Positron emission tomography and histopathology in Creutzfeldt-Jakob disease

Goldman, S., Liard, A., Flament-Durand, J. , Luxen, A., Bidaut, L. M., Stanus, E., Hildebrand, J. and Przedborski, S. (1993) Positron emission tomography and histopathology in Creutzfeldt-Jakob disease. Neurology, 43 (9). pp. 1828-1830. ISSN 0028-3878

Full text not available from this repository.

Item Type:Article
Item Status:Live Archive


We studied a 62-year-old man with Creutzfeldt-Jakob disease (CJD), using positron emission tomography (PET) and (18F)-2-fluoro-2-deoxy-D-glucose (FDG). Glucose metabolism was heterogeneously decreased throughout the brain. At autopsy, regional distributions of spongiosis, astrogliosis, and neuronal loss correlated with premortem regional metabolic deficits. These results suggest that PET with FDG may provide metabolic regional markers for CJD neuropathology.

Keywords:adult, article, autopsy, brain metabolism, case report, creutzfeldt jakob disease, glucose metabolism, histopathology, human, male, neuropathology, positron emission tomography, priority journal, Brain, Creutzfeldt-Jakob Syndrome, Glucose, Middle Age, Support, Non-U.S. Gov't, Tomography, Emission-Computed
Subjects:F Physical Sciences > F350 Medical Physics
Divisions:College of Science > School of Computer Science
Related URLs:
ID Code:24179
Deposited On:25 Oct 2016 17:25

Repository Staff Only: item control page