AFM

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Ab-initio computation

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Aggregation

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Alternate conformation

Elmabrouk, Zainab H., Vincent, Florence, Zhang, Meng, Smith, Nicola L., Turkenberg, Johan P., Charnock, Simon J., Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

Animal Biotechnology

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Biologics

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Biomaterials

Saccardo, Angela, Soloviev, Mikhail and Ferrari, Enrico (2020) A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins. Biomaterials Science, 8 (9). pp. 2673-2681. ISSN 2047-4830

BopE

Upadhyay, Abhishek, Williams, Christopher, Gill, Andrew C., Philippe, Didier L., Davis, Kenneth, Taylor, Lowrie A., Stevens, Mark P., Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

Breast cancer

Woolf, David, Williams, Norman, Bakshi, Raheleh, Madani, Seyed Yazdan, Eaton, David, Fawcitt, Sara, Pigott, Katharine, Short, Susan and Keshtgar, Mohammed (2014) Biological dosimetry for breast cancer radiotherapy: a comparison of external beam and intraoperative radiotherapy. SpringerPlus, 3 . pp. 329-335. ISSN 0

Burkholderia pseudomallei

Upadhyay, Abhishek, Williams, Christopher, Gill, Andrew C., Philippe, Didier L., Davis, Kenneth, Taylor, Lowrie A., Stevens, Mark P., Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

CD154

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

CD40 antigen

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

CD40 ligand

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

COVID-19

Igwe, Paul Agu (2020) COVID-19: Policy response, fallout and challenges in Nigeria – Punch Newspapers. Punch Newspaper, 18-06 (2020).

COVID-19 and authoritarianism

Igwe, Paul Agu (2020) COVID-19: Policy response, fallout and challenges in Nigeria – Punch Newspapers. Punch Newspaper, 18-06 (2020).

Calcium binding

Periz, Javier, Gill, Andrew C., Knott, Vroni, Handford, Penny A. and Tomley, Fiona M. (2005) Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. Molecular and Biochemical Parasitology, 143 (2). pp. 192-199. ISSN 0166-6851

Cardiac toxicity

Woolf, David, Williams, Norman, Bakshi, Raheleh, Madani, Seyed Yazdan, Eaton, David, Fawcitt, Sara, Pigott, Katharine, Short, Susan and Keshtgar, Mohammed (2014) Biological dosimetry for breast cancer radiotherapy: a comparison of external beam and intraoperative radiotherapy. SpringerPlus, 3 . pp. 329-335. ISSN 0

Carotenoids

Karki, Khadga Jung, Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Cellular uptake

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Chicken

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Complexed structures

Elmabrouk, Zainab H., Vincent, Florence, Zhang, Meng, Smith, Nicola L., Turkenberg, Johan P., Charnock, Simon J., Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

Coronavirus

Chen, Hongying, Gill, Andrew C., Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

Igwe, Paul Agu (2020) COVID-19: Policy response, fallout and challenges in Nigeria – Punch Newspapers. Punch Newspaper, 18-06 (2020).

Cytokines

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

DNA aptamer

Bibby, David F., Gill, Andrew, Kirby, Louise, Farquhar, Christine F., Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

DNase

Korczynska, Justyna E., Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

Drug aggregation

Karki, Khadga Jung, Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Eimeria

Periz, Javier, Gill, Andrew C., Hunt, Lawrence, Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

Periz, Javier, Gill, Andrew C., Knott, Vroni, Handford, Penny A. and Tomley, Fiona M. (2005) Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. Molecular and Biochemical Parasitology, 143 (2). pp. 192-199. ISSN 0166-6851

Evolution

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Exolytic

Elmabrouk, Zainab H., Vincent, Florence, Zhang, Meng, Smith, Nicola L., Turkenberg, Johan P., Charnock, Simon J., Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

Exosomes

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Flow cytometry

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Fusion protein

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

GASC

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

GPI anchor

Hicks, Matthew R., Gill, Andrew C., Bath, Imanpreet K., Rullay, Atvinder K., Sylvester, Ian D., Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X

Glioma

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

H2AX

Woolf, David, Williams, Norman, Bakshi, Raheleh, Madani, Seyed Yazdan, Eaton, David, Fawcitt, Sara, Pigott, Katharine, Short, Susan and Keshtgar, Mohammed (2014) Biological dosimetry for breast cancer radiotherapy: a comparison of external beam and intraoperative radiotherapy. SpringerPlus, 3 . pp. 329-335. ISSN 0

Hsp90; MAP kinase; Slt2(Mpk1); Transcription activation; Yeast.

