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Items where Subject is "C130 Cell Biology"

JACS Subject (180)
- C Biological Sciences (180)
  - C130 Cell Biology (180)

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2 amino 1 methyl 6 phenylimidazo4,5 bpyridine 2,5 di tert butylhydroquinone ?-MSH; Melanocortin receptors; Pigmentation ?-MSH; Melanocortin; Melanoma; Metastasis; NF-kappaB ?-melanocyte- stimulating hormone ?-melanocyte-stimulating hormone ?V?3 integrin ADIPOQ protein, human ADIPOR1 protein, human ADIPOR2 protein, human, animal AFM AFM-SCFS ALS4 ATM ATP Acetylcholine Acrylic acid; Allylamine; Keratinocytes; Melanocytes; Plasma polymerisation; Skin tissue engineering; Vitiligo Acute-phase proteins tobacco Adenosine Monophosphate Adenosine triphosphate Adherens Junction Adhesion Adipogenesis Adiponectin Adult Adult,Antioxidants,Antioxidants: analysis,Biological Markers,Biological Markers: blood,Case-Control Studies,Diabetes,Female,Fetal Blood,Fetal Blood: chemistry,Gestational,Gestational: blood,Humans,Lipid Peroxidation,Oxidative Stress,Pilot Projects,Pregnan Aggresomes Akt,MAPK,MCF-7 cells,PI3K,T-47-D cells,ZR-75-1 cells,akt,breast cancer cells,endocrine resistance,insulin,mTOR,mapk,mcf 7 cells,mtor,oestrogen,oestrogen deprived,oestrogen-deprived,pi3k,picropodophyllin,rapamycin,t 47 d cells,zr 75 1 cells Alpl Amphibian Amyloid Amyloidogenesis Androgen receptor,Cancer,Estrogen receptor,RNA polymerase I,Ribosomal RNA,Ribosome biogenesis Animal Animals Animals; Humans; Inflammation; Intracellular Space; Melanocortins; Pigmentation; Receptors Anionic antimicrobial peptides Anti-tumor Anticancer Antidepressants Apicomplexa Apoptosis Apoptosis,Internal ribosome entry site,Messenger RNA (mRNA) stability,Mitosis,Translation initiation,Upstream of N-ras (Unr) Aquaporin-1 Aqueous humor Article Ataxia Atomic force microscopy Axon growth BLM BRCA1 Bacteriocin Bag6 Base Sequence Base-excision repair Beta-cells Binding partners Biological Markers Biosensing Blood Glucose Brain transcriptome Breast Cancer Breast cancer Brightfield C90rf72 CCL2 protein, human CDC73 CFTR CHO Cells CHO cell line CO2 laser CPEO CaSR Caco2 cell Cadherin Calcimimetic Calcium Calcium ?-cell Islet Calcium Channel Blockers Calcium Channels Calcium-Calmodulin-Dependent Protein Kinases,Calcium-Calmodulin-Dependent Protein Kinases: anta,Cell Count,Cell Line,Cell Proliferation,Cell Proliferation: drug effects,Chromones,Chromones: pharmacology,Culture Media,Cultured,Dose-Response Relationship,Dr Carbachol Carboxyfluorescein Carcinogens Cas9 Caspase-3 Cell Communication Cell Culture Techniques Cell Line Cell Line, Tumor Cell Membrane Cell Nucleus Cell Separation Cell adhesion Cell biology Cell communication Cell cycle Cell longevity Cell morphology Cell surface morphology Cell surface roughness Cell viability Cell-free DNA Cell-to-cell communication Cells, Cultured Cellular processes Cellular uptake Chemokine CCL2 Chloroquine Cholesteryl esters Choroidal melanocytes Chronic kidney disease Colicin Connexin 43 Connexin-43 Connexins Cricetulus Cytochrome P-450 CYP1A2 Cytokines Cytoskeleton DJ-1 DM1 DNA (apurinic or apyrimidinic site) lyase DNA Adducts DNA Polymerase beta DNA Repair DNA adduct DNA catenation DNA damage DNA damage response DNA damages DNA directed DNA polymerase beta DNA intercalators DNA repair DNA replication Dendritic cells Dermis Detection rates Development Diabetes Diabetes Mellitus, Type 2 Diabetic nephropathy Dose-Response Relationship, Drug Double-strand break resection Dye uptake EB1 ECM proteins ELISA EME1 Elasticity Elov13 protein Embryonic Stem Cells Enc1 Endothelium, Vascular Epithelial cells Evolution, Molecular Excimer laser Exosomes Expert knowledge Extracellular matrix protein Extracellular signal-regulated kinase FANCD2 FGF2 FGF2 diffusion FTIR Fast atom bombardment mass spectrometry Female Fibrillarin Fibrosis Flow cytometry Fluorescence Fluorometry Fluorophores Forskolin Fracture Fracture healing Functional genomics Fura-2 GASC Gap junctions Gastrins Gene Expression Data Gene coexpression network Gene expression Gene regulation Genetics Glioma Glyburide Granulosa Cells Ground truth Growth Factor HEK293 