Abstract

Tortuosity is believed to be an early indicator of
the changes in the retinal vasculature during the progression of
diabetes. Different methods have been proposed in literature
but their application in progressed patients (from diabetes to DR) has been inadequate. In this study we measured and calculated different metrics of tortuosity using twenty fives diabetic patients in two time intervals; 3-4 years before DR and the first year of diabetic retinopathy. The standard deviation of the tortuosity measurements differed significantly showing an increase in the variability of tortuosity in the vasculature in the
first year of DR by 19.6%