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Items where Subject is "F160 Organic Chemistry"

JACS Subject (185)
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  - F160 Organic Chemistry (185)

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'click' ligand 1 1,4-Dithiane-2,5-diol, Heterocycles, Thiophene, Michael/Aldol reactions 2 2-Deoxy sugars 3-dipolar addition 3-dipolar cycloaddition 6-thiadiazines ?-Stacking interaction AIE Aggregation induced emission Ab initio and DFT calculations Ab initio structural calculations Acetone cyano hydrin Acridine-HSP90 Acyl ketene Aldol reaction Alkenyl nitrile Amidation Amide synthesis Amino acids Anitmalarial agents Anitproliferative activity Anthraquinonecarboxylic acid Anti-tumor activities Antibody labelling Antimicrobial Antiproliferative activity Aryl halide Asymmetric catalysis Asymmetric resolution Asymmetric synthesis Bead microarray Benzisoxazole Bezisoxazole Bielschowskysin Binding affinity screening Bio-target identification Bio-targeting Biology Biomedicine Biomimetic Synthesis Biomimetic synthesis Biomimicry Biomolecular identification Biosynthesis Biotarget identification Biotechnology Bismuth Brewster angle microscopy Brewster angle reflectometry Bulgecinine C-terminal fragment CCG CRYSTAL STRUCTURE Calix[4]arene Cambodia Caprolactam Carbon nitride Cembranes Chemical characterisation Chemical proteomics Chemical reagent Chemistry Chirality Chitinophaga Click Chemistry Click reaction Click-chemistry Computational chemistry Conjugate reduction Conjugated Polymer Convergent synthetic strategy Coupling reagents Cross-coupling Cross-coupling reaction Cryptophane Crystal engineering Cyanamide Cyanation Cycloaddition Cycloalkenes Cycloaromatization Cyclopropanation DMSO solvate DNA cleavage DNA sequence DNA-binding polyamides Dehydrofluorination/zincation Density functional theory Density functional theory (DFT) calculations Density functional theory calculations Deoxy sugars Detection of binding events Dieckmann cyclization Diels-Alder Dimer Diterpenes Donor-?-Acceptor Drug discovery Drug labelling Drug off-targets Drug resistance Dual catalysis Dye-Sensitized Solar Cells Dye-sensitized Solar Cells Dynamic atomic force microscopy Electrochemistry Electrocyclisation Electrocycllisation Enantiodivergent Enzymes Epoxidation reaction Erythrulose Falcitidin Fatty acid synthase Fluorescence Fluorescent immuno-affinity label Fluorescent labels Fluorescent sensing Fluorescent-labeled probes Free radical carbonylation Free radical chemistry Friedel-Crafts Furanocembranoid G-quadruplex Gas chromatography Gemini surfactants Globalisation Glycobiology Glycolipids Glycosylation Green chemistry Grignard addition Hairpin pyrrole-imidazole polyamides Hemolytic activity Hole Transporter Homogenous catalysis Homolytic substitution Hybrid solar cell Hydrazone Hydrogen Bonding Hyperpolarisation Imine Immobilisation chemistry Immuno-affinity screening Inositol Insulating surfaces Interfacial modification Intermolecular interactions Intermolecular radical addition Intramolecular Intramolecular cyclisation Iron Isotope labelling JCNotOpen JCOpen Kinetics Kingianin A Knoevenagel reaction L-allo-enduracididine Lactam Lactam antibiotic Lactate dehydrogenase Langmuir monolayers Laser ablation Lead discovery Lipid II MIRC Macrocyclisation Malaria Malaria detection Maleimide reagents Mechanism Mechanochemistry Merocyanine Merocyanines Metal-free organic dye Metathesis reactions Methodology Mevalonate Michael addition Mode-of-action Molecular Conformation Molecular Imaging Molecular structure N-terminal fragment NMR NMR Spectroscopy NMR spectroscopy NMR study Natural Product Natural Products Natural enediynes Natural product Natural products Negishi coupling Nitrile Oxide NotOAChecked Odor activity value Olfractometry Organic Dye Organic Sensitizer Organic Sensitizers Organic methods Organic synthesis Organic vapor sorption Organocatalysis Organocatalyst Organohalogens Orlistat Oxadiazol-5-imine Oxazoles P3HT Palladium catalysis Peptide synthesis Peptides Peptides. PEG Photo-switches Photocatalysis Photochemistry Plasmodium Poly(3-hexylthiophene) Polyketide Polypropionate Polythiophene Protecting groups Protein tyrosine kinases QMB measurement Radical Cation Radical chemistry Radical cyclization Radical reaction Reaction kinetics Reduction SNAP-tag technology Selenium Self assembly Self-assembled monolayers Self-assembly Sensitized Solar Cells Serine Singapore Single electron transfer Singlet Oxygen Smart optical linkers Solid phase Solid-State Solvent-free synthesis Sonogashira Spiropyran Spiropyran monolayers Spiropyrans Stereoisomer synthesis Stereoselective Stereoselective glycosylation Structure-Activity Relationship Sulfinamides Sulfinates Supramolecular chemistry Sustainable chemistry Teixobactins Telomerase Tetraols Tetrapeptide Total synthesis Total synthesis studies Transannular ring-opening Triazole Trifluormethyl Triphenylamine Tyrophostins Tyrphostins Valerolactam Virtual screening Wittig synthesis X-ray diffraction X-ray structure X-ray studies X-ray study Xenon Zirconium [3+2] cycloaddition addition reactions alkyl chain alkyne silane amidation amide amino acid anisole anti-tumour agents antibiotics antibiotics•antimicrobial resistance•drug development•lipid II•MRSA•Mycobacterium tuberculosis •peptides•Teixobactin•VRE antimalarial antimicrobial activity antiparasitic agents arsenic artificial receptor asymmetric induction azide benzenoids benzothiophen benzyne bioassay bioimaging bioisotere biomimetic synthesis bismuth bisphenol bisphenols bmjdoi bmjgoldcheck bromine bromine interactions bulk insulator calcite calixarene caprolactam catalysis catenanes; interlocked molecules; links; supramolecular chemistry; template synthesis chemical biology chemical proteomics chemisorption chlorinated organics click chemistry computational modeling conformational analysis conformational studies conglomerate conjugate reduction conjugation covalent assembly cyanamide; synthesis; aminocyanation; cycloaddition; electrophilic cyanation; radical reaction; coordination chemistry cyanoacetic acid cyclization cyclophane cyclopropane dimerization diradicals drug discovery drug synthesis electrocyclisation electronic decoupling enediynes epigenetics esterification excimer falcipain falcitidin fluorescence fluorescent dye fluorescent probes fluorescophane gamma pyrone geomorphology glycolysis halogen bonding halogen interactions hazardous waste heteroaromatic compound heterocycle heterocycles heterogeneous catalysis homolytic substitution host-guest hydrogen storage hyperpolarisation iminium inclusion compound indole alkaloid iodination iodine irradiation isometricity comparison isostructurality kinetics lactam lactams larvicidal layered material macrocycle macrocyclic compound malaria materials chemistry metal-organic frameworks methodology methyllysine microparticles mitralactonine mixed-linker mixtures molecular electronics molecular overlay calculation molecular recognition mollusc monochlorination morphotropism mosquito myxobacteria oapaid on-surface synthesis on-surface synthesis on insulators organic chemistry organic synthesis organocatalysis orlistat p-Benzynes peptide formation phochemical photochemical photosensitizer polypropionate proteomics pyrene radical reactivity reagentless assay reductive destruction rhodanine-3-acetic acid ring closing metathesis sedimentary organic material self assembly self-defence sensor active material singlet oxygen solid state solvent inclusion sulfur sulphur supramolecular chemistry synthon teixobactin tetrapeptide tetraphenylethene thio-acid total synthesis tridachiahydropyrone trimesic acid homologue trypanosomiasis umpolung valerolactam visible light photosensitizer water wheel-and-axle host

Number of items at this level: 688.

'click' ligand

Cousins, Alex R. O., Ritson, Dougal, Sharma, Pallavi, Stevens, Malcolm F. G., Moses, John E. and Searle, Mark S. (2014) Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences. Chemical Communications, 50 . pp. 15202-15205. ISSN 1359-7345

1

Bhat, Shreesha V., Robinson, David, Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN 1523-7060

Broumidis, Emmanouil, Thomson, Christopher G., Gallagher, Brendan, Sotorríos, Lia, McKendrick, Kenneth G., Macgregor, Stuart A., Paterson, Martin J., Lovett, Janet E., Lloyd, Gareth O., Rosair, Georgina M., Kalogirou, Andreas S., Koutentis, Panayiotis A. and Vilela, Filipe (2023) The Photochemical Mediated Ring Contraction of 4H-1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazol-3(2H)-one 1-Oxides. Organic letters, 25 . pp. 6907-6912. ISSN 1523-7060

Spiteri, Christian, Mason, Christopher, Zhang, Fengzhi, Ritson, Dougal J., Sharma, Pallavi, Keeling, Steve and Moses, John E. (2010) An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne. Organic and Biomolecular Chemistry Articles, 8 (11). pp. 2537-2542. ISSN 1477-0520

Spiteri, Christian, Sharma, Pallavi, Zhang, Fengzhi, Macdonald, Simon J. F., Keeling, Steve and Moses, John E. (2010) An improved synthesis of 1,2-benzisoxazoles: TBAF mediated 1,3-dipolar cycloaddition of nitrile oxides and benzyne. Chemical Communications, 46 (8). pp. 1272-1274. ISSN 1359-7345

1,4-Dithiane-2,5-diol, Heterocycles, Thiophene, Michael/Aldol reactions

Francesco, Zamberlan, Anna, Fantinati and Claudio, Trapella (2018) 1,4‐Dithiane‐2,5‐diol: An Attractive Platform for the Synthesis of Sulfur Containing Functionalized Heterocycles. European Journal of Organic Chemistry, 2018 (25). pp. 3248-3264. ISSN 1434-193X

