Animal RNA virus

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Mohapatra, J. K. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2005) Genetic comparison of large fragment of the 5'untranslated region among foot-and-mouth disease viruses with special reference to serotype Asia1. Archives of Virology, 150 (11). pp. 2217-2239. ISSN 0304-8608

Animal model

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Research, 75 (1). pp. 30-35. ISSN 0166-3542

Antiviral

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Research, 75 (1). pp. 30-35. ISSN 0166-3542

Antivirals

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) Single amino acid substitutions in the HSV-1 helicase protein that confer resistance to the helicase-primase inhibitor BAY 57-1293 are associated with increased or decreased virus growth characteristics in tissue culture. Archives of Virology, 152 (8). pp. 1489-1500. ISSN 0304-8608

Biswas, Subhajit and Swift, Mihaiela and Field, Hugh J. (2007) High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1. Antiviral Chemistry & Chemotherapy, 18 (1). pp. 13-23. ISSN 0956-3202

Apoptosis

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

Asia 1 serotype

Mohapatra, Jajati K. and Sanyal, Aniket and Hemadri, Divakar and Tosh, Chakradhar and Biswas, Subhajit and Knowles, Nick J. and Rasool, Thaha J. and Bandyopadhyay, Santanu K. and Pattnaik, Bramhadev (2008) Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades. Virus Research, 136 (1-2). pp. 16-29. ISSN 0168-1702

BAY 57-1293

Biswas, Subhajit and Kleymann, Gerald and Swift, Mihaiela and Tiley, Laurence S. and Lyall, Jonathan and Aguirre-Hernández, Jesús and Field, Hugh J. (2008) A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target. Journal of Antimicrobial Chemotherapy, 61 (5). pp. 1044-1047. ISSN 0305-7453

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

BCR

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

BILS 22 BS

Biswas, Subhajit and Kleymann, Gerald and Swift, Mihaiela and Tiley, Laurence S. and Lyall, Jonathan and Aguirre-Hernández, Jesús and Field, Hugh J. (2008) A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target. Journal of Antimicrobial Chemotherapy, 61 (5). pp. 1044-1047. ISSN 0305-7453

Clinical virology

Biswas, Subhajit and Smith, Christopher and Field, Hugh J. (2007) Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1. The Journal of Antimicrobial Chemotherapy, 60 (2). pp. 274-279. ISSN 0305-7453

DNA Virus

Field, Hugh J. and Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

DNA virus

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) Single amino acid substitutions in the HSV-1 helicase protein that confer resistance to the helicase-primase inhibitor BAY 57-1293 are associated with increased or decreased virus growth characteristics in tissue culture. Archives of Virology, 152 (8). pp. 1489-1500. ISSN 0304-8608

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Research, 75 (1). pp. 30-35. ISSN 0166-3542

Biswas, Subhajit and Smith, Christopher and Field, Hugh J. (2007) Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1. The Journal of Antimicrobial Chemotherapy, 60 (2). pp. 274-279. ISSN 0305-7453

Biswas, Subhajit and Swift, Mihaiela and Field, Hugh J. (2007) High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1. Antiviral Chemistry & Chemotherapy, 18 (1). pp. 13-23. ISSN 0956-3202

HPI-resistant mutants

Biswas, Subhajit and Field, Hugh J. (2011) Helicase–primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus. In: Antiviral Drug Strategies. Methods and Principles in Medicinal Chemistry . Wiley-VCH Verlag GmbH & Co. KGaA, pp. 129-146. ISBN 9783527635955, 9783527326969

HSV

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

HSV-1

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

Hepatocytes

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

India

Mohapatra, Jajati K. and Sanyal, Aniket and Hemadri, Divakar and Tosh, Chakradhar and Biswas, Subhajit and Knowles, Nick J. and Rasool, Thaha J. and Bandyopadhyay, Santanu K. and Pattnaik, Bramhadev (2008) Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades. Virus Research, 136 (1-2). pp. 16-29. ISSN 0168-1702

Inflammation

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

K13

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

KSHV

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

Liver

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

Mouse model

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Research, 75 (1). pp. 30-35. ISSN 0166-3542

