Medical Research Council (2011) WO/2011/018665 Complexing system. .
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Item Type: | Patent |
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Item Status: | Live Archive |
Abstract
The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system.
Additional Information: | The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system. |
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Keywords: | SNAREs proteins, Botulinum neurotoxin |
Subjects: | C Biological Sciences > C710 Applied Molecular Biology, Biophysics and Biochemistry |
Divisions: | College of Science > School of Life Sciences |
Related URLs: | |
ID Code: | 6588 |
Deposited On: | 15 Oct 2012 20:36 |
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