Bates, T. E., Loesch, A., Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X
Full content URL: http://www.ingentaconnect.com/content/ap/rc/1996/0...
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| Item Type: | Article |
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| Item Status: | Live Archive |
Abstract
In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed.
| Additional Information: | In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed. |
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| Keywords: | Heart, Skeletal Muscle, Kidney, NOS, eNOS, Nitric Oxide Synthase, Immunocytochemistry, Immumnoelectron microscopy, Electron Microscopy, EM |
| Subjects: | A Medicine and Dentistry > A100 Pre-clinical Medicine B Subjects allied to Medicine > B140 Neuroscience B Subjects allied to Medicine > B200 Pharmacology, Toxicology and Pharmacy A Medicine and Dentistry > A300 Clinical Medicine |
| Divisions: | College of Science > School of Life Sciences |
| ID Code: | 5338 |
| Deposited On: | 18 May 2012 14:45 |
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