2 2-Deoxy sugars

Lear, Martin J. and Hirama, Masahiro (1999) Convenient route to derivatives of the 2-deoxysugar subunits of the kedarcidin chromophore: L-mycarose and L-kedarosamine. Tetrahedron Letters, 40 (26). pp. 4897-4900. ISSN 0040-4039

Lear, Martin J., Yoshimura, Fumihiko and Hirama, Masahiro (2001) A direct and efficient α-selective glycosylation protocol for the kedarcidin sugar, L-mycarose: AgPF6 as a remarkable activator of 2-deoxythioglycosides. Angewandte Chemie International Edition, 40 (5). pp. 946-949. ISSN 1433-7851

3-dipolar addition

3-dipolar cycloaddition

6-thiadiazines

?-Stacking interaction

Gruber, Tobias, Helas, Stefanie F., Seichter, Wilhelm and Weber, Edwin (2010) X-ray crystal structures of two solvent complexes involving positionally isomeric 9,10-anthraquinonecarboxylic acids and DMSO. Structural Chemistry, 21 (5). pp. 1079-1083. ISSN 1040-0400

AIE Aggregation induced emission

Broumidis, Emmanouil, Jones, Gareth, Koyioni, Maria, Kourtellaris, Andreas, Lloyd, Gareth, Marques-Hueso, Jose, Koutentis, Panayiotis and Vilela, Filipe (2021) 8,8'-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)bis(quinolin-4(1H)-one): A Twisted Photosensitizer with AIE Properties. RSC Advances, 11 . pp. 29102-29107. ISSN 2046-2069

Ab initio and DFT calculations

Kyne, Sara and Schiesser, C. H. (2009) Ab initio studies of carbonyl radical additions to hydrazone systems. Australian Journal of Chemistry, 62 (7). pp. 728-733. ISSN 0004-9425

Ab initio structural calculations

Kyne, S. H., Schiesser, C. H. and Matsubara, H. (2008) Multiorbital interactions during acyl radical addition reactions involving imines and electron-rich olefins. Journal of Organic Chemistry, 73 (2). pp. 427-434. ISSN 0022-3263

Kyne, S. H., Schiesser, C. H. and Matsubara, H. (2011) An ab initio and DFT study of radical addition reactions of imidoyl and thioyl radicals to methanimine. Organic and Biomolecular Chemistry, 9 (9). pp. 3217-3224. ISSN 1477-0520

Acetone cyano hydrin

Powell, Kimberley J., Han, Li-Chen, Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

Acridine-HSP90

Roe, S., Gunaratnam, M., Spiteri, C., Sharma, Pallavi, Alharthy, R. D., Neidle, S. and Moses, J. E. (2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Organic and Biomolecular Chemistry, 13 . pp. 8500-8504. ISSN 1477-0520

Acyl ketene

Yang, Eugene G., Sekar, Karthik and Lear, Martin J. (2013) A macrolactonisation approach to the cembrane carbocycle of bielschowskysin. Tetrahedron Letters, 54 (33). pp. 4406-4408. ISSN 0040-4039

Aldol reaction

Liu, Xiang Hui, Song, Hong Yan, Ma, Xiao Hua, Lear, Martin J. and Chen, Yu Zong (2010) Virtual screening prediction of new potential organocatalysts for direct aldol reactions. Journal of Molecular Catalysis A: Chemical, 319 (1-2). pp. 114-118. ISSN 1381-1169

Alkenyl nitrile

Powell, Kimberley J., Han, Li-Chen, Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

Amidation

Li, Jing, Lear, Martin, Kwon, Eunsang and Hayashi, Yujiro (2016) Mechanism of oxidative amidation of nitroalkanes with oxygen and amine nucleophiles using electrophilic iodine. Chemistry - A European Journal, 22 (16). pp. 5538-5542. ISSN 0947-6539

Lloyd, Gareth O., Broumidis, Emmanouil, Jones, Mary C. and Vilela, Filipe (2020) Mechanochemical Synthesis of N-Aryl Amides from O-Protected Hydroxamic Acids. ChemPlusChem, 85 (8). pp. 1754-1761. ISSN 2192-6506

Amide synthesis

Li, Jing, Lear, Martin and Hayashi, Yujiro (2016) Sterically demanding oxidative amidation of alpha-substituted malononitriles with amines using O2. Angewandte Chemie International Edition, 128 (31). pp. 9060-9064. ISSN 1433-7851

Wang, Xiaonan, Xu, Silong, Tang, Yuhai, Lear, Martin, Wanxiao, He and Li, Jing (2023) Nitroalkanes as Thioacyl Equivalents to Access Thioamides and Thiopeptides. Nature Communications, 14 . p. 4626. ISSN 2041-1723

Amino acids

Ghosh, Shibaji K., Somanadhan, Brinda, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2012) Absolute configuration and total synthesis of a novel antimalarial lipopeptide by the de novo preparation of chiral nonproteinogenic amino acids. Organic Letters, 14 (6). pp. 1560-1563. ISSN 1523-7060

Anitmalarial agents

Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S. and Lear, Martin J. (2014) Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads. Tetrahedron Letters, 55 (11). pp. 1949-1951. ISSN 0040-4039

Anitproliferative activity

Brunton, V. G., Lear, M., Robins, D. J., Williamson, S. and Workman, P. (1994) Synthesis and antiproliferative activity of tyrphostins containing heteroaromatic moieties. Anti-Cancer Drug Design, 9 (4). pp. 291-309. ISSN 0266-9536

Anthraquinonecarboxylic acid

Anti-tumor activities

Yang, Peng-Yu, Liu, Kai, Ngai, Mun Hong, Lear, Martin J., Wenk, Markus R. and Yao, Shao Q. (2010) Activity-based proteome profiling of potential cellular targets of Orlistat - an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society, 132 (2). pp. 656-666. ISSN 0002-7863

Antibody labelling

Song, Hong Y., Ngai, Mun H., Song, Zhen Y., MacAry, Paul A., Hobley, Jonathan and Lear, Martin J. (2009) Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & Biomolecular Chemistry, 7 (17). pp. 3400-3406. ISSN 1477-0520

Antimicrobial

Parmar, Anish, Iyer, Abhishek, Lloyd, Daniel, Vincent, Charlotte, Prior, Stephen, Taylor, Edward and Singh, Ishwar (2017) Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres. Chemical Communications, 53 (55). pp. 7788-7791. ISSN 1359-7345

Antiproliferative activity

Brunton, V. G., Lear, M., McKeown, P., Robins, D. J. and Workman, P. (1996) Synthesis and antiproliferative activity of tyrphostins containing quinoline moieties. Anti-Cancer Drug Design, 11 (6). pp. 463-483. ISSN 0266-9536

Aryl halide

Kyne, Sara H., Percy, Jonathon M., Pullin, Robert D. C., Redmond, Joanna M. and Wilson, Peter G. (2011) One-pot near-ambient temperature syntheses of aryl(difluoroenol) derivatives from trifluoroethanol. Organic and Biomolecular Chemistry, 9 (24). pp. 8328-8339. ISSN 14770520

Asymmetric catalysis

Asymmetric resolution

Ali, Asif, Wenk, Markus R. and Lear, Martin J. (2009) Total synthesis of a fully lipidated form of phosphatidyl-myo-inositol dimannoside (PIM-2) of Mycobacterium tuberculosis. Tetrahedron Letters, 50 (40). pp. 5664-5666. ISSN 0040-4039

Asymmetric synthesis

Hayashi, Yujiro, Shomura, Hiroki, Xu, Qianqian, Lear, Martin and Sato, Itaru (2015) Asymmetric aldol reaction of α,α-disubstituted acetaldehydes catalyzed by Ddphenylprolinol silyl ether for the construction of quaternary stereogenic centers. European Journal of Organic Chemistry, 20 . pp. 4316-4319. ISSN 1434-193X

Bead microarray

National University of Singapore (2013) A microparticle assembly. WO2013176625 A1.

Benzisoxazole

Bezisoxazole

Bielschowskysin

Miao, Ru, Gramani, Subramanian G. and Lear, Martin J. (2009) Stereocontrolled entry to the tricyclo[3.3.0]oxoheptane core of bielschowskysin by a [2+2] cycloaddition of an allene-butenolide. Tetrahedron Letters, 50 (15). pp. 1731-1733. ISSN ISSN

Yang, Eugene G., Sekar, Karthik and Lear, Martin J. (2013) A macrolactonisation approach to the cembrane carbocycle of bielschowskysin. Tetrahedron Letters, 54 (33). pp. 4406-4408. ISSN 0040-4039

Binding affinity screening

Rodríguez, Abimael D., Lear, Martin J. and La Clair, James J. (2008) Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol. Journal of the American Chemical Society, 130 (23). pp. 7256-7258. ISSN 0002-7863

Bio-target identification

Lear, Martin (2011) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins [ACP Tour, Japan]. In: Asia Core Program Lectureship Tour of Japan, 18-22 Dec 2011, Nagoya, Tokyo, and Tohoku, Japan.

Bio-targeting

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Biology

Lear, Martin J., Salmons, Brian, Gunzburg, Walter H. and Dangerfield, John A. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4 (2). pp. 179-185. ISSN ISSN

Biomedicine

Lear, Martin J., Salmons, Brian, Gunzburg, Walter H. and Dangerfield, John A. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4 (2). pp. 179-185. ISSN ISSN

Biomimetic Synthesis

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin, Hirai, Keiichiro, Yamada, Kei, Takahashi, Ryo and Hirama, Masahiro (2014) Total synthesis and biomimetic studies of nine-membered enediynes. In: CRC International Symposium: Synthesis and Applications of Functional Molecules and Materials Utilizing Biomolecules as a Motif, September 30, 2014, Catalytic Research Center, Hokkaido University, Japan.

