Items where Subject is "C Biological Sciences > C760 Biomolecular Science"

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AFM Ab-initio computation Aggregation Alternate conformation Animal Biotechnology Biologics BopE Burkholderia pseudomallei CD154 CD40 antigen CD40 ligand Calcium binding Carotenoids Cellular uptake Chicken Complexed structures Coronavirus Cytokines DNA aptamer DNase Drug aggregation Eimeria Evolution Exolytic Exosomes Flow cytometry Fusion protein GASC GPI anchor Glioma Hyaluronate lyase IBV JCCluster Marcus theory Mf2 Molecular dynamics Molecular dynamics simulations NMR structure Natural Compounds Neurodegeneration NotOAChecked Oxidative stress Parasite PrPSc Prion Protein Structure Protein complex Protein misfolding RNA aptamer Raman Spectroscopy Recombinant protein SELEX Secondary Self-diffusion coefficient Size Exclusion SopD Streptomyces coelicolor A3(2) TNFR Trans-epithelial electrical resistance (TEER) Transgenic animals Type III secretion system acetylation adhesion amyloid amyloid fibrils angiotensin-converting enzyme inhibitors antioxidants apicomplexa apple domain arachidonyl ethanolamide or Anandamide (AEA) arginine modification artificial membrane beta-turn biopolymers bovine fetuin captopril cell free conversion circadian rhythm circular dichroism citrulline co-solute effect collision cross section conformational change conformations creutzfeldt jakob disease deimination differential scanning calorimetry differentiation dimyristoylphosphatidylcholine dynamics electron pathways electrospray mass spectrometry fibrillisation gas phase glycation glycosylation gm1 gold nanoparticles guanine nucleotide exchange factor hydroxylysine hydroxyproline ion mobility lipid raft lysozyme; peptidoglycan cleavage; avian gut GH22; crystal structure mass spectrometry mediated electron transfer melatonin membrane anchor metal chelation methylation microneme modular assembly mutation myelin maintenance n-linked glycans neutron reflection nitrative stress nitro-tyrosine nucleocapsid protein o-linked glycosylation oleoylethanolamine (OEA) paired helical filaments palmitoylethanolamine (PEA) pentosan polysulphate peptide fragmentation peptide quantification peroxisome proliferator-activated receptor (PPAR) phage plasminogen ploylysine polymorphism polyproline polyproline helix post translational modification post-translational modification prion prion protein proliferation prolyl hydroxylase prophylactic protein cleavage protein corona protein folding protein misfolding protein phosphorylation protein stability protein structure protein unfolding prpc raman optical activity rat brain tissue rigid loop salmonella scrapie selected reaction monitoring serotonin serum igg sleep spd1 strain differentiation stress protection subcellular fractionation sumoylation surface plasmon resonance tau tauopathies thermodynamic stability transmissible spongiform encephalopathies tumour necrosis factor-alpha (TNF-alpha) type III secretion ubiquitylation unfolded proteins urea denaturation x-ray crystallography
Number of items at this level: 243.

AFM

Caponnetto, Federica and Manini, Ivana and Skrap, Miran and Palmai-Pallag, Timea and Di Loreto, Carla and Beltrami, Antonio Paolo and Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Ab-initio computation

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Aggregation

Dear, Denise V. and Young, Duncan S. and Kazlauskaite, Jurate and Meersman, Filip and Oxley, David and Webster, Judith and Pinheiro, Teresa J. T. and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Alternate conformation

Elmabrouk, Zainab H. and Vincent, Florence and Zhang, Meng and Smith, Nicola L. and Turkenberg, Johan P. and Charnock, Simon J. and Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

Animal Biotechnology

Herron, Lissa R. and Pridans, Clare and Turnbull, Matthew L. and Smith, Nikki and Lillico, Simon and Sherman, Adrian and Gilhooley, Hazel J. and Wear, Martin and Kurian, Dominic and Papadakos, Grigorios and Digard, Paul and Hume, David A. and Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Biologics

Herron, Lissa R. and Pridans, Clare and Turnbull, Matthew L. and Smith, Nikki and Lillico, Simon and Sherman, Adrian and Gilhooley, Hazel J. and Wear, Martin and Kurian, Dominic and Papadakos, Grigorios and Digard, Paul and Hume, David A. and Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

BopE

Upadhyay, Abhishek and Williams, Christopher and Gill, Andrew C. and Philippe, Didier L. and Davis, Kenneth and Taylor, Lowrie A. and Stevens, Mark P. and Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

Burkholderia pseudomallei

Upadhyay, Abhishek and Williams, Christopher and Gill, Andrew C. and Philippe, Didier L. and Davis, Kenneth and Taylor, Lowrie A. and Stevens, Mark P. and Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

CD154

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

CD40 antigen

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

CD40 ligand

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Calcium binding

Periz, Javier and Gill, Andrew C. and Knott, Vroni and Handford, Penny A. and Tomley, Fiona M. (2005) Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. Molecular and Biochemical Parasitology, 143 (2). pp. 192-199. ISSN 0166-6851

Carotenoids

Karki, Khadga Jung and Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Cellular uptake

Caponnetto, Federica and Manini, Ivana and Skrap, Miran and Palmai-Pallag, Timea and Di Loreto, Carla and Beltrami, Antonio Paolo and Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Chicken

