Production of glucosamine from chitin by co-solvent promoted hydrolysis and deacetylation

Zhang, Jiaguang and Yan, Ning (2017) Production of glucosamine from chitin by co-solvent promoted hydrolysis and deacetylation. ChemCatChem, 9 (14). pp. 2790-2796. ISSN 1867-3880

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Production of renewable chemicals with established market and high value is highly desirable in biomass utilization. Herein, glucosamine, an amino sugar with various applications, was generated in a single step by the acid-catalyzed transformation of chitin. Aprotic polar solvents were mixed with water to promote the hydrolysis as well as the deacetylation reactions, significantly enhancing product yield and/or reducing the concentration and amount of acid catalyst required. By employing the optimized co-solvent system, glucosamine was achieved with 80 % yield at 175 °C in 1 h from ball-milled chitin, in sharp contrast with the pure water system with the same acid concentration in which less than 1 % glucosamine was obtained. Correlations between the promotional effect and various solvent property parameters were discussed and proposed, providing guidance on the choice of solvent for further optimization of the co-solvent system for similar applications.

Keywords:acid-catalyzed, chitin, co-solvent, glucosamine, hydrolysis
Subjects:F Physical Sciences > F100 Chemistry
Divisions:College of Science > School of Chemistry
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ID Code:30560
Deposited On:06 Mar 2018 09:42

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