Sharma, Pallavi (2016) Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design . ISSN 1381-6128

Sharma, Pallavi, Powell, Kimberley J., Burnley, James, Moses, John E. and Awaad, Amani S. (2011) Total synthesis of polypropionate derived y-pyrone natural products. Synthesis, 18 . pp. 2865-2892. ISSN 0039-7881

Sharma, Pallavi, Ritson, Dougal J., Burnley, James and Moses, John E. (2011) A synthetic approach to Kingianin A based upon biosynthetic speculation. Chemical Communications, 47 (38). pp. 10605-10607. ISSN 1359-7345

Biomimetic synthesis

Burnley, James, Ralph, Michael, Sharma, Pallavi and Moses, John E. (2011) Biomimetic electrocyclisation reactions towards polyketide-derived natural products. In: Biomimetic Organic Synthesis. Wiley-VCH, Weinheim. ISBN 9783527325801, 9783527634606

Simon, Oliver, Reux, Bastien, La Clair, James J. and Lear, Martin J. (2010) Total synthesis confirms laetirobin as a formal Diels-Alder adduct. Chemistry - An Asian Journal, 5 (2). pp. 342-351. ISSN 1861-4728

Biomimicry

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin, Reux, Bastien and Sekar, Karthik (2012) Chemical synthesis, modification and mimicry of the GPI anchor. In: GPI membrane anchors: the much needed link. Bentham Science Publishers Ltd, pp. 64-82. ISBN 9781608051236

Biomolecular identification

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Biosynthesis

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Biotarget identification

Biotechnology

Lear, Martin J., Salmons, Brian, Gunzburg, Walter H. and Dangerfield, John A. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4 (2). pp. 179-185. ISSN ISSN

Bismuth

Eey, Stanley T.-C. and Lear, Martin J. (2010) A bismuth(III)-catalyzed Friedel−Crafts cyclization and stereocontrolled organocatalytic approach to (−)-platensimycin. Organic Letters, 12 (23). pp. 5510-5513. ISSN 1523-7060

Brewster angle microscopy

Gorelik, Sergey, Hongyan, Song, Lear, Martin J. and Hobley, Jonathan (2010) Transient Brewster angle reflectometry of spiropyran monolayers. Photochemical and Photobiological Sciences, 9 (2). pp. 141-151. ISSN 1474-905X

Li, Y., Song, H. Y., Lear, M. J., Gorelik, S., Tomczak, N. and Hobley, J. (2008) Optical detection of photo-activated protein adsorption using Brewster angle microscopy. In: PhotonicsGlobal@Singapore, 2008. IPGC 2008, 8-11 Dec 2008, Singapore.

Brewster angle reflectometry

Siebenhofer, Bernhard, Gorelik, Sergey, Lear, Martin J., Song, Hong Yan, Nowak, Christoph and Hobley, Jonathan (2013) Transient absorption spectroscopy on spiropyran monolayers using nanosecond pump–probe Brewster angle reflectometry. Photochemical & Photobiological Sciences, 12 (5). pp. 848-853. ISSN 1474-905X

Bulgecinine

Chavan, Subhash P, Praveen, Cherukupally, Sharma, Pallavi and Kalkote, U. R. (2005) An efficient stereoselective synthesis of (2S,4S,5R)-(-)- and (2R,4R,5S)-(+)-bulgecinine. Tetrahedron Letters, 46 (3). pp. 439-441. ISSN 0040-4039

C-terminal fragment

Fallows, Andrew J., Singh, Ishwar, Dondi, Ruggero, Cullis, Paul M. and Burley, Glenn A. (2014) Highly efficient synthesis of DNA-binding polyamides using a convergent fragment-based approach. Organic Letters, 16 (17). pp. 4654-4657. ISSN 1523-7060

CCG

Chavan, Subhash P., Sharma, Pallavi, Sivappa, Rasapalli, Bhadbhade, Mohan B., Gonnade, Rajesh G. and Kalkote, Uttam R. (2003) Enantioselective synthesis of L-CCG-I. Journal of the American Chemical Society, 68 (17). pp. 6871-6819. ISSN 0002-7863

CRYSTAL STRUCTURE

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) Crystal behavior of lactams and the missing link δ-valerolactam. In: BCA Spring Meeting 2018, 26th-29th March 2018, Coventry.

Calix[4]arene

Hanauer, Thomas, Hopkinson, Richard J, Patel, Kamel, Li, Yu, Correddu, Danilo, Kawamura, Akane, Sarojini, Vijay, Leung, Ivanhoe K. H. and Gruber, Tobias (2017) Selective recognition of the di/trimethylammonium motif by an artificial carboxycalixarene receptor. Organic & Biomolecular Chemistry, 15 . pp. 1100-1105. ISSN 1477-0520

Cambodia

Magnone, Daniel, Richards, Laura A., Polya, David A., Bryant, Charlotte, Jones, Merren and van Dongen, Bart E. (2017) Biomarker-indicated extent of oxidation of plant-derived organic carbon (OC) in relation to geomorphology in an arsenic contaminated Holocene aquifer, Cambodia. Scientific Reports, 7 (1). p. 13093. ISSN 2045-2322

Caprolactam

Gruber, Tobias (2016) From artificial antibodies to bridged caprolactams. In: Invited Lecture hosted by the School of Pharmacy, University of East Anglia., 12 January 2016, Norwich.

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2019) Does the exception prove the rule? - A comparative study of supramolecular synthons in a series of lactam esters. Cryst. Growth Des. . ISSN 1528-7483

Carbon nitride

Vijeta, Arjun, Casadevall, Carla, Roy, Souvik and Reisner, Erwin (2021) Visible-light Promoted C–O Bond Formation with an Integrated Carbon Nitride-Nickel Heterogeneous Photocatalyst. Angewandte Chemie International Edition, 60 (15). pp. 8494-8499. ISSN 1433-7851

Cembranes

Chemical characterisation

Lear, Martin J., Simon, Oliver, Foley, Timothy L., Burkart, Michael D., Baiga, Thomas J., Noel, Joseph P., DiPasquale, Antonio G., Rheingold, Arnold L. and La Clair, James J. (2009) Laetirobin from the parasitic growth of Laetiporus sulphurous on Robinia pseudoacacia. Journal of Natural Products, 72 (11). pp. 1980-1987. ISSN 0163-3864

Chemical proteomics

Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.

Ngai, Mun H., Yang, Peng-Yu, Liu, Kai, Shen, Yuan, Wenk, Markus R., Yao, Shao Q. and Lear, Martin J. (2010) Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications, 46 (44). p. 8335. ISSN 1359-7345

Chemical reagent

Kotturi, Santosh R., Tan, Jason S. and Lear, Martin J. (2009) A mild method for the protection of alcohols using a para-methoxybenzylthio tetrazole (PMB-ST) under dual acid–base activation. Tetrahedron Letters, 50 (37). pp. 5267-5269. ISSN 0040-4039

Chemistry

Lear, Martin J., Salmons, Brian, Gunzburg, Walter H. and Dangerfield, John A. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4 (2). pp. 179-185. ISSN ISSN

Chirality

Gruber, Tobias, Gruner, Margit, Fischer, Conrad, Seichter, Wilhelm, Bombicz, Petra and Weber, Edwin (2010) Conformational behaviour and first crystal structures of a calix[4]arene featuring a laterally positioned carboxylic acid function in unsolvated and solvent-complexed forms. New Journal of Chemistry, 34 (2). p. 250. ISSN 1144-0546

Chitinophaga

Somanadhan, Brinda, Kotturi, Santosh R., Yan Leong, Chung, Glover, Robert P., Huang, Yicun, Flotow, Horst, Buss, Antony D., Lear, Martin J. and Butler, Mark S. (2013) Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2. The Journal of Antibiotics, 66 (5). pp. 259-264. ISSN 0021-8820

Click Chemistry

Click reaction

Sharma, Pallavi and Moses, John E. (2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and click linker. Org. Lett., 12 (12). pp. 2860-2863. ISSN 1523-7060

Click-chemistry

Moorhouse, Adam D., Spiteri, Christian, Sharma, Pallavi, Zloh, Mire and Moses, John E. (2011) Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5. Chemical Communications, 47 (1). pp. 230-232. ISSN 1359-7345

Computational chemistry

MacDougall, P .E., Aitken, H. M., Scammells, P. J., Kavanagh, Y., Kyne, S. H. and Schiesser, C. H. (2012) 7-Selenabicyclo2.2.1heptane. Chemical Communications, 48 (73). pp. 9126-9128. ISSN 1359-7345

Conjugate reduction

Conjugated Polymer

Zhang, Wei, Fang, Zhen, Su, Mingjuan, Saeys, Mark and Liu, Bin (2009) A triphenylamine-based conjugated polymer with donor-π-acceptor architecture as organic sensitizer for dye-sensitized solar cells. Macromolecular Rapid Communications, 30 (18). pp. 1533-1537. ISSN 1022-1336

Convergent synthetic strategy

Coupling reagents

Cross-coupling

Cross-coupling reaction

Cryptophane

Zamberlan, Francesco, Lesbats, Clémentine, Rogers, Nicola J., Krupa, James L., Pavlovskaya, Galina E., Thomas, Neil R., Faas, Henryk M. and Meersmann, Thomas (2015) Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer. ChemPhysChem, 16 (11). pp. 2294-2298. ISSN 1439-4235

Crystal engineering

Fischer, Conrad, Gruber, Tobias, Eissmann, Diana, Seichter, Wilhelm and Weber, Edwin (2011) Unusual behavior of a calix[4]arene featuring the coexistence of basic cone and 1,2-alternate conformations in a solvated crystal. Crystal Growth & Design, 11 (5). pp. 1989-1994. ISSN 1528-7483