Millson, Stefan H., Truman, Andrew W. and Piper, Peter W. (2022) Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast. Cell Stress and Chaperones, 27 (3). pp. 295-304. ISSN 1466-1268

Hyaluronate lyase

Elmabrouk, Zainab H., Vincent, Florence, Zhang, Meng, Smith, Nicola L., Turkenberg, Johan P., Charnock, Simon J., Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

IBV

Chen, Hongying, Gill, Andrew C., Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

Intraoperative radiotherapy

Woolf, David, Williams, Norman, Bakshi, Raheleh, Madani, Seyed Yazdan, Eaton, David, Fawcitt, Sara, Pigott, Katharine, Short, Susan and Keshtgar, Mohammed (2014) Biological dosimetry for breast cancer radiotherapy: a comparison of external beam and intraoperative radiotherapy. SpringerPlus, 3 . pp. 329-335. ISSN 0

JCCluster

Campbell, Lauren, Gill, Andrew, McGovern, Gillian, Jalland, Clara M.O, Hopkins, John, Tranulis, Michael A., Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Marcus theory

Verma, Rajni, Schwaneberg, Ulrich, Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

Mf2

Korczynska, Justyna E., Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

Molecular dynamics

Kirby, Louise, Agarwal, Sonya, Graham, James F., Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Molecular dynamics simulations

Karki, Khadga Jung, Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

NMR structure

Rhie, Alexandre, Kirby, Louise, Sayer, Natalie, Wellesley, Rosanna, Disterer, Petra, Sylvester, Ian, Gill, Andrew C., Hope, James, James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Tahiri-Alaoui, Abdessamad, Gill, Andrew C., Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

Natural Compounds

Karki, Khadga Jung, Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Neurodegeneration

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

NotOAChecked

Karki, Khadga Jung, Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Verma, Rajni, Schwaneberg, Ulrich, Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

Oxidative stress

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Parasite

Periz, Javier, Gill, Andrew C., Hunt, Lawrence, Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

Periz, Javier, Gill, Andrew C., Knott, Vroni, Handford, Penny A. and Tomley, Fiona M. (2005) Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. Molecular and Biochemical Parasitology, 143 (2). pp. 192-199. ISSN 0166-6851

PrPSc

Bibby, David F., Gill, Andrew, Kirby, Louise, Farquhar, Christine F., Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Prion

Kirby, Louise, Agarwal, Sonya, Graham, James F., Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Protein Structure

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew, Agarwal, Sonya, Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Kirby, Louise, Agarwal, Sonya, Graham, James F., Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Protein complex

Periz, Javier, Gill, Andrew C., Hunt, Lawrence, Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

Protein engineering

Saccardo, Angela, Soloviev, Mikhail and Ferrari, Enrico (2020) A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins. Biomaterials Science, 8 (9). pp. 2673-2681. ISSN 2047-4830

Protein misfolding

Kirby, Louise, Agarwal, Sonya, Graham, James F., Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Kirby, Louise, Goldmann, Wilfred, Houston, Fiona, Gill, Andrew C. and Manson, Jean C. (2006) A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres. Journal of General Virology, 87 (12). pp. 3747-3751. ISSN 0022-1317

RNA aptamer

Rhie, Alexandre, Kirby, Louise, Sayer, Natalie, Wellesley, Rosanna, Disterer, Petra, Sylvester, Ian, Gill, Andrew C., Hope, James, James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Raman Spectroscopy

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Recombinant protein

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

SELEX

Bibby, David F., Gill, Andrew, Kirby, Louise, Farquhar, Christine F., Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Secondary

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew, Agarwal, Sonya, Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Kirby, Louise, Agarwal, Sonya, Graham, James F., Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Self-diffusion coefficient

Karki, Khadga Jung, Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Size Exclusion

Periz, Javier, Gill, Andrew C., Hunt, Lawrence, Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

