T. P., Handa, J. T. and Zhang, S. X. (2014) Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells. Antioxidants & Redox Signaling, 20 (14). pp. 2091-2106. ISSN 1523-0864

Aged

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Aged, 80 and over

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Alkylation

Belokon, Yuri N., Kochetkov, Konstantin A., Churkina, Tatiana D., Ikonnikov, Nikolai S., Chesnokov, Alexey A., Larionov, Oleg V., Singh, Ishwar, Parmar, Virinder S., Vyskocil, Stepan and Kagan, Henri B. (2000) Asymmetric PTC C-alkylation catalyzed by chiral derivatives of tartaric acid and aminophenols. Synthesis of (R)- and (S)-alpha-methyl amino acids. Journal of Organic Chemistry, 65 (21). pp. 7041-7048. ISSN 0022-3263

Alkylglycosides

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Alkynes

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Allium

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Allium cepa

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Allium sativum

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Alzheimer's

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

Pardon, Marie-Christine, Sarmad, Sarir, Rattray, Ivan, Bates, Timothy E., Scullion, Gillian A., Marsden, Charles A., Barrett, David A., Lowe, James and Kendall, David A. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging, 30 (7). pp. 1099-1113. ISSN 0197-4580

Amino acid

Casettari, Luca, Vllasaliu, Driton, Lam, Jenny K. W., Soliman, Mahmoud and Illum, Lisbeth (2012) Biomedical applications of amino acid-modified chitosans: a review. Biomaterials, 33 (30). pp. 7565-7583. ISSN 0142-9612

Ammonia

Brooks, K. J., Kauppinen, R. A., Williams, S. R., Bachelard, H. S., Bates, T. E. and Gadian, D. G. (1989) Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 33 (1). pp. 185-192. ISSN 0306-4522

Amphibian

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Amyloid

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Amyloidogenesis

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Anionic antimicrobial peptides

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Antibiosis

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Antibiotic resistance

Ryan-Kewley, Angela E., Williams, David A., Hepburn, Neill and Dixon, Ronald A. (2017) Non-antibiotic isotretinoin treatment differentially controls Propionibacterium acnes on skin of acne patients. Frontiers in Microbiology, 8 . ISSN 1664-302X

Anticancer

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Anticoagulants

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Antimicrobial

Harris, Frederick, Prabhu, Saurabh, R. Dennison, Sarah, J. Snape, Timothy, Lea, Robert, Mura, Manuela and A. Phoenix, David (2016) Anionic host defence peptides from the plant kingdom: their anticancer activity and mechanisms of action. Protein & Peptide Letters, 23 (8). pp. 676-687. ISSN 0929-8665

Antimicrobial agent

Perinelli, D. R., Lucarini, S., Fagioli, L., Campana, R., Vllasaliu, D., Duranti, A. and Casettari, L. (2018) Lactose oleate as new biocompatible surfactant for pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 124 . pp. 55-62. ISSN 0939-6411

Antimicrobial peptide

Iyer, Abhishek (2016) DNA recognition and antimicrobial compounds: exploring the versatility of peptides. PhD thesis, University of Lincoln.

Antioxidants

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

Anxiety

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2013) Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7 (4). pp. 191-197. ISSN 1871-4021

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2015) Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). International Journal of Diabetes in Developing Countries, 35 (3). pp. 211-218. ISSN 0973-3930

Apoptosis

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

Area Under Curve

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Article

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

Artificial organs

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Aspergillus fumigatu

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar, Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Aspirin

Stevenson, DJ, Dumbleton, JS, Avery, A, Coupland, C, Hobbs, F, Kendrick, D, Moore, MV, Rubin, GP, Smith, Murray and Hawkey, CJ (2018) The helicobacter eradication aspirin trial (HEAT): demographic data for randomised (H.pylori positive) patients. In: UEG Week, October 20-24, Vienna.

Azides

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

BSO

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Bacteriocins

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Basement membrane

Vllasaliu, Driton, Falcone, Franco H., Stolnik, Snjezana and Garnett, Martin (2014) Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules. Experimental Cell Research, 323 (1). pp. 218-231. ISSN 0014-4827

Batch Cell Culture Techniques

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Beclometasone dipropionate

Khan, Iftikhar, Yousaf, Sakib, Subramanian, Sneha, Albed Alhnan, Mohamed, Ahmed, Waqar and Elhissi, Abdelbary (2018) Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: development, characterization and stability evaluation. International Journal of Pharmaceutics . ISSN 0378-5173

Bespoke

Sadia, Muzna, Arafat, Basel, Ahmed, Waqar, Forbes, Robert E. and Alhnan, Mohamed A. (2018) Channelled tablets: an innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release, 269 . pp. 355-363. ISSN 0168-3659

Beta cell

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Biocompatibility

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Bioconjugation}

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Biological Markers

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Biomarkers

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Biosynthesis

Davis, Carol, Carberry, Stephen, Schrettl, Markus, Singh, Ishwar, Stephens, John C., Barry, Sarah M., Kavanagh, Kevin, Challis, Gregory L., Brougham, Dermot and Doyle, Sean (2011) The role of glutathione S-Transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 18 (4). pp. 542-552. ISSN 1074-5521

Bisphosphonates

Asghar, Zahid, Godoy Caballero, Ana Luisa, Pathirannehelage, S., Williams, J., McKay, Steve, Grassby, Paul, de Lusignan, S. and Siriwardena, Niro (2019) Saving bones without risking brain—bisphosphonates and risk of stroke: matched case-control study. Osteoporosis International, 30 (9). pp. 1845-1854. ISSN 0937-941X

Brain

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Gadian, D. G., Bates, T. E., Williams, S. R., Bell, J. D., Austin, S. J. and Connelly, A. (1991) Approaches to editing, assignment and interpretation of proton spectra. NMR in biomedicine, 4 (2). pp. 85-89. ISSN 0952-3480

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Brain Slices

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

Breast cancer

Osei-Baidoo, Jeremiah S. (2015) The effect of quinine products on tamoxifen resistant breast cancer cells. Masters thesis, University of Lincoln.

Bronchial alveolar lavage

Lappin, G., Boyce, M. J., Matzow, T., Lociuro, S., Seymour, M. and Warrington, S. J. (2013) A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung. European Journal of Clinical Pharmacology, 69 (9). pp. 1673-1682. ISSN 0031-6970

Butanols

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Byproducts

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

CHO cells

Abdel-Razaq, W., Bates, T. E. and Kendall, D. A. (2007) The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology, 73 (12). pp. 1995-2003. ISSN 0006-2952

CHOP

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

CNS

Hussein, Nozad, Omer, Huner, Ismael, Ava, Alhnan, Mohamed Albed, Elhissi, Abdelbary and Ahmed, Waqar (2020) Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation. Pharmaceutical Development and Technology, 25 (3). pp. 290-299. ISSN 1083-7450

COVID-19

Ahmed, Syed Imran and Khan, Shahzad (2020) Coagulopathy and Plausible Benefits of Anticoagulation Among COVID-19 Patients. Current Problems in Cardiology, 45 (9). p. 100648. ISSN 0146-2806

CYP1A1

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

Caco-2

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Vllasaliu, Driton, Casettari, Luca, Fowler, Robyn, Exposito-Harris, Ruth, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Vllasaliu, Driton, Fowler, Robyn, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Vllasaliu, Driton, Shubber, Saif, Garnett, Martin, Alexander, Cameron, Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

Caco-2 cells

Garnett, Martin, Vllasaliu, Driton, Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

Calcium depletion

Vllasaliu, Driton, Shubber, Saif, Garnett, Martin, Alexander, Cameron, Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

Calu-3

Vllasaliu, Driton, Casettari, Luca, Fowler, Robyn, Exposito-Harris, Ruth, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Vllasaliu, Driton, Exposito-Harris, Ruth, Heras, Angeles, Casettari, Luca, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Vllasaliu, Driton, Fowler, Robyn, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Vllasaliu, Driton, Shubber, Saif, Garnett, Martin, Alexander, Cameron, Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

Calu-3 cells

Shubber, Saif, Vllasaliu, Driton, Rauch, Cyril, Jordan, Faron, Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Cancer

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

Candida albicans

Pavesi, Coralie, Banks, Lucy A. and Hudaib, Taghread (2018) Antifungal and antibacterial activities of eugenol and non-polar extract of Syzygium aromaticum L. Journal of Pharmaceutical Sciences and Research, 10 (2). pp. 337-339. ISSN 0975-1459

Carbon Radioisotopes

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Carbon-Sulfur Lyases

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Cardiac

Broadley, K. J., Williams, R. G., Hawthorn, M. H. and Grassby, Paul (1984) Mechanisms of cardiac supersensitivity to sympathomimetic amines. Methods and Findings in Experimental and Clinical Pharmacology, 6 (4). pp. 179-186. ISSN 0379-0355

Catalysis

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Cell adhesion

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Cell contraction

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Cell mechanic

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Cell monolayers

Casettari, Luca, Vllasaliu, Driton, Mantovani, Guiseppe, Howdle, Steven M., Stolnik, Snow and Illum, Lisbeth (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules, 11 (11). pp. 2854-2865. ISSN 1525-7797

Cell surface morphology

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Cell surface roughness

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Cell uptake

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Cells

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Cells adhesion

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Cellular stress response

Calabrese, Vittorio, Cornelius, Carolin, Mancuso, Cesare, Pennisi, Giovanni, Calafato, Stella, Bellia, Francesco, Bates, Timothy E., Giuffrida Stella, Anna Maria, Schapira, Tony, Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

Cellular uptake

Moradi, Emilia, Vllasaliu, Driton, Garnett, Martin, Falcone, Franco and Stolnik, Snow (2012) Ligand density and clustering effects on endocytosis of folate modified nanoparticles. RSC Advances, 2 (7). pp. 3025-3033. ISSN 2046-2069

Characterisation

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Charge transfer

Seaton, Colin C., Blagden, Nicholas, Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

Chemical gas sensor

Baron, M. G., Narayanaswamy, R. and Thorpe, S. C. (1996) Hydrophobic membrane sensors for the optical determination of hydrogen chloride gas. Sensors and Actuators, B: Chemical, 34 (1-3). pp. 511-515. ISSN 0925-4005

Chemistry

Blagden, Nicholas and Davey, R. (1999) Polymorphs take shape. Chemistry in Britain, 35 (3). pp. 44-45. ISSN 0009-3106

Errington, W., Parmar, V. S., Singh, A. and Singh, I. (2001) 7-acetoxy-4-(1-chloroethyl)coumarin. Acta Crystallographica Section E - Structure Reports Online, 57 (10). O939-O940. ISSN 1600-5368

Kumar, Ajay, Husain, Mofazzal, Prasad, Ashok K., Singh, Iswar, Vats, Archana, Sharma, Nawal K., Sharma, Sunil K., Gupta, Rajinder K., Olsen, Carl E., Bracke, Marc E., Gross, Richard A. and Parmar, Virinder S. (2003) Synthesis of novel heterocyclic compounds: routes to pyrazolyl 1,2,3-triazoles and their biological activity evaluation. Indian Journal of Chemistry : Section B, Oganic Chemistry including Medicinal Chemistry, 42 (8). pp. 1950-1957. ISSN 0376-4699

Singh, Ishwar and Seitz, Oliver (2006) Diastereoselective synthesis of beta-aryl-C-nucleosides from 1,2-anhydrosugars. Organic Letters, 8 (19). pp. 4319-4322. ISSN 1523-7060

Singh, Ishwar, Zarafshani, Zoya, Heaney, Frances and Lutz, Jean-Francois (2011) Orthogonal modification of polymer chain-ends via sequential nitrile oxide-alkyne and azide-alkyne Huisgen cycloadditions. Polymer Chemistry, 2 (2). pp. 372-375. ISSN 1759-9954

Singh, Ishwar, Zarafshani, Zoya, Lutz, Jean-Francois and Heaney, Frances (2009) Metal-Free "Click'' chemistry: efficient polymer modification via 1,3-dipolar cycloaddition of nitrile oxides and alkynes. Macromolecules, 42 (15). pp. 5411-5413. ISSN 0024-9297

Wendeln, Christian, Singh, Ishwar, Rinnen, Stefan, Schulz, Christian, Arlinghaus, Heinrich F., Burley, Glenn A. and Ravoo, Bart Jan (2012) Orthogonal, metal-free surface modification by strain-promoted azide-alkyne and nitrile oxide-alkene/alkyne cycloadditions. Chemical Science, 3 (8). pp. 2479-2484. ISSN 2041-6520

Chemistry, Pharmaceutical

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Chemotherapy

Illes, Bernhard, Wuttke, Stefan and Engelke, Hanna (2017) Liposome-coated iron fumarate metal-organic framework nanoparticles for combination therapy. Nanomaterials (Basel, Switzerland), 7 (11). ISSN 2079-4991

Chitosan

Casettari, Luca, Vllasaliu, Driton, Castagnino, Enzo, Stolnik, Snjezana, Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

Casettari, Luca, Vllasaliu, Driton, Lam, Jenny K. W., Soliman, Mahmoud and Illum, Lisbeth (2012) Biomedical applications of amino acid-modified chitosans: a review. Biomaterials, 33 (30). pp. 7565-7583. ISSN 0142-9612

Cole, Hannah (2016) Chitosan-mediated vaccine delivery through the intestinal epithelium. Masters thesis, University of Lincoln.

Vllasaliu, Driton, Casettari, Luca, Fowler, Robyn, Exposito-Harris, Ruth, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Vllasaliu, Driton, Exposito-Harris, Ruth, Heras, Angeles, Casettari, Luca, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Chloroquine

Osei-Baidoo, Jeremiah S. (2015) The effect of quinine products on tamoxifen resistant breast cancer cells. Masters thesis, University of Lincoln.