Fischer, Conrad, Gruber, Tobias, Seichter, Wilhelm, Schindler, Diana and Weber, Edwin (2008) 5,11,17,23-Tetra-tert-butyl-25,26,27,28-tetramethoxycalix[4]arene dichloromethane hemisolvate. Acta Crystallographica Section E: Structure Reports Online, 64 (4). o673-o673. ISSN 0365-110X

Fischer, Conrad, Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2007) 5,11,17,23-Tetra-tert-butyl-25,26,27,28-tetramethoxycalix[4]arene tetrahydrofuran solvate. Acta Crystallographica Section E: Structure Reports Online, 63 (12). o4572-o4573. ISSN 0365-110X

Fischer, Conrad, Gruber, Tobias, Seichter, Wilhelm, Weber, Edwin and Ibragimov, Bakhtiyar T. (2008) N-Cyclododecyl-5-(dimethylamino)naphthalene-1-sulfonamide. Acta Crystallographica Section E: Structure Reports Online, 64 (7). o1204. ISSN 0365-110X

Gruber, Tobias, Eissmann, Frank, Seichter, Wilhelm and Weber, Edwin (2010) 25-Allyloxy-5,11,17,23-tetra-tert-butyl-26,27,28-trihydroxycalix[4]arene chloroform disolvate. Acta Crystallographica Section C: Crystal Structure Communications, 66 (7). o334-o336. ISSN 0365-110X

Gruber, Tobias, Eissmann, Frank, Weber, Edwin and Schüürmann, Gerrit (2011) 1-Methyl-4-(4-nitrobenzoyl)pyridinium perchlorate. Acta Crystallographica Section E: Structure Reports Online, 67 (9). o2542-o2543. ISSN 0365-110X

Gruber, Tobias, Schofield, Christopher J. and Thompson, Amber L. (2012) 3-Methoxy-3-oxopropanaminium chloride. Acta Crystallographica Section E: Structure Reports Online, 68 (3). o595. ISSN 0365-110X

Gruber, Tobias, Schofield, Christopher J. and Thompson, Amber L. (2012) Methyl 6-amino-6-oxohexanoate. Acta Crystallographica Section E: Structure Reports Online, 68 (3). o593-o594. ISSN 0365-110X

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2010) 1-(Hydroxymethyl)pyrene. Acta Crystallographica Section E: Structure Reports Online, 66 (2). o443. ISSN 0365-110X

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2007) Crystal structure of 25,26,27,28-tetrabenzyloxy-5,11,17,23-tert-butylcalix- [4]arene, C72H80O4. Zeitschrift für Kristallographie - New Crystal Structures, 222 (3). pp. 222-224. ISSN 1433-7266

Münch, Alexander S., Katzsch, Felix, Gruber, Tobias and Mertens, Florian O.R.L. (2014) Spectroscopic, thermal and single crystal structure investigations of 2-bromotrimesic acid and its trimethyl ester analogue. Journal of Molecular Structure, 1074 . pp. 542-548. ISSN 0022-2860

Cyanamide

Cyanation

Powell, Kimberley J., Han, Li-Chen, Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

Cycloaddition

Cycloalkenes

Nelson, D. J., Ashworth, I. W., Hillier, I. H., Kyne, S. H., Pandian, S., Parkinson, J. A., Percy, J. M., Rinaudo, G. and Vincent, M. A. (2011) Why is RCM favoured over dimerisation? Predicting and estimating thermodynamic effective molarities by solution experiments and electronic structure calculations. Chemistry - A European Journal, 17 (46). pp. 13087-13094. ISSN 0947-6539

Cycloaromatization

Hirama, Masahiro, Akiyama, Kimio, Das, Parthasarathi, Mita, Takashi, Lear, Martin J., Iida, Kyo-ichiro, Sato, Itaru, Yoshimura, Fumihiko, Usuki, Toyonobu and Tero-Kubota, Shozo (2006) Direct observation of ESR spectra of bicyclic nine-membered enediynes at ambient temperature. Heterocycles, 69 (1). pp. 83-89. ISSN 0385-5414

Cyclopropanation

LI, Jing, Lear, Martin and Hayashi, Yujiro (2021) Direct Cyclopropanation of α‐Cyano β‐Aryl Alkanes by Light Mediated Single Electron Transfer between Donor‐Acceptor Pairs. Chemistry - A European Journal, 27 (19). pp. 5901-5905. ISSN 0947-6539

DMSO solvate

DNA cleavage

Kobayashi, Shoji, Ashizawa, Shukuko, Takahashi, Yusuke, Sugiura, Yukio, Nagaoka, Makoto, Lear, Martin J. and Hirama, Masahiro (2001) The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage. Journal of the American Chemical Society, 123 (45). pp. 11294-11295. ISSN 0002-7863

DNA sequence

DNA-binding polyamides

Dehydrofluorination/zincation

Density functional theory

Kyne, S. H., Miles, J. A. L., Percy, J. M. and Singh, K. (2012) Executing and rationalizing the synthesis of a difluorinated analogue of a ring-expanded calystegine B2. Journal of Organic Chemistry, 77 (2). pp. 991-998. ISSN 0022-3263

Kyne, Sara, Schiesser, Carl H. and Matsubara, Hiroshi (2007) Multi-component orbital interactions during oxyacyl radical addition reactions involving imines and electron-rich olefins. Organic & Biomolecular Chemistry, 5 (24). pp. 3938-3943. ISSN 1477-0520

Density functional theory (DFT) calculations

Richter, Antje, Floris, Andrea, Bechstein, Ralf, Kantorovich, Lev and Kühnle, Angelika (2018) On-surface synthesis on a bulk insulator surface. Journal of Physics: Condensed Matter, 30 (13). pp. 1-15. ISSN 0953-8984

Density functional theory calculations

Kyne, Sara H., Aitken, Heather M., Schiesser, Carl H., Lacote, Emmanuel, Malacria, Max, Ollivier, Cyril and Fensterbank, Louis (2011) Intramolecular homolytic substitution of sulfinates and sulfinamides: a computational study. Organic and Biomolecular Chemistry, 9 (9). pp. 3331-3337. ISSN 1477-0520

Deoxy sugars

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Detection of binding events

National University of Singapore (2013) A microparticle assembly. WO2013176625 A1.

Dieckmann cyclization

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) Facile synthesis and mechanistic investigations of bicyclic oxo-gamma-lactams from simple caprolactams. In: ORCHEM, 10th-12th September 2018, Berlin.

Diels-Alder

Chavan, Subhash P., Sharma, Pallavi, Ramakrishna, G. and Thakkar, Mahesh (2003) Iodine as an efficient catalyst in ionic Diels–Alder reactions of α,β-unsaturated acetals. Tetrahedron Letters, 44 (14). pp. 3001-3003. ISSN 0040-4039

Moore, Jonathan C., Davies, E. Stephen, Walsh, Darren A., Sharma, Pallavi and Moses, John E. (2014) Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels–Alder reaction. Chemical communications, 50 (83). pp. 12523-12525. ISSN 1359-7345

Dimer

Sharma, Pallavi (2016) Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design . ISSN 1381-6128

Diterpenes

Lear, Martin (2016) Synthetic ventures into the furanocembranes: bielschowskysin and beyond. In: Lecture Tour, January 2016, Tokyo University, Tohoku University, Kyushu University, 5-22 January 2016, Japan.

Donor-?-Acceptor

Drug discovery

Lear, Martin (2012) Total synthesis and drug pursuits: laetirobins, lipstatins, platensimycins. In: ZiNG Natural Products Conference 2012: Natural Products Synthesis and Biosynthesis, 10 - 13 February 2012, Lanzarote, Spain.

Drug labelling

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Drug off-targets

Drug resistance

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Dual catalysis

Dye-Sensitized Solar Cells

Cai, Liping, Tsao, Hoi Nok, Zhang, Wei, Wang, Long, Xue, Zhaosheng, Grätzel, Michael and Liu, Bin (2013) Organic sensitizers with bridged triphenylamine donor units for efficient dye-sensitized solar cells. Advanced Energy Materials, 3 (2). pp. 200-205. ISSN 1614-6832

Dye-sensitized Solar Cells

Warnan, Julien, Pellegrin, Yann, Blart, Errol, Odobel, Fabrice, Zhang, Wei, Liu, Bin, Babu, Veluru Jagadeesh and Ramakrishna, Seeram (2011) Application of poly(3-hexylthiophene) functionalized with an anchoring group in dye-sensitized solar cells. Macromolecular Rapid Communications, 32 (15). pp. 1190-1194. ISSN 1022-1336

Dynamic atomic force microscopy

Electrochemistry

Kyne, Sara H., Clémancey, Martin, Blondin, Geneviève, Derat, Etienne, Fensterbank, Louis, Jutand, Anny, Lefèvre, Guillaume and Ollivier, Cyril (2018) Elucidating dramatic ligand effects on SET processes: iron hydride versus Iron borohydride catalyzed reductive radical cyclization of unsaturated organic halides. Organometallics, 37 (5). pp. 761-771. ISSN 0276-7333

Kyne, Sara H., Lévêque, Christophe, Zheng, Shiwen, Fensterbank, Louis, Jutand, Anny and Ollivier, Cyril (2016) Iron(II) catalyzed reductive radical cyclization reactions of bromoacetals in the presence of NaBH4: optimization studies and mechanistic insights. Tetrahedron, 72 (48). 7727 - 7737. ISSN 0040-4020

Electrocyclisation

Electrocycllisation

Enantiodivergent

Ghosh, Shibaji K., Butler, Mark S. and Lear, Martin J. (2012) Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters, 53 (22). pp. 2706-2708. ISSN 0040-4039

Enzymes

Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana and Zanda, Matteo (2017) Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H NMR spectroscopy. Bioorganic & Medicinal Chemistry, 25 (10). pp. 2730-2742. ISSN 0968-0896

Epoxidation reaction

Erythrulose

Kobayashi, Shoji, Das, Parthasarathi, Wang, Guang Xing, Mita, Takashi, Lear, Martin J. and Hirama, Masahiro (2002) Diastereoselective additions of ethynyl Grignard reagent to erythrulose derivatives. Chemistry Letters, 31 (3). pp. 300-301. ISSN 0366-7022

Falcitidin

Fatty acid synthase

Fluorescence

Gruber, Tobias, Fischer, Conrad, Felsmann, Marika, Seichter, Wilhelm and Weber, Edwin (2009) Calix[4]arenes featuring a direct lower rim attachment of dansyl groups. Synthesis, fluorescence properties and first report on crystal structures. Organic & Biomolecular Chemistry, 7 (23). pp. 4904-4917. ISSN 1477-0520

Fluorescent immuno-affinity label

Fluorescent labels

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Fluorescent sensing

National University of Singapore (2013) A microparticle assembly. WO2013176625 A1.

