Directed and Modular Protein Immobilization on Gold and Silver Nanoparticles

Saccardo, Angela, Ma, Wenwei, Soloviev, Mikhail and Ferrari, Enrico (2020) Directed and Modular Protein Immobilization on Gold and Silver Nanoparticles. In: Nanoparticles in Biology and Medicine. Springer, pp. 227-234. ISBN 978-1-0716-0319-2

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Conjugation of proteins to gold nanoparticles (AuNP), silver nanoparticles (AgNP), or other metal nanoparticles (NPs) can often be achieved using passive adsorption. Although such an approach is simple and effective, there is usually no control over the orientation of the protein and denaturation due to close contact with the metal surface. The method described here makes use of adapter proteins which have the ability to adsorb to the NP surface in an oriented and stable way and at the same time enable straightforward attachment to other proteins of interest.

Subjects:B Subjects allied to Medicine > B990 Subjects Allied to Medicine not elsewhere classified
Divisions:College of Science > School of Life Sciences
ID Code:40206
Deposited On:15 Apr 2020 13:19

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