Cholesteryl esters

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Chromatography, Liquid

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Cinchona pubescens

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Click reaction

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Clinical trial

Stevenson, DJ, Dumbleton, JS, Avery, A, Coupland, C, Hobbs, F, Kendrick, D, Moore, MV, Rubin, GP, Smith, Murray and Hawkey, CJ (2018) The helicobacter eradication aspirin trial (HEAT): demographic data for randomised (H.pylori positive) patients. In: UEG Week, October 20-24, Vienna.

Co-crystal

Kulkarni, Chaitrali, Wood, Clive, Kelly, Adrian L., Gough, Tim, Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

Coagulopathy

Ahmed, Syed Imran and Khan, Shahzad (2020) Coagulopathy and Plausible Benefits of Anticoagulation Among COVID-19 Patients. Current Problems in Cardiology, 45 (9). p. 100648. ISSN 0146-2806

Complex I

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Complexes

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Computer simulation

Davey, R. J., Blagden, N., Righini, S., Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

Control charts

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

Cross-Over Studies

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Crystal engineering

Seaton, Colin C., Blagden, Nicholas, Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

Crystal interfaces

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Crystal structure

David, W. I. F., Shankland, K., Pulham, C. R., Blagden, N., Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

Crystallisation

Lucaioli, Paolo, Nauha, Elisa, Singh, Ishwar and Blagden, Nicholas (2018) First steps for the direct purification of L-Leu-L-Leu dipeptide through co-crystallisation. Crystal Growth & Design, 18 (2). pp. 1062-1069. ISSN 1528-7483

Crystallization

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Davey, R. J., Blagden, N., Righini, S., Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

Crystallography, X-Ray

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Crystals

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

Davey, R. J. and Blagden, N. (1999) Computational approaches to crystal engineering. Journal of Pharmacy and Pharmacology, 51 (SUPPL.). p. 2. ISSN 0022-3573

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Cycloaddition

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

D-mannitol

Khan, Iftikhar, Yousaf, Sakib, Subramanian, Sneha, Albed Alhnan, Mohamed, Ahmed, Waqar and Elhissi, Abdelbary (2018) Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: development, characterization and stability evaluation. International Journal of Pharmaceutics . ISSN 0378-5173

D2 receptor

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

D3 receptor

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

DNA

Kohler, O., Jarikote, D. V., Singh, I., Parmar, V. S., Weinhold, E. and Seitz, O. (2005) Forced intercalation as a tool in gene diagnostics and in studying DNA-protein interactions. Pure and Applied Chemistry, 77 (1). pp. 327-338. ISSN 0033-4545

Krpetic, Zeljka, Singh, Ishwar, Su, Wu, Guerrini, Luca, Faulds, Karen, Burley, Glenn A. and Graham, Duncan (2012) Directed assembly of DNA-functionalized gold nanoparticles using pyrrole-imidazole polyamides. Journal of the American Chemical Society, 134 (20). pp. 8356-8359. ISSN 0002-7863

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Singh, I., Beuck, C., Bhattacharya, A., Hecker, W., Parmar, V. S., Weinhold, E. and Seitz, O. (2004) Abasic site stabilization by aromatic DNA base surrogates: High-affinity binding to a baseflipping DNA-methyltransferase. Pure and Applied Chemistry, 76 (7-8). pp. 1563-1570. ISSN 0033-4545

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Singh, Ishwar and Heaney, Frances (2011) Solid phase strain promoted "click'' modification of DNA via [3+2]-nitrile oxide-cyclooctyne cycloadditions. Chemical Communications, 47 (9). pp. 2706-2708. ISSN 1359-7345

Singh, Ishwar, Hecker, Walburga, Prasad, Ashok K., Parmara, Virinder S. and Seitz, Oliver (2002) Local disruption of DNA-base stacking by bulky base surrogates. Chemical Communications (5). pp. 500-501. ISSN 1359-7345

Singh, Ishwar, Wendeln, Christian, Clark, Alasdair W., Cooper, Jonathan M., Ravoo, Bart Jan and Burley, Glenn A. (2013) Sequence-selective detection of double-stranded DNA sequences using pyrrole-imidazole polyamide microarrays. Journal of the American Chemical Society, 135 (9). pp. 3449-3457. ISSN 0002-7863

DNA Virus

Field, Hugh J., Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

DNA methylation

Beuck, C, Singh, I., Bhattacharya, A, Heckler, W, Parmar, VS, Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

DNA-protein interactions

Beuck, C, Singh, I., Bhattacharya, A, Heckler, W, Parmar, VS, Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

Delta-9-tetrahydrocannabinol

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

Depression

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2013) Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7 (4). pp. 191-197. ISSN 1871-4021

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2015) Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). International Journal of Diabetes in Developing Countries, 35 (3). pp. 211-218. ISSN 0973-3930

Derivatisation

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Derivative

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Diabetes

Barlow, A. D., Nicholson, M. L. and Herbert, T. P. (2013) Evidence for rapamycin toxicity in pancreatic b-Cells and a review of the underlying molecular mechanisms. Diabetes, 62 (8). pp. 2674-2682. ISSN 0012-1797

Herbert, T. P. and Laybutt, D. R. (2016) A reevaluation of the role of the unfolded protein response in islet dysfunction: maladaptation or a failure to adapt? Diabetes, 65 (6). pp. 1472-1480. ISSN 0012-1797

Selway, J., Rigatti, R., Storey, N., Lu, J., Willars, G. B. and Herbert, T. P. (2012) Evidence that Ca 2+ within the microdomain of the l-type voltage gated Ca 2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1. PLoS ONE, 7 (3). 0033004. ISSN 1932-6203

Diabetes mellitus

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Diaminopyrimidine antibiotic

Lappin, G., Boyce, M. J., Matzow, T., Lociuro, S., Seymour, M. and Warrington, S. J. (2013) A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung. European Journal of Clinical Pharmacology, 69 (9). pp. 1673-1682. ISSN 0031-6970

Disease Progression

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Dissolution

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Dissolution rates

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Dodecylmaltoside

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Dog

van Ravenzwaay, B., Hardwick, T. D., Needham, D., Pethen, S. and Lappin, G. J. (2003) Comparative metabolism of 2,4-dichlorophenoxyacetic acid (2,4-D) in rat and dog. Xenobiotica: the fate of foreign compounds in biological systems, 33 (8). pp. 805-21. ISSN 0049-8254

Dose linearity

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Dose-Response Relationship, Drug

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Drug Design

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Drug Monitoring

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Drug Stability

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Drug Storage

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Drug delivery

Bird, Joanna (2015) Neurotensin: a candidate for peptide-guided drug delivery. MRes thesis, University of Lincoln.

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Casettari, Luca, Vllasaliu, Driton, Castagnino, Enzo, Stolnik, Snjezana, Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

Casettari, Luca, Vllasaliu, Driton, Lam, Jenny K. W., Soliman, Mahmoud and Illum, Lisbeth (2012) Biomedical applications of amino acid-modified chitosans: a review. Biomaterials, 33 (30). pp. 7565-7583. ISSN 0142-9612

Garnett, Martin, Vllasaliu, Driton, Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

Illes, Bernhard, Hirschle, Patrick, Barnert, Sabine, Cauda, Valentina, Wuttke, Stefan and Engelke, Hanna (2017) Exosome-coated metal–organic framework nanoparticles: an efficient drug delivery platform. Chemistry of Materials, 29 (19). pp. 8042-8046. ISSN 0897-4756

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

Drug development

Burt, T., Yoshida, K., Lappin, G., Vuong, L., John, C., de Wildt, S. N., Sugiyama, Y. and Rowland, M. (2016) Microdosing and other phase 0 clinical trials: facilitating translation in Drug Development. Clinical and Translational Science, 9 (2). pp. 74-88. ISSN 1752-8054

Drug products

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Drug products plants

Davey, R. J., Blagden, N., Righini, S., Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

Dyes

Baron, M. G. and Elie, M. (2003) Temperature sensing using reversible thermochromic polymeric films. Sensors and Actuators, B: Chemical, 90 (1-3). pp. 271-275. ISSN 0925-4005

E-cigarette

Bareham, David, Ahmadi, Keivan, Elie, Mathieu, Jones, Arwel and Mckee, Martin (2018) E-cigarettes: further flavours of controversy within the controversy. Lancet Respiratory Medicine, 6 (1). pp. 16-17. ISSN 2213-2600

EM

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

EPHX1

Daci, Armond, Beretta, Giangiacomo, Vllasaliu, Driton, Shala, Aida, Govori, Valbona, Norata, Giuseppe and Krasniqi, Shaip (2015) Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar Albanian epileptic patients. PLOS ONE . ISSN 1932-6203

ER stress

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

Elastic properties

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Elasticity

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Electron Microscopy

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Electron Transport Chain

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Almeida, A., Brooks, K. J., Sammut, I., Keelan, J., Davey, G. P., Clark, J. B. and Bates, T. E. (1995) Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Developmental Neuroscience, 17 (4). pp. 212-218. ISSN 0378-5866

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Electronic Clinical-Patient Dataset.

Asghar, Zahid, Godoy Caballero, Ana Luisa, Pathirannehelage, S., Williams, J., McKay, Steve, Grassby, Paul, de Lusignan, S. and Siriwardena, Niro (2019) Saving bones without risking brain—bisphosphonates and risk of stroke: matched case-control study. Osteoporosis International, 30 (9). pp. 1845-1854. ISSN 0937-941X

Endocytosis

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Enterococcus faecium

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Enzymatic synthesis

Perinelli, D. R., Lucarini, S., Fagioli, L., Campana, R., Vllasaliu, D., Duranti, A. and Casettari, L. (2018) Lactose oleate as new biocompatible surfactant for pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 124 . pp. 55-62. ISSN 0939-6411

Enzymes

Rose, Peter, Faulkner, Kathy, Williamson, Gary and Mithen, Gary (2000) 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis, 21 (11). pp. 1983-1988. ISSN 0143-3334

Epilepsy

Ngomba, Richard Teke and van Luijtelaar, Gilles (2018) Metabotropic glutamate receptors as drug targets for the treatment of absence epilepsy. Current Opinion in Pharmacology, 38 . pp. 43-50. ISSN 1471-4892

Epipolythiodioxopiperazine

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar, Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Epithelial barrier

Vllasaliu, Driton, Fowler, Robyn, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Epithelial cells

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Epithelial models

Garnett, Martin, Vllasaliu, Driton, Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

Epithelial permeability

Garnett, Martin, Vllasaliu, Driton, Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Escherichia coli

Pavesi, Coralie, Banks, Lucy A. and Hudaib, Taghread (2018) Antifungal and antibacterial activities of eugenol and non-polar extract of Syzygium aromaticum L. Journal of Pharmaceutical Sciences and Research, 10 (2). pp. 337-339. ISSN 0975-1459

Estradiol

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Eugenol

Pavesi, Coralie, Banks, Lucy A. and Hudaib, Taghread (2018) Antifungal and antibacterial activities of eugenol and non-polar extract of Syzygium aromaticum L. Journal of Pharmaceutical Sciences and Research, 10 (2). pp. 337-339. ISSN 0975-1459

Excipients

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Extracellular matrix protein

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

FTIR

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Fanconi renotubular syndrome

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

FcRn pathway

Vllasaliu, Driton, Alexander, Cameron, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2012) Fc-mediated transport of nanoparticles across airway epithelial cell layers. Journal of Controlled Release, 158 (3). pp. 479-486. ISSN 0168-3659

Focal adhesions

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Folate ligands

Moradi, Emilia, Vllasaliu, Driton, Garnett, Martin, Falcone, Franco and Stolnik, Snow (2012) Ligand density and clustering effects on endocytosis of folate modified nanoparticles. RSC Advances, 2 (7). pp. 3025-3033. ISSN 2046-2069

Food Microbiology

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Foodborne Diseases

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Forensic Science

Elie, Leonie, Elie, Mathieu, Cave, Gareth, Vetter, Marleen, Croxton, Ruth and Baron, Mark (2016) Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances. Journal of Raman Spectroscopy, 47 (11). pp. 1343-1350. ISSN 0377-0486

Fracture

Asghar, Zahid, Godoy Caballero, Ana Luisa, Pathirannehelage, S., Williams, J., McKay, Steve, Grassby, Paul, de Lusignan, S. and Siriwardena, Niro (2019) Saving bones without risking brain—bisphosphonates and risk of stroke: matched case-control study. Osteoporosis International, 30 (9). pp. 1845-1854. ISSN 0937-941X

Fructose

Bates, T. E., Williams, S. R., Busza, A. L., Gadian, D. G. and Proctor, E. (1988) A 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR in biomedicine, 1 (2). pp. 67-73. ISSN 0952-3480

Funnel plots

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

GABA Modulators

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

GC-MS

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

GCM

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

GHB concentration

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

GSH

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

GSIS

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Gamma-hydroxybutyrate

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Gene delivery

Casettari, Luca, Vllasaliu, Driton, Castagnino, Enzo, Stolnik, Snjezana, Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

Gene therapy

Casettari, Luca, Vllasaliu, Driton, Lam, Jenny K. W., Soliman, Mahmoud and Illum, Lisbeth (2012) Biomedical applications of amino acid-modified chitosans: a review. Biomaterials, 33 (30). pp. 7565-7583. ISSN 0142-9612

Glass

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Gliotoxin

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar, Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Glutamate receptors

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

Glutathione

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Glycosides

Hainke, Sven, Singh, Ishwar, Hemmings, Jennifer and Seitz, Oliver (2007) Synthesis of C-aryl-nucleosides and O-aryl-glycosides via cuprate glycosylation. Journal of Organic Chemistry, 72 (23). pp. 8811-8819. ISSN 0022-3263

Good correlations

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Great Britain

Alnahar, Saja, Elliott, Rachel A. and Smith, Murray D. (2017) Biosimilar uptake by British local formularies: a cross sectional study. International Journal of Clinical Pharmacy, 39 (5). pp. 1055-1060. ISSN 2210-7703

Guinea pig ileum

Broadley, Kenneth J. and Grassby, Paul F. (1985) Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition. Naunyn-Schmiedeberg's Archives of Pharmacology, 331 (4). pp. 316-323. ISSN 0028-1298

H202

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

H460

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

HIV

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2015) Adverse drug reactions and quality of life in HIV/AIDS patients: Advocacy on valuation and role of pharmacovigilance in developing countries. HIV & AIDS Review, 14 (1). pp. 28-30. ISSN 1730-1270

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2013) HIV/AIDS treatment and health related quality of life: Importance of knowing patients’ perspective. HIV & AIDS Review, 12 (1). pp. 26-27. ISSN 1730-1270

HU 210

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

Health related quality of life

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2015) Adverse drug reactions and quality of life in HIV/AIDS patients: Advocacy on valuation and role of pharmacovigilance in developing countries. HIV & AIDS Review, 14 (1). pp. 28-30. ISSN 1730-1270

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2013) HIV/AIDS treatment and health related quality of life: Importance of knowing patients’ perspective. HIV & AIDS Review, 12 (1). pp. 26-27. ISSN 1730-1270

Heart

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Helicobacter pylori

Stevenson, DJ, Dumbleton, JS, Avery, A, Coupland, C, Hobbs, F, Kendrick, D, Moore, MV, Rubin, GP, Smith, Murray and Hawkey, CJ (2018) The helicobacter eradication aspirin trial (HEAT): demographic data for randomised (H.pylori positive) patients. In: UEG Week, October 20-24, Vienna.

