Intramodal cortical plastic changes after moderate visual impairment in human amblyopia

Mortazavi, Matin, Aigner, Kiera, Antono, Jessica E. , Gambacorta, Christina, Nahum, Mor, Levi, Dennis M. and Foecker, Julia (2022) Intramodal cortical plastic changes after moderate visual impairment in human amblyopia. iScience, 25 (9). ISSN 2589-0042

Full content URL: https://doi.org/10.1016/j.isci.2022.104871

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Intramodal cortical plastic changes after moderate visual impairment in human amblyopia
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Abstract

Early blindness results in alterations in the neural responses to auditory stimuli.
Here we show that even moderately reduced vision in one eye early in life is sufficient
to induce neural plastic changes in voice processing. We asked individuals
with reduced visual acuity in one eye due to amblyopia to attend to vocal cues
during electroencephalogram recording. We found enhanced frontal auditory responses
at 125 ms–225 ms, which were correlated with reduced vision in the
amblyopic eye, but not the fellow eye. Our results indicate intramodal reorganization,
typically observed after congenital profound visual deprivation.

Keywords:neural plasticity, amblyopia, auditory perception
Subjects:C Biological Sciences > C860 Neuropsychology
Divisions:College of Social Science > School of Psychology
ID Code:50478
Deposited On:14 Sep 2022 10:02

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