Singh, Ishwar and Heaney, Frances (2011) Solid phase strain promoted "click'' modification of DNA via [3+2]-nitrile oxide-cyclooctyne cycloadditions. Chemical Communications, 47 (9). pp. 2706-2708. ISSN 1359-7345
Full content URL: http://dx.doi.org/10.1039/c0cc03985c
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| Item Type: | Article |
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| Item Status: | Live Archive |
Abstract
Rapid, catalyst free, solid phase modification of DNA by strain promoted cyclooctyne-nitrile oxide click chemistry is reported; the reaction is characterised by mild conditions, occurring in an aqueous environment under atmospheric conditions at room temperature and is complete in 10 minutes.
| Additional Information: | First published online 21 Dec 2010 |
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| Keywords: | DNA |
| Subjects: | B Subjects allied to Medicine > B200 Pharmacology, Toxicology and Pharmacy |
| Divisions: | College of Science > School of Pharmacy |
| ID Code: | 11295 |
| Deposited On: | 24 Jul 2013 11:46 |
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