Cells HEK293 cell line HMOX1 protein, human HSP90 Haematoma Haematopoietic Stems Cell Heamatopiotic stem cells Helicase Heme Oxygenase-1 Hemichannels Heparan Sulphate Hepatocytes Heterogeneity; High variability High-throughput Histone modification Holliday junctions Homologous recombination repair Hormonal receptors Hsp90 Hsp90; MAP kinase; Slt2(Mpk1); Transcription activation; Yeast. Human Human Umbilical Cord Blood Human Umbilical cord Blood Human airway smooth muscle cells Human brain development Human umbilical cord blood Humans Hybrid image IL33 protein, human IL6 protein, human Identification (control systems) Image processing Image processing algorithm Imaging systems Imidazoles Immunohistochemistry Indentation Infectious disease Infectious diseases Inflammation Innervation Insulin Insulin sensitivity Insulin-Secreting Cells Integrin Integrins Intercellular Adhesion Molecule-1 Interleukin-23 Interleukin-6 Interleukins Intracellular Membranes Invasion Invasion models Islets of Langerhans Isothiocyanates JCNotOpen JCOpen Kidney Kinetochores LIG3 Labelling Liquid crystals Low contrast MEK/ERK MUC1 MUC12 MUC3 MUC6 mucin MUS81 Malaria Male Mass Spectrometry Matrix metalloproteinases Mechanism of action Melano cortin Melanocortin Melanocortin; Signal Transduction Melanoma Membrane Transport Proteins Membranolysis Mesenchymal stem cell Mesenchymal stem cells Metabolic pathway Metabolism Metformin Mice Microcirculation Microhomology-mediated end-joining Microscope images Microscopes Microtubules Mislocalised proteins Mitochondrial complexes Mitochondrial dysfunction Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Model Molecular Biology Molecular Sequence Data Multi-photon absorption Multiphoton processes Muscarinic acetylcholine receptor Mutation Myosin VI Myosins NAC NADPH Dehydrogenase NADPH Oxidase NANOG NBS1 NDP52 NEXAFS; Plasma copolymer; Protonated amine; XPS NF-kappaB NLRP3 NS1 Nephropathy Neural maintenance Neurology Neuroscience Nitrendipine NotOAChecked Novel Method Novel method Nuclear export Nucleic acids, Cells Nucleolus O-glycosylation OCT3-4 Obesity Oestradiol Osmolar Concentration Osmosis Osteoblast cells Oxidation-Reduction Oxidative DNA damage Oxidative stress P2X7 PABP PARP inhibition (PARPi) PET PI3K PICH POLG Panc1 cell Pancreas Pancreatic Neoplasms Pancreatic beta cells Pancreatic islets Parafibromin Parasitology Parkinson's disease Peptide 5 Peptide5 Pharmacodynamic Phosphoproteins Physiology Polymerase Chain Reaction Potassium Channel Blockers Potassium Channels Prostaglandins Proteasomes Protein Transport Protein biogenesis Protein degradation Protein synthesis Protein targeting Protein translocation Proteins Proteomics Protoporphyrins Protozoa Pyloric Antrum RAD51 RIG-I RNA RNA Polymerase II RNA polymerase I RNA polymerase II RNA, Messenger RNA, Small Interfering RNAseq RPE cells Raman Spectroscopy Rats Reactive Oxygen Species Reactive oxygen species Receptor Receptors, Adiponectin Receptors, Purinergic Recombinant proteins Red cell Redox chemistry Reflexion coefficient Regulation Renal fibrosis Representative sample Reverse Transcriptase Polymerase Chain Reaction Ribonuclease Ribosome Robotic systems Robust identification Robust technique SCAN1,TDP,UCHL3,aging,cancer,heart failure,myocardial infarction,neurodegeneration,rhabdosarcoma,topoisomerase SEA SMN SNAP-tag technology SOX2 STAT5 Senataxin Sgt1 She4 Signal recognition particle Signal Transduction Single molecule Singlet Oxygen Skp1 Smoking Sperm Motility Spermatozoa Sphingolipids Stem Cells Stem cell, Artificial intelligence Stemness” genes Stiffness Structure Structure-Activity Relationship Support, Non-U.S. Gov't Sympathetic neuron TGF-beta1 TGF? TNF Receptor-Associated Factor 4 TPR TRIM25 Tamoxifen Tel/PDGFRbeta Temperature stress Terbutaline Terpenes Thin layered chromatography Thiocyanates Thioridazine Tibial fracture Tibial fracture Time Factors Tonabersat Topoisomerase II Toxoplasmosis Transcription, Genetic Transcriptional signature Tropical Neglected diseases Tumor Cells, Cultured Tumor Necrosis Factor Receptor-Associated Peptides and Proteins Tumor Necrosis Factor-alpha Tumor Necrosis Factor-alpha, Tiron UCS Protein UCS