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Complexed structures

Elmabrouk, Zainab H. and Vincent, Florence and Zhang, Meng and Smith, Nicola L. and Turkenberg, Johan P. and Charnock, Simon J. and Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

Coronavirus

Chen, Hongying and Gill, Andrew C. and Dove, Brian K. and Emmett, Stevan R. and Kemp, C. Fred and Ritchie, Mark A. and Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

Cytokines

Herron, Lissa R. and Pridans, Clare and Turnbull, Matthew L. and Smith, Nikki and Lillico, Simon and Sherman, Adrian and Gilhooley, Hazel J. and Wear, Martin and Kurian, Dominic and Papadakos, Grigorios and Digard, Paul and Hume, David A. and Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

DNA aptamer

Bibby, David F. and Gill, Andrew and Kirby, Louise and Farquhar, Christine F. and Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

DNase

Korczynska, Justyna E. and Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

Drug aggregation

Karki, Khadga Jung and Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Eimeria

Periz, Javier and Gill, Andrew C. and Hunt, Lawrence and Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

Periz, Javier and Gill, Andrew C. and Knott, Vroni and Handford, Penny A. and Tomley, Fiona M. (2005) Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. Molecular and Biochemical Parasitology, 143 (2). pp. 192-199. ISSN 0166-6851

Evolution

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Exolytic

Elmabrouk, Zainab H. and Vincent, Florence and Zhang, Meng and Smith, Nicola L. and Turkenberg, Johan P. and Charnock, Simon J. and Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

Exosomes

Caponnetto, Federica and Manini, Ivana and Skrap, Miran and Palmai-Pallag, Timea and Di Loreto, Carla and Beltrami, Antonio Paolo and Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Flow cytometry

Caponnetto, Federica and Manini, Ivana and Skrap, Miran and Palmai-Pallag, Timea and Di Loreto, Carla and Beltrami, Antonio Paolo and Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Fusion protein

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

GASC

Caponnetto, Federica and Manini, Ivana and Skrap, Miran and Palmai-Pallag, Timea and Di Loreto, Carla and Beltrami, Antonio Paolo and Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

GPI anchor

Hicks, Matthew R. and Gill, Andrew C. and Bath, Imanpreet K. and Rullay, Atvinder K. and Sylvester, Ian D. and Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X

Glioma

Caponnetto, Federica and Manini, Ivana and Skrap, Miran and Palmai-Pallag, Timea and Di Loreto, Carla and Beltrami, Antonio Paolo and Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Hyaluronate lyase

Elmabrouk, Zainab H. and Vincent, Florence and Zhang, Meng and Smith, Nicola L. and Turkenberg, Johan P. and Charnock, Simon J. and Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

IBV

Chen, Hongying and Gill, Andrew C. and Dove, Brian K. and Emmett, Stevan R. and Kemp, C. Fred and Ritchie, Mark A. and Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

JCCluster

Campbell, Lauren and Gill, Andrew and McGovern, Gillian and Jalland, Clara M.O and Hopkins, John and Tranulis, Michael A. and Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Marcus theory

Verma, Rajni and Schwaneberg, Ulrich and Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling binding effects of Cobalt(II)-Sepulchrate with the monooxygenase P450BM-3 heme domain using molecular dynamics simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

Mf2

Korczynska, Justyna E. and Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

Molecular dynamics

Kirby, Louise and Agarwal, Sonya and Graham, James F. and Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Molecular dynamics simulations

Karki, Khadga Jung and Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

NMR structure

Rhie, Alexandre and Kirby, Louise and Sayer, Natalie and Wellesley, Rosanna and Disterer, Petra and Sylvester, Ian and Gill, Andrew C. and Hope, James and James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Tahiri-Alaoui, Abdessamad and Gill, Andrew C. and Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

Natural Compounds

Karki, Khadga Jung and Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Neurodegeneration

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

NotOAChecked

Karki, Khadga Jung and Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Verma, Rajni and Schwaneberg, Ulrich and Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling binding effects of Cobalt(II)-Sepulchrate with the monooxygenase P450BM-3 heme domain using molecular dynamics simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

Oxidative stress

Dear, Denise V. and Young, Duncan S. and Kazlauskaite, Jurate and Meersman, Filip and Oxley, David and Webster, Judith and Pinheiro, Teresa J. T. and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Parasite

Periz, Javier and Gill, Andrew C. and Hunt, Lawrence and Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

Periz, Javier and Gill, Andrew C. and Knott, Vroni and Handford, Penny A. and Tomley, Fiona M. (2005) Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. Molecular and Biochemical Parasitology, 143 (2). pp. 192-199. ISSN 0166-6851

PrPSc

Bibby, David F. and Gill, Andrew and Kirby, Louise and Farquhar, Christine F. and Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Prion

Kirby, Louise and Agarwal, Sonya and Graham, James F. and Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Protein Structure

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew and Agarwal, Sonya and Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Kirby, Louise and Agarwal, Sonya and Graham, James F. and Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Protein complex

Periz, Javier and Gill, Andrew C. and Hunt, Lawrence and Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

Protein misfolding

Kirby, Louise and Agarwal, Sonya and Graham, James F. and Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Kirby, Louise and Goldmann, Wilfred and Houston, Fiona and Gill, Andrew C. and Manson, Jean C. (2006) A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres. Journal of General Virology, 87 (12). pp. 3747-3751. ISSN 0022-1317