High-resolution imaging

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Human keratinocytes

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Humans

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Huntington Disease

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Huntington chorea

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Hydrocortisone

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Hydrogen bonds

Seaton, Colin C., Blagden, Nicholas, Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

Hydrogen chloride

Baron, M. G., Narayanaswamy, R. and Thorpe, S. C. (1996) Hydrophobic membrane sensors for the optical determination of hydrogen chloride gas. Sensors and Actuators, B: Chemical, 34 (1-3). pp. 511-515. ISSN 0925-4005

Hydrogen peroxide

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Hydroxybutyrate

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

IgG

Vllasaliu, Driton, Alexander, Cameron, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2012) Fc-mediated transport of nanoparticles across airway epithelial cell layers. Journal of Controlled Release, 158 (3). pp. 479-486. ISSN 0168-3659

Image reconstruction

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Imaging systems

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Immumnoelectron microscopy

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Immunocytochemistry

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Immunofluorescence staining

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

In situ crystallization

David, W. I. F., Shankland, K., Pulham, C. R., Blagden, N., Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

Injection

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Injection port

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Injections, Intravenous

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Integrins

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Interfacial interaction

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Intra-arterial microdosing

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Ischaemia

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

Ischemia

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

Islet

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Islet transplantation

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Isotopes

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

JCNotOpen

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

JCOpen

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Capel, Victoria, Vllasaliu, Driton, Watts, Peter and Stolnik, Snow (2016) Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency. Biochemical and Biophysical Research Communications, 477 (2). pp. 260-265. ISSN 0006-291X

Daci, Armond, Beretta, Giangiacomo, Vllasaliu, Driton, Shala, Aida, Govori, Valbona, Norata, Giuseppe and Krasniqi, Shaip (2015) Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar Albanian epileptic patients. PLOS ONE . ISSN 1932-6203

Shubber, Saif, Vllasaliu, Driton, Rauch, Cyril, Jordan, Faron, Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

Telford, Richard, Seaton, Colin C., Clout, Alexander, Buanz, Asma, Gaisford, Simon, Williams, Gareth R., Prior, Timothy J., Okoye, Chidera H., Munshi, Tasnim and Scowen, Ian J. (2016) Stabilisation of metastable polymorphs: the case of paracetamol form III. Chemical Communications, 52 (81). pp. 12028-12031. ISSN 1359-7345

Vllasaliu, Driton, Falcone, Franco H., Stolnik, Snjezana and Garnett, Martin (2014) Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules. Experimental Cell Research, 323 (1). pp. 218-231. ISSN 0014-4827

Keratinocytes

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Kidney

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Kinetics

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

L-buthionine sulfoximine

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Lactose monoester

Perinelli, D. R., Lucarini, S., Fagioli, L., Campana, R., Vllasaliu, D., Duranti, A. and Casettari, L. (2018) Lactose oleate as new biocompatible surfactant for pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 124 . pp. 55-62. ISSN 0939-6411

Ligand density

Moradi, Emilia, Vllasaliu, Driton, Garnett, Martin, Falcone, Franco and Stolnik, Snow (2012) Ligand density and clustering effects on endocytosis of folate modified nanoparticles. RSC Advances, 2 (7). pp. 3025-3033. ISSN 2046-2069

Linear elasticity

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Liposome

Khan, Iftikhar, Yousaf, Sakib, Subramanian, Sneha, Albed Alhnan, Mohamed, Ahmed, Waqar and Elhissi, Abdelbary (2018) Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: development, characterization and stability evaluation. International Journal of Pharmaceutics . ISSN 0378-5173

Liposomes

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

Liquid crystals

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Listeria

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Liver

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Bates, Timothy E., Williams, Stephen R. and Gadian, David G. (1989) Phosphodiesters in the liver: the effect of field strength on the 31P signal. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 12 (1). pp. 145-150. ISSN 0740-3194

Murphy, Elizabeth J., Bates, Timothy E., Williams, Stephen R., Watson, Tracey, Brindle, Kevin M., Rajagopalan, Bheeshma and Radda, George K. (1992) Endoplasmic reticulum: the major contributor to the PDE peak in hepatic 31P-NMR spectra at low magnetic field strengths. Biochimica et biophysica acta: biomembranes, 1111 (1). pp. 51-58. ISSN 0005-2736

Lung

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

MMSY2

Herbert, Terence and Hecht, N.B. (1999) The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs. Nucleic acids research, 27 (7). pp. 1747-1753. ISSN 0305-1048

MPP+

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

MPTP

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

MRS

Bates, T. E., Williams, S. R., Busza, A. L., Gadian, D. G. and Proctor, E. (1988) A 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR in biomedicine, 1 (2). pp. 67-73. ISSN 0952-3480

Macromolecular permeability

Vllasaliu, Driton, Fowler, Robyn, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Magnetic field strength

Bates, Timothy E., Williams, Stephen R. and Gadian, David G. (1989) Phosphodiesters in the liver: the effect of field strength on the 31P signal. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 12 (1). pp. 145-150. ISSN 0740-3194

Malaysia

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2013) Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7 (4). pp. 191-197. ISSN 1871-4021

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2015) Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). International Journal of Diabetes in Developing Countries, 35 (3). pp. 211-218. ISSN 0973-3930

Hassali, Mohamed Azmi, Shafie, Asrul Akmal, Awaisu, Ahmed, Mohamed Ibrahim, Mohamed Izham and Ahmed, Syed Imran (2009) A Public Health Pharmacy Course at a Malaysian Pharmacy School. American Journal of Pharmaceutical Education, 73 (7). p. 136. ISSN 0002-9459

Mammalia

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Marijuana Smoking

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Mass spectrometry

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Mechanics

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Medical applications

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Medicinal chemistr

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Membranolysis

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Mental health

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2015) Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). International Journal of Diabetes in Developing Countries, 35 (3). pp. 211-218. ISSN 0973-3930

Metabolism

Lappin, Graham (2011) Microdosing: pharmacokinetic and metabolism data early in the drug development process. In: Pharmacokinetics in drug development: advanves and applications. Pharmacokinetics in Drug Development (3). Springer, New York. ISBN 9781441979377

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

van Ravenzwaay, B., Hardwick, T. D., Needham, D., Pethen, S. and Lappin, G. J. (2003) Comparative metabolism of 2,4-dichlorophenoxyacetic acid (2,4-D) in rat and dog. Xenobiotica: the fate of foreign compounds in biological systems, 33 (8). pp. 805-21. ISSN 0049-8254

Metal free porphyrin

Baron, M. G., Narayanaswamy, R. and Thorpe, S. C. (1996) Hydrophobic membrane sensors for the optical determination of hydrogen chloride gas. Sensors and Actuators, B: Chemical, 34 (1-3). pp. 511-515. ISSN 0925-4005

Metastable polymorphs

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Methane

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Microcrystalline test

Elie, Leonie, Elie, Mathieu, Cave, Gareth, Vetter, Marleen, Croxton, Ruth and Baron, Mark (2016) Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances. Journal of Raman Spectroscopy, 47 (11). pp. 1343-1350. ISSN 0377-0486

Microdose

Lappin, G., Boyce, M. J., Matzow, T., Lociuro, S., Seymour, M. and Warrington, S. J. (2013) A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung. European Journal of Clinical Pharmacology, 69 (9). pp. 1673-1682. ISSN 0031-6970

Microdosing

Lappin, Graham (2010) Pharmacokinetics II: 14C-labelled microdosing in assessing drug pharmacokinetics at phase-0. In: Clinical Pharmacology, Current Topics and Case Studies. Springer, pp. 155-165. ISBN 9783709101438

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Microspheres

Hussein, Nozad, Omer, Huner, Ismael, Ava, Alhnan, Mohamed Albed, Elhissi, Abdelbary and Ahmed, Waqar (2020) Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation. Pharmaceutical Development and Technology, 25 (3). pp. 290-299. ISSN 1083-7450

Middle Aged

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Mitochondria

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Molecular Structure

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Mucoadhesion

Vllasaliu, Driton, Casettari, Luca, Fowler, Robyn, Exposito-Harris, Ruth, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Mucosal delivery

Vllasaliu, Driton, Alexander, Cameron, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2012) Fc-mediated transport of nanoparticles across airway epithelial cell layers. Journal of Controlled Release, 158 (3). pp. 479-486. ISSN 0168-3659

Vllasaliu, Driton, Fowler, Robyn, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Mucosal protein delivery

Shubber, Saif, Vllasaliu, Driton, Rauch, Cyril, Jordan, Faron, Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

Vllasaliu, Driton, Shubber, Saif, Garnett, Martin, Alexander, Cameron, Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

Multicomponent crystals

Seaton, Colin C., Blagden, Nicholas, Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

Multiplex Polymerase Chain Reaction

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

N omega-nitro-L-arginine

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

NMR

Murphy, Elizabeth J., Bates, Timothy E., Williams, Stephen R., Watson, Tracey, Brindle, Kevin M., Rajagopalan, Bheeshma and Radda, George K. (1992) Endoplasmic reticulum: the major contributor to the PDE peak in hepatic 31P-NMR spectra at low magnetic field strengths. Biochimica et biophysica acta: biomembranes, 1111 (1). pp. 51-58. ISSN 0005-2736

NMR Spectroscopy

Bates, T. E., Williams, S. R., Busza, A. L., Gadian, D. G. and Proctor, E. (1988) A 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR in biomedicine, 1 (2). pp. 67-73. ISSN 0952-3480

Bates, Timothy E., Williams, Stephen R., Kauppinen, Risto A. and Gadian, David G. (1989) Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of neurochemistry, 53 (1). pp. 102-10. ISSN 0022-3042

Gadian, D. G., Bates, T. E., Williams, S. R., Bell, J. D., Austin, S. J. and Connelly, A. (1991) Approaches to editing, assignment and interpretation of proton spectra. NMR in biomedicine, 4 (2). pp. 85-89. ISSN 0952-3480

NMR spectroscopy

Brooks, K. J., Kauppinen, R. A., Williams, S. R., Bachelard, H. S., Bates, T. E. and Gadian, D. G. (1989) Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 33 (1). pp. 185-192. ISSN 0306-4522

NOS

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

NRPS

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar, Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Nanomedicines

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

Nanoparticle transport

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Vllasaliu, Driton, Alexander, Cameron, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2012) Fc-mediated transport of nanoparticles across airway epithelial cell layers. Journal of Controlled Release, 158 (3). pp. 479-486. ISSN 0168-3659

Nanoparticles

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Vllasaliu, Driton, Exposito-Harris, Ruth, Heras, Angeles, Casettari, Luca, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

Nanotechnology

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Nanotoxicity

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Nasal drug delivery

Vllasaliu, Driton, Exposito-Harris, Ruth, Heras, Angeles, Casettari, Luca, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Nested Matched Case Control study

Asghar, Zahid, Godoy Caballero, Ana Luisa, Pathirannehelage, S., Williams, J., McKay, Steve, Grassby, Paul, de Lusignan, S. and Siriwardena, Niro (2019) Saving bones without risking brain—bisphosphonates and risk of stroke: matched case-control study. Osteoporosis International, 30 (9). pp. 1845-1854. ISSN 0937-941X

New Psychoactive Substances

Elie, Leonie, Elie, Mathieu, Cave, Gareth, Vetter, Marleen, Croxton, Ruth and Baron, Mark (2016) Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances. Journal of Raman Spectroscopy, 47 (11). pp. 1343-1350. ISSN 0377-0486

Nitric Oxide Synthase

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Nitroparaffins

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Non-ionic surfactants

Perinelli, D. R., Lucarini, S., Fagioli, L., Campana, R., Vllasaliu, D., Duranti, A. and Casettari, L. (2018) Lactose oleate as new biocompatible surfactant for pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 124 . pp. 55-62. ISSN 0939-6411

Nootropic Agents

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Nose

Hussein, Nozad, Omer, Huner, Ismael, Ava, Alhnan, Mohamed Albed, Elhissi, Abdelbary and Ahmed, Waqar (2020) Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation. Pharmaceutical Development and Technology, 25 (3). pp. 290-299. ISSN 1083-7450

NotOAChecked

Bannunah, Azzah M., Vllasaliu, Driton, Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Burt, T., Yoshida, K., Lappin, G., Vuong, L., John, C., de Wildt, S. N., Sugiyama, Y. and Rowland, M. (2016) Microdosing and other phase 0 clinical trials: facilitating translation in Drug Development. Clinical and Translational Science, 9 (2). pp. 74-88. ISSN 1752-8054

