Singh, Ishwar, Vyle, Joseph S. and Heaney, Frances (2009) Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation. Chemical Communications, 45 (22). pp. 3276-3278. ISSN 1359-7345
Full content URL: http://dx.doi.org/10.1039/b904185k
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| Item Type: | Article |
|---|---|
| Item Status: | Live Archive |
Abstract
Solid-phase oligonucleotide conjugation by nitrile oxide-alkyne click cycloaddition chemistry has been successfully demonstrated; the reaction, compatible with all nucleobases, requires no metal catalyst and proceeds under physiological conditions.
| Additional Information: | First published online 22 Apr 2009 |
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| Keywords: | Oligonucleotides |
| Subjects: | B Subjects allied to Medicine > B200 Pharmacology, Toxicology and Pharmacy |
| Divisions: | College of Science > School of Pharmacy |
| ID Code: | 11301 |
| Deposited On: | 24 Jul 2013 13:06 |
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