Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree

Iyavoo, Sasitaran, Alghafri, Rashed, Almheiri, Reem and Haizel, Thomas (2019) Evaluation of 13 rapidly mutating Y-STRs on a Dravidian pedigree. Forensic Science International: Genetics Supplement Series, 7 (1). pp. 216-217. ISSN 1875-1768

Full content URL: https://doi.org/10.1016/j.fsigss.2019.09.083

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Item Type:Article
Item Status:Live Archive


The effectiveness of a rapidly mutating Y-STRs multiplex assay (RM Y-STRs) containing 13 RM Y-STR markers was compared with the AmpFℓSTR™ Yfiler™ PCR Amplification Kit (Yfiler) with conventional Y-STR markers for their efficiency in differentiating males within the same paternal lineage. Samples from 4 generations comprising 16 Dravidian males (15 father-son pairs) were analysed with both assays. Mutations were observed in 3 father-son pairs in the RM Y-STRs profiles while only 2 mutations were observed in the Y-filer profiles. Even though not many mutations were observed as anticipated, this study still emphasised the importance of RM Y-STRs when differentiation between males within the same paternal lineage is required and also indicated the need for mutation rates for different populations.

Keywords:Rapidly mutating Y-STRs, Multiplex assay, Mutation, Dravidian pedigree
Subjects:F Physical Sciences > F410 Forensic Science
Divisions:College of Science > School of Chemistry
ID Code:39385
Deposited On:08 Jan 2020 08:59

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