The Routledge Handbook on Biochemistry of Exercise  book cover
1st Edition

The Routledge Handbook on Biochemistry of Exercise

ISBN 9780367223830
Published December 28, 2020 by Routledge
584 Pages 94 B/W Illustrations

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GBP £190.00

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Book Description

From its early beginnings in the 1960s, the academic field of biochemistry of exercise has expanded beyond examining and describing metabolic responses to exercise and adaptations to training to include a wide understanding of molecular biology, cell signalling, interorgan communication, stem cell physiology, and a host of other cellular and biochemical mechanisms regulating acute responses and chronic adaptations related to exercise performance, human health/disease, nutrition, and cellular functioning.

The Routledge Handbook on Biochemistry of Exercise is the first book to pull together the full depth and breadth of this subject and to update a rapidly expanding field of study with current issues and controversies and a look forward to future research directions. Bringing together many experts and leading scientists, the book emphasizes the current understanding of the underlying metabolic, cellular, genetic, and cell signalling mechanisms associated with physical activity, exercise, training, and athletic performance as they relate to, interact with, and regulate cellular and muscular adaptations and consequent effects on human health/disease, nutrition and weight control, and human performance.

With more emphasis than ever on the need to be physically active and the role that being active plays in our overall health from a whole-body level down to the cell, this book makes an important contribution for scholars, medical practitioners, nutritionists, and coaches/trainers working in research and with a wide range of clients. This text is important reading for all students, scholars, and others with an interest in health, nutrition, and exercise/training in general.

Table of Contents

Section 1 - Regulation of metabolism and responses to acute exercise


Rebecca EK MacPherson

1. Whole Body Regulation of Energy Expenditure, Exercise Fuel Selection, and Dietary Recommendations

Peter WR Lemon

2. Energy Provision, Fuel Use and Regulation of Skeletal Muscle Metabolism During the Exercise Intensity/Duration Continuum

Lawrence L Spriet

3. Adipose Tissue (adipokinome), Skeletal Muscle (myokinome) and Liver (hepatokinome) as Endocrine Regulators during Exercise

Logan K. Townsend, Greg L. McKie, Hesham Shamshoum, and David C. Wright

4. Regulation of Skeletal Muscle Reactive Oxygen Species During Exercise

Catherine A. Bellissimo and Christopher G.R. Perry

5. Biochemical contributors to exercise fatigue

Arthur J Cheng, Maja Schlittler, and Håkan Westerblad

6. Mechanotransduction Mechanisms of Hypertrophy and Performance with Resistance Exercise

Andrew C. Fry, Justin X. Nicoll, and Luke A. Olsen

7. Responses to muscular exercise, Heat Shock Proteins as regulators of inflammation and mitochondrial quality control

Alex T. Von Schulze and Paige C. Geiger

8. Signaling pathways in regulation of cellular responses to exercise

Anders Gudiksen, Stine Ringholm and Henriette Pilegaard

Section II: Exercise Biochemistry, Chronic Training, and Athletic Performance


Paul J LeBlanc

9. Exercise-Induced Mitochondrial Biogenesis: Molecular Regulation, Impact of Training, and Influence on Exercise Performance

Hashim Islam, Jacob T. Bonafiglia, Cesare Granata, and Brendon J. Gurd

10: Resistance Exercise Training and the Regulation of Muscle Protein Synthesis

Nathan Hodson, Daniel R. Moore, and Chris McGlory

11: Cellular Adaptations to High-Intensity and Sprint Interval Training

Martin J. MacInnis and Lauren E. Skelly

12: Regulation of Muscle Satellite Cell Activation and Cycles Consequent to Various Forms of Training

Sophie Joanisse and Gianni Parise

13: Biochemical and Metabolic Limitations to Athletic Performance

Brendan M. Gabriel

14: Genetic Limitations to Athletic Performance

Colin N Moran and Guan Wang

15: The Role of Epigenetics in Skeletal Muscle Adaptations to Exercise and Exercise Training

Sean L. McGee

16: Statistical Considerations and Biological Mechanisms Underlying Individual Differences in Adaptations to Exercise Training

Jacob T. Bonafiglia, Hashim Islam, Nir Eynon, and Brendon J. Gurd

17: Effects of Hypoxia/Blood Flow Restriction on Cellular Adaptations to Training

Scott J. Dankel and Jeremy P. Loenneke


Section III: Exercise Biochemistry/Nutrition Nexus in Sport and Physical Activity


Andrea R Josse

18: Exercise and Dietary Influences on the Regulation of Energy Balance and Implications for Body Weight Control

Andrea M. Brennan and Robert Ross

19: Dietary Manipulation for Optimizing Endurance Training Adaptations and Performance: Carbohydrate vs. Fat

Jamie Whitfield and Louise M. Burke

20: Dietary Influence on Muscle Protein Synthesis and Hypertrophy

James McKendry and Stuart M. Phillips

21: Micronutrients and Nutraceuticals: Effects on Exercise Performance

Stella L. Volpe and Quentin Nichols

22: Biochemistry of Buffering Capacity and Ingestion of Buffers in Exercise and Athletic Performance

Bryan Saunders, Guilherme G. Artioli, Eimear Dolan, Rebecca L. Jones, Joseph Matthews, and Craig Sale

23: Creatine augmentation for muscle and bone responses to exercise

Philip D. Chilibeck

24: Biochemistry of Caffeine's Influence on Exercise Performance

Jane Shearer, Robyn F. Madden , and Jill A. Parnell

25: Nutrigenomics for Sport and Exercise Performance

Nanci S. Guest, Marc Sicova , and Ahmed El-Sohemy

Section IV: Exercise Biochemistry Relative to Health Through the Lifespan


Peter M Tiidus

26: Mitochondrial Dysfunction in Chronic Disease

Christopher Newell, Heather Leduc-Pessah, Aneal Khan and Jane Shearer

27: Exercise training, mitochondrial adaptations and aging

Nashwa Cheema, Matthew Triolo and David.A. Hood,

28: Biochemistry of Exercise Effects in Type II Diabetes

Barry Braun, Karyn L. Hamilton, Dan S. Lark and Alissa Newman

29: Biochemistry of Exercise Training and Mitigation of Cardiovascular Disease

Barry A. Franklin and John C. Quindry

30: Biochemistry of Exercise Training and Type 1 Diabetes

Sam N. Scott, Matt Cocks, Anton J. M. Wagenmakers, Sam O. Shepherd and Michael C. Riddell

31: Biochemistry of Exercise Training: Mitigation of Cancers

Brittany R. Counts, Jessica L. Halle and James A. Carson

32: Biochemistry of Exercise Training; Effects on Bone

Panagiota Klentrou and Rozalia Kouvelioti

33: Metabolic Effects of Exercise on Childhood Obesity

Kristi B. Adamo, Taniya S. Nagpal and Danilo F. DaSilva

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