Dobson, Luca and Pattison, Graham (2016) Rh-Catalyzed arylation of fluorinated ketones with arylboronic acids. Chemical Communications, 52 (74). pp. 11116-11119. ISSN 1359-7345
Full content URL: https://doi.org/10.1039/C6CC05775F
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GPLuca Arylation fluorinated ketones ChemComm Revised.pdf - Whole Document Restricted to Repository staff only 652kB |
Item Type: | Article |
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Item Status: | Live Archive |
Abstract
The Rh-catalyzed arylation of fluorinated ketones with boronic acids is reported. This efficient process allows access to fluorinated alcohols in high yields under mild conditions. Competition experiments suggest that difluoromethyl ketones are more reactive than trifluoromethyl ketones in this process, despite their decreased electronic activation, an effect we postulate to be steric in origin.
Keywords: | fluorination, boronic acid, rhodium, ketones |
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Subjects: | F Physical Sciences > F100 Chemistry |
Divisions: | College of Science > School of Chemistry |
ID Code: | 52245 |
Deposited On: | 31 Oct 2022 14:24 |
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