2020

Aksentijevic, Dunja, Karlstaedt, Anja, Basalay, Marina, O'Brien, Brett, Sanchez-Tatay, David, Eminaga, Seda, Thakker, Alpesh, Tennant, Daniel, Fuller, William, Eykyn, Thomas, Taegtmeyer, Heinrich and Shattock, Michael (2020) Intracellular sodium elevation reprograms cardiac metabolism. Nature Communications, 11 (1). ISSN 2041-1723

Routledge, Sarah J., Jamshad, Mohammed, Little, Haydn A., Lin, Yu-Pin, Simms, John, Thakker, Alpesh, Spickett, Corinne M., Bill, Roslyn M., Dafforn, Tim R., Poyner, David R. and Wheatley, Mark (2020) Ligand-induced conformational changes in a SMALP-encapsulated GPCR. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862 (6). p. 183235.

Sinton, Matthew C., Lucendo Villarin, Baltasar, Meseguer Ripolles, Jose, Wernig-Zorc, Sara, Thomson, John P., Walker, Paul D., Thakker, Alpesh, Lavery, Gareth G., Ludwig, Christian, Tennant, Daniel A., Hay, David C. and Drake, Amanda J. (2020) Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of purine nucleotide cycle driven fumarate accumulation.

Kľučková, Katarína, Thakker, Alpesh, Vettore, Lisa, Escribano-Gonzalez, Cristina, Hindshaw, Rebecca L., Tearle, Jacqueline L. E., Goncalves, Judith, Kaul, Baksho, Lavery, Gareth G., Favier, Judith and Tennant, Daniel A. (2020) Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function. The FASEB Journal, 34 (1). pp. 303-315.

Nasteska, Daniela, Cuozzo, Federica, Thakker, Alpesh, Bakar, Rula Bany, Westbrook, Rebecca, Akerman, Ildem, Cantley, James, Tennant, Daniel A. and Hodson, David J. (2020) The prolyl hydroxylase PHD3 maintains β-cell glucose metabolism during fatty acid excess.

2019

Teo, Alvin C. K., Lee, Sarah C., Pollock, Naomi L., Stroud, Zoe, Hall, Stephen, Thakker, Alpesh, Pitt, Andrew R., Dafforn, Timothy R., Spickett, Corinne M. and Roper, David I. (2019) Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein. Scientific Reports, 9 (1).

Patel, Kamlesh, Smith, Thomas B., Neil, Desley A.H., Thakker, Alpesh, Tsuchiya, Yugo, Higgs, Ellen B., Hodges, Nikolas J., Ready, Andrew R., Nath, Jay and Ludwig, Christian (2019) The Effects of Oxygenation on Ex Vivo Kidneys Undergoing Hypothermic Machine Perfusion. Transplantation, 103 (2). pp. 314-322.

Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian and Lavery, Gareth G. (2019) Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion. Wellcome Open Research, 3 . p. 147.

Thakker, Alpesh, Daniela, Nateska and Federica, Cuozzo (2019) Prolyl-hydroxylase 3 regulates β-cell phenotype under obesogenic conditions. In: UNSPECIFIED.

Thakker, Alpesh, Pitt, Andrew and Spickett, Corinne (2019) Serial coupling of chromatographic columns having orthogonal selectivity to improve the coverage of oxidised lipidome for mass spectrometry analysis.

Thakker, Alpesh, Spickett, Corinne M and Pitt, Andrew (2019) A Targeted Mass Spectrometry Approach to detect and quantify Oxidised Phospholipids in plasma samples of Diabetic patients.

2018

Hollinshead, Kate, Munford, Haydn, Eales, Katherine, Gonzalez, Cristina Escribano, Thakker, Alpesh, Cuozzo, Federica, Murren, Robert, Ludwig, Christian and Tennant, Daniel (2018) IDH1 mutations drive an oxygen-sparing metabolic phenotype to permit tumour growth. Neuro-Oncology, 20 (1). i4-i4.

Oakey, Lucy A., Fletcher, Rachel S., Elhassan, Yasir S., Cartwright, David M., Doig, Craig L., Garten, Antje, Thakker, Alpesh, Maddocks, Oliver D. K., Zhang, Tong, Tennant, Daniel A., Ludwig, Christian and Lavery, Gareth G. (2018) Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion. Wellcome Open Research, 3 . p. 147.

Hollinshead, Kate E.R., Munford, Haydn, Eales, Katherine L., Bardella, Chiara, Li, Chunjie, Escribano-Gonzalez, Cristina, Thakker, Alpesh, Nonnenmacher, Yannic, Kluckova, Katarina, Jeeves, Mark, Murren, Robert, Cuozzo, Federica, Ye, Dan, Laurenti, Giulio, Zhu, Wei, Hiller, Karsten, Hodson, David J., Hua, Wei, Tomlinson, Ian P., Ludwig, Christian, Mao, Ying and Tennant, Daniel A. (2018) Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis. Cell Reports, 22 (12). pp. 3107-3114.

2017

Popat, Reena J., Hakki, Seran, Thakker, Alpesh, Coughlan, Alice M., Watson, Julie, Little, Mark A., Spickett, Corinne M., Lavender, Paul, Afzali, Behdad, Kemper, Claudia and Robson, Michael G. (2017) Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development. JCI Insight, 2 (2).

Popat, Reena J., Hakki, Seran, Thakker, Alpesh, Coughlan, Alice M., Watson, Julie, Little, Mark A., Spickett, Corinne M., Lavender, Paul, Afzali, Behdad, Kemper, Claudia and Robson, Michael G. (2017) Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development. JCI Insight, 2 (2).

Thakker, Alpesh (2017) Development of mass spectrometry protocols to study oxidised lipidome in inflammatory disease models. PhD thesis, UNSPECIFIED.

2015

Thakker, Alpesh, Spickett, Corinne and Pitt, Andrew (2015) Optimisation of chromatographic separation of oxidised phospholipids and detection with targeted approaches provides greater coverage of the oxidised lipidome. Free Radical Biology and Medicine, 86 (1). S25.

2014

Robaszkiewicz, Agnieszka, Bartosz, Grzegorz, Pitt, Andrew R., Thakker, Alpesh, Armstrong, Richard A., Spickett, Corinne M. and Soszyński, Mirosław (2014) HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells. Archives of Biochemistry and Biophysics, 548 . pp. 1-10.