RNA aptamer

Rhie, Alexandre and Kirby, Louise and Sayer, Natalie and Wellesley, Rosanna and Disterer, Petra and Sylvester, Ian and Gill, Andrew C. and Hope, James and James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Raman Spectroscopy

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Recombinant protein

Herron, Lissa R. and Pridans, Clare and Turnbull, Matthew L. and Smith, Nikki and Lillico, Simon and Sherman, Adrian and Gilhooley, Hazel J. and Wear, Martin and Kurian, Dominic and Papadakos, Grigorios and Digard, Paul and Hume, David A. and Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

SELEX

Bibby, David F. and Gill, Andrew and Kirby, Louise and Farquhar, Christine F. and Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Secondary

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew and Agarwal, Sonya and Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Kirby, Louise and Agarwal, Sonya and Graham, James F. and Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Self-diffusion coefficient

Karki, Khadga Jung and Samanta, Susruta and Roccatano, Danilo (2016) Molecular properties of astaxanthin in water/ethanol solutions from computer simulations. The Journal of Physical Chemistry B, 120 (35). pp. 9322-9328. ISSN 1520-6106

Size Exclusion

Periz, Javier and Gill, Andrew C. and Hunt, Lawrence and Brown, Philip and Tomley, Fiona M. (2007) The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. Journal of Biological Chemistry, 282 (23). pp. 16891-16898. ISSN 0021-9258

SopD

Wood, Michael W. and Williams, Christopher and Upadhyay, Abhishek and Gill, Andrew C. and Philippe, Didier L. and Galyov, Edouard E. and van den Elsen, Jean M.H. and Bagby, Stefan (2004) Structural analysis of Salmonella enterica effector protein SopD. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (2). pp. 219-226. ISSN 1570-9639

Streptomyces coelicolor A3(2)

Elmabrouk, Zainab H. and Vincent, Florence and Zhang, Meng and Smith, Nicola L. and Turkenberg, Johan P. and Charnock, Simon J. and Black, Gary W. and Taylor, Edward J. (2011) Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. Proteins: Structure, Function, and Bioinformatics., 79 (3). pp. 965-974. ISSN 0887-3585

TNFR

Tregaskes, Clive A. and Glansbeek, Harrie L. and Gill, Andrew C. and Hunt, Lawrence G. and Burnside, Joan and Young, John R. (2004) Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate. Developmental and Comparative Immunology, 29 (4). pp. 361-374. ISSN 0145-305X

Trans-epithelial electrical resistance (TEER)

Karwad, Mustafa A. and Macpherson, Tara and Wang, Bo and Theophilidou, Elena and Sarmad, Sarir and Barrett, David A. and Larvin, Michael and Wright, Karen L. and Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

Transgenic animals

Herron, Lissa R. and Pridans, Clare and Turnbull, Matthew L. and Smith, Nikki and Lillico, Simon and Sherman, Adrian and Gilhooley, Hazel J. and Wear, Martin and Kurian, Dominic and Papadakos, Grigorios and Digard, Paul and Hume, David A. and Gill, Andrew and Sang, Helen M. (2018) A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (82). p. 82. ISSN 1472-6750

Type III secretion system

Upadhyay, Abhishek and Williams, Christopher and Gill, Andrew C. and Philippe, Didier L. and Davis, Kenneth and Taylor, Lowrie A. and Stevens, Mark P. and Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

acetylation

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

adhesion

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

amyloid

Baskakov, Ilia and Disterer, Petra and Breydo, Leonid and Shaw, Michael and Gill, Andrew and James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

Whyte, Sheena M. and Sylvester, Ian D. and Martin, Stephen R. and Gill, Andrew C. and Wopfner, Franziska and Schatzl, Hermann M. and Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

amyloid fibrils

Blanch, Ewan W. and Gill, Andrew and Rhie, Alexandre G.O. and Hope, James and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

angiotensin-converting enzyme inhibitors

Tereza Fernandez, M. and Manuela Silva, M. and Mira, Lurdes and Helena Florêncio, M. and Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

antioxidants

Tereza Fernandez, M. and Manuela Silva, M. and Mira, Lurdes and Helena Florêncio, M. and Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

apicomplexa

Brown, Philip J. and Gill, Andrew and Nugent, Philip G. and McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

apple domain

Brown, Philip J. and Gill, Andrew and Nugent, Philip G. and McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

arachidonyl ethanolamide or Anandamide (AEA)

