Trends in Childhood Tuberculosis in Zambia: A Situation Analysis

Kapata, Nathan, Chanda-Kapata, Pascalina, O'Grady, Justin , Bates, Matthew, Mwaba, Peter, Janssen, Saskia, Marais, Ben, Cobelens, Frank, Grobusch, Martin and Zumla, Alimuddin (2012) Trends in Childhood Tuberculosis in Zambia: A Situation Analysis. JOURNAL OF TROPICAL PEDIATRICS, 59 (2). pp. 134-139. ISSN 0142-6338

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Objectives: To ascertain childhood tuberculosis (TB) trends, human immunodeficiency virus (HIV) co-infection rates and multi-drug resistant TB (MDR-TB) prevalence rates in Zambia. Methods: A retrospective review of Zambian annual TB notification data and National TB Programme reports for a 7 year period (2004-2011). TB trends were stratified by age and HIV status. Results: The total number of children notified during this period with all forms of TB was 40 976. A total of 2670 of 40 976 (6%) were smear-positive cases. Notification rates of all forms of childhood TB show a decline in trends from 135 per 100 000 population in 2004, to 69 per 100 000 population in 2011. Conclusions: Childhood TB is an important but neglected problem in Zambia highlighted by the fact that no data exists on HIV co-infection and MDR-TB. Strengthening of the National TB Programme and diagnostics services/algorithms are required to accurately define the TB burden, HIV co-infection and MDR-TB rates in children in Zambia.

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Keywords:T, HIV, childhood, Zambia, epidemiology}
Subjects:A Medicine and Dentistry > A300 Clinical Medicine
Divisions:College of Science > School of Life Sciences
ID Code:28389
Deposited On:30 Jul 2018 08:41

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