Leng, Daniel, Black, Conor M. and Pattison, Graham (2015) One-pot synthesis of difluoromethyl ketones by a difluorination/fragmentation process. Org. Biomol. Chem., 14 . pp. 1531-1535. ISSN 1477-0539
Full content URL: https://doi.org/10.1039/C5OB02468D
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GPDanConor Difluoromethyl ketones OBC Accepted Manuscript.pdf - Whole Document Restricted to Repository staff only 779kB |
| Item Type: | Article |
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| Item Status: | Live Archive |
Abstract
Difluoromethyl ketones are an under-studied class of ketones which have great potential as useful building blocks for materials and drug design. Here we report a simple and convenient synthesis of this class of compounds via a one-pot difluorination/fragmentation of 1-trifluoromethyl-1,3-diketones which should now allow the chemistry of difluoromethyl ketones to be fully developed.
| Keywords: | ketones, fluorination |
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| Subjects: | F Physical Sciences > F100 Chemistry |
| Divisions: | College of Science > School of Chemistry |
| ID Code: | 52246 |
| Deposited On: | 31 Oct 2022 14:19 |
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