The mounting evidence for microdosing

Lappin, Graham (2009) The mounting evidence for microdosing. EBR - European Biopharmaceutical Review (WINTER). pp. 52-54. ISSN 1364-369X

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Drug development pipelines are plagued by increasing costs and decreasing productivity, so techniques that weed out poorly performing compounds early in development are urgently needed. Microdosing studies can potentially provide information about drug behaviour in humans before Phase I, but there have been concerns that such small doses do not reflect a drug's activity at the therapeutic dose. Now there is growing evidence that microdosing studies are useful for many drug types.

Keywords:carbon 14, diphenhydramine, loratadine, drug activity, drug bioavailability, drug cost, drug half life, drug marketing, human, microdosimetry, short survey
Divisions:College of Science > School of Pharmacy
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ID Code:8219
Deposited On:24 Mar 2013 17:23

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