Elie, Leonie, Elie, Mathieu, Cave, Gareth, Vetter, Marleen, Croxton, Ruth and Baron, Mark (2016) Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances. Journal of Raman Spectroscopy, 47 (11). pp. 1343-1350. ISSN 0377-0486

Garnett, Martin, Vllasaliu, Driton, Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

Harris, Frederick, Prabhu, Saurabh, R. Dennison, Sarah, J. Snape, Timothy, Lea, Robert, Mura, Manuela and A. Phoenix, David (2016) Anionic host defence peptides from the plant kingdom: their anticancer activity and mechanisms of action. Protein & Peptide Letters, 23 (8). pp. 676-687. ISSN 0929-8665

Kulkarni, Chaitrali, Wood, Clive, Kelly, Adrian L., Gough, Tim, Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

Lappin, Graham (2016) Approaches to intravenous clinical pharmacokinetics: recent developments with isotopic microtracers. The Journal of Clinical Pharmacology, 56 (1). pp. 11-23. ISSN 0091-2700

Lucarini, Simone, Fagioli, Laura, Campana, Raffaella, Cole, Hannah, Duranti, Andrea, Baffone, Wally, Vllasaliu, Driton and Casettari, Luca (2016) Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity. European Journal of Pharmaceutics and Biopharmaceutics, 107 . pp. 88-96. ISSN 0939-6411

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

Novel applications

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Nuclear physics

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Nucleation

Davey, R. J., Blagden, N., Righini, S., Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

Nucleosides

Algay, Virginie, Singh, Ishwar and Heaney, Frances (2010) Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition. Organic and Biomolecular Chemistry, 8 (2). pp. 391-397. ISSN 1477-0520

Hainke, Sven, Singh, Ishwar, Hemmings, Jennifer and Seitz, Oliver (2007) Synthesis of C-aryl-nucleosides and O-aryl-glycosides via cuprate glycosylation. Journal of Organic Chemistry, 72 (23). pp. 8811-8819. ISSN 0022-3263

Singh, Ishwar and Heaney, Frances (2010) Metal free, "click and click-click'' conjugation of ribonucleosides and 2'-OMe oligoribonucleotides on the solid phase. Organic and Biomolecular Chemistry, 8 (2). pp. 451-456. ISSN 1477-0520

Nucleotides

Algay, Virginie, Singh, Ishwar and Heaney, Frances (2010) Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition. Organic and Biomolecular Chemistry, 8 (2). pp. 391-397. ISSN 1477-0520

Bethge, Lucas, Singh, Ishwar and Seitz, Oliver (2010) Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization. Organic and Biomolecular Chemistry, 8 (10). pp. 2439-2448. ISSN 1477-0520

Singh, Ishwar and Heaney, Frances (2010) Metal free, "click and click-click'' conjugation of ribonucleosides and 2'-OMe oligoribonucleotides on the solid phase. Organic and Biomolecular Chemistry, 8 (2). pp. 451-456. ISSN 1477-0520

Nystagmus, Pathologic

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

ONJ

Asghar, Zahid, Godoy Caballero, Ana Luisa, Pathirannehelage, S., Williams, J., McKay, Steve, Grassby, Paul, de Lusignan, S. and Siriwardena, Niro (2019) Saving bones without risking brain—bisphosphonates and risk of stroke: matched case-control study. Osteoporosis International, 30 (9). pp. 1845-1854. ISSN 0937-941X

ORF3 polypeptide

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1996) Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA. Journal of General Virology, 77 (1). pp. 123-127. ISSN 0022-1317

Ocular Motility Disorders

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Oligonucleotides

Bethge, Lucas, Singh, Ishwar and Seitz, Oliver (2010) Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization. Organic and Biomolecular Chemistry, 8 (10). pp. 2439-2448. ISSN 1477-0520

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Singh, Ishwar, Vyle, Joseph S. and Heaney, Frances (2009) Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation. Chemical Communications, 45 (22). pp. 3276-3278. ISSN 1359-7345

Oligoribonucleotides

Singh, Ishwar and Heaney, Frances (2010) Metal free, "click and click-click'' conjugation of ribonucleosides and 2'-OMe oligoribonucleotides on the solid phase. Organic and Biomolecular Chemistry, 8 (2). pp. 451-456. ISSN 1477-0520

Operating ranges

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Optimisation

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Optimization

David, W. I. F., Shankland, K., Pulham, C. R., Blagden, N., Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

Oxidative Phosphorylation

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Oxidative Stress

Heales, S. J., Davies, S. E., Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Oxidative injury

Chen, C., Cano, M., Wang, J. J., Li, J., Huang, C., Yu, Q., Herbert, T. P., Handa, J. T. and Zhang, S. X. (2014) Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells. Antioxidants & Redox Signaling, 20 (14). pp. 2091-2106. ISSN 1523-0864

PEG

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

PEG-g-chitosan

Casettari, Luca, Vllasaliu, Driton, Castagnino, Enzo, Stolnik, Snjezana, Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

PEGylated nanomedicines

Vllasaliu, Driton, Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

PEGylation

Casettari, Luca, Vllasaliu, Driton, Castagnino, Enzo, Stolnik, Snjezana, Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

PERK

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

PINCER

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

PKA

Xie, J., Ponuwei, G.A., Moore, C.E., Willars, G.B., Tee, A.R. and Herbert, Terence (2011) CAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. Cellular Signalling, 23 (12). pp. 1927-1935. ISSN 0898-6568

PKB

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Parkinson's disease

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

Particle morphology, Crystal engineering

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Patient safety and medication

Laparidou, Despina, Chuter, Antony, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: International Society for Quality in Health Care Conference, 1 - 4 October 2017, London.

Patient-centred

Sadia, Muzna, Arafat, Basel, Ahmed, Waqar, Forbes, Robert E. and Alhnan, Mohamed A. (2018) Channelled tablets: an innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release, 269 . pp. 355-363. ISSN 0168-3659

Patient-specific

Sadia, Muzna, Arafat, Basel, Ahmed, Waqar, Forbes, Robert E. and Alhnan, Mohamed A. (2018) Channelled tablets: an innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release, 269 . pp. 355-363. ISSN 0168-3659

Patients’ perspective

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2013) HIV/AIDS treatment and health related quality of life: Importance of knowing patients’ perspective. HIV & AIDS Review, 12 (1). pp. 26-27. ISSN 1730-1270

Pediatric microdosing

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Permeability enhancement

Casettari, Luca, Vllasaliu, Driton, Mantovani, Guiseppe, Howdle, Steven M., Stolnik, Snow and Illum, Lisbeth (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules, 11 (11). pp. 2854-2865. ISSN 1525-7797

Permeability enhancer

Perinelli, D. R., Lucarini, S., Fagioli, L., Campana, R., Vllasaliu, D., Duranti, A. and Casettari, L. (2018) Lactose oleate as new biocompatible surfactant for pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 124 . pp. 55-62. ISSN 0939-6411

Permeability enhancers

Lucarini, Simone, Fagioli, Laura, Campana, Raffaella, Cole, Hannah, Duranti, Andrea, Baffone, Wally, Vllasaliu, Driton and Casettari, Luca (2016) Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity. European Journal of Pharmaceutics and Biopharmaceutics, 107 . pp. 88-96. ISSN 0939-6411

Permeation enhancer

Vllasaliu, Driton, Exposito-Harris, Ruth, Heras, Angeles, Casettari, Luca, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Permeation enhancers

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Pharmaceutical Preparations

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Pharmaceutical solids

Telford, Richard, Seaton, Colin C., Clout, Alexander, Buanz, Asma, Gaisford, Simon, Williams, Gareth R., Prior, Timothy J., Okoye, Chidera H., Munshi, Tasnim and Scowen, Ian J. (2016) Stabilisation of metastable polymorphs: the case of paracetamol form III. Chemical Communications, 52 (81). pp. 12028-12031. ISSN 1359-7345

Pharmacokinetics

Lappin, G., Boyce, M. J., Matzow, T., Lociuro, S., Seymour, M. and Warrington, S. J. (2013) A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung. European Journal of Clinical Pharmacology, 69 (9). pp. 1673-1682. ISSN 0031-6970

Lappin, Graham (2016) Approaches to intravenous clinical pharmacokinetics: recent developments with isotopic microtracers. The Journal of Clinical Pharmacology, 56 (1). pp. 11-23. ISSN 0091-2700

Lappin, Graham (2011) Microdosing: pharmacokinetic and metabolism data early in the drug development process. In: Pharmacokinetics in drug development: advanves and applications. Pharmacokinetics in Drug Development (3). Springer, New York. ISBN 9781441979377

Lappin, Graham (2010) Pharmacokinetics II: 14C-labelled microdosing in assessing drug pharmacokinetics at phase-0. In: Clinical Pharmacology, Current Topics and Case Studies. Springer, pp. 155-165. ISBN 9783709101438

McLeod, H. L., Brunton, V. G., Eckardt, N., Lear, M. J., Robins, D. J., Workman, P. and Graham, M. A. (1996) In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022. British Journal of Cancer, 74 (11). pp. 1714-1718. ISSN 0007-0920

Pharmacy

Burt, T., Yoshida, K., Lappin, G., Vuong, L., John, C., de Wildt, S. N., Sugiyama, Y. and Rowland, M. (2016) Microdosing and other phase 0 clinical trials: facilitating translation in Drug Development. Clinical and Translational Science, 9 (2). pp. 74-88. ISSN 1752-8054

Lappin, Graham, Tampion, J. and Stride, J. (1989) The biotransformation of monoterpenoids by tissue plant culture. In: Secondary metabolism in plant cell cultures. Cambridge University Press. ISBN UNSPECIFIED

Parmar, Virinder S., Sharma, Nawal K., Husain, Mofazzal, Watterson, Arthur C., Kumar, Jayant, Samuelson, Lynne A., Cholli, Ashok L., Prasad, Ashok K., Kumar, Ajay, Malhotra, Sanjay, Kumar, Naresh, Jha, Amitabh, Singh, Amarjit, Singh, Ishwar, Himanshu, , Vats, Archana, Shakil, Najam A., Trikha, Smriti, Mukherjee, Shubasish, Sharma, Sunil K., Singh, Sanjay K., Kumar, Ajay, Jha, Hriday N., Olsen, Carl E., Stove, Chrisophe P., Bracke, Marc E. and Mareel, Marc M. (2003) Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds. Bioorganic and Medicinal Chemistry, 11 (6). pp. 913-929. ISSN 0968-0896

Raj, Hanumantharao G., Singh, Ishwar, Kohli, Ekta, Kumari, Ranju, Gupta, Garima, Tyagi, Yogesh K., Kumar, Ajit, Prasad, Ashok K., Kaushik, Narendra K., Olsen, Carl E., Watterson, Arthur C. and Parmar, Virinder S. (2003) Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 10: Identification of inhibitors for the liver microsomal acetoxycoumarin: protein transacetylase. Bioorganic and Medicinal Chemistry, 11 (6). pp. 1015-1019. ISSN 0968-0896

Singh, Ishwar, Prasad, Ashok K., Sharma, Ajendra K., Saxena, Rajendra K., Olsen, Carl E., Cholli, Ashok L., Samuelson, Lynne A., Kumar, Jayant, Watterson, Arthur C. and Parmar, Virinder S. (2003) Synthetic and novel biocatalytic resolution studies on (+/-)-5/6/7-acetoxy-4-aryl-3,4-dihydrocoumarins. Bioorganic and Medicinal Chemistry, 11 (4). pp. 529-538. ISSN 0968-0896

Phase 0

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Phase Transition

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Phase transitions, Reaction kinetics

Davey, R. J., Blagden, N., Righini, S., Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

Phase-0

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Phosphodiester

Murphy, Elizabeth J., Bates, Timothy E., Williams, Stephen R., Watson, Tracey, Brindle, Kevin M., Rajagopalan, Bheeshma and Radda, George K. (1992) Endoplasmic reticulum: the major contributor to the PDE peak in hepatic 31P-NMR spectra at low magnetic field strengths. Biochimica et biophysica acta: biomembranes, 1111 (1). pp. 51-58. ISSN 0005-2736

Phosphodiesters

Bates, Timothy E., Williams, Stephen R. and Gadian, David G. (1989) Phosphodiesters in the liver: the effect of field strength on the 31P signal. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 12 (1). pp. 145-150. ISSN 0740-3194

Polymorphic modifications, Carboxylic acids

Davey, R. J., Blagden, N., Righini, S., Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

Polymorphism

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

David, W. I. F., Shankland, K., Pulham, C. R., Blagden, N., Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

Polymorphs

Blagden, Nicholas and Davey, R. (1999) Polymorphs take shape. Chemistry in Britain, 35 (3). pp. 44-45. ISSN 0009-3106

Polystyrene nanoparticles

Moradi, Emilia, Vllasaliu, Driton, Garnett, Martin, Falcone, Franco and Stolnik, Snow (2012) Ligand density and clustering effects on endocytosis of folate modified nanoparticles. RSC Advances, 2 (7). pp. 3025-3033. ISSN 2046-2069

Port

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Prescribing

Laparidou, Despina, Chuter, Antony, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: International Society for Quality in Health Care Conference, 1 - 4 October 2017, London.

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

Primary care

Laparidou, Despina, Chuter, Antony, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: International Society for Quality in Health Care Conference, 1 - 4 October 2017, London.

