Diagnostic target

University of Lincoln (2016) Diagnostic target. .

WO2016193714-PAMPH-888.pdf - Whole Document

Item Type:Patent
Item Status:Live Archive


A method for the diagnosis of Type 1 diabetes, or a predisposition towards Type 1 diabetes, or to monitor the efficacy of a therapy to prevent or treat Type 1 diabetes, said method comprising contacting a sample from a subject with a reagent selected from Tetraspanin-7 or a fragment, or a modified form thereof, and detecting an interaction indicative of the presence of an autoimmune response to Tetraspanin-7. Tetraspanin-7 is now understood to be the protein recognised by Glima 38 specific antibodies. dReagents and kits for use in the method and therapies associated with these form further aspects of the invention.

Keywords:type 1 diabetes, autoantibody, autoimmune disease, Diagnostics
Subjects:C Biological Sciences > C550 Immunology
A Medicine and Dentistry > A300 Clinical Medicine
Divisions:College of Science > School of Life Sciences
ID Code:25358
Deposited On:28 Dec 2016 20:22

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