Methods for the Synthesis of α,α-Difluoroketones

Pattison, Graham (2018) Methods for the Synthesis of α,α-Difluoroketones. European Journal of Organic Chemistry, 2018 (27-28). pp. 3520-3540. ISSN 1434-193X

Full content URL:

Full text not available from this repository.

Item Type:Article
Item Status:Live Archive


This review describes the key methods for the synthesis of α,α-difluoroketones. These compounds are key synthetic building blocks, as well as being used as enzyme inhibitors. Effective methods for their synthesis include direct fluorination approaches and the use of pre-difluorinated building blocks, including cross-coupling and radical reactions.

Keywords:fluorination, carbonyl derivative, Medicinal chemistry
Subjects:F Physical Sciences > F100 Chemistry
Divisions:College of Science > School of Chemistry
ID Code:52241
Deposited On:31 Oct 2022 14:55

Repository Staff Only: item control page