Items where Subject is "F Physical Sciences > F165 Biomolecular Chemistry"

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Number of items at this level: 25.


Aubin-Tam, Marie-Eve and Appleyard, David C. and Ferrari, Enrico and Garbin, Valeria and Fadiran, Oluwatimilehin O. and Kunkel, Jacquelyn and Lang, Matthew J. (2011) Adhesion through single peptide aptamers. The Journal of Physical Chemistry A, 115 (16). pp. 3657-3664. ISSN 1089-5639


Ch'ng, J.-H. and Kotturi, S. R. and Chong, A. G.-L. and Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

Ch'ng, Jun-Hong and Mok, Sachel and Bozdech, Zbynek and Lear, Martin James and Boudhar, Aicha and Russell, Bruce and Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322


Ghosh, Shibaji K. and Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039


Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.

Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain.

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Lear, Martin and Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.

Lear, Martin J. and Simon, Oliver and Foley, Timothy L. and Burkart, Michael D. and Baiga, Thomas J. and Noel, Joseph P. and DiPasquale, Antonio G. and Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Loh, Cheryl C. Y. and Suwanarusk, Rossarin and Lee, Yan Quan and Chan, Kitti W. K. and Choy, Kit-Ying and Rénia, Laurent and Russell, Bruce and Lear, Martin J. and Nosten, François H. and Tan, Kevin S. W. and Chow, Larry M. C. and Snounou, Georges (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE, 9 (10). e110800. ISSN 1932-6203


Ngai, Mun H. and Yang, Peng-Yu and Liu, Kai and Shen, Yuan and Wenk, Markus R. and Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345


Pasari, Sandip and Ismail, Shareef M. and Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039


Roccatano, Danilo (2015) Structure, dynamics, and function of the monooxygenase P450 BM-3: insights from computer simulations studies. Journal of Physics: Condensed matter : an Institute of Physics journal, 27 (27). p. 273102. ISSN 0953-8984

Rodríguez, Abimael D. and Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863


Simon, Oliver and Reux, Bastien and La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Song, Hong Y. and Ngai, Mun H. and Song, Zhen Y. and MacAry, Paul A. and Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520


Tan, Kevin and Lear, Martin (2010) Scientists tag malaria superbugs. Singapore Press Holdings.

Tejasvi, Amrita and Lear, Martin and Tan, Kevin (2012) Enhancing malaria research. Project Report. CyberMedia.


Yamada, Kei and Lear, Martin J. and Yamaguchi, Takaya and Yamashita, Shuji and Gridnev, Ilya D. and Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic total synthesis of cyanosporaside aglycons from a single enediyne precursor through site-selective p-benzyne hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

Yang, Peng-Yu and Liu, Kai and Ngai, Mun Hong and Lear, Martin J. and Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Yang, Peng-Yu and Liu, Kai and Zhang, Chongjing and Chen, Grace Y. J. and Shen, Yuan and Ngai, Mun Hong and Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

Yang, Peng-Yu and Wang, Min and Liu, Kai and Ngai, Mun Hong and Sheriff, Omar and Lear, Martin J. and Sze, Siu Kwan and He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

This list was generated on Sat Nov 28 08:34:55 2015 GMT.