Blagden, Nicholas, Berry, David J., Parkin, Aandrew , Javed, Hafsa, Ibrahim, Asim, Gavan, Pauline T., De Matos, Luciana L. and Seaton, Colin C. (2008) Current directions in co-crystal growth. New Journal of Chemistry, 32 (10). pp. 1659-1672. ISSN 1144-0546
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Item Type: | Article |
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Item Status: | Live Archive |
Abstract
In this feature article we will focus on the issues relating to the crystal growth of co-crystals, with a particular emphasis on drug development. The initial focus of this perspective is on the relevant literature examples that may be able to inform our understanding with regards co-crystal crystallisation and the allied supramolecular concepts. The second part of this perspective contains selected examples from our own work, which add to the literature perspective. Topics include; nucleation templates, in situ synchrotron XRD studies, solid-state synthesis through mixing and screening strategies. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.
Keywords: | benzamide, benzoic acid, fumaric acid, ibuprofen, isonicotinamide, nicotinamide, crystal structure, crystallization, hydrogen bond, microscopy, particle size, physical chemistry, priority journal, review, solid state, supramolecular chemistry, synchrotron, synthesis, X ray diffraction |
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Subjects: | B Subjects allied to Medicine > B230 Pharmacy F Physical Sciences > F100 Chemistry |
Divisions: | College of Science > School of Pharmacy |
ID Code: | 8760 |
Deposited On: | 22 Apr 2013 09:38 |
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