Article

Herbert, Terence, Yeh, Siang Lau, Mohd, Rais Mustafa, Ker, Woon Choy, Stanley, M. H. Chan, Simon, Potocnik and Owen, L. Woodman (2018) 3′,4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice. Scientific Reports, 8 (1). p. 1818. ISSN 2045-2322

Chan, Stanley M. H., Lowe, Mark P., Bernard, Ashton, Miller, Alyson A. and Herbert, Terence P. (2018) The inositol requiring enzyme 1 (IRE1α) RNAse inhibitor, 4µ8C, is also a potent cellular antioxidant. Biochemical Journal, 475 (5). pp. 923-929. ISSN 0264-6021

Chan, S. M. H., Lau, Y.-S., Miller, A. A., Ku, J. M., Potocnik, S., Ye, J.-M., Woodman, O. L. and Herbert, T. P. (2017) Angiotensin II causes b-cell dysfunction through an ER stress-induced proinflammatory response. Endocrinology, 158 (10). pp. 3162-3173. ISSN 0013-7227

Chan, S. M. H., Zhao, X., Elfowiris, A., Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

Jo, E., Li, S., Liang, Q., Zhang, X., Wang, H., Herbert, T.P., Jenkins, T. A., Xu, A. and Ye, J.-M. (2017) Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21. PLoS ONE, 12 (4). e0173676. ISSN 1932-6203

Wang, H., Sun, R.-Q., Camera, D., Zeng, X.-Y., Jo, E., Chan, S. M. H., Herbert, T. P., Molero, J. C. and Ye, J.-M. (2016) Endoplasmic reticulum stress up-regulates Nedd4-2 to induce autophagy. The FASEB Journal, 30 (7). pp. 2549-2556. ISSN 0892-6638

Herbert, T. P. and Laybutt, D. R. (2016) A reevaluation of the role of the unfolded protein response in islet dysfunction: maladaptation or a failure to adapt? Diabetes, 65 (6). pp. 1472-1480. ISSN 0012-1797

Cheng, Q., Beltran, V. D., Chan, S. M. H., Brown, J. R., Bevington, A. and Herbert, T. P. (2016) System-L amino acid transporters play a key role in pancreatic b-cell signalling and function. Journal of Molecular Endocrinology, 56 (3). pp. 175-187. ISSN 0952-5041

Johnson, C. E., Hunt, D. K., Wiltshire, M., Herbert, T. P., Sampson, J. R., Errington, R. J., Davies, D. M. and Tee, A. R. (2015) Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine. Molecular Oncology, 9 (3). pp. 675-688. ISSN 1574-7891

Xie, J., El Sayed, N. M., Qi, C., Zhao, X., Moore, C. E. and Herbert, T. P. (2014) Exendin-4 stimulates islet cell replication via the IGF1 receptor activation of mTORC1/s6k1. Journal of Molecular Endocrinology, 53 (1). pp. 105-115. ISSN 0952-5041

Chen, C., Cano, M., Wang, J. J., Li, J., Huang, C., Yu, Q., Herbert, T. P., Handa, J. T. and Zhang, S. X. (2014) Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells. Antioxidants & Redox Signaling, 20 (14). pp. 2091-2106. ISSN 1523-0864

Barlow, A. D., Nicholson, M. L. and Herbert, T. P. (2013) Evidence for rapamycin toxicity in pancreatic b-Cells and a review of the underlying molecular mechanisms. Diabetes, 62 (8). pp. 2674-2682. ISSN 0012-1797

Selway, J. L., Moore, C. E., Mistry, R., Challiss, R. A. J. and Herbert, T. P. (2012) Molecular mechanisms of muscarinic acetylcholine receptor-stimulated increase in cytosolic free Ca2+ concentration and ERK1/2 activation in the MIN6 pancreatic b-cell line. Acta Diabetologica, 49 (4). pp. 277-289. ISSN 0940-5429

Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Selway, J., Rigatti, R., Storey, N., Lu, J., Willars, G. B. and Herbert, T. P. (2012) Evidence that Ca 2+ within the microdomain of the l-type voltage gated Ca 2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1. PLoS ONE, 7 (3). 0033004. ISSN 1932-6203

Xie, J., Ponuwei, G.A., Moore, C.E., Willars, G.B., Tee, A.R. and Herbert, Terence (2011) CAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. Cellular Signalling, 23 (12). pp. 1927-1935. ISSN 0898-6568

Gomez, E., Powell, M.L., Bevington, A. and Herbert, T. P. (2008) A decrease in cellular energy status stimulates PERK-dependent eIF2α phosphorylation and regulates protein synthesis in pancreatic β-cells. Biochemical Journal, 410 (3). pp. 485-493. ISSN 0264-6021

Greenman, I.C., Gomez, E., Moore, C.E.J. and Herbert, Terence (2007) Distinct glucose-dependent stress responses revealed by translational profiling in pancreatic β-cells. Journal of Endocrinology, 192 (1). pp. 179-187. ISSN 0022-0795

Greenman, I. C., Gomez, E., Moore, C. E. J. and Herbert, T. P. (2005) The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic β-cells. Biochemical Journal, 391 (2). pp. 291-300. ISSN 0264-6021

Gomez, E., Powell, M.L., Greenman, I.C. and Herbert, Terence (2004) Glucose-stimulated protein synthesis in pancreatic β-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP-Met-tRNAi) and the dephosphorylation of eIF2α. Journal of Biological Chemistry, 279 (52). pp. 53937-53946. ISSN 0021-9258

Gomez, E., Pritchard, C. and Herbert, Terence (2002) cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic β-cells. Journal of Biological Chemistry, 277 (50). pp. 48146-48151. ISSN 0021-9258

Herbert, Terence, Tee, A.R. and Proud, C.G. (2002) The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. Journal of Biological Chemistry, 277 (13). pp. 11591-11596. ISSN 0021-9258

Wicksteed, B., Herbert, T. P., Alarcon, C., Lingohr, M. K., Moss, L. G. and Rhodes, C. J. (2001) Cooperativity between the preproinsulin mRNA untranslated regions Is necessary for glucose-stimulated translation. Journal of Biological Chemistry, 276 (25). pp. 22553-22558. ISSN 0021-9258

Herbert, T. P., Kilhams, G. R., Batty, I. H. and Proud, C. G. (2000) Distinct signalling pathways mediate insulin and phorbol ester- stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells. Journal of Biological Chemistry, 275 (15). pp. 11249-11256. ISSN 0021-9258

Herbert, Terence, Fahraeus, R., Prescott, A., Lane, D.P. and Proud, C.G. (2000) Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E. Current Biology, 10 (13). pp. 793-796. ISSN 0960-9822

Kuboki, K., Jiang, Z.Y., Takahara, N., Ha, S.W., Igarashi, M., Yamauchi, T., Feener, E.P., Herbert, Terence, Rhodes, C.J. and King, G.L. (2000) Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo - A specific vascular action of insulin. Circulation, 101 (6). pp. 676-681. ISSN 0009-7322

Herbert, Terence and Hecht, N.B. (1999) The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs. Nucleic acids research, 27 (7). pp. 1747-1753. ISSN 0305-1048

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1997) Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. Journal of General Virology, 78 (5). pp. 1033-1040. ISSN 0022-1317

Herbert, Terence, Brierley, I. and Brown, T.D.K. (1996) Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA. Journal of General Virology, 77 (1). pp. 123-127. ISSN 0022-1317

Conference or Workshop contribution

Herbert, Terence and Wardman, Rhys (2019) 'The global identification of glucose-regulated RNA binding proteins (RBPs) in pancreatic β-cells reveals a link between insulin secretion and gene expression.'. In: Translation UK 2019, 3-5 July 2019, Strathclyde Business School, Glasgow.