Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa

Mogeni, Polycarp, Vandormael, Alain, Cuadros, Diego , Appleton, Christopher and Tanser, Frank (2020) Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa. eLife, 9 . ISSN 2050-084X

Full content URL: https://doi.org/10.7554/eLife.54012

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Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa
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Abstract

Previously, we demonstrated that coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1976 primary school children (Tanser, 2018). Here, we report on the prospective follow up of infected members of this nested cohort (N = 333) for two successive rounds following treatment. Using a negative binomial regression fitted to egg count data, we found that every percentage point increase in piped water coverage was associated with 4.4% decline in intensity of re-infection (incidence rate ratio = 0.96, 95% CI: 0.93–0.98, p=0.004) among the treated children. We therefore provide further compelling evidence in support of the scaleup of piped water as an effective control strategy against Schistosoma haematobium transmission.

Keywords:Epidemiology and Global Health, Microbiology, Infectious Diseases, piped water coverage, S. haematobium, re-infection, primary school children, South Africa
Subjects:B Subjects allied to Medicine > B990 Subjects Allied to Medicine not elsewhere classified
Divisions:College of Social Science
ID Code:41625
Deposited On:23 Jul 2020 12:17

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