Fluorescent-labeled probes

Free radical carbonylation

Kyne, S. H., Lin, C. Y., Ryu, I., Coote, M. L. and Schiesser, C. H. (2010) First determination of the rate constant for ring-closure of an azahexenoyl radical: 6-aza-7-ethyl-5-hexenoyl. Chemical Communications, 46 (35). pp. 6521-6523. ISSN 1359-7345

Free radical chemistry

Kyne, Sara, Aitken, Hesther M., Horvat, Sonia M., Lin, Ching Yeh, Coote, Michelle L. and Schiesser, Carl H. (2012) Homolytic substitution chemistry: from James Franz to antihypertensives. ChemInform, 43 (30). pp. 927-928. ISSN 0931-7597

Kyne, Sara and Schiesser, Carl H. (2012) Intramolecular homolytic substitutions in synthesis. In: Encyclopedia of Radicals in Chemistry, Biology and Materials. John Wiley and Sons, Ltd., Chichester, UK, pp. 629-654. ISBN 9781119953678

Friedel-Crafts

Eey, Stanley T.-C. and Lear, Martin J. (2014) Total synthesis of (−)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods. Chemistry - A European Journal, 20 (36). pp. 11556-11573. ISSN 0947-6539

Furanocembranoid

Yang, Eugene G., Sekar, Karthik and Lear, Martin J. (2013) A macrolactonisation approach to the cembrane carbocycle of bielschowskysin. Tetrahedron Letters, 54 (33). pp. 4406-4408. ISSN 0040-4039

G-quadruplex

Gas chromatography

Dharmawan, Jorry, Kasapis, Stefan, Sriramula, Praveena, Lear, Martin J. and Curran, Philip (2009) Evaluation of aroma-active compounds in Pontianak Orange Peel Oil (Citrus nobilis Lour. Var.microcarpaHassk.) by gas chromatography−olfactometry, aroma reconstitution, and omission test. Journal of Agricultural and Food Chemistry, 57 (1). pp. 239-244. ISSN 0021-8561

Gemini surfactants

Silva, Sandra G., Pinheiro, Marina, Pereira, Rui, Dias, Ana Rita, Ferraz, Ricardo, Prudêncio, Cristina, Eaton, Peter J., Reis, Salette and do Vale, M. Luísa C. (2022) Serine-based surfactants as effective antimicrobial agents against multiresistant bacteria. BBA - Biomembranes, 1864 (9). p. 183969. ISSN 0005-2736

Globalisation

Lear, Martin J., Salmons, Brian, Gunzburg, Walter H. and Dangerfield, John A. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4 (2). pp. 179-185. ISSN ISSN

Glycobiology

Glycolipids

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Glycosylation

Ohashi, Isao, Lear, Martin J., Yoshimura, Fumihiko and Hirama, Masahiro (2004) Use of polystyrene-supported DBU in the synthesis and α-selective glycosylation study of the unstable Schmidt donor of L-kedarosamine. Organic Letters, 6 (5). pp. 719-722. ISSN 1523-7060

Green chemistry

Grignard addition

Hairpin pyrrole-imidazole polyamides

Hemolytic activity

Hole Transporter

Zhang, Wei, Zhu, Rui, Li, Feng, Wang, Qing and Liu, Bin (2011) High-performance solid-state organic dye sensitized solar cells with P3HT as hole transporter. The Journal of Physical Chemistry C, 115 (14). pp. 7038-7043. ISSN 1932-7447

Homogenous catalysis

Homolytic substitution

Hybrid solar cell

Zhang, Wei, Zhu, Rui, Liu, Bin and Ramakrishna, Seeram (2012) High-performance hybrid solar cells employing metal-free organic dye modified TiO2 as photoelectrode. Applied Energy, 90 (1). pp. 305-308. ISSN 0306-2619

Hydrazone

Kyne, Sara and Schiesser, C. H. (2009) Ab initio studies of carbonyl radical additions to hydrazone systems. Australian Journal of Chemistry, 62 (7). pp. 728-733. ISSN 0004-9425

Hydrogen Bonding

Hyperpolarisation

Imine

Immobilisation chemistry

Immuno-affinity screening

Inositol

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

Insulating surfaces

Interfacial modification

Intermolecular interactions

Gruber, Tobias, Bombicz, Petra, Seichter, Wilhelm and Weber, Edwin (2009) X-ray crystal structures and isostructurality calculation of calix[4]arenes with lower rim propyl and carboxylic acid or mixed carboxylic acid and ester substituents involving solvent complexes with methanol and ethanol. Journal of Structural Chemistry, 50 (3). pp. 522-531. ISSN 0022-4766

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2016) Trimethyl 3,3',3''-(benzene-1,3,5-triyl)tripropynoate. IUCrData, 1 (4). x160629. ISSN 2414-3146

Intermolecular radical addition

Kyne, Sara and Schiesser, C. H. (2009) Ab initio studies of carbonyl radical additions to hydrazone systems. Australian Journal of Chemistry, 62 (7). pp. 728-733. ISSN 0004-9425

Intramolecular

Intramolecular cyclisation

Iron

Isotope labelling

Das, Parthasarathi, Mita, Takashi, Lear, Martin and Hirama, Masahiro (2002) Synthesis of 13C-labelled, bicyclic mimetics of natural enediynes. Chemical Communications (22). pp. 2624-2625. ISSN 1359-7345

Usuki, Toyonobu, Mita, Takashi, Lear, Martin J., Das, Parthasarathi, Yoshimura, Fumihiko, Inoue, Masayuki, Hirama, Masahiro, Akiyama, Kimio and Tero-Kubota, Shozo (2004) Spin trapping of 13C-labeled p-benzynes generated by Masamune–Bergman cyclization of bicyclic nine-membered enediynes. Angewandte Chemie International Edition, 43 (39). pp. 5249-5253. ISSN 1433-7851

JCNotOpen

Pasari, Sandip, Ismail, Shareef M., Wenk, Markus R. and Lear, Martin (2015) Preparation of azide biosynthetic surrogates of myo-Inositol. Tetrahedron Letters, 56 (20). pp. 2597-2601. ISSN 0040-4039

JCOpen

Bombicz, Petra, Gruber, Tobias, Fischer, Conrad, Weber, Edwin and Kálmán, Alajos (2014) Fine tuning of crystal architecture by intermolecular interactions: synthon engineering. CrystEngComm, 16 (18). p. 3646. ISSN 1466-8033

Gil-Ramírez, Guzmán, Leigh, David A. and Stephens, Alexander J. (2015) Catenanes: fifty years of molecular links. Angewandte Chemie International Edition, 54 (21). pp. 6110-6150. ISSN 1433-7851

Gruber, Tobias, Thompson, Amber L., Odell, Barbara, Bombicz, Petra and Schofield, Christopher J. (2014) Conformational studies on substituted ε-caprolactams by X-ray crystallography and NMR spectroscopy. New Journal of Chemistry, 38 (12). pp. 5905-5917. ISSN 1144-0546

Hernández-Alonso, D., Zankowski, S., Adriaenssens, L. and Ballester, P. (2015) Water-soluble aryl-extended calix[4]pyrroles with unperturbed aromatic cavities: synthesis and binding studies. Organic & Biomolecular Chemistry, 13 (4). pp. 1022-1029. ISSN 1477-0520

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2016) Trimethyl 3,3',3''-(benzene-1,3,5-triyl)tripropynoate. IUCrData, 1 (4). x160629. ISSN 2414-3146

Kinetics

Kingianin A

Knoevenagel reaction

L-allo-enduracididine

Lactam

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) The missing link in the homologous series of lactams: the X-ray structure of valerolactam. Crys. Growth Des., 18 (12). pp. 7248-7253. ISSN 1528-7483

Lactam antibiotic

Lactate dehydrogenase

Langmuir monolayers

Laser ablation

Lear, Martin and Hobley, Jonathan (2008) You make it, I break it. COSMOS, 04 (01). pp. 99-129. ISSN 0219-6077

Lead discovery

Lipid II

Fiers, William D., Craighead, Mark and Singh, Ishwar (2017) Teixobactin and its analogues: a new hope in antibiotic discovery. ACS Infectious Diseases, 3 (10). pp. 688-690. ISSN 2373-8227

MIRC

Macrocyclisation

Yang, Eugene G., Sekar, Karthik and Lear, Martin J. (2013) A macrolactonisation approach to the cembrane carbocycle of bielschowskysin. Tetrahedron Letters, 54 (33). pp. 4406-4408. ISSN 0040-4039

Malaria

Malaria detection

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Maleimide reagents

Mechanism

Mechanochemistry

Merocyanine

Merocyanines

Hobley, Jonathan, Lear, Martin and Fukumura, Hiroshi (2003) Photo-switching spiropyrans and related compounds. In: Photochemistry of organic molecules in isotropic and anisotropic media. Marcel Dekker, Inc, pp. 353-404. ISBN 9780824708832, 9780203014202

Metal-free organic dye

Metathesis reactions

Methodology

Mevalonate

Michael addition

Lear, Martin J. and Hayashi, Yujiro (2013) Remote 1,6-stereocontrol by iminium-mediated organocatalytic events. ChemCatChem, 5 (12). pp. 3499-3501. ISSN 1867-3880

Mode-of-action

Lear, Martin (2013) Synthetic ventures into the platensimycins, bielschowskysins, lipstatins, and enediynes. In: Lecture Tour, July 2013, RIKEN, Waseda University, Keio University, Sophia University, Japan.