protein UFBs UNC45 Ubiquitin ligase Ubiquitylation Unconventional Unr Vaccine Vero cells Vitreous humor Vivax malaria Water channels Western blotting X box binding protein 1 Yeast a-melanocyte stimulating hormone acetylcholine actin adenosine 5' o (3 thiotriphosphate) adenosine 5'-O-(3-thiotriphosphate) adenosine diphosphate adenosine phosphate adenosine triphosphate adipocyte adiponectin adiponectin receptor adipose tissue adult airway airway epithelium alpha 2 adrenergic receptor blocking agent angiogenesis animal animal experiment animal model animal tissue archaeon article asthma atropine bacterium binding and related phenomena bio-sensing bioactivity bioactivity of NiTi biochemistry biosynthesis blood viscosity bmjanomaly bmjconvert bmjlink bmjtype body fluid body weight bone morphogenetic protein breast cancer breast cancer stem cell brown adipose tissue cRGD cRGD-peptide cadherin caffeine calcimimetics calcium calcium cell level calcium channel calcium homeostasis calcium ion calcium ions calcium mobilization calcium sensing receptor calcium transport cancer cancer inhibition carbon 14 carboxypeptidase carboxypeptidase x1 carcinogen cell activity cell adhesion cell communication cell coupling cell culture cell differentiation cell isolation cell line cell membrane cell membrane depolarization cell proliferation cell protection cell separation cell strain HepG2 cell stress cell substrates cell survival cell-cell coupling cell-substrate cellular distribution cellular senescence channel gating chemical proteomics chemistry chloride channels chromatin remodeling chromosome instability chromosome missegregation chronic kidney disease click chemistry co-expression networks cold exposure collagen colorectal cancer colorectal carcinoma common fragile site concentration response conference paper confocal microscopy connexin connexins controlled study corpus luteum correlation crypsis cryptic female choice culture technique cyclophilin cystic fibrosis cystic fibrosis transmembrane conductance regulator cytochrome P450 1A2 cytokine cytokine production cytokines cytology cytoplasm cytoskeleton cytosol cytotoxicity danegaptide dermal fibroblasts detoxification developmental stage diabetes diabetic nephropathy diabetic retinopathy dietary intake dietary-crocin differentiation dimerisation double-strand breaks drug derivative drug effect drug effects drug potentiation efaroxan egg electrophysiology embryo embryo development endoplasmic reticulum stress endosomal compartment endothelium cell environmental temperature enzyme activity enzyme assay enzyme induction enzyme inhibition epididymis fat epithelium eukaryote eukaryotic flagellum evolutionary biology exposure extracellular calcium extracellular matrix female fertilization fertilization (reproduction) fibroblast growth factor fibroblast growth factor 1 fibroblasts fibrosis filamentous fungi flagellum flavonoid fluorometry food intake fura 2 gap-junctions gastrin release gastrin, article gene expression gene expression regulation gene sequence gene transcription genetics genome maintenance genome stability genome-wide siRNA screen genomic instability glucose glucose blood level glucose homeostasis glucose tolerance glucose transport glucose transporter 1 glucose transporter 4 glucuronosyltransferase glutathione transferase glycemic control glycerol 3 phosphate dehydrogenase gm1 granulosa cell hPTECs heme oxygenase 1 hemi-channels hemichannel hemichannels histology homologous recombination hormone determination human human cell hydrolysis hyperglycemia hypothesis idazoxan imaging imidazoline immune response immune system immunoblotting immunoepidemiology immunogenicity immunoglobulin enhancer binding protein immunology immunoprecipitation immunosuppression in vitro study in vitro test in vivo test inflamasome inflammasome inflammation influenza A virus insulin insulin release insulin resistance insulin sensitivity insulin synthesis intercellular adhesion molecule 1 interleukin 22 interleukin 23 interleukin 24 interleukin 33 interleukin 6 interleukin derivative interleukin-22 interleukin-24 interleukin-33, mouse, animal cell interscapular brown adipose tissue interstitial