Polymorph selection: challenges for the future?

Blagden, Nicholas and Davey, R. J. (2003) Polymorph selection: challenges for the future? Crystal Growth and Design, 3 (6). pp. 873-885. ISSN 1528-7483

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Item Type:Article
Item Status:Live Archive


This contribution reviews the area of polymorph selection during solution crystallization using known and predicted structures. In particular, an overview of what has been learned about the relationship between structure and kinetics and of the interplay between thermodynamics and kinetics is presented. This review adds to the debate by discussing the future challenges that we envisage in realizing polymorph selection as a crystal engineering exercise by highlighting the role that a packing landscape approach may contribute in manipulating the selection of a polymorph.

Keywords:conference paper, crystal, crystal structure, crystallization, kinetics, thermodynamics
Subjects:B Subjects allied to Medicine > B230 Pharmacy
F Physical Sciences > F100 Chemistry
Divisions:College of Science > School of Pharmacy
ID Code:8770
Deposited On:04 Apr 2013 11:26

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