Iemhoff, A., Sherwood, J., McElroy, C. R. and Hunt, A. J. (2018) Towards sustainable kinetic resolution, a combination of bio-catalysis, flow chemistry and bio-based solvents. Green Chemistry, 20 (1). pp. 136-140. ISSN 1463-9262
Full content URL: https://doi.org/10.1039/c7gc03177g
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| Item Type: | Article |
|---|---|
| Item Status: | Live Archive |
Abstract
The esterification of 2-phenylpropionic acid was investigated as a model system for enzyme catalysed (CALB, Novozyme 435) reactions in bio-based solvents. A multi-parameter correlation taking into account solvent parameters was developed to explain experimental observations. A continuous flow process using p-cymene as the solvent was operated over several weeks, thus combining a sustainable solvent and flow chemistry for kinetic resolution.
| Keywords: | biocatalyst, Solvents |
|---|---|
| Subjects: | C Biological Sciences > C720 Biological Chemistry F Physical Sciences > F100 Chemistry |
| Divisions: | College of Science > School of Chemistry |
| Related URLs: | |
| ID Code: | 54756 |
| Deposited On: | 03 Jul 2023 11:16 |
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