A microparticle assembly

National University of Singapore (2013) A microparticle assembly. WO2013176625 A1.

Full content URL: https://www.google.com/patents/WO2013176625A1

Patent WO2013176625A1 - A microparticle assembly - Google Patents.pdf
Patent WO2013176625A1 - A microparticle assembly - Google Patents.pdf - Whole Document

Item Type:Patent
Item Status:Live Archive


A microarray, comprising a plurality of bead constructs disposed thereon, wherein the bead constructs comprise: (a) a bead; (b) a fluorophore molecule, wherein the fluorophore molecule comprises at least two subunits connected to each other by at least one internal linker that provides conformational freedom to the at least two subunits, and wherein the optical signal emitted by the flurophore changes when reducing the conformational freedom of the at least two subunits to each other; (c) a first linker molecule connected to the bead and to one of the subunits of the flurophore molecule; (d) a second linker molecule connected to another subunit of the fluorophore molecule; and (e) a ligand molecule connected to the second linker.

Additional Information:Also published as EP2839284A1.
Keywords:Bead microarray, Smart optical linkers, Fluorescent sensing, Detection of binding events
Subjects:F Physical Sciences > F200 Materials Science
F Physical Sciences > F170 Physical Chemistry
F Physical Sciences > F160 Organic Chemistry
Divisions:College of Science > School of Chemistry
ID Code:17182
Deposited On:23 Apr 2015 14:07

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