Mutlicentric Castleman Disease

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

NEMO

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

RNA structure

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Mohapatra, J. K. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2005) Genetic comparison of large fragment of the 5'untranslated region among foot-and-mouth disease viruses with special reference to serotype Asia1. Archives of Virology, 150 (11). pp. 2217-2239. ISSN 0304-8608

RNA virus

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Gupta, S. K. and Mittal, M. and Mohapatra, J. K. and Sabarinath, G. P. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2004) Sequence analysis of Vpg protein of Asia-1 field isolates of Foot and Mouth Disease Virus in India. Journal of Animal and Veterinary Advances, 3 (8). pp. 522-526. ISSN 1680-5593

TRAF

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

Ubiquitin

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

Veterinary Antivirals

Field, Hugh J. and Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

Veterinary Medicine

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Mohapatra, J. K. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2005) Genetic comparison of large fragment of the 5'untranslated region among foot-and-mouth disease viruses with special reference to serotype Asia1. Archives of Virology, 150 (11). pp. 2217-2239. ISSN 0304-8608

Virology

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Mohapatra, J. K. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2005) Genetic comparison of large fragment of the 5'untranslated region among foot-and-mouth disease viruses with special reference to serotype Asia1. Archives of Virology, 150 (11). pp. 2217-2239. ISSN 0304-8608

Field, Hugh J. and Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

Virus evolution

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Gupta, S. K. and Mittal, M. and Mohapatra, J. K. and Sabarinath, G. P. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2004) Sequence analysis of Vpg protein of Asia-1 field isolates of Foot and Mouth Disease Virus in India. Journal of Animal and Veterinary Advances, 3 (8). pp. 522-526. ISSN 1680-5593

Biswas, Subhajit and Smith, Christopher and Field, Hugh J. (2007) Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1. The Journal of Antimicrobial Chemotherapy, 60 (2). pp. 274-279. ISSN 0305-7453

Biswas, Subhajit and Swift, Mihaiela and Field, Hugh J. (2007) High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1. Antiviral Chemistry & Chemotherapy, 18 (1). pp. 13-23. ISSN 0956-3202

Virus mutation

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) Single amino acid substitutions in the HSV-1 helicase protein that confer resistance to the helicase-primase inhibitor BAY 57-1293 are associated with increased or decreased virus growth characteristics in tissue culture. Archives of Virology, 152 (8). pp. 1489-1500. ISSN 0304-8608

Biswas, Subhajit and Smith, Christopher and Field, Hugh J. (2007) Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1. The Journal of Antimicrobial Chemotherapy, 60 (2). pp. 274-279. ISSN 0305-7453

Virus pathogenesis

Biswas, Subhajit and Jennens, Lyn and Field, Hugh J. (2007) The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Research, 75 (1). pp. 30-35. ISSN 0166-3542

Virus plaque assay

Biswas, Subhajit and Swift, Mihaiela and Field, Hugh J. (2007) High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1. Antiviral Chemistry & Chemotherapy, 18 (1). pp. 13-23. ISSN 0956-3202

antiviral

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

antiviral resistance

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

antivirals

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

bmjdoi

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

bmjolf

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

cell culture

Biswas, Subhajit and Swift, Mihaiela and Field, Hugh J. (2007) High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1. Antiviral Chemistry & Chemotherapy, 18 (1). pp. 13-23. ISSN 0956-3202

cross-resistance

Biswas, Subhajit and Field, Hugh J. (2011) Helicase–primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus. In: Antiviral Drug Strategies. Methods and Principles in Medicinal Chemistry . Wiley-VCH Verlag GmbH & Co. KGaA, pp. 129-146. ISBN 9783527635955, 9783527326969

drug-resistance

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

epidemiology

Mohapatra, Jajati K. and Sanyal, Aniket and Hemadri, Divakar and Tosh, Chakradhar and Biswas, Subhajit and Knowles, Nick J. and Rasool, Thaha J. and Bandyopadhyay, Santanu K. and Pattnaik, Bramhadev (2008) Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades. Virus Research, 136 (1-2). pp. 16-29. ISSN 0168-1702