SopD

Wood, Michael W., Williams, Christopher, Upadhyay, Abhishek, Gill, Andrew C., Philippe, Didier L., Galyov, Edouard E., van den Elsen, Jean M.H. and Bagby, Stefan (2004) Structural analysis of Salmonella enterica effector protein SopD. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (2). pp. 219-226. ISSN 1570-9639

Streptomyces coelicolor A3(2)

Elmabrouk, Zainab H., Vincent, Florence, Zhang, Meng, Smith, Nicola L., Turkenberg, Johan P., Charnock, Simon J., Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

TNFR

Tregaskes, Clive A., Glansbeek, Harrie L., Gill, Andrew C., Hunt, Lawrence G., Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Trans-epithelial electrical resistance (TEER)

Karwad, Mustafa A., Macpherson, Tara, Wang, Bo, Theophilidou, Elena, Sarmad, Sarir, Barrett, David A., Larvin, Michael, Wright, Karen L., Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

Transgenic animals

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Type III secretion system

Upadhyay, Abhishek, Williams, Christopher, Gill, Andrew C., Philippe, Didier L., Davis, Kenneth, Taylor, Lowrie A., Stevens, Mark P., Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

acetylation

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

adhesion

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

amyloid

Baskakov, Ilia, Disterer, Petra, Breydo, Leonid, Shaw, Michael, Gill, Andrew, James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

Whyte, Sheena M., Sylvester, Ian D., Martin, Stephen R., Gill, Andrew C., Wopfner, Franziska, Schatzl, Hermann M., Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

amyloid fibrils

Blanch, Ewan W., Gill, Andrew, Rhie, Alexandre G.O., Hope, James, Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

angiotensin-converting enzyme inhibitors

Tereza Fernandez, M., Manuela Silva, M., Mira, Lurdes, Helena Florêncio, M., Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

antioxidants

Tereza Fernandez, M., Manuela Silva, M., Mira, Lurdes, Helena Florêncio, M., Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

apicomplexa

Brown, Philip J., Gill, Andrew, Nugent, Philip G., McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

apple domain

Brown, Philip J., Gill, Andrew, Nugent, Philip G., McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

arachidonyl ethanolamide or Anandamide (AEA)

Karwad, Mustafa A., Macpherson, Tara, Wang, Bo, Theophilidou, Elena, Sarmad, Sarir, Barrett, David A., Larvin, Michael, Wright, Karen L., Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

arginine modification

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

artificial membrane

Hollinshead, Clare M, Hanna, M, Barlow, D J, De Biasi, V, Bucknall, D G, Camilleri, P, Hutt, A J, Lawrence, M J, Lu, J and Su, T J (1999) Determination of the structure of a novel type of artificial membrane by neutron reflectivity. Journal of Pharmacy and Phamacology, 51 (S). p. 90. ISSN 0022-3573

beta-turn

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

biopolymers

Gill, Andrew, Jennings, Keith R., Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

bovine fetuin

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

captopril

Tereza Fernandez, M., Manuela Silva, M., Mira, Lurdes, Helena Florêncio, M., Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

cell free conversion

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

circadian rhythm

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

circular dichroism

Upadhyay, Abhishek, Williams, Christopher, Gill, Andrew C., Philippe, Didier L., Davis, Kenneth, Taylor, Lowrie A., Stevens, Mark P., Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

citrulline

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

co-solute effect

Verma, Rajni, Schwaneberg, Ulrich, Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

coiled coil

Saccardo, Angela, Soloviev, Mikhail and Ferrari, Enrico (2020) A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins. Biomaterials Science, 8 (9). pp. 2673-2681. ISSN 2047-4830

collision cross section

Gill, Andrew, Jennings, Keith R., Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

conformational change

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

conformations

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

creutzfeldt jakob disease

Bocharova, Olga V., Breydo, Leonid, Salnikov, Vadim V., Gill, Andrew and Baskakov, Ilia V. (2005) Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPScfrom sporadic Creutzfeldt-Jakob Disease. Protein Science, 14 (5). pp. 1222-1232. ISSN 1469-896X

Haire, L.F., Whyte, S.M., Vasisht, N., Gill, Andrew C., Verma, C., Dodson, E.J., Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

