Items where Subject is "F Physical Sciences > F160 Organic Chemistry"

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Article

Ali, Asif and Wenk, Markus R. and Lear, Martin J. (2009) Total synthesis of a fully lipidated form of phosphatidyl-myo-inositol dimannoside (PIM-2) of Mycobacterium tuberculosis. Tetrahedron Letters, 50 (40). pp. 5664-5666. ISSN 0040-4039

Chavan, Subhash P and Praveen, Cherukupally and Sharma, Pallavi and Kalkote, U. R. (2005) An efficient stereoselective synthesis of (2S,4S,5R)-(-)- and (2R,4R,5S)-(+)-bulgecinine. Tetrahedron Letters, 46 (3). pp. 439-441. ISSN 0040-4039

Chavan, Subhash P. and Sharma, Pallavi and Ramakrishna, G. and Thakkar, Mahesh (2003) Iodine as an efficient catalyst in ionic Diels–Alder reactions of α,β-unsaturated acetals. Tetrahedron Letters, 44 (14). pp. 3001-3003. ISSN 0040-4039

Chavan, Subhash P. and Sharma, Pallavi and Sivappa, R. and Kalkote, Uttam R. (2006) A ring closing metathesis approach to the indole alkaloid mitralactonine. Tetrahedron Letters, 47 (52). pp. 9301-9303. ISSN 0040-4039

Chavan, Subhash P. and Sharma, Pallavi and Sivappa, Rasapalli and Bhadbhade, Mohan B. and Gonnade, Rajesh G. and Kalkote, Uttam R. (2003) Enantioselective synthesis of L-CCG-I. Journal of the American Chemical Society, 68 (17). pp. 6871-6819. ISSN 0002-7863

Chavan, Subhash P. and Sharma, Pallavi and Sivappa, Rasapalli and Kalkote, Uttam R. (2007) A practical and facile approach towards indole alkaloids: (-)-mitralactonine. Synlett, 2007 (01). pp. 79-82. ISSN 0936-5214

Cousins, Alex R. O. and Ritson, Dougal and Sharma, Pallavi and Stevens, Malcolm F. G. and Moses, John E. and Searle, Mark S. (2014) Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences. Chemical Communications, 50 . pp. 15202-15205. ISSN 1359-7345

Das, Parthasarathi and Mita, Takashi and Lear, Martin and Hirama, Masahiro (2002) Synthesis of 13C-labelled, bicyclic mimetics of natural enediynes. Chemical Communications (22). pp. 2624-2625. ISSN 1359-7345

Eey, Stanley T.-C. and Lear, Martin J. (2014) Total synthesis of (−)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods. Chemistry - A European Journal, 20 (36). pp. 11556-11573. ISSN 0947-6539

Eey, Stanley T.-C. and Lear, Martin J. (2010) A bismuth(III)-catalyzed Friedel−Crafts cyclization and stereocontrolled organocatalytic approach to (−)-platensimycin. Organic Letters, 12 (23). pp. 5510-5513. ISSN 1523-7060

Fallows, Andrew J. and Singh, Ishwar and Dondi, Ruggero and Cullis, Paul M. and Burley, Glenn A. (2014) Highly efficient synthesis of DNA-binding polyamides using a convergent fragment-based approach. Organic Letters, 16 (17). pp. 4654-4657. ISSN 1523-7060

Ghosh, Shibaji K. and Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

Ghosh, Shibaji K. and Somanadhan, Brinda and Tan, Kevin S.-W. and Butler, Mark S. and Lear, Martin J. (2012) Absolute configuration and total synthesis of a novel antimalarial lipopeptide by the de novo preparation of chiral nonproteinogenic amino acids. Organic Letters, 14 (6). pp. 1560-1563. ISSN 1523-7060

Hirama, Masahiro and Akiyama, Kimio and Das, Parthasarathi and Mita, Takashi and Lear, Martin J. and Iida, Kyo-ichiro and Sato, Itaru and Yoshimura, Fumihiko and Usuki, Toyonobu and Tero-Kubota, Shozo (2006) Direct observation of ESR spectra of bicyclic nine-membered enediynes at ambient temperature. Heterocycles, 69 (1). pp. 83-89. ISSN 0385-5414

Kobayashi, Shoji and Ashizawa, Shukuko and Takahashi, Yusuke and Sugiura, Yukio and Nagaoka, Makoto and Lear, Martin J. and Hirama, Masahiro (2001) The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage. Journal of the American Chemical Society, 123 (45). pp. 11294-11295. ISSN 0002-7863