Molecular Conformation

Fischer, Conrad, Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2011) Bridge-substituted calix[4]arenes: syntheses, conformations and application. Organic & Biomolecular Chemistry, 9 (11). pp. 4347-4352. ISSN 1477-0520

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2008) Crystal structures of a calix[4]arene controlled by two affixed pyrene units. Supramolecular Chemistry, 20 (8). pp. 753-760. ISSN 1061-0278

Gruber, Tobias, Fischer, Conrad, Seichter, Wilhelm, Bombicz, Petra and Weber, Edwin (2011) Upper rim site lipophilic calix[4]arenes as receptors for natural terpenes and functionally related solvent molecules: combined crystal structure and QMB sensor study. CrystEngComm, 13 (5). pp. 1422-1431. ISSN 1466-8033

Gruber, Tobias, Peukert, Max, Schindler, Diana, Seichter, Wilhelm, Weber, Edwin and Bombicz, Petra (2008) Crystalline inclusion compounds of lower rim propyl substituted calix[4]arenes featuring different number and positions of the modifying groups. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 62 (3-4). pp. 311-324. ISSN 0923-0750

Gruner, Margit, Fischer, Conrad, Gruber, Tobias and Weber, Edwin (2010) Influence of laterally attached alkyl groups on the conformational behaviour of a basic calix[4]arene: combined NMR, molecular mechanics and X-ray study. Supramolecular Chemistry, 22 (4). pp. 256-266. ISSN 1061-0278

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma-lactam from a simple caprolactam derivative. New Journal of Chemistry, 41 . pp. 9984-9989. ISSN 1144-0546

Molecular Imaging

Molecular structure

N-terminal fragment

NMR

NMR Spectroscopy

Weck, Christian, Obst, Franziska, Nauha, Elisa, Schofield, Christopher and Gruber, Tobias (2017) Synthesis of a bicyclic oxo-gamma lactam from a simple caprolactam derivative. In: 20th European Symposium on Organic Chemistry, 2-6 July 2017, Cologne, Germany.

NMR spectroscopy

NMR study

Bürger, Marcel, Katzsch, Felix, Brendler, Erica and Gruber, Tobias (2015) Synthesis of macrocyclic receptors with intrinsic fluorescence featuring quinizarin moieties. The Journal of Organic Chemistry, 80 (10). pp. 4882-4892. ISSN 0022-3263

Natural Product

Natural Products

Sharma, Pallavi (2016) Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design . ISSN 1381-6128

Natural enediynes

Koyama, Yasuhito, Lear, Martin J., Yoshimura, Fumihiko, Ohashi, Isao, Mashimo, Tomoko and Hirama, Masahiro (2005) Efficient construction of the kedarcidin chromophore ansamacrolide. Organic Letters, 7 (2). pp. 267-270. ISSN 1523-7060

Lear, Martin (2015) Routes to nine-membered enediynes: not such a walk in the park. In: 64th Gordon Research Conference (GRC) on Natural Products 2015, July 26-31, 2015, Proctor Academy, Andover, NH, USA.

Yoshimura, Fumihiko, Lear, Martin J., Ohashi, Isao, Koyama, Yasuhito and Hirama, Masahiro (2007) Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon. Chemical Communications (29). p. 3057. ISSN 1359-7345

Natural product

Natural products

Lear, Martin (2010) Exploring the glycolipidome via chemical mimicry. In: EMBO Conference Series: Chemical Biology 2010, 22 - 25 Sep 2010, EMBL Heidelberg, Germany.

Lear, Martin (2010) One small step for synthesis; one giant leap for total synthesis. In: 59th Natural Products Gordon Research Conference, July 25-30, 2010, Tilton, NH, USA.

Lear, Martin (2012) Total synthesis and drug pursuits: the good, the bad, and the ugly. In: UK and European Lecture Tour, May - July 2012, St Andrews, Edinburgh, and Glasgow Universities (UK), EPFL (Lausanne, Switzerland), University of Strasbourg (France).

Negishi coupling

Nitrile Oxide

NotOAChecked

Brennecke, Johannes, Ochs, Christopher J., Boudhar, Aïcha, Reux, Bastien, Subramanian, Gomathy Sandhya, Lear, Martin J., Trau, Dieter and Hobley, Jonathan (2014) Design, preparation and assessment of surface-immobilised tetraphenylethenes for biosensing applications. Applied Surface Science, 307 . pp. 475-481. ISSN 0169-4332

Gruber, Tobias, Nestler, Robert, Seichter, Wilhelm and Bombicz, Petra (2014) Crystal structures and isometricity comparison of methylated bisphenol F derivatives. Journal of Molecular Structure, 1056-7 . pp. 319-325. ISSN 0022-2860

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2016) Crystal structures of functional building blocks derived from di(benzo[b]thien-2-yl)methane. Acta Crystallographica C: Structural Chemistry, 72 (9). pp. 679-684. ISSN 2053-2296

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2015) Crystalline inclusion of wheel-and-axle diol hosts featuring benzo[b]thiophene units as a lateral construction element. Crystal Growth & Design, 15 (10). pp. 5047-5061. ISSN 1528-7483

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2016) Structural studies on inclusion compounds and solvent sorption behavior of gradually elongated wheel-and-axle-type diol hosts featuring lateral benzo[b]thiophene units. Journal of Molecular Structure, 1114 . pp. 48-64. ISSN 0022-2860

Kyne, S. H. and Schiesser, C.H. (2014) N,S-Dimethyldithiocarbamyl oxalates as precursors for determining kinetic parameters for oxyacyl radicals. Chemical Communications, 50 (81). pp. 12040-12042. ISSN 1359-7345

Li, Jing, Lear, Martin, Kawamoto, Yuya, Umemiya, Shigenobu, Wong, Alice, Kwon, Eunsang and Hayashi, Yujiro (2015) Oxidative amidation of nitroalkanes with amine nucleophiles using molecular oxygen and iodine. Angewandte Chemie International Edition, 54 (44). pp. 12986-12990. ISSN 1433-7851

Naeem, Ayesha, Ting, Valeska P., Hintermair, Ulrich, Tian, Mi, Telford, Richard, Halim, Saaiba, Nowell, Harriott, Holynska, Malgorzata, Teat, Simon J., Scowen, Ian J. and Nayak, Sanjit (2016) Mixed-linker approach in designing porous zirconium-based metal-organic frameworks with high hydrogen storage capacity. Chemical Communications, 52 (50). pp. 7826-7829. ISSN 1359-7345

Powell, Kimberley J., Han, Li-Chen, Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

Yamada, Kei, Lear, Martin J., Yamaguchi, Takaya, Yamashita, Shuji, Gridnev, Ilya D., Hayashi, Yujiro and Hirama, Masahiro (2014) Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site‐Selective p‐Benzyne Hydrochlorination. Angewandte Chemie International Edition, 53 (50). pp. 13902-13906. ISSN 1433-7851

Odor activity value

Olfractometry

Organic Dye

Organic Sensitizer

Organic Sensitizers

Organic methods

He, Xin, Ma, Pengchen, Tang, Yuhai, Li, Jing, Shen, Shenyu, Lear, Martin, Houk, K.N. and Xu, Silong (2022) Phosphine-catalyzed activation of cyclopropenones: a versatile C3 synthon for (3+2) annulations with unsaturated electrophiles. Chemical Science, 13 (43). ISSN 2041-6539

Lear, Martin (2018) Atypical Oxidative Methods to (A)Typically Activated Esters. In: University College London (UCL)-Tohoku University UK-Japan Organic Symposium, 12 March 2018, Aoba Science Hall, Tohoku University, Japan.

Lear, Martin (2010) One small step for synthesis; one giant leap for total synthesis. In: 59th Natural Products Gordon Research Conference, July 25-30, 2010, Tilton, NH, USA.

Organic synthesis

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2008) Crystal structures of a calix[4]arene controlled by two affixed pyrene units. Supramolecular Chemistry, 20 (8). pp. 753-760. ISSN 1061-0278

Lear, Martin and Hobley, Jonathan (2008) You make it, I break it. COSMOS, 04 (01). pp. 99-129. ISSN 0219-6077

Organic vapor sorption

Organocatalysis

Organocatalyst

Organohalogens

Lightfoot, Ian Peter, Colston, Belinda and Dahm, R (2000) Reductive destruction of chlorinated organics in molten salt. PhD thesis, De Montfort University.

Orlistat

Oxadiazol-5-imine

Oxazoles

P3HT

Palladium catalysis

Powell, Kimberley J., Han, Li-Chen, Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

Peptide synthesis

Peptides

Peptides. PEG

Perinelli, Diego Romano, Campana, Mario, Singh, Ishwar, Vllasaliu, Driton, Doutch, James, Palmieri, Giovanni Filippo and Casettari, Luca (2019) PEGylation affects the self-assembling behaviour of amphiphilic octapeptides. International Journal of Pharmaceutics, 571 (118752).

Photo-switches

Photocatalysis

Photochemistry

Plasmodium

National University of Singapore (2012) Synthesis and use of fluorophore-tagged antimalarials. US20120100555 A1.