Rhie, Alexandre, Kirby, Louise, Sayer, Natalie, Wellesley, Rosanna, Disterer, Petra, Sylvester, Ian, Gill, Andrew C., Hope, James, James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

deimination

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

differential scanning calorimetry

Upadhyay, Abhishek, Williams, Christopher, Gill, Andrew C., Philippe, Didier L., Davis, Kenneth, Taylor, Lowrie A., Stevens, Mark P., Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

differentiation

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

dimyristoylphosphatidylcholine

Hollinshead, Clare M, Hanna, M, Barlow, D J, De Biasi, V, Bucknall, D G, Camilleri, P, Hutt, A J, Lawrence, M J, Lu, J and Su, T J (1999) Determination of the structure of a novel type of artificial membrane by neutron reflectivity. Journal of Pharmacy and Phamacology, 51 (S). p. 90. ISSN 0022-3573

dynamics

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

electron pathways

Verma, Rajni, Schwaneberg, Ulrich, Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

electrospray mass spectrometry

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

Tereza Fernandez, M., Manuela Silva, M., Mira, Lurdes, Helena Florêncio, M., Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

fibrillisation

Campbell, Lauren, Gill, Andrew, McGovern, Gillian, Jalland, Clara M.O, Hopkins, John, Tranulis, Michael A., Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Graham, James F., Kurian, Dominic, Agarwal, Sonya, Toovey, Lorna, Hunt, Lawrence, Kirby, Louise, Pinheiro, Teresa J. T., Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding In vitro and links PrP function and dysfunction. PLoS ONE, 6 (11). e26813. ISSN 1932-6203

gas phase

Gill, Andrew, Jennings, Keith R., Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

glycation

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

glycosylation

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

gm1

Sanghera, Narinder, Correia, Bruno E.F.S., Correia, Joana R.S., Ludwig, Christian, Agarwal, Sonya, Nakamura, Hironori K., Kuwata, Kazuo, Samain, Eric, Gill, Andrew, Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

gold nanoparticles

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

guanine nucleotide exchange factor

Upadhyay, Abhishek, Williams, Christopher, Gill, Andrew C., Philippe, Didier L., Davis, Kenneth, Taylor, Lowrie A., Stevens, Mark P., Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

hydroxylysine

Ritchie, Mark A., Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

hydroxyproline

Gill, Andrew, Ritchie, M. A., Hunt, L. G., Steane, S. E., Davies, K. G., Bocking, S. P., Rhie, A. G. O., Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

ion mobility

Gill, Andrew, Jennings, Keith R., Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

lipid raft

Sanghera, Narinder, Correia, Bruno E.F.S., Correia, Joana R.S., Ludwig, Christian, Agarwal, Sonya, Nakamura, Hironori K., Kuwata, Kazuo, Samain, Eric, Gill, Andrew, Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

lysozyme; peptidoglycan cleavage; avian gut GH22; crystal structure

Taylor, Edward, Skjøt, Michael, Skov, Lars K., Klausen, Mikkel, De Maria, Leonardo, Gippert, Garry P., Turkenburg, Johan P., Davies, Gideon J. and Wilson, Keith S. (2019) The C-Type Lysozyme from the upper Gastrointestinal Tract of Opisthocomus hoatzin, the Stinkbird. International Journal of Molecular Sciences, 20 (22). ISSN 1422-0067

mass spectrometry

Brown, Philip J., Gill, Andrew, Nugent, Philip G., McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

Chen, Hongying, Gill, Andrew C., Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

Gill, Andrew, Jennings, Keith R., Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

mediated electron transfer

Verma, Rajni, Schwaneberg, Ulrich, Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

melatonin

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

membrane anchor

Hicks, Matthew R., Gill, Andrew C., Bath, Imanpreet K., Rullay, Atvinder K., Sylvester, Ian D., Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X

metal chelation

Tereza Fernandez, M., Manuela Silva, M., Mira, Lurdes, Helena Florêncio, M., Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

methylation

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

microneme

Brown, Philip J., Gill, Andrew, Nugent, Philip G., McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

modular assembly

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

mutation

Tahiri-Alaoui, Abdessamad, Gill, Andrew C., Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

myelin maintenance

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

n-linked glycans

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

neutron reflection

Hollinshead, Clare M, Hanna, M, Barlow, D J, De Biasi, V, Bucknall, D G, Camilleri, P, Hutt, A J, Lawrence, M J, Lu, J and Su, T J (1999) Determination of the structure of a novel type of artificial membrane by neutron reflectivity. Journal of Pharmacy and Phamacology, 51 (S). p. 90. ISSN 0022-3573

nitrative stress

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

nitro-tyrosine

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

nucleocapsid protein

Chen, Hongying, Gill, Andrew C., Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

o-linked glycosylation

Ritchie, Mark A., Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

oleoylethanolamine (OEA)

