The antibacterial potency of the medicinal maggot, Lucilia sericata (Meigen): variation in laboratory evaluation

Barnes, Kirsty M., Dixon, Ron A. and Gennard, Dorothy E. (2010) The antibacterial potency of the medicinal maggot, Lucilia sericata (Meigen): variation in laboratory evaluation. Journal of Microbiological Methods, 82 (3). pp. 234-237. ISSN 0167-7012

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Research to quantify the potency of larval excretion/secretion from Lucilia sericata using liquid culture assays has produced contradictory results. In this study, viable counting was used to investigate the effectiveness of excretion/secretion against three marker bacterial species (Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli) and the effects of varying growing conditions in assays. Results demonstrate that factors such as number of larvae, species of bacteria and addition of nutrient influence its antibacterial potency. Therefore a standardised method should be employed for liquid culture assays when investigating the antibacterial activity of larval excretion/secretion from L. sericata. © 2010 Elsevier B.V.

Keywords:antibacterial activity, article, bacterial growth, controlled study, Escherichia coli, genetic variability, growth inhibition, liquid culture, lucilia sericata, maggot, nonhuman, priority journal, Pseudomonas aeruginosa, Staphylococcus aureus, Animals, Anti-Bacterial Agents, Bacteria, Diptera, Laboratory Techniques and Procedures, Larva, Research Design, Bacteria (microorganisms), Hexapoda, Staphylococcus aureus
Subjects:B Subjects allied to Medicine > B290 Pharmacology, Toxicology and Pharmacy not elsewhere classified
Divisions:College of Science > School of Life Sciences
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ID Code:10104
Deposited On:19 Dec 2013 10:32

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