Karwad, Mustafa A. and Macpherson, Tara and Wang, Bo and Theophilidou, Elena and Sarmad, Sarir and Barrett, David A. and Larvin, Michael and Wright, Karen L. and Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

arginine modification

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

artificial membrane

Hollinshead, Clare M and Hanna, M and Barlow, D J and De Biasi, V and Bucknall, D G and Camilleri, P and Hutt, A J and Lawrence, M J and Lu, J and Su, T J (1999) Determination of the structure of a novel type of artificial membrane by neutron reflectivity. Journal of Pharmacy and Phamacology, 51 (S). p. 90. ISSN 0022-3573

beta-turn

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

biopolymers

Gill, Andrew and Jennings, Keith R. and Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

bovine fetuin

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

captopril

Tereza Fernandez, M. and Manuela Silva, M. and Mira, Lurdes and Helena Florêncio, M. and Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

cell free conversion

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

circadian rhythm

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

circular dichroism

Upadhyay, Abhishek and Williams, Christopher and Gill, Andrew C. and Philippe, Didier L. and Davis, Kenneth and Taylor, Lowrie A. and Stevens, Mark P. and Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

citrulline

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

co-solute effect

Verma, Rajni and Schwaneberg, Ulrich and Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling binding effects of Cobalt(II)-Sepulchrate with the monooxygenase P450BM-3 heme domain using molecular dynamics simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

collision cross section

Gill, Andrew and Jennings, Keith R. and Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

conformational change

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

conformations

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

creutzfeldt jakob disease

Bocharova, Olga V. and Breydo, Leonid and Salnikov, Vadim V. and Gill, Andrew and Baskakov, Ilia V. (2005) Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPScfrom sporadic Creutzfeldt-Jakob Disease. Protein Science, 14 (5). pp. 1222-1232. ISSN 1469-896X

Haire, L.F. and Whyte, S.M. and Vasisht, N. and Gill, Andrew C. and Verma, C. and Dodson, E.J. and Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

Rhie, Alexandre and Kirby, Louise and Sayer, Natalie and Wellesley, Rosanna and Disterer, Petra and Sylvester, Ian and Gill, Andrew C. and Hope, James and James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

deimination

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

differential scanning calorimetry

Upadhyay, Abhishek and Williams, Christopher and Gill, Andrew C. and Philippe, Didier L. and Davis, Kenneth and Taylor, Lowrie A. and Stevens, Mark P. and Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

differentiation

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

dimyristoylphosphatidylcholine

Hollinshead, Clare M and Hanna, M and Barlow, D J and De Biasi, V and Bucknall, D G and Camilleri, P and Hutt, A J and Lawrence, M J and Lu, J and Su, T J (1999) Determination of the structure of a novel type of artificial membrane by neutron reflectivity. Journal of Pharmacy and Phamacology, 51 (S). p. 90. ISSN 0022-3573

dynamics

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

electron pathways

Verma, Rajni and Schwaneberg, Ulrich and Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling binding effects of Cobalt(II)-Sepulchrate with the monooxygenase P450BM-3 heme domain using molecular dynamics simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

electrospray mass spectrometry

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

Tereza Fernandez, M. and Manuela Silva, M. and Mira, Lurdes and Helena Florêncio, M. and Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

fibrillisation

Campbell, Lauren and Gill, Andrew and McGovern, Gillian and Jalland, Clara M.O and Hopkins, John and Tranulis, Michael A. and Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Graham, James F. and Kurian, Dominic and Agarwal, Sonya and Toovey, Lorna and Hunt, Lawrence and Kirby, Louise and Pinheiro, Teresa J. T. and Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding In vitro and links PrP function and dysfunction. PLoS ONE, 6 (11). e26813. ISSN 1932-6203

gas phase

Gill, Andrew and Jennings, Keith R. and Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

glycation

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

glycosylation

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

gm1

Sanghera, Narinder and Correia, Bruno E.F.S. and Correia, Joana R.S. and Ludwig, Christian and Agarwal, Sonya and Nakamura, Hironori K. and Kuwata, Kazuo and Samain, Eric and Gill, Andrew and Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

gold nanoparticles

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

guanine nucleotide exchange factor

Upadhyay, Abhishek and Williams, Christopher and Gill, Andrew C. and Philippe, Didier L. and Davis, Kenneth and Taylor, Lowrie A. and Stevens, Mark P. and Galyov, Edouard E. and Bagby, Stefan (2004) Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (1). pp. 111-119. ISSN 1570-9639

hydroxylysine

Ritchie, Mark A. and Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

hydroxyproline

Gill, Andrew and Ritchie, M. A. and Hunt, L. G. and Steane, S. E. and Davies, K. G. and Bocking, S. P. and Rhie, A. G. O. and Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

ion mobility

Gill, Andrew and Jennings, Keith R. and Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

lipid raft

Sanghera, Narinder and Correia, Bruno E.F.S. and Correia, Joana R.S. and Ludwig, Christian and Agarwal, Sonya and Nakamura, Hironori K. and Kuwata, Kazuo and Samain, Eric and Gill, Andrew and Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

lysozyme; peptidoglycan cleavage; avian gut GH22; crystal structure

Taylor, Edward and Skjøt, Michael and Skov, Lars K. and Klausen, Mikkel and De Maria, Leonardo and Gippert, Garry P. and Turkenburg, Johan P. and Davies, Gideon J. and Wilson, Keith S. (2019) The C-Type Lysozyme from the upper Gastrointestinal Tract of Opisthocomus hoatzin, the Stinkbird. International Journal of Molecular Sciences, 20 (22). ISSN 1422-0067

mass spectrometry

Brown, Philip J. and Gill, Andrew and Nugent, Philip G. and McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

Chen, Hongying and Gill, Andrew C. and Dove, Brian K. and Emmett, Stevan R. and Kemp, C. Fred and Ritchie, Mark A. and Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