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

Proliposome

Khan, Iftikhar, Yousaf, Sakib, Subramanian, Sneha, Albed Alhnan, Mohamed, Ahmed, Waqar and Elhissi, Abdelbary (2018) Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: development, characterization and stability evaluation. International Journal of Pharmaceutics . ISSN 0378-5173

Protein microdosing

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Proteins

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Proton

Gadian, D. G., Bates, T. E., Williams, S. R., Bell, J. D., Austin, S. J. and Connelly, A. (1991) Approaches to editing, assignment and interpretation of proton spectra. NMR in biomedicine, 4 (2). pp. 85-89. ISSN 0952-3480

QT prolongation

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Qualitative analysis

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Quality Improvement

Laparidou, Despina, Chuter, Antony, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: International Society for Quality in Health Care Conference, 1 - 4 October 2017, London.

Quality Improvement Collaborative

Laparidou, Despina, Chuter, Antony, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: International Society for Quality in Health Care Conference, 1 - 4 October 2017, London.

Quinine

Osei-Baidoo, Jeremiah S. (2015) The effect of quinine products on tamoxifen resistant breast cancer cells. Masters thesis, University of Lincoln.

RICTOR

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

RNA

Singh, Ishwar, Freeman, Colin, Madder, Annemieke, Vyle, Joseph S. and Heaney, Frances (2012) Fast RNA conjugations on solid phase by strain-promoted cycloadditions. Organic and Biomolecular Chemistry, 10 (33). pp. 6633-6639. ISSN 1477-0520

Raman micro-spectroscopy

Elie, Leonie, Elie, Mathieu, Cave, Gareth, Vetter, Marleen, Croxton, Ruth and Baron, Mark (2016) Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances. Journal of Raman Spectroscopy, 47 (11). pp. 1343-1350. ISSN 0377-0486

Rapamycin

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Rat

van Ravenzwaay, B., Hardwick, T. D., Needham, D., Pethen, S. and Lappin, G. J. (2003) Comparative metabolism of 2,4-dichlorophenoxyacetic acid (2,4-D) in rat and dog. Xenobiotica: the fate of foreign compounds in biological systems, 33 (8). pp. 805-21. ISSN 0049-8254

Redox

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar, Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Reduced toxicity

Casettari, Luca, Vllasaliu, Driton, Mantovani, Guiseppe, Howdle, Steven M., Stolnik, Snow and Illum, Lisbeth (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules, 11 (11). pp. 2854-2865. ISSN 1525-7797

Reperfusion

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Reperfusion injury

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Respiratory Health

Bareham, David, Ahmadi, Keivan, Elie, Mathieu, Jones, Arwel and Mckee, Martin (2018) E-cigarettes: further flavours of controversy within the controversy. Lancet Respiratory Medicine, 6 (1). pp. 16-17. ISSN 2213-2600

Respiratory chain

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Reverse Transcriptase Polymerase Chain Reaction

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

Ribonucleosides

Singh, Ishwar and Heaney, Frances (2010) Metal free, "click and click-click'' conjugation of ribonucleosides and 2'-OMe oligoribonucleotides on the solid phase. Organic and Biomolecular Chemistry, 8 (2). pp. 451-456. ISSN 1477-0520

Ropinirole hydrochloride

Hussein, Nozad, Omer, Huner, Ismael, Ava, Alhnan, Mohamed Albed, Elhissi, Abdelbary and Ahmed, Waqar (2020) Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation. Pharmaceutical Development and Technology, 25 (3). pp. 290-299. ISSN 1083-7450

Run charts

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

SB366791

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

SCN1A

Daci, Armond, Beretta, Giangiacomo, Vllasaliu, Driton, Shala, Aida, Govori, Valbona, Norata, Giuseppe and Krasniqi, Shaip (2015) Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar Albanian epileptic patients. PLOS ONE . ISSN 1932-6203

SFCC

Kulkarni, Chaitrali, Wood, Clive, Kelly, Adrian L., Gough, Tim, Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

SIRT1

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

SMA

Aslam, Adeel, Gajdács, Márió, Zin, Che Suraya, Ab Rahman, Norny Syafinaz, Ahmed, Syed Imran, Zafar, Muhammad Zeeshan and Jamshed, Shazia (2020) Evidence of the Practice of Self-Medication with Antibiotics among the Lay Public in Low- and Middle-Income Countries: A Scoping Review. Antibiotics, 9 (9). p. 597. ISSN 2079-6382

SPAP reporter gene

Abdel-Razaq, W., Bates, T. E. and Kendall, D. A. (2007) The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology, 73 (12). pp. 1995-2003. ISSN 0006-2952

Saccades

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Scattering matrices

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Scattering parameters

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Sensors

Baron, M. G. and Elie, M. (2003) Temperature sensing using reversible thermochromic polymeric films. Sensors and Actuators, B: Chemical, 90 (1-3). pp. 271-275. ISSN 0925-4005

Shear deformation

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Shear rates, Adhesion

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Silylation

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Skeletal Muscle

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Smoking

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

Smoking Cessation

Bareham, David, Ahmadi, Keivan, Elie, Mathieu, Jones, Arwel and Mckee, Martin (2018) E-cigarettes: further flavours of controversy within the controversy. Lancet Respiratory Medicine, 6 (1). pp. 16-17. ISSN 2213-2600

Sodium alginate

Hussein, Nozad, Omer, Huner, Ismael, Ava, Alhnan, Mohamed Albed, Elhissi, Abdelbary and Ahmed, Waqar (2020) Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation. Pharmaceutical Development and Technology, 25 (3). pp. 290-299. ISSN 1083-7450

Solid-phase synthesis

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Solubility

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Solutol® HS15

Shubber, Saif, Vllasaliu, Driton, Rauch, Cyril, Jordan, Faron, Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

Solvents

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Sorbitol

Khan, Iftikhar, Yousaf, Sakib, Subramanian, Sneha, Albed Alhnan, Mohamed, Ahmed, Waqar and Elhissi, Abdelbary (2018) Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: development, characterization and stability evaluation. International Journal of Pharmaceutics . ISSN 0378-5173

Soxhlet extraction

Pavesi, Coralie, Banks, Lucy A. and Hudaib, Taghread (2018) Antifungal and antibacterial activities of eugenol and non-polar extract of Syzygium aromaticum L. Journal of Pharmaceutical Sciences and Research, 10 (2). pp. 337-339. ISSN 0975-1459

Sporidesmin A}

Davis, Carol, Gordon, Natasha, Murphy, Sinead, Singh, Ishwar, Kavanagh, Kevin, Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Spray

Hussein, Nozad, Omer, Huner, Ismael, Ava, Alhnan, Mohamed Albed, Elhissi, Abdelbary and Ahmed, Waqar (2020) Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation. Pharmaceutical Development and Technology, 25 (3). pp. 290-299. ISSN 1083-7450

Staphylococcus aureus

Pavesi, Coralie, Banks, Lucy A. and Hudaib, Taghread (2018) Antifungal and antibacterial activities of eugenol and non-polar extract of Syzygium aromaticum L. Journal of Pharmaceutical Sciences and Research, 10 (2). pp. 337-339. ISSN 0975-1459

Statistical process control charts

Laparidou, Despina, Chuter, Antony, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: International Society for Quality in Health Care Conference, 1 - 4 October 2017, London.

Stevens Johnson syndrome

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Stroke

Asghar, Zahid, Godoy Caballero, Ana Luisa, Pathirannehelage, S., Williams, J., McKay, Steve, Grassby, Paul, de Lusignan, S. and Siriwardena, Niro (2019) Saving bones without risking brain—bisphosphonates and risk of stroke: matched case-control study. Osteoporosis International, 30 (9). pp. 1845-1854. ISSN 0937-941X

Structure elucidation, Organic compounds

David, W. I. F., Shankland, K., Pulham, C. R., Blagden, N., Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

Sulfoxides, Alliaceae

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Sulfur compounds, Polymorphs, Powders, solvent

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

Supersensitivity

Broadley, K. J., Chess-Williams, R. G. and Grassby, P. F. (1986) A physiological basis for subclassifying beta-adrenoceptors examined by chemical sympathectomy of guinea-pigs. Journal of Physiology, 373 (1). pp. 367-378. ISSN 0022-3751

Broadley, K. J., Williams, R. G., Hawthorn, M. H. and Grassby, Paul (1984) Mechanisms of cardiac supersensitivity to sympathomimetic amines. Methods and Findings in Experimental and Clinical Pharmacology, 6 (4). pp. 179-186. ISSN 0379-0355

Supramolecular chemistry, Drug products, er 34122

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Surface modification

Vllasaliu, Driton, Alexander, Cameron, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2012) Fc-mediated transport of nanoparticles across airway epithelial cell layers. Journal of Controlled Release, 158 (3). pp. 479-486. ISSN 0168-3659

Surface plasmon excitation

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Surface plasmon resonance, Plasmons, vinculin, article

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Surfactants

Shubber, Saif, Vllasaliu, Driton, Rauch, Cyril, Jordan, Faron, Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Suspensions

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Synaptosomal

Almeida, A., Brooks, K. J., Sammut, I., Keelan, J., Davey, G. P., Clark, J. B. and Bates, T. E. (1995) Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Developmental Neuroscience, 17 (4). pp. 212-218. ISSN 0378-5866

Bates, T. E, Loesch, A., Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Synaptosomes

Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Synchrotrons

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Synthesis

Kumar, Ajay, Husain, Mofazzal, Prasad, Ashok K., Singh, Iswar, Vats, Archana, Sharma, Nawal K., Sharma, Sunil K., Gupta, Rajinder K., Olsen, Carl E., Bracke, Marc E., Gross, Richard A. and Parmar, Virinder S. (2003) Synthesis of novel heterocyclic compounds: routes to pyrazolyl 1,2,3-triazoles and their biological activity evaluation. Indian Journal of Chemistry : Section B, Oganic Chemistry including Medicinal Chemistry, 42 (8). pp. 1950-1957. ISSN 0376-4699

Lucaioli, Paolo, Nauha, Elisa, Singh, Ishwar and Blagden, Nicholas (2018) First steps for the direct purification of L-Leu-L-Leu dipeptide through co-crystallisation. Crystal Growth & Design, 18 (2). pp. 1062-1069. ISSN 1528-7483

TASTPM

Pardon, Marie-Christine, Sarmad, Sarir, Rattray, Ivan, Bates, Timothy E., Scullion, Gillian A., Marsden, Charles A., Barrett, David A., Lowe, James and Kendall, David A. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging, 30 (7). pp. 1099-1113. ISSN 0197-4580

TBC

Elie, Mathieu Pierre, Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

TEER

Vllasaliu, Driton, Shubber, Saif, Garnett, Martin, Alexander, Cameron, Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

THC

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

TRPV1

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

TSC2

Xie, J., Ponuwei, G.A., Moore, C.E., Willars, G.B., Tee, A.R. and Herbert, Terence (2011) CAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. Cellular Signalling, 23 (12). pp. 1927-1935. ISSN 0898-6568

Tablets

Khan, Iftikhar, Yousaf, Sakib, Subramanian, Sneha, Albed Alhnan, Mohamed, Ahmed, Waqar and Elhissi, Abdelbary (2018) Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: development, characterization and stability evaluation. International Journal of Pharmaceutics . ISSN 0378-5173

Technology, Pharmaceutical

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Temperature

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Temperature measurement, Thermochromic polymeric films, Plastic films

Baron, M. G. and Elie, M. (2003) Temperature sensing using reversible thermochromic polymeric films. Sensors and Actuators, B: Chemical, 90 (1-3). pp. 271-275. ISSN 0925-4005

Tetradecylmaltoside

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Tight junction modulation

Vllasaliu, Driton, Exposito-Harris, Ruth, Heras, Angeles, Casettari, Luca, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Tight junctions

Casettari, Luca, Vllasaliu, Driton, Mantovani, Guiseppe, Howdle, Steven M., Stolnik, Snow and Illum, Lisbeth (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules, 11 (11). pp. 2854-2865. ISSN 1525-7797

Vllasaliu, Driton, Casettari, Luca, Fowler, Robyn, Exposito-Harris, Ruth, Garnett, Martin, Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Vllasaliu, Driton, Fowler, Robyn, Garnett, Martin, Eaton, Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Vllasaliu, Driton, Shubber, Saif, Garnett, Martin, Alexander, Cameron, Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

Time Factors

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Tissue engineering

Casettari, Luca, Vllasaliu, Driton, Lam, Jenny K. W., Soliman, Mahmoud and Illum, Lisbeth (2012) Biomedical applications of amino acid-modified chitosans: a review. Biomaterials, 33 (30). pp. 7565-7583. ISSN 0142-9612

Tissue engineering, Cells

Soon, C. F., Youseffi, M., Blagden, N., Lobo, S. B., Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.

Tobacco

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

Toxicity

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Toxicology

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Transcription

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

Transepithelial electrical resistance

Casettari, Luca, Vllasaliu, Driton, Mantovani, Guiseppe, Howdle, Steven M., Stolnik, Snow and Illum, Lisbeth (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules, 11 (11). pp. 2854-2865. ISSN 1525-7797

Treatment Outcome

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Tridecylmaltoside

Vllasaliu, Driton, Shubber, Saif, Fowler, Robyn, Garnett, Martin, Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Tumors

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Type 2 diabetes mellitus

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2013) Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7 (4). pp. 191-197. ISSN 1871-4021

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2015) Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). International Journal of Diabetes in Developing Countries, 35 (3). pp. 211-218. ISSN 0973-3930

UPR

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

Ultrasensitive drug analysis, Carbon, Animalia

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Unsaturated fatty acid

Perinelli, D. R., Lucarini, S., Fagioli, L., Campana, R., Vllasaliu, D., Duranti, A. and Casettari, L. (2018) Lactose oleate as new biocompatible surfactant for pharmaceutical applications. European Journal of Pharmaceutics and Biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 124 . pp. 55-62. ISSN 0939-6411

Uptake inhibition

Broadley, Kenneth J. and Grassby, Paul F. (1985) Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition. Naunyn-Schmiedeberg's Archives of Pharmacology, 331 (4). pp. 316-323. ISSN 0028-1298

Vaccine delivery

Cole, Hannah (2016) Chitosan-mediated vaccine delivery through the intestinal epithelium. Masters thesis, University of Lincoln.