Poly(3-hexylthiophene)

Polyketide

Powell, Kimberley J., Sharma, Pallavi, Richens, Joanna L., Daviss, Benjamin M., Moses, John E. and O'Shea, Paul (2012) Interactions of marine-derived γ-pyrone natural products with phospholipid membranes. Physical Chemistry Chemical Physics, 14 (42). pp. 14489-14491. ISSN 1463-9076

Polypropionate

Polythiophene

Protecting groups

Protein tyrosine kinases

QMB measurement

Radical Cation

Radical chemistry

Radical cyclization

Radical reaction

Neves, A. C., Aitken, H. M., Kyne, S. H., Fensterbank, L., Lacote, E., Malacria, M., Ollivier, C. and Schiesser, C. H. (2012) Intramolecular homolytic substitution of seleninates: a computational study. Tetrahedron, 68 (1). pp. 323-328. ISSN 0040-4020

Reaction kinetics

Reduction

SNAP-tag technology

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

Selenium

Self assembly

Self-assembled monolayers

Self-assembly

Sensitized Solar Cells

Serine

Singapore

Lear, Martin J., Salmons, Brian, Gunzburg, Walter H. and Dangerfield, John A. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4 (2). pp. 179-185. ISSN ISSN

Single electron transfer

Singlet Oxygen

Smart optical linkers

National University of Singapore (2013) A microparticle assembly. WO2013176625 A1.

Solid phase

Sharma, Pallavi and Moses, John E. (2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and click linker. Org. Lett., 12 (12). pp. 2860-2863. ISSN 1523-7060

Solid-State

Solvent-free synthesis

Sonogashira

Yang, Eugene G., Sekar, Karthik and Lear, Martin J. (2013) A macrolactonisation approach to the cembrane carbocycle of bielschowskysin. Tetrahedron Letters, 54 (33). pp. 4406-4408. ISSN 0040-4039

Spiropyran

Spiropyran monolayers

Spiropyrans

Stereoisomer synthesis

Stereoselective

Stereoselective glycosylation

Structure-Activity Relationship

Sulfinamides

Sulfinates

Supramolecular chemistry

Gruber, Tobias (2019) From Supramolecular Methyllysine Receptors to Bridged Caprolactams. In: NZIC Seminar, 16th January 2019, University of Auckland.

Sustainable chemistry

Teixobactins

Fiers, William D., Craighead, Mark and Singh, Ishwar (2017) Teixobactin and its analogues: a new hope in antibiotic discovery. ACS Infectious Diseases, 3 (10). pp. 688-690. ISSN 2373-8227

Telomerase

Tetraols

Tetrapeptide

Total synthesis

Lear, Martin (2010) One small step for synthesis; one giant leap for total synthesis. In: 59th Natural Products Gordon Research Conference, July 25-30, 2010, Tilton, NH, USA.

Lear, Martin (2017) Total Synthesis of Complex & Unstable Nine-membered Enediynes. In: Lecture Tour, January 2017, Osaka Prefecture University, Osaka Institute of Technology, Sophia University, 8-22 January 2016, Japan.

Lear, Martin (2017) The total synthesis of the kedarcidin chromophore: A 20-year Odyssey. In: Gregynog Synthesis Workshop 2017, 13-15 September 2017, Gregynog Hall, Wales, UK.

Lear, Martin, Hirai, Keiichiro, Ogawa, Kouki, Yamashita, Shinji and Hirama, Masahiro (2019) A Convergent Total Synthesis of the Kedarcidin Chromophore: 20-Years in the Making. Journal of Antibiotics, 72 (6). pp. 350-363. ISSN 0021-8820

Lear, Martin and Yao, Shao Q. (2010) New directions for old drugs. Project Report. National University of Singapore, Singapore.

Sharma, Pallavi (2016) Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design . ISSN 1381-6128

Total synthesis studies

Gramani, Subramanian G., Sriramula, Ravi K., Sekar, Karthik, Yang, Eugene G., Battu, Praveena, Kopecky, Aïcha and Lear, Martin (2021) Cis Selective RCM Study to the 14-Membered Cyclic Subunit of Bielschowskysin. Journal of Organic Chemistry, 86 (9). pp. 6160-6168. ISSN 0022-3263

Transannular ring-opening

Triazole

Trifluormethyl

Triphenylamine

Tyrophostins

Tyrphostins

Valerolactam

Virtual screening

Wittig synthesis

Pezzi, Marco, Zamberlan, Francesco, Chicca, Milvia and Leis, Marilena (2018) Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid against Aedes albopictus (Diptera: Culicidae). Saudi Journal of Biological Sciences . ISSN 1319-562X

X-ray diffraction

Augustin, Andre U., Katzsch, Felix, Prior, Stephen H. and Gruber, Tobias (2017) Supramolecular layers and versatile packing modes: the solid state behavior of ortho, ortho-linked bisphenols. Journal of Molecular Structure, 1135 . pp. 153-165. ISSN 0022-2860

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2008) Crystal structures of a calix[4]arene controlled by two affixed pyrene units. Supramolecular Chemistry, 20 (8). pp. 753-760. ISSN 1061-0278

Gruber, Tobias, Schofield, Christopher J. and Thompson, Amber L. (2012) Methyl 6-amino-6-oxohexanoate. Acta Crystallographica Section E: Structure Reports Online, 68 (3). o593-o594. ISSN 0365-110X

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2010) 1-(Hydroxymethyl)pyrene. Acta Crystallographica Section E: Structure Reports Online, 66 (2). o443. ISSN 0365-110X

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2006) 1-(Methoxymethyl)pyrene. Acta Crystallographica Section E: Structure Reports Online, 62 (6). o2569-o2570. ISSN 0365-110X

Nestler, Robert, Schwarzer, Anke and Gruber, Tobias (2018) Different supramolecular interactions mediated by bromine atoms in the crystal structures of three anisole derivatives. Acta Crystallographica Section C Structural Chemistry, C74 (3). pp. 283-288. ISSN 2053-2296

X-ray structure

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2016) Trimethyl 3,3',3''-(benzene-1,3,5-triyl)tripropynoate. IUCrData, 1 (4). x160629. ISSN 2414-3146

X-ray studies

X-ray study

Gruber, Tobias, Weber, Edwin, Seichter, Wilhelm, Bombicz, Petra and Csöregh, Ingeborg (2007) Versatile inclusion behaviour of a dinitrocalix[4]arene having two ester pendants: preparation and X-ray crystal structures of complexes. Supramolecular Chemistry, 18 (6). pp. 537-547. ISSN 1061-0278

Xenon

Zirconium

[3+2] cycloaddition

addition reactions

alkyl chain

alkyne silane

Sharma, Pallavi and Moses, John E. (2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and click linker. Org. Lett., 12 (12). pp. 2860-2863. ISSN 1523-7060

amidation

Li, Jing, Lear, Martin and Hayashi, Yujiro (2018) Autoinductive Conversion of alpha,alpha-Diiodonitroalkanes to Amides and Esters Catalysed by Iodine Byproducts under O2. Chemical Communications, 49 . pp. 6360-6363. ISSN 1359-7345

amide

Sharma, Pallavi, Moorhouse, Adam D. and Moses, John E. (2011) Microwave enhanced tandem azidation-amidation of anilines. Synlett, 2011 (16). pp. 2384-2386. ISSN 0936-5214

amino acid

anisole

anti-tumour agents

antibiotics

Fiers, William D., Craighead, Mark and Singh, Ishwar (2017) Teixobactin and its analogues: a new hope in antibiotic discovery. ACS Infectious Diseases, 3 (10). pp. 688-690. ISSN 2373-8227

antibiotics•antimicrobial resistance•drug development•lipid II•MRSA•Mycobacterium tuberculosis •peptides•Teixobactin•VRE

Iyer, Abhishek, Madder, Annemieke and Singh, Ishwar (2019) Teixobactins: a new class of 21st century antibiotics to combat multi-drug resistant bacterial pathogens. Future Microbiology, 14 . pp. 457-460. ISSN 1746-0913

antimalarial

antimicrobial activity

antiparasitic agents

Yang, Peng-Yu, Wang, Min, Liu, Kai, Ngai, Mun Hong, Sheriff, Omar, Lear, Martin J., Sze, Siu Kwan, He, Cynthia Y. and Yao, Shao Q. (2012) Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti trypanosoma brucei agent. Chemistry - A European Journal, 18 (27). pp. 8403-8413. ISSN 0947-6539

arsenic

artificial receptor

Gruber, Tobias (2017) Synthetic receptors for the recognition and discrimination of epigenetically modified lysines. In: 25th Annual GP2A Medicinal Chemistry Conference, 31st August - 1st September 2017, Liverpool.

asymmetric induction

Lear, Martin J. and Hayashi, Yujiro (2013) Remote 1,6-stereocontrol by iminium-mediated organocatalytic events. ChemCatChem, 5 (12). pp. 3499-3501. ISSN 1867-3880

azide

Sharma, Pallavi, Moorhouse, Adam D. and Moses, John E. (2011) Microwave enhanced tandem azidation-amidation of anilines. Synlett, 2011 (16). pp. 2384-2386. ISSN 0936-5214

benzenoids

benzothiophen

benzyne

bioassay

bioimaging

bioisotere

biomimetic synthesis

Sharma, Pallavi, Griffiths, Nicholas and Moses, John E. (2008) Biomimetic synthesis and structural revision of tridachiahydropyrone. Organic Letters, 10 (18). pp. 4025-4027. ISSN 1523-7060

Sharma, Pallavi, Lygo, Barry, Williams, Lewis and Moses, John E. (2009) Biomimetic synthesis and structural reassignment of the tridachiahydropyrones. Journal of the American Chemical Society, 131 (16). pp. 5966-5972. ISSN 0002-7863

bismuth

bisphenol

bisphenols

bmjdoi

Sharma, Pallavi (2016) Biomimetic approaches towards the synthesis of complex dimeric natural products. Current Pharmaceutical Design . ISSN 1381-6128

bmjgoldcheck

bromine bromine interactions

bulk insulator

calcite

calixarene

Gruber, Tobias (2017) Artificial receptors for the discrimination of epigenetically modified lysines. In: Dial-a-Molecule Annual Meeting 2017, 21 June 2017, Liverpool.

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Chemiedozententagung 2018, 5 -7 March 2018, Jena, Germany.