foot-and-mouth disease

Mohapatra, Jajati K. and Sanyal, Aniket and Hemadri, Divakar and Tosh, Chakradhar and Biswas, Subhajit and Knowles, Nick J. and Rasool, Thaha J. and Bandyopadhyay, Santanu K. and Pattnaik, Bramhadev (2008) Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades. Virus Research, 136 (1-2). pp. 16-29. ISSN 0168-1702

growth curve

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

helicase

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

helicase–primase complex

Biswas, Subhajit and Field, Hugh J. (2011) Helicase–primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus. In: Antiviral Drug Strategies. Methods and Principles in Medicinal Chemistry . Wiley-VCH Verlag GmbH & Co. KGaA, pp. 129-146. ISBN 9783527635955, 9783527326969

helicase–primase inhibitor

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

herpes simplex

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

herpes simplex virus

Biswas, Subhajit and Kleymann, Gerald and Swift, Mihaiela and Tiley, Laurence S. and Lyall, Jonathan and Aguirre-Hernández, Jesús and Field, Hugh J. (2008) A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target. Journal of Antimicrobial Chemotherapy, 61 (5). pp. 1044-1047. ISSN 0305-7453

intentional mismatch primer PCR

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

latent infection

Biswas, Subhajit and Field, Hugh J. (2011) Helicase–primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus. In: Antiviral Drug Strategies. Methods and Principles in Medicinal Chemistry . Wiley-VCH Verlag GmbH & Co. KGaA, pp. 129-146. ISBN 9783527635955, 9783527326969

molecular phylogeny

Biswas, Subhajit and Sanyal, A. and Hemadri, D. and Tosh, C. and Gupta, S. K. and Mittal, M. and Mohapatra, J. K. and Sabarinath, G. P. and Kumar, R. Manoj and Bandyopadhyay, S. K. (2004) Sequence analysis of Vpg protein of Asia-1 field isolates of Foot and Mouth Disease Virus in India. Journal of Animal and Veterinary Advances, 3 (8). pp. 522-526. ISSN 1680-5593

mouse infection model

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

murine infection model

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

mutation

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

Biswas, Subhajit and Kleymann, Gerald and Swift, Mihaiela and Tiley, Laurence S. and Lyall, Jonathan and Aguirre-Hernández, Jesús and Field, Hugh J. (2008) A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target. Journal of Antimicrobial Chemotherapy, 61 (5). pp. 1044-1047. ISSN 0305-7453

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

nucleoside analogues

Biswas, Subhajit and Field, Hugh J. (2011) Helicase–primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus. In: Antiviral Drug Strategies. Methods and Principles in Medicinal Chemistry . Wiley-VCH Verlag GmbH & Co. KGaA, pp. 129-146. ISBN 9783527635955, 9783527326969

occult hepatitis B virus

Candotti , Daniel and Lin, C Kit and Belkhiri, Dalila and Sakuldamrongpanich, Tasanee and Biswas, Subhajit and Lin, Sujen and Teo, Diana and Ayob, Yasmin and Allain, Jean-Pierre (2012) Occult hepatitis B infection in blood donors from South East Asia: molecular characterisation and potential mechanisms of occurrence. Gut, 61 (12). pp. 1744-1753. ISSN 0017-5749

plaque reduction assay

Biswas, Subhajit and Field, Hugh J. (2011) Helicase–primase inhibitors: a new approach to combat herpes simplex virus and varicella zoster virus. In: Antiviral Drug Strategies. Methods and Principles in Medicinal Chemistry . Wiley-VCH Verlag GmbH & Co. KGaA, pp. 129-146. ISBN 9783527635955, 9783527326969

primase

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

protein secretion

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

ref03

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

Biswas, Subhajit and Kleymann, Gerald and Swift, Mihaiela and Tiley, Laurence S. and Lyall, Jonathan and Aguirre-Hernández, Jesús and Field, Hugh J. (2008) A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target. Journal of Antimicrobial Chemotherapy, 61 (5). pp. 1044-1047. ISSN 0305-7453

