Elhissi, A.M.A.a, Ahmed, W.b, McCarthy, D.c and Taylor, K.M.G.a c (2012) A Study of Size, Microscopic Morphology, and Dispersion Mechanism of Structures Generated on Hydration of Proliposomes. Journal of Dispersion Science and Technology, 33 (8). pp. 1121-1126. ISSN 01932691
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| Item Type: | Article |
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| Item Status: | Live Archive |
Abstract
Proliposomes were made by coating lactose monohydrate (LMH), sucrose or sorbitol particles with phosphatidylcholine. Proliposomes hydrated under static (i.e., no shaking) conditions instantly generated liposomes which deaggregated immediately using sorbitol carrier and over a period of 5 minutes using LMH or sucrose particles. Manual dispersion of sucrose-based or sorbitol-based proliposomes generated spherical vesicles, while vesicles generated from LMH-based proliposomes were rich in elongated wormlike structures. The effect of formulation on liposome size was minimal. Overall, carrier type and hydration procedure of proliposomes had a marked effect on liposome morphology while formulation had minimal effect on liposome size. © 2012 Copyright Taylor and Francis Group, LLC.
| Additional Information: | cited By 7 The final published version of this article can be accessed online at https://www.tandfonline.com/doi/abs/10.1080/01932691.2011.599233 |
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| Keywords: | Dispersion mechanisms, Microscopic morphology, Minimal effects, Phosphatidylcholine, proliposome, Proliposomes, Wormlike structures, Alcohols, Dispersion (waves), Dispersions, Liposomes, Morphology, Sugar (sucrose), Sugars, Hydration |
| Subjects: | F Physical Sciences > F200 Materials Science J Technologies > J510 Materials Technology |
| Divisions: | College of Science > School of Mathematics and Physics |
| ID Code: | 27164 |
| Deposited On: | 01 Aug 2018 08:42 |
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