Kobayashi, Shoji and Das, Parthasarathi and Wang, Guang Xing and Mita, Takashi and Lear, Martin J. and Hirama, Masahiro (2002) Diastereoselective additions of ethynyl Grignard reagent to erythrulose derivatives. Chemistry Letters, 31 (3). pp. 300-301. ISSN 0366-7022

Kotturi, Santosh R. and Somanadhan, Brinda and Ch’ng, Jun-Hong and Tan, Kevin S.-W. and Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Kotturi, Santosh R. and Tan, Jason S. and Lear, Martin J. (2009) A mild method for the protection of alcohols using a para-methoxybenzylthio tetrazole (PMB-ST) under dual acid–base activation. Tetrahedron Letters, 50 (37). pp. 5267-5269. ISSN 0040-4039

Koyama, Yasuhito and Lear, Martin J. and Yoshimura, Fumihiko and Ohashi, Isao and Mashimo, Tomoko and Hirama, Masahiro (2005) Efficient construction of the kedarcidin chromophore ansamacrolide. Organic Letters, 7 (2). pp. 267-270. ISSN 1523-7060

Lear, Martin J. and Hirama, Masahiro (1999) Convenient route to derivatives of the 2-deoxysugar subunits of the kedarcidin chromophore: L-mycarose and L-kedarosamine. Tetrahedron Letters, 40 (26). pp. 4897-4900. ISSN 0040-4039

Lear, Martin J. and Simon, Oliver and Foley, Timothy L. and Burkart, Michael D. and Baiga, Thomas J. and Noel, Joseph P. and DiPasquale, Antonio G. and Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Lear, Martin J. and Yoshimura, Fumihiko and Hirama, Masahiro (2001) A direct and efficient α-selective glycosylation protocol for the kedarcidin sugar, L-mycarose: AgPF6 as a remarkable activator of 2-deoxythioglycosides. Angewandte Chemie International Edition, 40 (5). pp. 946-949. ISSN 1433-7851

Liu, Xiang Hui and Song, Hong Yan and Ma, Xiao Hua and Lear, Martin J. and Chen, Yu Zong (2010) Virtual screening prediction of new potential organocatalysts for direct aldol reactions. Journal of Molecular Catalysis A: Chemical, 319 (1-2). pp. 114-118. ISSN 1381-1169

Miao, Ru and Gramani, Subramanian G. and Lear, Martin J. (2009) Stereocontrolled entry to the tricyclo[3.3.0]oxoheptane core of bielschowskysin by a [2+2] cycloaddition of an allene-butenolide. Tetrahedron Letters, 50 (15). pp. 1731-1733. ISSN ISSN

Moore, Jonathan C. and Davies, E. Stephen and Walsh, Darren A. and Sharma, Pallavi and Moses, John E. (2014) Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels–Alder reaction. Chemical communications, 50 (83). pp. 12523-12525. ISSN 1359-7345

Moorhouse, Adam D. and Spiteri, Christian and Sharma, Pallavi and Zloh, Mire and Moses, John E. (2011) Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5. Chemical Communications, 47 (1). pp. 230-232. ISSN 1359-7345

Ngai, Mun H. and Yang, Peng-Yu and Liu, Kai and Shen, Yuan and Wenk, Markus R. and Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

Ohashi, Isao and Lear, Martin J. and Yoshimura, Fumihiko and Hirama, Masahiro (2004) Use of polystyrene-supported DBU in the synthesis and α-selective glycosylation study of the unstable Schmidt donor of L-kedarosamine. Organic Letters, 6 (5). pp. 719-722. ISSN 1523-7060

Pasari, Sandip and Ismail, Shareef M. and Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters . ISSN ISSN

Powell, Kimberley J. and Han, Li-Chen and Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

Powell, Kimberley J. and Sharma, Pallavi and Richens, Joanna L. and Daviss, Benjamin M. and Moses, John E. and O'Shea, Paul (2012) Interactions of marine-derived γ-pyrone natural products with phospholipid membranes. Physical Chemistry Chemical Physics, 14 (42). pp. 14489-14491. ISSN 1463-9076

Rodríguez, Abimael D. and Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

Sharma, Pallavi and Griffiths, Nicholas and Moses, John E. (2008) Biomimetic synthesis and structural revision of tridachiahydropyrone. Organic Letters, 10 (18). pp. 4025-4027. ISSN 1523-7060

Sharma, Pallavi and Lygo, Barry and Williams, Lewis and Moses, John E. (2009) Biomimetic synthesis and structural reassignment of the tridachiahydropyrones. Journal of the American Chemical Society, 131 (16). pp. 5966-5972. ISSN 0002-7863

