Platelet mimicry: The emperor's new clothes?

Moghimi, Seyed Moein, Hunter, Alan Christy and Peer, Dan (2016) Platelet mimicry: The emperor's new clothes? Nanomedicine: Nanotechnology, Biology and Medicine, 12 (1). pp. 245-248. ISSN 1549-9634

Full content URL: https://doi.org/10.1016/j.nano.2015.09.005

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Item Type:Article
Item Status:Live Archive

Abstract

Here we critically examine whether coating of nanoparticles with platelet membranes can truly disguise them against recognition by elements of the innate immune system. We further assess whether the “cloaking technology” can sufficiently equip nanoparticles with platelet-mimicking functionalities to include in vivo targeting of damaged blood vessels and binding to platelet-adhering opportunistic pathogens. We present views for improved, and pharmaceutically viable nanoparticle design strategies.

Divisions:College of Science > School of Pharmacy
ID Code:45544
Deposited On:29 Jun 2021 15:50

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