Karwad, Mustafa A., Macpherson, Tara, Wang, Bo, Theophilidou, Elena, Sarmad, Sarir, Barrett, David A., Larvin, Michael, Wright, Karen L., Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

paired helical filaments

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

palmitoylethanolamine (PEA)

Karwad, Mustafa A., Macpherson, Tara, Wang, Bo, Theophilidou, Elena, Sarmad, Sarir, Barrett, David A., Larvin, Michael, Wright, Karen L., Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

pentosan polysulphate

Brimacombe, Debbie B., Bennett, Alan D., Wusteman, Fred S., Gill, Andrew C., Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

peptide fragmentation

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

peptide quantification

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

peroxisome proliferator-activated receptor (PPAR)

Karwad, Mustafa A., Macpherson, Tara, Wang, Bo, Theophilidou, Elena, Sarmad, Sarir, Barrett, David A., Larvin, Michael, Wright, Karen L., Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

phage

Korczynska, Justyna E., Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

plasminogen

Brown, Philip J., Gill, Andrew, Nugent, Philip G., McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

ploylysine

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

polymorphism

Baskakov, Ilia, Disterer, Petra, Breydo, Leonid, Shaw, Michael, Gill, Andrew, James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

Tahiri-Alaoui, Abdessamad, Gill, Andrew C., Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

polyproline

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

polyproline helix

Blanch, Ewan W., Gill, Andrew, Rhie, Alexandre G.O., Hope, James, Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

Gill, Andrew, Ritchie, M. A., Hunt, L. G., Steane, S. E., Davies, K. G., Bocking, S. P., Rhie, A. G. O., Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

post translational modification

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Gill, Andrew, Ritchie, M. A., Hunt, L. G., Steane, S. E., Davies, K. G., Bocking, S. P., Rhie, A. G. O., Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

Ritchie, Mark A., Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

post-translational modification

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

prion

Agarwal, Sonya, Döring, Kristina, Gierusz, Leszek A., Iyer, Pooja, Lane, Fiona M., Graham, James F., Goldmann, Wilfred, Pinheiro, Teresa J. T. and Gill, Andrew C. (2015) Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein. Scientific Reports, 5 (1). ISSN 2045-2322

Baskakov, Ilia, Disterer, Petra, Breydo, Leonid, Shaw, Michael, Gill, Andrew, James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

Brimacombe, Debbie B., Bennett, Alan D., Wusteman, Fred S., Gill, Andrew C., Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

Campbell, Lauren, Gill, Andrew, McGovern, Gillian, Jalland, Clara M.O, Hopkins, John, Tranulis, Michael A., Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

Gill, Andrew, Agarwal, Sonya, Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Graham, James F., Kurian, Dominic, Agarwal, Sonya, Toovey, Lorna, Hunt, Lawrence, Kirby, Louise, Pinheiro, Teresa J. T., Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding In vitro and links PrP function and dysfunction. PLoS ONE, 6 (11). e26813. ISSN 1932-6203

Haire, L.F., Whyte, S.M., Vasisht, N., Gill, Andrew C., Verma, C., Dodson, E.J., Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

Hicks, Matthew R., Gill, Andrew C., Bath, Imanpreet K., Rullay, Atvinder K., Sylvester, Ian D., Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Rhie, Alexandre, Kirby, Louise, Sayer, Natalie, Wellesley, Rosanna, Disterer, Petra, Sylvester, Ian, Gill, Andrew C., Hope, James, James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

Sanghera, Narinder, Correia, Bruno E.F.S., Correia, Joana R.S., Ludwig, Christian, Agarwal, Sonya, Nakamura, Hironori K., Kuwata, Kazuo, Samain, Eric, Gill, Andrew, Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