Gill, Andrew and Jennings, Keith R. and Wyttenbach, Thomas and Bowers, Michael T. (2000) Conformations of biopolymers in the gas phase: a new mass spectrometric method. International Journal of Mass Spectrometry, 195-19 . pp. 685-697. ISSN 1387-3806

mediated electron transfer

Verma, Rajni and Schwaneberg, Ulrich and Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling binding effects of Cobalt(II)-Sepulchrate with the monooxygenase P450BM-3 heme domain using molecular dynamics simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

melatonin

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

membrane anchor

Hicks, Matthew R. and Gill, Andrew C. and Bath, Imanpreet K. and Rullay, Atvinder K. and Sylvester, Ian D. and Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X

metal chelation

Tereza Fernandez, M. and Manuela Silva, M. and Mira, Lurdes and Helena Florêncio, M. and Gill, Andrew and Jennings, Keith R. (1998) Iron and copper complexation by angiotensin-converting enzyme inhibitors. A study by ultraviolet spectroscopy and electrospray mass spectrometry. Journal of Inorganic Biochemistry, 71 (1-2). pp. 93-98. ISSN 0162-0134

methylation

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

microneme

Brown, Philip J. and Gill, Andrew and Nugent, Philip G. and McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

modular assembly

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

mutation

Tahiri-Alaoui, Abdessamad and Gill, Andrew C. and Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

myelin maintenance

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

n-linked glycans

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

neutron reflection

Hollinshead, Clare M and Hanna, M and Barlow, D J and De Biasi, V and Bucknall, D G and Camilleri, P and Hutt, A J and Lawrence, M J and Lu, J and Su, T J (1999) Determination of the structure of a novel type of artificial membrane by neutron reflectivity. Journal of Pharmacy and Phamacology, 51 (S). p. 90. ISSN 0022-3573

nitrative stress

Dear, Denise V. and Young, Duncan S. and Kazlauskaite, Jurate and Meersman, Filip and Oxley, David and Webster, Judith and Pinheiro, Teresa J. T. and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

nitro-tyrosine

Dear, Denise V. and Young, Duncan S. and Kazlauskaite, Jurate and Meersman, Filip and Oxley, David and Webster, Judith and Pinheiro, Teresa J. T. and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

nucleocapsid protein

Chen, Hongying and Gill, Andrew C. and Dove, Brian K. and Emmett, Stevan R. and Kemp, C. Fred and Ritchie, Mark A. and Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

o-linked glycosylation

Ritchie, Mark A. and Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

oleoylethanolamine (OEA)

Karwad, Mustafa A. and Macpherson, Tara and Wang, Bo and Theophilidou, Elena and Sarmad, Sarir and Barrett, David A. and Larvin, Michael and Wright, Karen L. and Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

paired helical filaments

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

palmitoylethanolamine (PEA)

Karwad, Mustafa A. and Macpherson, Tara and Wang, Bo and Theophilidou, Elena and Sarmad, Sarir and Barrett, David A. and Larvin, Michael and Wright, Karen L. and Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

pentosan polysulphate

Brimacombe, Debbie B. and Bennett, Alan D. and Wusteman, Fred S. and Gill, Andrew C. and Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

peptide fragmentation

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

peptide quantification

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

peroxisome proliferator-activated receptor (PPAR)

Karwad, Mustafa A. and Macpherson, Tara and Wang, Bo and Theophilidou, Elena and Sarmad, Sarir and Barrett, David A. and Larvin, Michael and Wright, Karen L. and Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

phage

Korczynska, Justyna E. and Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

plasminogen

Brown, Philip J. and Gill, Andrew and Nugent, Philip G. and McVey, John H. and Tomley, Fiona M. (2001) Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters, 497 (1). pp. 31-38. ISSN 0014-5793

ploylysine

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

polymorphism

Baskakov, Ilia and Disterer, Petra and Breydo, Leonid and Shaw, Michael and Gill, Andrew and James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

Tahiri-Alaoui, Abdessamad and Gill, Andrew C. and Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

polyproline

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

polyproline helix

Blanch, Ewan W. and Gill, Andrew and Rhie, Alexandre G.O. and Hope, James and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

Gill, Andrew and Ritchie, M. A. and Hunt, L. G. and Steane, S. E. and Davies, K. G. and Bocking, S. P. and Rhie, A. G. O. and Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

post translational modification

Dear, Denise V. and Young, Duncan S. and Kazlauskaite, Jurate and Meersman, Filip and Oxley, David and Webster, Judith and Pinheiro, Teresa J. T. and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Gill, Andrew and Ritchie, M. A. and Hunt, L. G. and Steane, S. E. and Davies, K. G. and Bocking, S. P. and Rhie, A. G. O. and Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

Ritchie, Mark A. and Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

post-translational modification

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

prion

Agarwal, Sonya and Döring, Kristina and Gierusz, Leszek A. and Iyer, Pooja and Lane, Fiona M. and Graham, James F. and Goldmann, Wilfred and Pinheiro, Teresa J. T. and Gill, Andrew C. (2015) Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein. Scientific Reports, 5 (1). ISSN 2045-2322

Baskakov, Ilia and Disterer, Petra and Breydo, Leonid and Shaw, Michael and Gill, Andrew and James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