Van de Graaff accelerators, Accelerator mass spectrometry

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Vanilloid

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

Vanilloids

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

Veterinary Antivirals

Field, Hugh J., Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

Virology

Field, Hugh J., Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

Water

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Watercress

Rose, Peter, Faulkner, Kathy, Williamson, Gary and Mithen, Gary (2000) 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis, 21 (11). pp. 1983-1988. ISSN 0143-3334

Wide-field, Cell adhesion

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Women

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2013) Pregnancy complications, mental health-related problems and type 2 diabetes mellitus in Malaysian women. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 7 (4). pp. 191-197. ISSN 1871-4021

Hasan, Syed Shahzad, Thiruchelvam, Kaeshaelya, Ahmed, Syed Imran, Clavarino, Alexandra M., Mamun, Abdullah A. and Kairuz, Therese (2015) Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). International Journal of Diabetes in Developing Countries, 35 (3). pp. 211-218. ISSN 0973-3930

X ray analysis

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

X ray diffraction, 2-Propanol

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

X ray powder diffraction

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

X ray powder diffraction, Benzamide

David, W. I. F., Shankland, K., Pulham, C. R., Blagden, N., Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

X-ray diffraction

Seaton, Colin C., Blagden, Nicholas, Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

Xanthone

Madan, Babita, Singh, Ishwar, Kumar, Ajit, Prasad, Ashok K., Raj, Hanumantharao G., Parmar, Virinder S. and Ghosh, Balaram (2002) Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs). Bioorganic and Medicinal Chemistry, 10 (11). pp. 3431-3436. ISSN 0968-0896

Y-box protein

Herbert, Terence and Hecht, N.B. (1999) The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs. Nucleic acids research, 27 (7). pp. 1747-1753. ISSN 0305-1048

abasic site

Beuck, C, Singh, I., Bhattacharya, A, Heckler, W, Parmar, VS, Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

absorption enhancers

Shubber, Saif, Vllasaliu, Driton, Rauch, Cyril, Jordan, Faron, Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

acetyl-L-carnitine

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

acne

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

acute liver failure

Bates, T. E., Williams, S. R., Busza, A. L., Gadian, D. G. and Proctor, E. (1988) A 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR in biomedicine, 1 (2). pp. 67-73. ISSN 0952-3480

adult

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

adverse drug reactions

Boateng, Irene, Pascual, Carlos, Asghar, Zahid and Grassby, Paul (2020) The Impact of Poly-Pharmacy on Mortality, Hospitalisation, Adverse Drug Reactions (ADR) and Falls in the Elderly. In: Prescribing and Research in Medicines Management, 15 Jan 2020, University of Manchester.

airway dynamics

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

alliin lyase

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

alpha 1 adrenergic receptor blocking agent

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

amenorrhea

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

ammonia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

amyloid precursor protein

Pardon, Marie-Christine, Sarmad, Sarir, Rattray, Ivan, Bates, Timothy E., Scullion, Gillian A., Marsden, Charles A., Barrett, David A., Lowe, James and Kendall, David A. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging, 30 (7). pp. 1099-1113. ISSN 0197-4580

anandamide

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

anionic host defence peptides.

Harris, Frederick, Prabhu, Saurabh, R. Dennison, Sarah, J. Snape, Timothy, Lea, Robert, Mura, Manuela and A. Phoenix, David (2016) Anionic host defence peptides from the plant kingdom: their anticancer activity and mechanisms of action. Protein & Peptide Letters, 23 (8). pp. 676-687. ISSN 0929-8665

antibiotics

Aslam, Adeel, Gajdács, Márió, Zin, Che Suraya, Ab Rahman, Norny Syafinaz, Ahmed, Syed Imran, Zafar, Muhammad Zeeshan and Jamshed, Shazia (2020) Evidence of the Practice of Self-Medication with Antibiotics among the Lay Public in Low- and Middle-Income Countries: A Scoping Review. Antibiotics, 9 (9). p. 597. ISSN 2079-6382

anticancer

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

Harris, Frederick, Prabhu, Saurabh, R. Dennison, Sarah, J. Snape, Timothy, Lea, Robert, Mura, Manuela and A. Phoenix, David (2016) Anionic host defence peptides from the plant kingdom: their anticancer activity and mechanisms of action. Protein & Peptide Letters, 23 (8). pp. 676-687. ISSN 0929-8665

anticoagulation

Ahmed, Syed Imran and Khan, Shahzad (2020) Coagulopathy and Plausible Benefits of Anticoagulation Among COVID-19 Patients. Current Problems in Cardiology, 45 (9). p. 100648. ISSN 0146-2806

antidepressants

Abdel-Razaq, W., Bates, T. E. and Kendall, D. A. (2007) The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology, 73 (12). pp. 1995-2003. ISSN 0006-2952

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

antiestrogen

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

anxiety disorder

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

apoptosis

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

Herbert, Terence, Fahraeus, R., Prescott, A., Lane, D.P. and Proud, C.G. (2000) Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E. Current Biology, 10 (13). pp. 793-796. ISSN 0960-9822

aqueous solution

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

area under the curve

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

article

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

asthenia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

ataxia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

atenolol

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

bacteriocin

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

beclometasone dipropionate

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

benzodiazepines

Siriwardena, A. Niroshan (2017) Prescribed drug dependence services for long-term BZD use: treating the problem while ignoring its causes. The British Journal of General Practice : the journal of the Royal College of General Practitioners, 67 (664). p. 503. ISSN 0960-1643

beta-adrenoceptors

Broadley, K. J., Chess-Williams, R. G. and Grassby, P. F. (1986) A physiological basis for subclassifying beta-adrenoceptors examined by chemical sympathectomy of guinea-pigs. Journal of Physiology, 373 (1). pp. 367-378. ISSN 0022-3751

bioengineering

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

biological medicines

Alnahar, Saja, Elliott, Rachel A. and Smith, Murray D. (2017) Biosimilar uptake by British local formularies: a cross sectional study. International Journal of Clinical Pharmacy, 39 (5). pp. 1055-1060. ISSN 2210-7703

biosimilars

Alnahar, Saja, Elliott, Rachel A. and Smith, Murray D. (2017) Biosimilar uptake by British local formularies: a cross sectional study. International Journal of Clinical Pharmacy, 39 (5). pp. 1055-1060. ISSN 2210-7703

bipolar I disorder

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

bipolar disorder

Kirkham, Emma, Bazire, Stephen, Anderson, Timothy, Wood, John, Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

blood dyscrasia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

bmjconvert

Perry, Matthew W. D., Björhall, Karin, Bonn, Britta K., Carlsson, Johan, Chen, Yunhua, Eriksson, Anders, Fredlund, Linda, Hao, Hai'e, Holden, Neil S., Karabelas, Kostas, Lindmark, Helena, Liu, Feifei, Pemberton, Nils, Petersen, Jens, Rodrigo Blomqvist, Sandra, Smith, Reed W., Svensson, Tor, Terstiege, Ina, Tyrchan, Christian, Yang, Wenzhen, Zhao, Shuchun and Öster, Linda (2017) Design and synthesis of soluble and cell-permeable PI3Kδ inhibitors for long-acting inhaled administration. Journal of Medicinal Chemistry, 60 (12). pp. 5057-5071. ISSN 0022-2623

bmjdownload

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

bmjindex

Seaton, Colin C., Blagden, Nicholas, Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

brain

Almeida, A., Brooks, K. J., Sammut, I., Keelan, J., Davey, G. P., Clark, J. B. and Bates, T. E. (1995) Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Developmental Neuroscience, 17 (4). pp. 212-218. ISSN 0378-5866

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Bates, T E, Almeida, A, Heales, S J and Clark, J B (1994) Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Developmental neuroscience, 16 (5-6). pp. 321-7. ISSN 0378-5866

brain slices

Brooks, K. J., Kauppinen, R. A., Williams, S. R., Bachelard, H. S., Bates, T. E. and Gadian, D. G. (1989) Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 33 (1). pp. 185-192. ISSN 0306-4522

brain stem

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

budesonide

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

cAMP

Xie, J., Ponuwei, G.A., Moore, C.E., Willars, G.B., Tee, A.R. and Herbert, Terence (2011) CAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. Cellular Signalling, 23 (12). pp. 1927-1935. ISSN 0898-6568

caffeine

Kulkarni, Chaitrali, Wood, Clive, Kelly, Adrian L., Gough, Tim, Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

cancer

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

cannabinoid

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

cannabis, adult

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

capsazepine

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

carbamazepine

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Daci, Armond, Beretta, Giangiacomo, Vllasaliu, Driton, Shala, Aida, Govori, Valbona, Norata, Giuseppe and Krasniqi, Shaip (2015) Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar Albanian epileptic patients. PLOS ONE . ISSN 1932-6203

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

carbon 14

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

carbon tetrachloride

Bates, T. E., Williams, S. R., Busza, A. L., Gadian, D. G. and Proctor, E. (1988) A 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR in biomedicine, 1 (2). pp. 67-73. ISSN 0952-3480

Bates, Timothy E., Williams, Stephen R., Kauppinen, Risto A. and Gadian, David G. (1989) Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of neurochemistry, 53 (1). pp. 102-10. ISSN 0022-3042

case report

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

celiprolol

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

cell adhesion

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

cell interaction

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

cell surface

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

cellular distribution

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

cellular stress

Calabrese, Vittorio, Bates, Timothy E., Mancuso, Cesare, Cornelius, Carolin, Ventimiglia, Bernardo, Cambria, Maria Teresa, Di Renzo, Laura, De Lorenzo, Antonino and Dinkova-Kostova, Albena T. (2008) Curcumin and the cellular stress response in free radical-related diseases. Molecular Nutrition & Food Research, 52 (9). pp. 1062-1073. ISSN 1613-4125

cerebral ischaemia

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

cerebral ischemia

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

chemical modification

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

chemical phenomena

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

chemical reaction

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

chemical structure

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

chemistry

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

child care

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

chitosan

Vllasaliu, Driton, Casettari, Luca, Bonacucina, Giulia, Cespi, Marco, Filippo Palmieri, Giovanni and Illum, Lisbeth (2013) Folic acid conjugated chitosan nanoparticles for tumor targeting of therapeutic and imaging agents. Pharmaceutical Nanotechnology, 1 (3). pp. 184-203. ISSN 2211-7385

chlorimipramine

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

cholesterol

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

clarithromycin

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

clinical article

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

clinical trial

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

clomipramine

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

complex geometry

Sadia, Muzna, Arafat, Basel, Ahmed, Waqar, Forbes, Robert E. and Alhnan, Mohamed A. (2018) Channelled tablets: an innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release, 269 . pp. 355-363. ISSN 0168-3659

complexexs

Almeida, Angeles, Allen, Kathryn L., Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

computer simulation

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

conference paper

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

constipation

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

controlled clinical trial

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

controlled study

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

cornea reflex

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

cost effectiveness analysis

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

cross linking

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

crystal

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

crystal structure

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

crystallization

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

crystallography

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

Davey, R. J., Blagden, N., Potts, G. D. and Docherty, R. (1997) Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. Journal of the American Chemical Society, 119 (7). pp. 1767-1772. ISSN 0002-7863

culture technique

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

curcumin

Calabrese, Vittorio, Bates, Timothy E., Mancuso, Cesare, Cornelius, Carolin, Ventimiglia, Bernardo, Cambria, Maria Teresa, Di Renzo, Laura, De Lorenzo, Antonino and Dinkova-Kostova, Albena T. (2008) Curcumin and the cellular stress response in free radical-related diseases. Molecular Nutrition & Food Research, 52 (9). pp. 1062-1073. ISSN 1613-4125

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

curriculum

Hassali, Mohamed Azmi, Shafie, Asrul Akmal, Awaisu, Ahmed, Mohamed Ibrahim, Mohamed Izham and Ahmed, Syed Imran (2009) A Public Health Pharmacy Course at a Malaysian Pharmacy School. American Journal of Pharmaceutical Education, 73 (7). p. 136. ISSN 0002-9459

cyclic-AMP

Abdel-Razaq, W., Bates, T. E. and Kendall, D. A. (2007) The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology, 73 (12). pp. 1995-2003. ISSN 0006-2952

cysteine

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

cytochrome P450 3A4

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

data analysis

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

data base

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

databases

Kirkham, Emma, Bazire, Stephen, Anderson, Timothy, Wood, John, Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

dementia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

demography

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

development

Almeida, A., Brooks, K. J., Sammut, I., Keelan, J., Davey, G. P., Clark, J. B. and Bates, T. E. (1995) Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Developmental Neuroscience, 17 (4). pp. 212-218. ISSN 0378-5866

Bates, T E, Almeida, A, Heales, S J and Clark, J B (1994) Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Developmental neuroscience, 16 (5-6). pp. 321-7. ISSN 0378-5866

diagnostic and therapeutic imaging

Vllasaliu, Driton, Casettari, Luca, Bonacucina, Giulia, Cespi, Marco, Filippo Palmieri, Giovanni and Illum, Lisbeth (2013) Folic acid conjugated chitosan nanoparticles for tumor targeting of therapeutic and imaging agents. Pharmaceutical Nanotechnology, 1 (3). pp. 184-203. ISSN 2211-7385

diazepam

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

differential scanning calorimetry

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

digoxin

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

diphenhydramine

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

disease association

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

disease course

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

dopamine

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

dopamine receptor

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

dose calculation

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

dose response

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

dose time effect relation

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

drowsiness

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

drug

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

drug absorption

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

drug activity

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

drug and gene delivery

Vllasaliu, Driton, Casettari, Luca, Bonacucina, Giulia, Cespi, Marco, Filippo Palmieri, Giovanni and Illum, Lisbeth (2013) Folic acid conjugated chitosan nanoparticles for tumor targeting of therapeutic and imaging agents. Pharmaceutical Nanotechnology, 1 (3). pp. 184-203. ISSN 2211-7385

drug bioavailability

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug blood level

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

drug classification

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug clearance

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug cost

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

drug delivery system

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

drug derivative

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

drug distribution

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

drug effect

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

drug efficacy

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug eruption

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

drug formulation

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

drug half life

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

drug impurity

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

drug mechanism

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug metabolism

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug microdose

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug monitoring

Kirkham, Emma, Bazire, Stephen, Anderson, Timothy, Wood, John, Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

drug penetration

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

drug research

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

drug retention

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

drug safety

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

drug solubility

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

drug stability

Davey, R. J., Blagden, N., Potts, G. D. and Docherty, R. (1997) Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. Journal of the American Chemical Society, 119 (7). pp. 1767-1772. ISSN 0002-7863

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

drug structure

Davey, R. J., Blagden, N., Potts, G. D. and Docherty, R. (1997) Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. Journal of the American Chemical Society, 119 (7). pp. 1767-1772. ISSN 0002-7863

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

drug withdrawal

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

dyspepsia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

eIF2?