collagenase intracellular membrane invasion isothiocyanic acid isotope labeling karyopherin b2 keratinocyte kidney kidney disease kinetics laser linear system lipid composition lipid raft lipid storage liver cell lymphocyte transformation assay male mass spectrometer mechanical measurements mechanobiology melanin membrane biophysics membrane dynamics mesenchymal stem cell (MSC) mesnchymal stem cell mesnchymal stem cells messenger RNA metabolism metastasis microarray microfluorometry microplate reader assay mineralization mitochondrial biogenesis mitogen activated protein kinase mitogen activated protein kinase 1 mitogen activated protein kinase 3 mixed lymphocyte reaction molecular cloning molecular evolution molecular motors monocyte chemotactic protein 1 monomerisation mouse mtDNA replication mucin O-glycosylation mucus mutation myosin VI myosins nanomedicine nerve cell culture nerve cell differentiation nerve fiber growth nervous system nervous system development non insulin dependent diabetes mellitus nonhuman nuclear transfer nuclear transport nucleotide sequence nylon 6 6 nylon 66 obesity orlistat oscillation osmolarity osteoblast osteoblast cells oxidative stress pancreas pancreas cell pancreas islet pancreas islet beta cell pancreas tumor peptide pericellular matrix peroxisome proliferator activated receptor gamma peroxisome proliferator activated receptor gamma coactivator 1alpha phentolamine phorbol ester phosphorylation physics physiological process physiology physiology, Adenosine Triphosphate physiology, Adipocytes phytochemistry plasma glucose concentration platelet derived growth factor platelet derived growth factor BB poliovirus polyacrylamide gel electrophoresis polydeoxyribonucleotide synthase polymyxin B polyphosphoinositides postnatal development potassium channel, animal cell potassium channel, binding site potassium chloride, article prion priority journal priority journal, Adenosine Diphosphate proadipocyte proinsulin protein protein determination protein expression protein kinase C protein localization protein protein interaction protein secretion proteolytic cleavage protoporphyrin protoporphyrin cobalt purine receptor purine receptor, article purines quercetin rat rat, Adenosine Diphosphate reactive oxygen metabolite real time polymerase chain reaction reduced nicotinamide adenine dinucleotide phosphate oxidase regenerative medicine regulatory mechanism repolarization, Adenosine Diphosphate reverse transcription polymerase chain reaction ribosomal DNA ribosomal RNA ribosome ribosome RNA ribosome biogenesis ryanodine secretion (process), Mus, Animals senescence sequence homology signal transduction signal transduction, Acetylcholine signal transduction, Animals single molecule small gold nanoparticles somatostatin somatostatin release somatostatin release, Acetylcholine somatostatin, calcium cell level spatial organisation spectrofluorometry sperm competition sperm competition, adaptation sperm length components sperm length components, Adaptation, Physiological spermatozoon spermatozoon motility, Cryptic female choice statistical significance stomach antrum, Adrenergic beta-Agonists subcutaneous drug administration subcutaneous fat sulforaphane, article sulphation superior cervical ganglion swimming sympathetic nerve cell targeted drug delivery temperature dependence temperature stress terpene thapsigargin tissue engineering transcription transcription factor transcription initiation transcription regulation transformation tubular epithelia tubulointerstitial inflammation tumor necrosis factor alpha tumor necrosis factor alpha, adipocyte tumor necrosis factor receptor tumor necrosis factor receptor 1 tumor necrosis factor receptor 2, animal cell tumor necrosis factor receptor associated factor 4 tumorigenicity tumour suppressor ultra ultra-fine DNA bridges ultra-small gold nanoparticles unclassified drug unclassified drug, adipogenesis unclassified drug, article uncoupling protein 1, adipocyte uridine triphosphate variance, Anticarcinogenic Agents velocity verapamil, article virus viscosity visfatin wettability white adipose tissue wild type, Animals xenograft yeast Î±VÎ²3 integrin