Brimacombe, Debbie B. and Bennett, Alan D. and Wusteman, Fred S. and Gill, Andrew C. and Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

Campbell, Lauren and Gill, Andrew and McGovern, Gillian and Jalland, Clara M.O and Hopkins, John and Tranulis, Michael A. and Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

Gill, Andrew and Agarwal, Sonya and Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Graham, James F. and Kurian, Dominic and Agarwal, Sonya and Toovey, Lorna and Hunt, Lawrence and Kirby, Louise and Pinheiro, Teresa J. T. and Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding In vitro and links PrP function and dysfunction. PLoS ONE, 6 (11). e26813. ISSN 1932-6203

Haire, L.F. and Whyte, S.M. and Vasisht, N. and Gill, Andrew C. and Verma, C. and Dodson, E.J. and Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

Hicks, Matthew R. and Gill, Andrew C. and Bath, Imanpreet K. and Rullay, Atvinder K. and Sylvester, Ian D. and Crout, David H. and Pinheiro, Teresa J. T. (2006) Synthesis and structural characterization of a mimetic membrane-anchored prion protein. FEBS Journal, 273 (6). pp. 1285-1299. ISSN 1742-464X

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

Rhie, Alexandre and Kirby, Louise and Sayer, Natalie and Wellesley, Rosanna and Disterer, Petra and Sylvester, Ian and Gill, Andrew C. and Hope, James and James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

Sanghera, Narinder and Correia, Bruno E.F.S. and Correia, Joana R.S. and Ludwig, Christian and Agarwal, Sonya and Nakamura, Hironori K. and Kuwata, Kazuo and Samain, Eric and Gill, Andrew and Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

Tahiri-Alaoui, Abdessamad and Gill, Andrew C. and Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

Whyte, Sheena M. and Sylvester, Ian D. and Martin, Stephen R. and Gill, Andrew C. and Wopfner, Franziska and Schatzl, Hermann M. and Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

Young, Duncan S. and Meersman, Filip and Oxley, David and Webster, Judith and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. and Dear, Denise V. (2009) Effect of enzymatic deimination on the conformation of recombinant prion protein. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1794 (8). pp. 1123-1133. ISSN 1570-9639

prion protein

Bibby, David F. and Gill, Andrew and Kirby, Louise and Farquhar, Christine F. and Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Blanch, Ewan W. and Gill, Andrew and Rhie, Alexandre G.O. and Hope, James and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

Bocharova, Olga V. and Breydo, Leonid and Salnikov, Vadim V. and Gill, Andrew and Baskakov, Ilia V. (2005) Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPScfrom sporadic Creutzfeldt-Jakob Disease. Protein Science, 14 (5). pp. 1222-1232. ISSN 1469-896X

Dear, Denise V. and Young, Duncan S. and Kazlauskaite, Jurate and Meersman, Filip and Oxley, David and Webster, Judith and Pinheiro, Teresa J. T. and Gill, Andrew C. and Bronstein, Igor and Lowe, Christopher R. (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774 (7). pp. 792-802. ISSN 1570-9639

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew and Ritchie, M. A. and Hunt, L. G. and Steane, S. E. and Davies, K. G. and Bocking, S. P. and Rhie, A. G. O. and Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

Kirby, Louise and Goldmann, Wilfred and Houston, Fiona and Gill, Andrew C. and Manson, Jean C. (2006) A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres. Journal of General Virology, 87 (12). pp. 3747-3751. ISSN 0022-1317

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

Ritchie, Mark A. and Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

proliferation

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

prolyl hydroxylase

Gill, Andrew and Ritchie, M. A. and Hunt, L. G. and Steane, S. E. and Davies, K. G. and Bocking, S. P. and Rhie, A. G. O. and Bennett, A. D. and Hope, J. (2000) Post-translational hydroxylation at the N-terminus of the prion protein reveals presence of PPII structure in vivo. The EMBO Journal, 19 (20). pp. 5324-5331. ISSN 0261-4189

prophylactic

Brimacombe, Debbie B. and Bennett, Alan D. and Wusteman, Fred S. and Gill, Andrew C. and Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

protein cleavage

Campbell, Lauren and Gill, Andrew and McGovern, Gillian and Jalland, Clara M.O and Hopkins, John and Tranulis, Michael A. and Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

protein corona

Ferrari, Enrico (2018) A plug and play approach for the decoration of nanoparticles with recombinant proteins. Nanomedicine, 13 (20). pp. 2547-2550. ISSN 1743-5889

protein folding

Baskakov, Ilia and Disterer, Petra and Breydo, Leonid and Shaw, Michael and Gill, Andrew and James, William and Tahiri-Alaoui, Abdessamad (2005) The presence of valine at residue 129 in human prion protein accelerates amyloid formation. FEBS Letters, 579 (12). pp. 2589-2596. ISSN 0014-5793

protein misfolding

Agarwal, Sonya and Döring, Kristina and Gierusz, Leszek A. and Iyer, Pooja and Lane, Fiona M. and Graham, James F. and Goldmann, Wilfred and Pinheiro, Teresa J. T. and Gill, Andrew C. (2015) Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein. Scientific Reports, 5 (1). ISSN 2045-2322

Gill, Andrew and Agarwal, Sonya and Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