Sharma, Pallavi and Moorhouse, Adam D. and Moses, John E. (2011) Microwave enhanced tandem azidation-amidation of anilines. Synlett, 2011 (16). pp. 2384-2386. ISSN 0936-5214

Sharma, Pallavi and Moses, John E. (2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and click linker. Org. Lett., 12 (12). pp. 2860-2863. ISSN 1523-7060

Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN 0936-5214

Sharma, Pallavi and Powell, Kimberley J. and Burnley, James and Moses, John E. and Awaad, Amani S. (2011) Total synthesis of polypropionate derived y-pyrone natural products. Synthesis, 18 . pp. 2865-2892. ISSN 0039-7881

Sharma, Pallavi and Ritson, Dougal J. and Burnley, James and Moses, John E. (2011) A synthetic approach to Kingianin A based upon biosynthetic speculation. Chemical Communications, 47 (38). pp. 10605-10607. ISSN 1359-7345

Simon, Oliver and Reux, Bastien and La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Somanadhan, Brinda and Kotturi, Santosh R. and Yan Leong, Chung and Glover, Robert P. and Huang, Yicun and Flotow, Horst and Buss, Antony D. and Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

Song, Hong Y. and Ngai, Mun H. and Song, Zhen Y. and MacAry, Paul A. and Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520

Spiteri, Christian and Mason, Christopher and Zhang, Fengzhi and Ritson, Dougal J. and Sharma, Pallavi and Keeling, Steve and Moses, John E. (2010) An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne. Organic and Biomolecular Chemistry Articles, 8 (11). pp. 2537-2542. ISSN 1477-0520

Spiteri, Christian and Sharma, Pallavi and Zhang, Fengzhi and Macdonald, Simon J. F. and Keeling, Steve and Moses, John E. (2010) An improved synthesis of 1,2-benzisoxazoles: TBAF mediated 1,3-dipolar cycloaddition of nitrile oxides and benzyne. Chemical Communications, 46 (8). pp. 1272-1274. ISSN 1359-7345

Usuki, Toyonobu and Mita, Takashi and Lear, Martin J. and Das, Parthasarathi and Yoshimura, Fumihiko and Inoue, Masayuki and Hirama, Masahiro and Akiyama, Kimio and Tero-Kubota, Shozo (2004) Spin trapping of 13C-labeled p-benzynes generated by Masamune–Bergman cyclization of bicyclic nine-membered enediynes. Angewandte Chemie International Edition, 43 (39). pp. 5249-5253. ISSN 1433-7851

Yamada, Kei and Lear, Martin J. and Yamaguchi, Takaya and Yamashita, Shuji and Gridnev, Ilya D. and Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic total synthesis of cyanosporaside aglycons from a single enediyne precursor through site-selective p-benzyne hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

Yang, Eugene G. and Sekar, Karthik and Lear, Martin J. (2013) A macrolactonisation approach to the cembrane carbocycle of bielschowskysin. Tetrahedron Letters, 54 (33). pp. 4406-4408. ISSN 0040-4039

Yang, Peng-Yu and Liu, Kai and Ngai, Mun Hong and Lear, Martin J. and Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Yang, Peng-Yu and Liu, Kai and Zhang, Chongjing and Chen, Grace Y. J. and Shen, Yuan and Ngai, Mun Hong and Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

Yang, Peng-Yu and Wang, Min and Liu, Kai and Ngai, Mun Hong and Sheriff, Omar and Lear, Martin J. and Sze, Siu Kwan and He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

Yoshimura, Fumihiko and Lear, Martin J. and Ohashi, Isao and Koyama, Yasuhito and Hirama, Masahiro (2007) Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon. Chemical Communications (29). p. 3057. ISSN 1359-7345

Review

Lear, Martin J. and Hayashi, Yujiro (2013) Remote 1,6-stereocontrol by iminium-mediated organocatalytic events. [Review]

Book Section

Burnley, James and Ralph, Michael and Sharma, Pallavi and Moses, John E. (2011) Biomimetic electrocyclisation reactions towards polyketide-derived natural products. In: Biomimetic Organic Synthesis. Wiley-VCH, Weinheim. ISBN 9783527325801, 9783527634606

Conference or Workshop Item

Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain. (Unpublished)

Thesis

Lightfoot, Ian Peter and Colston, Belinda and Dahm, R (2000) Reductive destruction of chlorinated organics in molten salt. PhD thesis, De Montfort University.

This list was generated on Sun Apr 19 23:37:28 2015 BST.