Items where Subject is "F Physical Sciences > F163 Bio-organic Chemistry"

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Number of items at this level: 24.

C

Ch'ng, J.-H. and Kotturi, S. R. and Chong, A. G.-L. and Lear, Martin J. and Tan, K. S.-W. (2010) A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death and Disease, 1 (2). e26. ISSN 2041-4889

Ch'ng, Jun-Hong and Mok, Sachel and Bozdech, Zbynek and Lear, Martin James and Boudhar, Aicha and Russell, Bruce and Nosten, Francois and Tan, Kevin Shyong-Wei (2013) A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Scientific Reports, 3 (1734). ISSN 2045-2322

F

Freeman, Colin and Cheallaigh, Aisling Ni and Singh, Ishwar and Heaney, Frances (2015) Isoxazole linked oligonucleotide conjugates by on resin and previously clicked nitrile oxide alkyne cycloadditions. Collection of Czechoslovak Chemical Communications, 12 . p. 333. ISSN 0010-0765

G

Ghosh, Shibaji K. and Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

H

Henry, Sarah L. and Withers, Jamie M. and Singh, Ishwar and Cooper, Jonathan M. and Clark, Alasdair W. and Burley, Glenn A. and Cogdell, Richard J. (2015) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic & Biomolecular Chemistry, 14 (4). pp. 1359-1362. ISSN 1477-0520

K

Kyne, S. H. and Miles, J. A. L. and Percy, J. M. and Singh, K. (2012) Executing and rationalizing the synthesis of a difluorinated analogue of a ring-expanded calystegine B2. Journal of Organic Chemistry, 77 (2). pp. 991-998. ISSN 0022-3263

L

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.

Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain.

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Lear, Martin and Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.

Lear, Martin J. and Simon, Oliver and Foley, Timothy L. and Burkart, Michael D. and Baiga, Thomas J. and Noel, Joseph P. and DiPasquale, Antonio G. and Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

N

Ngai, Mun H. and Yang, Peng-Yu and Liu, Kai and Shen, Yuan and Wenk, Markus R. and Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

P

Parmar, Anish and Iyer, Abhishek and Vincent, Charlotte and Van Lysebetten, Dorien and Prior, Stephen H. and Madder, Annemieke and Taylor, Edward J. and Singh, Ishwar (2016) Efficient total syntheses and biological activities of two teixobactin analogues. Chemical Communications, 52 (36). pp. 6060-6063. ISSN 1359-7345

Pasari, Sandip and Ismail, Shareef M. and Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

R

Rodríguez, Abimael D. and Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

Roe, S. and Gunaratnam, M. and Spiteri, C. and Sharma, Pallavi and Alharthy, R. D. and Neidle, S. and Moses, J. E. (2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Organic and Biomolecular Chemistry, 13 . pp. 8500-8504. ISSN 1477-0520

S

Simon, Oliver and Reux, Bastien and La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Singh, Ishwar and Heaney, Frances and Batchelor, Caroline and Vyle, Joseph S. (2015) Metal free click chemistry on nucleosides and oligonucleotides. Collection of Czechoslovak Chemical Communications, 10 . p. 451. ISSN 0010-0765

Song, Hong Y. and Ngai, Mun H. and Song, Zhen Y. and MacAry, Paul A. and Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520

Y

Yamada, Kei and Lear, Martin J. and Yamaguchi, Takaya and Yamashita, Shuji and Gridnev, Ilya D. and Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic total synthesis of cyanosporaside aglycons from a single enediyne precursor through site-selective p-benzyne hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

Yang, Peng-Yu and Liu, Kai and Ngai, Mun Hong and Lear, Martin J. and Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Yang, Peng-Yu and Wang, Min and Liu, Kai and Ngai, Mun Hong and Sheriff, Omar and Lear, Martin J. and Sze, Siu Kwan and He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

This list was generated on Thu Aug 17 14:34:37 2017 BST.