Riess, Nicholas, Milward, Kelly, Lee, Tracy , Adams, Matthew, Askham, Jon M and Morrison, Ewan E (2005) Trapping of normal EB1 ligands in aggresomes formed by an EB1 deletion mutant. BMC Cell Biology, 6 (1). p. 17. ISSN 1471-2121
Full content URL: http://doi.org/10.1186/1471-2121-6-17
| Documents |
| ||||
|
PDF
10.1186%2F1471-2121-6-17.pdf - Whole Document Available under License Creative Commons Attribution 4.0 International. 9MB |
| Item Type: | Article |
|---|---|
| Item Status: | Live Archive |
Abstract
EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and the p150glued subunit of dynactin. We previously reported that an EB1 deletion mutant that retains both of these interactions but does not directly associate with microtubules (EB1-ΔN2-GFP) spontaneously formed perinuclear aggregates when expressed in COS-7 cells.
| Keywords: | Aggresomes, EB1, Microtubules |
|---|---|
| Subjects: | C Biological Sciences > C130 Cell Biology |
| Divisions: | College of Science > School of Chemistry |
| ID Code: | 31319 |
| Deposited On: | 23 Jul 2018 14:32 |
Repository Staff Only: item control page