Tahiri-Alaoui, Abdessamad, Gill, Andrew C., Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

Whyte, Sheena M., Sylvester, Ian D., Martin, Stephen R., Gill, Andrew C., Wopfner, Franziska, Schatzl, Hermann M., Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

Young, Duncan S., Meersman, Filip, Oxley, David, Webster, Judith, Gill, Andrew C., Bronstein, Igor, Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

prion protein

Bibby, David F., Gill, Andrew, Kirby, Louise, Farquhar, Christine F., Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Blanch, Ewan W., Gill, Andrew, Rhie, Alexandre G.O., Hope, James, Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

Bocharova, Olga V., Breydo, Leonid, Salnikov, Vadim V., Gill, Andrew and Baskakov, Ilia V. (2005) Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPScfrom sporadic Creutzfeldt-Jakob Disease. Protein Science, 14 (5). pp. 1222-1232. ISSN 1469-896X

Dear, Denise V., Young, Duncan S., Kazlauskaite, Jurate, Meersman, Filip, Oxley, David, Webster, Judith, Pinheiro, Teresa J. T., Gill, Andrew C., Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew, Ritchie, M. A., Hunt, L. G., Steane, S. E., Davies, K. G., Bocking, S. P., Rhie, A. G. O., Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

Kirby, Louise, Goldmann, Wilfred, Houston, Fiona, Gill, Andrew C. and Manson, Jean C. (2006) A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres. Journal of General Virology, 87 (12). pp. 3747-3751. ISSN 0022-1317

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

Ritchie, Mark A., Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

proliferation

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

prolyl hydroxylase

Gill, Andrew, Ritchie, M. A., Hunt, L. G., Steane, S. E., Davies, K. G., Bocking, S. P., Rhie, A. G. O., Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

prophylactic

Brimacombe, Debbie B., Bennett, Alan D., Wusteman, Fred S., Gill, Andrew C., Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

protein cleavage

Campbell, Lauren, Gill, Andrew, McGovern, Gillian, Jalland, Clara M.O, Hopkins, John, Tranulis, Michael A., Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

protein corona

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

protein folding

Baskakov, Ilia, Disterer, Petra, Breydo, Leonid, Shaw, Michael, Gill, Andrew, James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

protein misfolding

Agarwal, Sonya, Döring, Kristina, Gierusz, Leszek A., Iyer, Pooja, Lane, Fiona M., Graham, James F., Goldmann, Wilfred, Pinheiro, Teresa J. T. and Gill, Andrew C. (2015) Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein. Scientific Reports, 5 (1). ISSN 2045-2322

Gill, Andrew, Agarwal, Sonya, Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Graham, James F., Kurian, Dominic, Agarwal, Sonya, Toovey, Lorna, Hunt, Lawrence, Kirby, Louise, Pinheiro, Teresa J. T., Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding In vitro and links PrP function and dysfunction. PLoS ONE, 6 (11). e26813. ISSN 1932-6203

protein phosphorylation

Chen, Hongying, Gill, Andrew C., Dove, Brian K., Emmett, Stevan R., Kemp, C. Fred, Ritchie, Mark A., Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

protein stability

Verma, Rajni, Schwaneberg, Ulrich, Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling Binding Effects of Cobalt(II) Sepulchrate with the Monooxygenase P450 BM-3 Heme Domain Using Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

protein structure

Haire, L.F., Whyte, S.M., Vasisht, N., Gill, Andrew C., Verma, C., Dodson, E.J., Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

protein unfolding

Whyte, Sheena M., Sylvester, Ian D., Martin, Stephen R., Gill, Andrew C., Wopfner, Franziska, Schatzl, Hermann M., Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

prpc

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

raman optical activity

Blanch, Ewan W., Gill, Andrew, Rhie, Alexandre G.O., Hope, James, Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

rat brain tissue

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

rigid loop

Ritchie, Mark A., Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

salmonella

Wood, Michael W., Williams, Christopher, Upadhyay, Abhishek, Gill, Andrew C., Philippe, Didier L., Galyov, Edouard E., van den Elsen, Jean M.H. and Bagby, Stefan (2004) Structural analysis of Salmonella enterica effector protein SopD. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (2). pp. 219-226. ISSN 1570-9639