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

eNOS

Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

edema

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

elderly care

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

electron transport chain

Bates, T E, Almeida, A, Heales, S J and Clark, J B (1994) Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Developmental neuroscience, 16 (5-6). pp. 321-7. ISSN 0378-5866

element

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

enalapril

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

endocannabinoid

Pardon, Marie-Christine, Sarmad, Sarir, Rattray, Ivan, Bates, Timothy E., Scullion, Gillian A., Marsden, Charles A., Barrett, David A., Lowe, James and Kendall, David A. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging, 30 (7). pp. 1099-1113. ISSN 0197-4580

endothelial

Kuboki, K., Jiang, Z.Y., Takahara, N., Ha, S.W., Igarashi, M., Yamauchi, T., Feener, E.P., Herbert, Terence, Rhodes, C.J. and King, G.L. (2000) Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo - A specific vascular action of insulin. Circulation, 101 (6). pp. 676-681. ISSN 0009-7322

energy transfer

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

enterocin

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

enzymes

Bates, T E, Almeida, A, Heales, S J and Clark, J B (1994) Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Developmental neuroscience, 16 (5-6). pp. 321-7. ISSN 0378-5866

Beuck, C, Singh, I., Bhattacharya, A, Heckler, W, Parmar, VS, Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

erythrocyte disorder

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

erythromycin

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

excitotoxicity

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

extracellular

Herbert, Terence, Tee, A.R. and Proud, C.G. (2002) The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. Journal of Biological Chemistry, 277 (13). pp. 11591-11596. ISSN 0021-9258

extrapyramidal symptom

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

eye movement control

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

factual

Kirkham, Emma, Bazire, Stephen, Anderson, Timothy, Wood, John, Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

fast GC-MS screening

Elie, Mathieu P., Elie, Leonie E. and Baron, Mark G. (2013) Keeping pace with NPS releases: fast GC-MS screening of legal high products. Drug Testing and Analysis, 5 (5). pp. 281-290. ISSN 1942-7603

feline calicivirus

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1996) Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA. Journal of General Virology, 77 (1). pp. 123-127. ISSN 0022-1317

female

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

fentanyl

Prosser, D., Allman, M. and Grassby, Paul (1998) Oral transmucosal fentanyl. Anaesthesia, 53 (10). p. 1030. ISSN 0003-2409

fermentation

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

fever

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

fexofenadine

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

flow rate

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

fluconazole

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

folic acid

Vllasaliu, Driton, Casettari, Luca, Bonacucina, Giulia, Cespi, Marco, Filippo Palmieri, Giovanni and Illum, Lisbeth (2013) Folic acid conjugated chitosan nanoparticles for tumor targeting of therapeutic and imaging agents. Pharmaceutical Nanotechnology, 1 (3). pp. 184-203. ISSN 2211-7385

food

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

food and drug administration

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

forensic drug analysis

Elie, Mathieu P., Elie, Leonie E. and Baron, Mark G. (2013) Keeping pace with NPS releases: fast GC-MS screening of legal high products. Drug Testing and Analysis, 5 (5). pp. 281-290. ISSN 1942-7603

fosdevirine

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

free radicals

Calabrese, Vittorio, Bates, Timothy E., Mancuso, Cesare, Cornelius, Carolin, Ventimiglia, Bernardo, Cambria, Maria Teresa, Di Renzo, Laura, De Lorenzo, Antonino and Dinkova-Kostova, Albena T. (2008) Curcumin and the cellular stress response in free radical-related diseases. Molecular Nutrition & Food Research, 52 (9). pp. 1062-1073. ISSN 1613-4125

garlic

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

gene expression

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

gene transcription

Abdel-Razaq, W., Bates, T. E. and Kendall, D. A. (2007) The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology, 73 (12). pp. 1995-2003. ISSN 0006-2952

general practice

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

genetics

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

genomic

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1997) Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. Journal of General Virology, 78 (5). pp. 1033-1040. ISSN 0022-1317

glibenclamide

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

glioma

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

glucose

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

glutamate

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

glutamate toxicity

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

glutamic acid, article

Davey, R. J., Blagden, N., Potts, G. D. and Docherty, R. (1997) Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. Journal of the American Chemical Society, 119 (7). pp. 1767-1772. ISSN 0002-7863

glycoprotein P

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

glycosides

Beuck, C, Singh, I., Bhattacharya, A, Heckler, W, Parmar, VS, Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

griseofulvin

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

growth inhibition zone

Pavesi, Coralie, Banks, Lucy A. and Hudaib, Taghread (2018) Antifungal and antibacterial activities of eugenol and non-polar extract of Syzygium aromaticum L. Journal of Pharmaceutical Sciences and Research, 10 (2). pp. 337-339. ISSN 0975-1459

gynecomastia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hair loss

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

half life time

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

haloperidol

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

health care cost

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

health care financing

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

health care utilization

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hearing loss

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hepatitis

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

high performance liquid chromatography

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

hirsutism

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hospitalization

Boateng, Irene, Pascual, Carlos, Asghar, Zahid and Grassby, Paul (2020) The Impact of Poly-Pharmacy on Mortality, Hospitalisation, Adverse Drug Reactions (ADR) and Falls in the Elderly. In: Prescribing and Research in Medicines Management, 15 Jan 2020, University of Manchester.

human

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

human tissue

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

hydration

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

hydrocortisone, article

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

hydrogen bond

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

hydrogen peroxide

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

hydrolysis

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

hydrophilicity

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

hydrophobicity

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

hyperammonemia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hypercholesterolemia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hyperglycemia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hyperprolactinemia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hypertension

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hypertriglyceridemia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

hypothyroidism

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

imaging system

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

immobilized lipas

Plieva, F. M., Kochetkov, K. A., Singh, Ishwar, Parmar, V. S., Belokon', Y. N. and Lozinsky, V. I. (2000) Immobilization of hog pancreas lipase in macroporous poly(vinyl alcohol)-cryogel carrier for the biocatalysis in water-poor media. Biotechnology Letters, 22 (7). pp. 551-554. ISSN 0141-5492

immunocytochemistry

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

immunofluorescence

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

increased appetite

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

influenza

Asghar, Zahid, Coupland, Carol and Siriwardena, Niro (2014) Influenza vaccination and risk of stroke: self-controlled case-series study. In: 42nd North American Primary Care Research Group (NAPCRG) Annual Meeting, 21-25 November 2014, New York.

influenza vaccination

Asghar, Zahid, Coupland, Carol and Siriwardena, Niro (2014) Influenza vaccination and risk of stroke: self-controlled case-series study. In: 42nd North American Primary Care Research Group (NAPCRG) Annual Meeting, 21-25 November 2014, New York.

insulin

Kuboki, K., Jiang, Z.Y., Takahara, N., Ha, S.W., Igarashi, M., Yamauchi, T., Feener, E.P., Herbert, Terence, Rhodes, C.J. and King, G.L. (2000) Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo - A specific vascular action of insulin. Circulation, 101 (6). pp. 676-681. ISSN 0009-7322

interview

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

isobutanol

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

kainate

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

keratinocyte

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

kinetics

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

legal highs

Elie, Mathieu P., Elie, Leonie E. and Baron, Mark G. (2013) Keeping pace with NPS releases: fast GC-MS screening of legal high products. Drug Testing and Analysis, 5 (5). pp. 281-290. ISSN 1942-7603

length of stay

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

leukopenia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

liposome

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

lipoxygenase inhibitor

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

liquid chromatography

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

liquid crystal

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

listeriosis

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

lithium

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Kirkham, Emma, Bazire, Stephen, Anderson, Timothy, Wood, John, Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

liver clearance

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

liver failure

Bates, Timothy E., Williams, Stephen R., Kauppinen, Risto A. and Gadian, David G. (1989) Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of neurochemistry, 53 (1). pp. 102-10. ISSN 0022-3042

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

local formularies

Alnahar, Saja, Elliott, Rachel A. and Smith, Murray D. (2017) Biosimilar uptake by British local formularies: a cross sectional study. International Journal of Clinical Pharmacy, 39 (5). pp. 1055-1060. ISSN 2210-7703

lorazepam

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

losartan

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

low- and middle-income countries

Aslam, Adeel, Gajdács, Márió, Zin, Che Suraya, Ab Rahman, Norny Syafinaz, Ahmed, Syed Imran, Zafar, Muhammad Zeeshan and Jamshed, Shazia (2020) Evidence of the Practice of Self-Medication with Antibiotics among the Lay Public in Low- and Middle-Income Countries: A Scoping Review. Antibiotics, 9 (9). p. 597. ISSN 2079-6382

lung cancer

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

lyase

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

mRNA

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1996) Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA. Journal of General Virology, 77 (1). pp. 123-127. ISSN 0022-1317

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1997) Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. Journal of General Virology, 78 (5). pp. 1033-1040. ISSN 0022-1317

Herbert, Terence and Hecht, N.B. (1999) The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs. Nucleic acids research, 27 (7). pp. 1747-1753. ISSN 0305-1048

mTOR

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

mTORC1

Johnson, C. E., Hunt, D. K., Wiltshire, M., Herbert, T. P., Sampson, J. R., Errington, R. J., Davies, D. M. and Tee, A. R. (2015) Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine. Molecular Oncology, 9 (3). pp. 675-688. ISSN 1574-7891

Xie, J., Ponuwei, G.A., Moore, C.E., Willars, G.B., Tee, A.R. and Herbert, Terence (2011) CAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. Cellular Signalling, 23 (12). pp. 1927-1935. ISSN 0898-6568

mTORC2

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Xie, J., Ponuwei, G.A., Moore, C.E., Willars, G.B., Tee, A.R. and Herbert, Terence (2011) CAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. Cellular Signalling, 23 (12). pp. 1927-1935. ISSN 0898-6568

male

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

maleic acid

Kulkarni, Chaitrali, Wood, Clive, Kelly, Adrian L., Gough, Tim, Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

manganese [III] tetrakis 4-benzoic acid porphyrin

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

mania

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

mass spectrometry

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

material coating

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

measurement accuracy

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

medical decision making

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

medical literature

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

medical nebulizer

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

menstrual irregularity

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

mental health service

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

metabolism

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

metformin

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

methanol

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

methodology

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

metoprolol

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

microdosing

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

microfluidic nanoprecipitation

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

microfluidics

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

microscopy

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

midazolam

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

mitochondria

Almeida, A., Brooks, K. J., Sammut, I., Keelan, J., Davey, G. P., Clark, J. B. and Bates, T. E. (1995) Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Developmental Neuroscience, 17 (4). pp. 212-218. ISSN 0378-5866

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

Bates, T E, Almeida, A, Heales, S J and Clark, J B (1994) Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Developmental neuroscience, 16 (5-6). pp. 321-7. ISSN 0378-5866

