Pigs as a potential source of emerging livestock-associated Staphylococcus aureus in Africa: a systematic review

Samutela, Mulemba Tillika, Kwenda, Geoffrey, Simulundu, Edgar , Nkhoma, Panji, Higashi, Hideaki, Frey, Andrew, Bates, Matthew and Hang'ombe, Bernard M. (2021) Pigs as a potential source of emerging livestock-associated Staphylococcus aureus in Africa: a systematic review. International Journal of Infectious Diseases, 109 . pp. 38-49. ISSN 1201-9712

Full content URL: https://doi.org/10.1016/j.ijid.2021.06.023

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Pigs as a potential source of emerging livestock-associated Staphylococcus aureus in Africa: a systematic review
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Abstract

Objective: To assess the emergence of livestock-associated Staphylococcus aureus including methicillin-resistant S. aureus (MRSA) in the pig and pork production systems in Africa for the past two decades.

Methods: PubMed and African Journals OnLine were searched for relevant primary studies from 2000 to 2019 using standardized key words. In total, 19 eligible articles were included in this review.

Results: The prevalence of S. aureus including MRSA ranged from 0% to 55% among live pigs and raw pork, and from 9.4% to 30.8% among pig farm and abattoir workers. Risk factors associated with S. aureus carriage among workers were: male gender, working in an abattoir, and medical-related occupation of a household member. S. aureus and MRSA from pigs and pork production systems in Africa are potentially pathogenic with diverse spa types and clonal complexes, with genes encoding antimicrobial resistance, heavy metal resistance, and virulence factors including secreted and enterotoxins, proteases and immune evasion cluster. The typical livestock-associated S. aureus CC398 and mecC genes were reported in two studies.

Conclusion: Pigs are a potential source of the emerging livestock-associated S. aureus in Africa. Continued monitoring using a 'One Health' approach is recommended for effective infection prevention and control of these infections in Africa.

Keywords:Africa; Antimicrobial resistance; Livestock-associated-MRSA; Pigs; Staphylococcus aureus; Systematic review
Subjects:C Biological Sciences > C522 Veterinary Microbiology
C Biological Sciences > C520 Medical and Veterinary Microbiology
C Biological Sciences > C521 Medical Microbiology
Divisions:College of Science > School of Life Sciences
ID Code:48674
Deposited On:24 Mar 2022 13:43

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