scrapie

Brimacombe, Debbie B., Bennett, Alan D., Wusteman, Fred S., Gill, Andrew C., Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

selected reaction monitoring

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

serotonin

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

serum igg

Ritchie, Mark A., Deery, Michael J., Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

sleep

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

spd1

Korczynska, Justyna E., Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

strain differentiation

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

stress protection

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

subcellular fractionation

Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

sumoylation

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

surface plasmon resonance

Brimacombe, Debbie B., Bennett, Alan D., Wusteman, Fred S., Gill, Andrew C., Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

tau

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

tauopathies

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

thermodynamic stability

Whyte, Sheena M., Sylvester, Ian D., Martin, Stephen R., Gill, Andrew C., Wopfner, Franziska, Schatzl, Hermann M., Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

transmissible spongiform encephalopathies

Agarwal, Sonya, Döring, Kristina, Gierusz, Leszek A., Iyer, Pooja, Lane, Fiona M., Graham, James F., Goldmann, Wilfred, Pinheiro, Teresa J. T. and Gill, Andrew C. (2015) Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein. Scientific Reports, 5 (1). ISSN 2045-2322

Bibby, David F., Gill, Andrew, Kirby, Louise, Farquhar, Christine F., Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Blanch, Ewan W., Gill, Andrew, Rhie, Alexandre G.O., Hope, James, Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

Bocharova, Olga V., Breydo, Leonid, Salnikov, Vadim V., Gill, Andrew and Baskakov, Ilia V. (2005) Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPScfrom sporadic Creutzfeldt-Jakob Disease. Protein Science, 14 (5). pp. 1222-1232. ISSN 1469-896X

Brimacombe, Debbie B., Bennett, Alan D., Wusteman, Fred S., Gill, Andrew C., Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

Campbell, Lauren, Gill, Andrew, McGovern, Gillian, Jalland, Clara M.O, Hopkins, John, Tranulis, Michael A., Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

Gielbert, Adriana, Davis, Linda A., Sayers, A. Robin, Hope, James, Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew, Agarwal, Sonya, Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

Haire, L.F., Whyte, S.M., Vasisht, N., Gill, Andrew C., Verma, C., Dodson, E.J., Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

Kirby, Louise, Agarwal, Sonya, Graham, James F., Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Kirby, Louise, Goldmann, Wilfred, Houston, Fiona, Gill, Andrew C. and Manson, Jean C. (2006) A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres. Journal of General Virology, 87 (12). pp. 3747-3751. ISSN 0022-1317

Rhie, Alexandre, Kirby, Louise, Sayer, Natalie, Wellesley, Rosanna, Disterer, Petra, Sylvester, Ian, Gill, Andrew C., Hope, James, James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Tahiri-Alaoui, Abdessamad, Gill, Andrew C., Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

Whyte, Sheena M., Sylvester, Ian D., Martin, Stephen R., Gill, Andrew C., Wopfner, Franziska, Schatzl, Hermann M., Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

tumour necrosis factor-alpha (TNF-alpha)

Karwad, Mustafa A., Macpherson, Tara, Wang, Bo, Theophilidou, Elena, Sarmad, Sarir, Barrett, David A., Larvin, Michael, Wright, Karen L., Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

type III secretion

Wood, Michael W., Williams, Christopher, Upadhyay, Abhishek, Gill, Andrew C., Philippe, Didier L., Galyov, Edouard E., van den Elsen, Jean M.H. and Bagby, Stefan (2004) Structural analysis of Salmonella enterica effector protein SopD. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (2). pp. 219-226. ISSN 1570-9639

ubiquitylation

Kontaxi, Christiana, Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

unfolded proteins

McColl, Iain H., Blanch, Ewan W., Gill, Andrew C., Rhie, Alexandre G. O., Ritchie, Mark A., Hecht, Lutz, Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

urea denaturation

Whyte, Sheena M., Sylvester, Ian D., Martin, Stephen R., Gill, Andrew C., Wopfner, Franziska, Schatzl, Hermann M., Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

x-ray crystallography

Haire, L.F., Whyte, S.M., Vasisht, N., Gill, Andrew C., Verma, C., Dodson, E.J., Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836