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Candotti , Daniel and Lin, C Kit and Belkhiri, Dalila and Sakuldamrongpanich, Tasanee and Biswas, Subhajit and Lin, Sujen and Teo, Diana and Ayob, Yasmin and Allain, Jean-Pierre (2012) Occult hepatitis B infection in blood donors from South East Asia: molecular characterisation and potential mechanisms of occurrence. Gut, 61 (12). pp. 1744-1753. ISSN 0017-5749

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

refdoi

Biswas, Subhajit and Kleymann, Gerald and Swift, Mihaiela and Tiley, Laurence S. and Lyall, Jonathan and Aguirre-Hernández, Jesús and Field, Hugh J. (2008) A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target. Journal of Antimicrobial Chemotherapy, 61 (5). pp. 1044-1047. ISSN 0305-7453

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Candotti , Daniel and Lin, C Kit and Belkhiri, Dalila and Sakuldamrongpanich, Tasanee and Biswas, Subhajit and Lin, Sujen and Teo, Diana and Ayob, Yasmin and Allain, Jean-Pierre (2012) Occult hepatitis B infection in blood donors from South East Asia: molecular characterisation and potential mechanisms of occurrence. Gut, 61 (12). pp. 1744-1753. ISSN 0017-5749

Matta, M. and Gopalakrishnan, R. and Graham, Ciaren and Tolani , B. and Khanna , A. and Yi, H. and Suo, Y. and Chaudhary, P. M. (2012) Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PloS One, 7 (5). e36601. ISSN 1932-6203

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Ruebsamen-Schaeff, Helga and Zimmermann, Holger and Field, Hugh J. (2010) Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant. Antiviral Research, 87 (1). pp. 67-73. ISSN 0166-3542

refdoibroken

Biswas, Subhajit and Candotti, Daniel and Allain, Jean-Pierre (2013) Specific amino acid substitutions in the S protein prevent its excretion in vitro and may contribute to occult hepatitis B virus infection. Journal of Virology . ISSN 0022-538X (In Press)

resistance

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

Sukla, Soumi and Biswas, Subhajit and Birkmann, Alexander and Lischka, Peter and Zimmermann, Holger and Field, Hugh J. (2010) Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor. Journal of Antimicrobial Chemotherapy, 65 (7). pp. 1347-52. ISSN 0305-7453

transfusion

Candotti , Daniel and Lin, C Kit and Belkhiri, Dalila and Sakuldamrongpanich, Tasanee and Biswas, Subhajit and Lin, Sujen and Teo, Diana and Ayob, Yasmin and Allain, Jean-Pierre (2012) Occult hepatitis B infection in blood donors from South East Asia: molecular characterisation and potential mechanisms of occurrence. Gut, 61 (12). pp. 1744-1753. ISSN 0017-5749

vFLIP

Graham, Ciaren and Matta, Hittu and Yang, Yanqiang and Yi, Han and Suo, Yulan and Tolani, Bhairavi and Chaudhary, Preet M. (2013) Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation. Journal of Virology . ISSN 0022-538x (In Press)

virus

Biswas, Subhajit and Field, Hugh J. (2008) Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations. Antiviral Chemistry & Chemotherapy, 19 (1). pp. 1-6. ISSN 0956-3202

Biswas, Subhajit and Núñez Miguel, Ricardo and Sukla, Soumi and Field, Hugh J. (2009) A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure. Journal of General Virology, 90 (8). pp. 1937-1942. ISSN 0022-1317

Biswas, Subhajit and Tiley, Laurence S. and Zimmermann, Holger and Birkmann, Alexander and Field, Hugh J. (2008) Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity. Antiviral Research, 80 (1). pp. 81-85. ISSN 0166-3542

Field, Hugh J. and Biswas, Subhajit (2011) Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus. Drug Resistance Updates, 14 (1). pp. 45-51. ISSN 1368-7646

Mohapatra, Jajati K. and Sanyal, Aniket and Hemadri, Divakar and Tosh, Chakradhar and Biswas, Subhajit and Knowles, Nick J. and Rasool, Thaha J. and Bandyopadhyay, Santanu K. and Pattnaik, Bramhadev (2008) Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades. Virus Research, 136 (1-2). pp. 16-29. ISSN 0168-1702