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

mitochondrial complexes

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

mitochondrial membrane potential

Athanasiou, Andriani, Clarke, Anna B., Turner, Amy E., Kumaran, Nethia M., Vakilpour, Sara, Smith, Paul A., Bagiokou, Dimitra, Bradshaw, Tracey D., Westwell, Andrew D., Fang, Lin, Lobo, Dileep N., Constantinescu, Cris S., Calabrese, Vittorio, Loesch, Andrzej, Alexander, Stephen P. H., Clothier, Richard H., Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

molecular interaction

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

molecular model

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

molecular stability

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

monitoring

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

multiple sclerosis

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

myalgia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

nanodispersion formulation

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

nanoparticle

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

national health service

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

nausea

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

nebulization

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

necrosis

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

neurodegeneration

Calabrese, Vittorio, Cornelius, Carolin, Mancuso, Cesare, Pennisi, Giovanni, Calafato, Stella, Bellia, Francesco, Bates, Timothy E., Giuffrida Stella, Anna Maria, Schapira, Tony, Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

neuroprotection

Calabrese, Vittorio, Cornelius, Carolin, Mancuso, Cesare, Pennisi, Giovanni, Calafato, Stella, Bellia, Francesco, Bates, Timothy E., Giuffrida Stella, Anna Maria, Schapira, Tony, Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

nicardipine

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

nitromethane

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

nonhuman

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

normal human

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

novel psychoactive substances

Elie, Mathieu P., Elie, Leonie E. and Baron, Mark G. (2013) Keeping pace with NPS releases: fast GC-MS screening of legal high products. Drug Testing and Analysis, 5 (5). pp. 281-290. ISSN 1942-7603

nucleic acids}

Beuck, C, Singh, I., Bhattacharya, A, Heckler, W, Parmar, VS, Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

nutrition

Calabrese, Vittorio, Cornelius, Carolin, Mancuso, Cesare, Pennisi, Giovanni, Calafato, Stella, Bellia, Francesco, Bates, Timothy E., Giuffrida Stella, Anna Maria, Schapira, Tony, Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

nystagmus

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

oadoaj

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

oaemailed

Garnett, Martin, Vllasaliu, Driton, Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

olanzapine

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

oligodendrocyte

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

optical density

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

optical reflection

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

otalgia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

oxidative stress

Bates, T. E., Heales, S. J., Davies, S. E., Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Rosin, Claudia, Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

pH effects

Baron, M. G. and Elie, M. (2003) Temperature sensing using reversible thermochromic polymeric films. Sensors and Actuators, B: Chemical, 90 (1-3). pp. 271-275. ISSN 0925-4005

pancytopenia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

paracetamol

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

parkinsonism

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

particle size

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

patient compliance

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

patient participation

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

peer review

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

peptides

Herbert, Terence, Fahraeus, R., Prescott, A., Lane, D.P. and Proud, C.G. (2000) Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E. Current Biology, 10 (13). pp. 793-796. ISSN 0960-9822

peroxynitrite

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

personalised

Sadia, Muzna, Arafat, Basel, Ahmed, Waqar, Forbes, Robert E. and Alhnan, Mohamed A. (2018) Channelled tablets: an innovative approach to accelerating drug release from 3D printed tablets. Journal of Controlled Release, 269 . pp. 355-363. ISSN 0168-3659

pharmacy

Singh, Ishwar, Kohli, E., Raj, H. G., Gyanda, K., Jain, S. K., Tyagi, Y. K., Gupta, G., Kumari, R., Kumar, A., Pal, G., Prasad, A. K., Rastogi, R. C., Olsen, C. E., Jain, S. C. and Parmar, V. S. (2002) Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 9: comparison of acetoxy 4-methylcoumarins and other polyphenolic acetates reveal the specificity to acetoxy drug: protein transacetylase for pyran carbonyl group in proximity to the oxygen heteroatom. Bioorganic and Medicinal Chemistry, 10 (12). pp. 4103-4111. ISSN 0968-0896

phase transition

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

phenazone

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

phenobarbital

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

phospholipid

Murphy, Elizabeth J., Bates, Timothy E., Williams, Stephen R., Watson, Tracey, Brindle, Kevin M., Rajagopalan, Bheeshma and Radda, George K. (1992) Endoplasmic reticulum: the major contributor to the PDE peak in hepatic 31P-NMR spectra at low magnetic field strengths. Biochimica et biophysica acta: biomembranes, 1111 (1). pp. 51-58. ISSN 0005-2736

phospholipid vesicle

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

phosphorylation

Herbert, Terence, Tee, A.R. and Proud, C.G. (2002) The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. Journal of Biological Chemistry, 277 (13). pp. 11591-11596. ISSN 0021-9258

photon correlation spectroscopy

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

photosensitivity

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

physical chemistry

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

piracetam

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

placebo

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

plasma concentration-time curve

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

poly(vinyl alcohol)-cryogel carrier}

Plieva, F. M., Kochetkov, K. A., Singh, Ishwar, Parmar, V. S., Belokon', Y. N. and Lozinsky, V. I. (2000) Immobilization of hog pancreas lipase in macroporous poly(vinyl alcohol)-cryogel carrier for the biocatalysis in water-poor media. Biotechnology Letters, 22 (7). pp. 551-554. ISSN 0141-5492

poly-pharmacy

Boateng, Irene, Pascual, Carlos, Asghar, Zahid and Grassby, Paul (2020) The Impact of Poly-Pharmacy on Mortality, Hospitalisation, Adverse Drug Reactions (ADR) and Falls in the Elderly. In: Prescribing and Research in Medicines Management, 15 Jan 2020, University of Manchester.

polycarbonate

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

polydispersity index

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

polysorbate 80

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

positron emission tomography

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

precipitation

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

prediction

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

presenilin-1

Pardon, Marie-Christine, Sarmad, Sarir, Rattray, Ivan, Bates, Timothy E., Scullion, Gillian A., Marsden, Charles A., Barrett, David A., Lowe, James and Kendall, David A. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging, 30 (7). pp. 1099-1113. ISSN 0197-4580

priapism

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

priority journal

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

priority journal, Administration, Oral

Lappin, Graham, Kuhnz, Wilhelm, Jochemsen, Roeline, Kneer, Johannes, Chaudhary, Ajai, Oosterhuis, Berend, Drijfhout, Willem Jan, Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

probability

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

prolactin

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

propafenone

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

prostaglandin synthase inhibitor

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

protein

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1997) Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. Journal of General Virology, 78 (5). pp. 1033-1040. ISSN 0022-1317

protein kinase

Gomez, E., Pritchard, C. and Herbert, Terence (2002) cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic β-cells. Journal of Biological Chemistry, 277 (50). pp. 48146-48151. ISSN 0021-9258

protein polymorphism

Davey, R. J., Blagden, N., Potts, G. D. and Docherty, R. (1997) Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. Journal of the American Chemical Society, 119 (7). pp. 1767-1772. ISSN 0002-7863

psychiatry

Kirkham, Emma, Bazire, Stephen, Anderson, Timothy, Wood, John, Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

psychologic assessment

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

public health

Hassali, Mohamed Azmi, Shafie, Asrul Akmal, Awaisu, Ahmed, Mohamed Ibrahim, Mohamed Izham and Ahmed, Syed Imran (2009) A Public Health Pharmacy Course at a Malaysian Pharmacy School. American Journal of Pharmaceutical Education, 73 (7). p. 136. ISSN 0002-9459

pulmicort respule

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

quality control

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

quality improvement

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

quality of life

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

quetiapine

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

quinidine

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

raltegravir

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

randomized controlled trial

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

rating scale

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

reactor

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

redox homeostasis

Calabrese, Vittorio, Cornelius, Carolin, Mancuso, Cesare, Pennisi, Giovanni, Calafato, Stella, Bellia, Francesco, Bates, Timothy E., Giuffrida Stella, Anna Maria, Schapira, Tony, Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

redox state

Calabrese, Vittorio, Cornelius, Carolin, Mancuso, Cesare, Pennisi, Giovanni, Calafato, Stella, Bellia, Francesco, Bates, Timothy E., Giuffrida Stella, Anna Maria, Schapira, Tony, Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

redox-dependent

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

reduction

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

refraction index

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

resiniferatoxin

Athanasiou, Andriani, Smith, Paul A., Vakilpour, Sara, Kumaran, Nethia M., Turner, Amy E., Bagiokou, Dimitra, Layfield, Robert, Ray, David E., Westwell, Andrew D., Alexander, Stephen P. H., Kendall, David A., Lobo, Dileep N., Watson, Susan A., Lophatanon, Artitaya, Muir, Kenneth A., Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

respiratory chain complexes

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

resveratrol

Mancuso, Cesare, Bates, Timothy E., Butterfield, D. Allan, Calafato, Stella, Cornelius, Carolin, De Lorenzo, Antonino, Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

reverse transcription polymerase chain reaction

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

review

Aslam, Adeel, Gajdács, Márió, Zin, Che Suraya, Ab Rahman, Norny Syafinaz, Ahmed, Syed Imran, Zafar, Muhammad Zeeshan and Jamshed, Shazia (2020) Evidence of the Practice of Self-Medication with Antibiotics among the Lay Public in Low- and Middle-Income Countries: A Scoping Review. Antibiotics, 9 (9). p. 597. ISSN 2079-6382

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

review, Allium

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

review, Biological Availability

Blagden, N., de Matas, M., Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

rhinitis

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

saccadic eye movement

Golding, C. V. P., Danchaivijitr, C., Hodgson, T. L., Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

salbutamol sulfate, aerosol

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

scanning electron microscopy

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

scanning transmission electron microscopy

Amani, Amir, Ali, Hany, Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

schizophrenia

Rosin, Claudia, Colombo, Sergio, Calver, Andrew A., Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

scoping

Aslam, Adeel, Gajdács, Márió, Zin, Che Suraya, Ab Rahman, Norny Syafinaz, Ahmed, Syed Imran, Zafar, Muhammad Zeeshan and Jamshed, Shazia (2020) Evidence of the Practice of Self-Medication with Antibiotics among the Lay Public in Low- and Middle-Income Countries: A Scoping Review. Antibiotics, 9 (9). p. 597. ISSN 2079-6382

self-controlled case-series method

Asghar, Zahid, Coupland, Carol and Siriwardena, Niro (2014) Influenza vaccination and risk of stroke: self-controlled case-series study. In: 42nd North American Primary Care Research Group (NAPCRG) Annual Meeting, 21-25 November 2014, New York.

self-medication

Aslam, Adeel, Gajdács, Márió, Zin, Che Suraya, Ab Rahman, Norny Syafinaz, Ahmed, Syed Imran, Zafar, Muhammad Zeeshan and Jamshed, Shazia (2020) Evidence of the Practice of Self-Medication with Antibiotics among the Lay Public in Low- and Middle-Income Countries: A Scoping Review. Antibiotics, 9 (9). p. 597. ISSN 2079-6382

sensitivity analysis

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

siRNA

Zhang, Mengtian, Wang, Qin, Wan, Ka-Wai, Ahmed, Waqar, Phoenix, David, Zhang, Zhirong, Elrayess, Mohamed A, Elhissi, Abdelbary and Sun, Xun (2019) Liposome Mediated-CYP1A1 Gene Silencing Nanomedicine Prepared Using Lipid Film-Coated Proliposomes as a Potential Treatment Strategy of Lung Cancer. International Journal of Pharmaceutics, 566 . pp. 185-193. ISSN 0378-5173

siRNA delivery

Capel, Victoria, Vllasaliu, Driton, Watts, Peter and Stolnik, Snow (2016) Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency. Biochemical and Biophysical Research Communications, 477 (2). pp. 260-265. ISSN 0006-291X

side effect

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

simulation

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

single nucleotide polymorphism

Daci, Armond, Beretta, Giangiacomo, Vllasaliu, Driton, Shala, Aida, Govori, Valbona, Norata, Giuseppe and Krasniqi, Shaip (2015) Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar Albanian epileptic patients. PLOS ONE . ISSN 1932-6203

smoking

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

solid phase extraction

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

solid state

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

solvation

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

solvent

Blagden, Nicholas, Cross, Wendy I., Davey, Roger J., Broderick, Mairead, Pritchard, Robin G., Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

solvent effect

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

solvent, chemical engineering

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

somnolence

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

soybean

Subramanian, S., Khan, I., Korale, O., Alhnan, M. A., Ahmed, W., Najlah, M., Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

spectral editing

Gadian, D. G., Bates, T. E., Williams, S. R., Bell, J. D., Austin, S. J. and Connelly, A. (1991) Approaches to editing, assignment and interpretation of proton spectra. NMR in biomedicine, 4 (2). pp. 85-89. ISSN 0952-3480

speech disorder

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

statistical analysis

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

statistical process control

Laparidou, Despina, Panayiotidis, Tony, Rodgers, Sarah, Avery, Tony, Wiseman, Janice, Rye, Chris, Bowler, Susan, Waring, Justin, Armstrong, Sarah, Mehta, Raj, Salema, Ndeshi, Bell, Brian, Ashcroft, Darren, Elliott, Rachel, Sheikh, Aziz, Chuter, Antony, Swanwick, Glen, Boyd, Matthew, Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

stoichiometry

Kulkarni, Chaitrali, Wood, Clive, Kelly, Adrian L., Gough, Tim, Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

stomach disease

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

stroke

Asghar, Zahid, Coupland, Carol and Siriwardena, Niro (2014) Influenza vaccination and risk of stroke: self-controlled case-series study. In: 42nd North American Primary Care Research Group (NAPCRG) Annual Meeting, 21-25 November 2014, New York.

sub-classification

Broadley, K. J., Chess-Williams, R. G. and Grassby, P. F. (1986) A physiological basis for subclassifying beta-adrenoceptors examined by chemical sympathectomy of guinea-pigs. Journal of Physiology, 373 (1). pp. 367-378. ISSN 0022-3751

subgenomic

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1997) Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. Journal of General Virology, 78 (5). pp. 1033-1040. ISSN 0022-1317

sugar-based surfactants

Lucarini, Simone, Fagioli, Laura, Campana, Raffaella, Cole, Hannah, Duranti, Andrea, Baffone, Wally, Vllasaliu, Driton and Casettari, Luca (2016) Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity. European Journal of Pharmaceutics and Biopharmaceutics, 107 . pp. 88-96. ISSN 0939-6411

sulfathiazole, aqueous solution

Blagden, N., Davey, R. J., Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

sulfathiazole, crystal

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

sulfoxide, catalysis

Rose, Peter, Whiteman, Matt, Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

sumatriptan

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

superoxide dismutase

Brooks, Keith J., Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

surface property

Soon, Chin Phong, Khaghani, Seyed Ali, Youseffi, Mansour, Nayan, Nafarizal, Saim, Hashim, Britland, Stephen, Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

suspension

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

symptom

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

tachycardia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

tandem mass spectrometry

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

tegmentum, Eye Movements

Schon, F., Hart, P. E., Hodgson, T. L., Pambakian, A. L. M., Ruprah, M., Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

telmisartan

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

temperature sensitivity

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

tenofovir

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

thermodynamics

Dematos, Luciana L., Williams, Adrian C., Booth, Steven W., Petts, Catherine R., Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

thrombocyte aggregation inhibition

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

thrombocytopenia

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

thyroid hormone

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

tolbutamide

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham, Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

toxic epidermal necrolysis

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

toxicology

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

transmission electron microscopy

Ali, Hany S. M., York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

transmucosal

Prosser, D., Allman, M. and Grassby, Paul (1998) Oral transmucosal fentanyl. Anaesthesia, 53 (10). p. 1030. ISSN 0003-2409

treatment outcome

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

tremor

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

triacylglycerol

Bridle, C., Palmer, S., Bagnall, A.-M., Darba, J., Duffy, S., Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

tricyclic

Daley, E., Wilkie, D., Loesch, A., Hargreaves, I. P., Kendall, D. A., Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Resea