Graham, James F. and Kurian, Dominic and Agarwal, Sonya and Toovey, Lorna and Hunt, Lawrence and Kirby, Louise and Pinheiro, Teresa J. T. and Banner, Steven J. and Gill, Andrew C. (2011) Na+/K+-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding In vitro and links PrP function and dysfunction. PLoS ONE, 6 (11). e26813. ISSN 1932-6203

protein phosphorylation

Chen, Hongying and Gill, Andrew C. and Dove, Brian K. and Emmett, Stevan R. and Kemp, C. Fred and Ritchie, Mark A. and Dee, Michael and Hiscox, Julian A. (2005) Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. Journal of Virology, 79 (2). pp. 1164-1179. ISSN 0022-538X

protein stability

Verma, Rajni and Schwaneberg, Ulrich and Holtmann, Dirk and Roccatano, Danilo (2015) Unraveling binding effects of Cobalt(II)-Sepulchrate with the monooxygenase P450BM-3 heme domain using molecular dynamics simulations. Journal of Chemical Theory and Computation, 12 (1). pp. 353-363. ISSN 1549-9618

protein structure

Haire, L.F. and Whyte, S.M. and Vasisht, N. and Gill, Andrew C. and Verma, C. and Dodson, E.J. and Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

protein unfolding

Whyte, Sheena M. and Sylvester, Ian D. and Martin, Stephen R. and Gill, Andrew C. and Wopfner, Franziska and Schatzl, Hermann M. and Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

prpc

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

raman optical activity

Blanch, Ewan W. and Gill, Andrew and Rhie, Alexandre G.O. and Hope, James and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

rat brain tissue

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

rigid loop

Ritchie, Mark A. and Hunt, Lawrence G. and Gill, Andrew C. (2012) Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP. International Journal of Mass Spectrometry, 345-34 . pp. 132-141. ISSN 1387-3806

salmonella

Wood, Michael W. and Williams, Christopher and Upadhyay, Abhishek and Gill, Andrew C. and Philippe, Didier L. and Galyov, Edouard E. and van den Elsen, Jean M.H. and Bagby, Stefan (2004) Structural analysis of Salmonella enterica effector protein SopD. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (2). pp. 219-226. ISSN 1570-9639

scrapie

Brimacombe, Debbie B. and Bennett, Alan D. and Wusteman, Fred S. and Gill, Andrew C. and Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

selected reaction monitoring

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

serotonin

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

serum igg

Ritchie, Mark A. and Deery, Michael J. and Lilley, Kathryn and Gill, Andrew (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. Journal of the American Society for Mass Spectrometry, 13 (9). pp. 1065-1077. ISSN 1044-0305

sleep

Roguski, Amber and Gill, Andrew C. (2017) The role of the mammalian prion protein in the control of sleep. Pathogens, 6 (4). p. 58. ISSN 2076-0817

spd1

Korczynska, Justyna E. and Turkenburg, John P. and Taylor, Edward J. (2012) The structural characterisation of a prophage encoded extracellular DNase from Streptococcus pyogenes. Nucleic Acids Research, 40 (2). pp. 928-938. ISSN 0305-1048

strain differentiation

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

stress protection

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

subcellular fractionation

Graham, James F. and Agarwal, Sonya and Kurian, Dominic and Kirby, Louise and Pinheiro, Teresa J. T. and Gill, Andrew C. (2010) Low density subcellular fractions enhance disease-specific prion protein misfolding. Journal of Biological Chemistry, 285 (13). pp. 9868-9880. ISSN 1083-351X

sumoylation

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

surface plasmon resonance

Brimacombe, Debbie B. and Bennett, Alan D. and Wusteman, Fred S. and Gill, Andrew C. and Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

tau

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

tauopathies

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

thermodynamic stability

Whyte, Sheena M. and Sylvester, Ian D. and Martin, Stephen R. and Gill, Andrew C. and Wopfner, Franziska and Schatzl, Hermann M. and Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

transmissible spongiform encephalopathies

Agarwal, Sonya and Döring, Kristina and Gierusz, Leszek A. and Iyer, Pooja and Lane, Fiona M. and Graham, James F. and Goldmann, Wilfred and Pinheiro, Teresa J. T. and Gill, Andrew C. (2015) Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein. Scientific Reports, 5 (1). ISSN 2045-2322

Bibby, David F. and Gill, Andrew and Kirby, Louise and Farquhar, Christine F. and Bruce, Moira E. and Garson, Jeremy A. (2008) Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteins. Journal of Virological Methods, 151 (1). pp. 107-115. ISSN 0166-0934

Blanch, Ewan W. and Gill, Andrew and Rhie, Alexandre G.O. and Hope, James and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2004) Raman Optical Activity Demonstrates Poly(l-proline) II Helix in the N-terminal Region of the Ovine Prion Protein: Implications for Function and Misfunction. Journal of Molecular Biology, 343 (2). pp. 467-476. ISSN 0022-2836

Bocharova, Olga V. and Breydo, Leonid and Salnikov, Vadim V. and Gill, Andrew and Baskakov, Ilia V. (2005) Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPScfrom sporadic Creutzfeldt-Jakob Disease. Protein Science, 14 (5). pp. 1222-1232. ISSN 1469-896X