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Macrocycles in Medicine, 17th-20th December 2018, Norwich.

caprolactam

catalysis

Li, Jing, Kwon, Eunsang, Lear, Martin and Hayashi, Yujiro (2021) Halogen Bonding of N-Halosuccinimides with Amines and Effects of Brønsted Acids in Quinuclidine-Catalyzed Halocyclizations. Helvetica Chimica Acta, 104 (9). e2100080. ISSN 0018-019X

catenanes; interlocked molecules; links; supramolecular chemistry; template synthesis

Gil-Ramírez, Guzmán, Leigh, David A. and Stephens, Alexander J. (2015) Catenanes: fifty years of molecular links. Angewandte Chemie International Edition, 54 (21). pp. 6110-6150. ISSN 1433-7851

chemical biology

Gruber, Tobias (2017) Artificial receptors for the discrimination of epigenetically modified lysines. In: Dial-a-Molecule Annual Meeting 2017, 21 June 2017, Liverpool.

chemical proteomics

chemisorption

Song, Hongyan, Gorelik, Sergey, Hobley, Jonathan, Li, Jiexun, Boudhar, AÏcha and Lear, Martin J. (2013) Pyrene emission from monolayers 'clicked' onto quartz. Journal of Molecular and Engineering Materials, 01 (01). pp. 1250007-1. ISSN 2251-2373

chlorinated organics

Lightfoot, Ian Peter, Colston, Belinda and Dahm, R (2000) Reductive destruction of chlorinated organics in molten salt. PhD thesis, De Montfort University.

click chemistry

computational modeling

conformational analysis

conformational studies

conglomerate

conjugate reduction

conjugation

Lear, Martin J. and Hayashi, Yujiro (2013) Remote 1,6-stereocontrol by iminium-mediated organocatalytic events. ChemCatChem, 5 (12). pp. 3499-3501. ISSN 1867-3880

covalent assembly

cyanamide; synthesis; aminocyanation; cycloaddition; electrophilic cyanation; radical reaction; coordination chemistry

Ranga Prabhath, M. R., Williams, Luke, Bhat, Shreesha V. and Sharma, Pallavi (2017) Recent advances in cyanamide chemistry: synthesis and applications. Molecules, 22 (4). p. 615. ISSN 1420-3049

cyanoacetic acid

cyclization

cyclophane

cyclopropane

dimerization

diradicals

drug discovery

drug synthesis

electrocyclisation

Sharma, Pallavi, Griffiths, Nicholas and Moses, John E. (2008) Biomimetic synthesis and structural revision of tridachiahydropyrone. Organic Letters, 10 (18). pp. 4025-4027. ISSN 1523-7060

electronic decoupling

enediynes

epigenetics

esterification

excimer

falcipain

falcitidin

fluorescence

fluorescent dye

fluorescent probes

fluorescophane

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Chemiedozententagung 2018, 5 -7 March 2018, Jena, Germany.

gamma pyrone

Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN 0936-5214

geomorphology

glycolysis

halogen bonding

halogen interactions

hazardous waste

Lightfoot, Ian Peter, Colston, Belinda and Dahm, R (2000) Reductive destruction of chlorinated organics in molten salt. PhD thesis, De Montfort University.

heteroaromatic compound

heterocycle

heterocycles

Baricordi, Nikla, Benetti, Simonetta, Bertolasi, Valerio, De Risi, Carmela, Pollini, Gian P., Zamberlan, Francesco and Zanirato, Vinicio (2012) 1,4-Dithiane-2,5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes. Tetrahedron, 68 (1). pp. 208-213. ISSN 0040-4020

heterogeneous catalysis

homolytic substitution

host-guest

hydrogen storage

hyperpolarisation

iminium

Lear, Martin J. and Hayashi, Yujiro (2013) Remote 1,6-stereocontrol by iminium-mediated organocatalytic events. ChemCatChem, 5 (12). pp. 3499-3501. ISSN 1867-3880

inclusion compound

indole alkaloid

Chavan, Subhash P., Sharma, Pallavi, Sivappa, R. and Kalkote, Uttam R. (2006) A ring closing metathesis approach to the indole alkaloid mitralactonine. Tetrahedron Letters, 47 (52). pp. 9301-9303. ISSN 0040-4039

Chavan, Subhash P., Sharma, Pallavi, Sivappa, Rasapalli and Kalkote, Uttam R. (2007) A practical and facile approach towards indole alkaloids: (-)-mitralactonine. Synlett, 2007 (01). pp. 79-82. ISSN 0936-5214

iodination

iodine

irradiation

isometricity comparison

isostructurality

kinetics

lactam

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) Crystal behavior of lactams and the missing link δ-valerolactam. In: BCA Spring Meeting 2018, 26th-29th March 2018, Coventry.

lactams

Gruber, Tobias (2019) From Supramolecular Methyllysine Receptors to Bridged Caprolactams. In: NZIC Seminar, 16th January 2019, University of Auckland.

larvicidal

layered material

macrocycle

Gruber, Tobias (2019) From Supramolecular Methyllysine Receptors to Bridged Caprolactams. In: NZIC Seminar, 16th January 2019, University of Auckland.

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Chemiedozententagung 2018, 5 -7 March 2018, Jena, Germany.

macrocyclic compound

Gruber, Tobias (2016) From artificial antibodies to bridged caprolactams. In: Invited Lecture hosted by the School of Pharmacy, University of East Anglia., 12 January 2016, Norwich.

malaria

materials chemistry

metal-organic frameworks

methodology

methyllysine

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Macrocycles in Medicine, 17th-20th December 2018, Norwich.

microparticles

mitralactonine

mixed-linker

mixtures

molecular electronics

molecular overlay calculation

molecular recognition

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Macrocycles in Medicine, 17th-20th December 2018, Norwich.

mollusc

Sharma, Pallavi, Griffiths, Nicholas and Moses, John E. (2008) Biomimetic synthesis and structural revision of tridachiahydropyrone. Organic Letters, 10 (18). pp. 4025-4027. ISSN 1523-7060

Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN 0936-5214

monochlorination

morphotropism

mosquito

myxobacteria

oapaid

Powell, Kimberley J., Han, Li-Chen, Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN 1523-7060

on-surface synthesis

on-surface synthesis on insulators

organic chemistry

Gruber, Tobias (2019) From Supramolecular Methyllysine Receptors to Bridged Caprolactams. In: NZIC Seminar, 16th January 2019, University of Auckland.

Kobayashi, Shoji, Yamaguchi, Ryo, Yamamoto, Fumiya, Komori, Jun, Sakamoto, Hotaka, Kasashima, Takahiro, Adriaenssens, Louis and Lear, Martin (2023) One-Pot Conversion of Benzyl Alcohols to N-Protected Anilines and Alkyl Alcohols to Carbamoyl Azides. European Journal of Organic Chemistry . e202300786. ISSN 1434-193X

Lear, Martin (2017) The total synthesis of the kedarcidin chromophore: A 20-year Odyssey. In: Gregynog Synthesis Workshop 2017, 13-15 September 2017, Gregynog Hall, Wales, UK.

organic synthesis

organocatalysis

Lear, Martin J. and Hayashi, Yujiro (2013) Remote 1,6-stereocontrol by iminium-mediated organocatalytic events. ChemCatChem, 5 (12). pp. 3499-3501. ISSN 1867-3880

orlistat

p-Benzynes

peptide formation

phochemical

Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN 0936-5214

photochemical

photosensitizer

polypropionate

Sharma, Pallavi, Griffiths, Nicholas and Moses, John E. (2008) Biomimetic synthesis and structural revision of tridachiahydropyrone. Organic Letters, 10 (18). pp. 4025-4027. ISSN 1523-7060

Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN 0936-5214

proteomics

pyrene

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2008) Crystal structures of a calix[4]arene controlled by two affixed pyrene units. Supramolecular Chemistry, 20 (8). pp. 753-760. ISSN 1061-0278

Gruber, Tobias, Seichter, Wilhelm and Weber, Edwin (2006) 1-(Methoxymethyl)pyrene. Acta Crystallographica Section E: Structure Reports Online, 62 (6). o2569-o2570. ISSN 0365-110X

radical

reactivity

reagentless assay

reductive destruction

Lightfoot, Ian Peter, Colston, Belinda and Dahm, R (2000) Reductive destruction of chlorinated organics in molten salt. PhD thesis, De Montfort University.

rhodanine-3-acetic acid

ring closing metathesis

sedimentary organic material

self assembly

self-defence

Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN 0936-5214

sensor active material

singlet oxygen

solid state

solvent inclusion

sulfur

sulphur

supramolecular chemistry

Gruber, Tobias (2017) Artificial receptors for the discrimination of epigenetically modified lysines. In: Dial-a-Molecule Annual Meeting 2017, 21 June 2017, Liverpool.

Gruber, Tobias (2018) Supramolecular receptors for the recognition and discrimination of epigenetically modified lysines. In: Macrocycles in Medicine, 17th-20th December 2018, Norwich.

synthon

teixobactin

tetrapeptide

tetraphenylethene

thio-acid

Sharma, Pallavi, Moorhouse, Adam D. and Moses, John E. (2011) Microwave enhanced tandem azidation-amidation of anilines. Synlett, 2011 (16). pp. 2384-2386. ISSN 0936-5214

total synthesis

tridachiahydropyrone

trimesic acid homologue

Katzsch, Felix, Gruber, Tobias and Weber, Edwin (2016) Trimethyl 3,3',3''-(benzene-1,3,5-triyl)tripropynoate. IUCrData, 1 (4). x160629. ISSN 2414-3146

trypanosomiasis

umpolung

valerolactam

Weck, Christian, Nauha, Elisa and Gruber, Tobias (2018) Crystal behavior of lactams and the missing link δ-valerolactam. In: BCA Spring Meeting 2018, 26th-29th March 2018, Coventry.

visible light photosensitizer

water

wheel-and-axle host

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