Brimacombe, Debbie B. and Bennett, Alan D. and Wusteman, Fred S. and Gill, Andrew C. and Dann, Janine C. and Bostock, Christopher J. (1999) Characterization and polyanion-binding properties of purified recombinant prion protein. Biochemical Journal, 342 (3). p. 605. ISSN 0264-6021

Campbell, Lauren and Gill, Andrew and McGovern, Gillian and Jalland, Clara M.O and Hopkins, John and Tranulis, Michael A. and Hunter, Nora and Goldmann, Wilfred (2013) The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1832 (6). pp. 826-836. ISSN 0925-4439

Castle, Andrew R. and Gill, Andrew C. (2017) Physiological functions of the cellular prion protein. Frontiers in Molecular Biosciences, 4 (19). ISSN 2296-889X

Gielbert, Adriana and Davis, Linda A. and Sayers, A. Robin and Hope, James and Gill, Andrew and Sauer, Maurice J. (2008) High-resolution differentiation of transmissible spongiform encephalopathy strains by quantitative N-terminal amino acid profiling (N-TAAP) of PK-digested abnormal prion protein. Journal of Mass Spectrometry, 44 (3). pp. 384-396. ISSN 1096-9888

Gill, Andrew and Agarwal, Sonya and Pinheiro, Teresa J.T. and Graham, James F. (2010) Structural requirements for efficient prion protein conversion. Prion, 4 (4). pp. 235-243. ISSN 1933-6896

Gill, Andrew C. (2014) β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides. PLoS ONE, 9 (1). e87354. ISSN 1932-6203

Haire, L.F. and Whyte, S.M. and Vasisht, N. and Gill, Andrew C. and Verma, C. and Dodson, E.J. and Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

Kirby, Louise and Agarwal, Sonya and Graham, James F. and Goldmann, Wilfred and Gill, Andrew (2010) Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants. Biochemistry, 49 (7). pp. 1448-1459. ISSN 0006-2960

Kirby, Louise and Goldmann, Wilfred and Houston, Fiona and Gill, Andrew C. and Manson, Jean C. (2006) A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres. Journal of General Virology, 87 (12). pp. 3747-3751. ISSN 0022-1317

Rhie, Alexandre and Kirby, Louise and Sayer, Natalie and Wellesley, Rosanna and Disterer, Petra and Sylvester, Ian and Gill, Andrew C. and Hope, James and James, William and Tahiri-Alaoui, Abdessamad (2003) Characterization of 2′-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion. Journal of Biological Chemistry, 278 (41). pp. 39697-39705. ISSN 0021-9258

Tahiri-Alaoui, Abdessamad and Gill, Andrew C. and Disterer, Petra and James, William (2004) Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant. Journal of Biological Chemistry, 279 (30). pp. 31390-31397. ISSN 0021-9258

Whyte, Sheena M. and Sylvester, Ian D. and Martin, Stephen R. and Gill, Andrew C. and Wopfner, Franziska and Schatzl, Hermann M. and Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

tumour necrosis factor-alpha (TNF-alpha)

Karwad, Mustafa A. and Macpherson, Tara and Wang, Bo and Theophilidou, Elena and Sarmad, Sarir and Barrett, David A. and Larvin, Michael and Wright, Karen L. and Lund, Jonathan N. and O’Sullivan, Saoirse E. (2017) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα. The FASEB Journal, 31 (2). pp. 469-481. ISSN 0892-6638

type III secretion

Wood, Michael W. and Williams, Christopher and Upadhyay, Abhishek and Gill, Andrew C. and Philippe, Didier L. and Galyov, Edouard E. and van den Elsen, Jean M.H. and Bagby, Stefan (2004) Structural analysis of Salmonella enterica effector protein SopD. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1698 (2). pp. 219-226. ISSN 1570-9639

ubiquitylation

Kontaxi, Christiana and Piccardo, Pedro and Gill, Andrew C. (2017) Lysine-directed post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Frontiers in Molecular Biosciences, 4 (56). ISSN 2296-889X

unfolded proteins

McColl, Iain H. and Blanch, Ewan W. and Gill, Andrew C. and Rhie, Alexandre G. O. and Ritchie, Mark A. and Hecht, Lutz and Nielsen, Kurt and Barron, Laurence D. (2003) A new perspective on β-sheet structures using vibrational Raman Optical Activity: from poly(l-lysine) to the prion protein. Journal of the American Chemical Society, 125 (33). pp. 10019-10026. ISSN 0002-7863

urea denaturation

Whyte, Sheena M. and Sylvester, Ian D. and Martin, Stephen R. and Gill, Andrew C. and Wopfner, Franziska and Schatzl, Hermann M. and Dodson, Guy G. and Bayley, Peter M. (2003) Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant. Biochemical Journal, 373 (2). pp. 485-494. ISSN 0264-6021

x-ray crystallography

Haire, L.F. and Whyte, S.M. and Vasisht, N. and Gill, Andrew C. and Verma, C. and Dodson, E.J. and Dodson, G.G. and Bayley, P.M. (2004) The crystal structure of the globular domain of sheep prion protein. Journal of Molecular Biology, 336 (5). pp. 1175-1183. ISSN 0022-2836

This list was generated on Tue Nov 19 14:10:58 2019 GMT.