Number of items at this level: 1297.

2 amino 1 methyl 6 phenylimidazo4,5 bpyridine

Bacon, James R., Williamson, Gary, Garner, R. Colin, Lappin, Graham, Langouet, Sophie and Bao, Yongping (2003) Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis, 24 (12). pp. 1903-1911. ISSN 0143-3334

2,5 di tert butylhydroquinone

Squires, Paul E., Amiranoff, Brigitte and Dunne, Mark J. (1994) Intracellular Ca2+ signals in human-derived pancreatic somatostatin-secreting cells (QGP-1N). Pflugers Archiv European Journal of Physiology, 428 (3-4). pp. 275-282. ISSN 0031-6768

Squires, Paul E., James, R. F. L., London, N. J. M. and Dunne, M. J. (1994) ATP-induced intracellular Ca2+ signals in isolated human insulin-secreting cells. Pflugers Archiv European Journal of Physiology, 427 (1-2). pp. 181-183. ISSN 0031-6768

?-MSH; Melanocortin receptors; Pigmentation

Eves, P. C., MacNeil, S. and Haycock, J. W. (2006) α-Melanocyte stimulating hormone, inflammation and human melanoma. Peptides, 27 (2). pp. 444-452. ISSN 0196-9781

?-MSH; Melanocortin; Melanoma; Metastasis; NF-kappaB

Eves, Paula, Haycock, J. W., Layton, C., Wagner, M., Kemp, H., Szabo, M., Morandini, R., Ghanem, G., Garcia-Boron, J. C., Jiménez-Cervantes, C. and MacNeil, S. (2003) Anti-inflammatory and anti-invasive effects of α-melanocyte- stimulating hormone in human melanoma cells. British Journal of Cancer, 89 (10). pp. 2004-2015. ISSN 0007-0920

?-melanocyte- stimulating hormone

?-melanocyte-stimulating hormone

Canton, Irene, Eves, Paula, Szabo, Marika, Vidal-Vanaclocha, Fernando, Sisley, Karen, Rennie, Ian G., Haycock, John W. and MacNeil, Sheila (2003) Tumor necrosis factor α increases and α-melanocyte-stimulating hormone reduces uveal melanoma invasion through fibronectin. Journal of Investigative Dermatology, 121 (3). pp. 557-563. ISSN 0022-202X

?V?3 integrin

Perrins, Richard D., McCarthy, Lee-Anne, Robinson, Angela, Spry, Kelly L., Cognet, Valentin, Ferreira, Avelino, Porter, John, García, Cristina Espinosa, Rodriguez, Miguel Ángel, Lopez, Diana, Perera, Ibon, Conlon, Kelly, Barrientos, Africa, Coulter, Tom, Pace, Alessandro, Hale, Sarah J. M., Ferrari, Enrico and Bachrati, Csanad Z. (2022) Targeting Ultrasmall Gold Nanoparticles with cRGD Peptide Increases the Uptake and Efficacy of Cytotoxic Payload. Nanomaterials, 12 (22). p. 4013. ISSN 2079-4991

ADIPOQ protein, human

Yang, Mengliu, Kimura, Masaki, Ng, Choaping, He, Jingjing, Keshvari, Sahar, Rose, Felicity J., Barclay, Johanna L. and Whitehead, Jonathan P. (2015) Induction of heme-oxygenase-1 (HO-1) does not enhance adiponectin production in human adipocytes: evidence against a direct HO-1 - Adiponectin axis. Molecular and Cellular Endocrinology, 413 . pp. 209-216. ISSN 0303-7207

ADIPOR1 protein, human

Keshvari, Sahar and Whitehead, Jonathan P. (2015) Characterisation of the adiponectin receptors: differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks. Molecular and Cellular Endocrinology, 409 . pp. 121-129. ISSN 0303-7207

ADIPOR2 protein, human, animal

AFM

Caponnetto, Federica, Manini, Ivana, Skrap, Miran, Palmai-Pallag, Timea, Di Loreto, Carla, Beltrami, Antonio Paolo, Cesselli, Daniela and Ferrari, Enrico (2017) Size-dependent cellular uptake of exosomes. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (3). pp. 1011-1020. ISSN 1549-9634

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

Lherbette, Michael, Dos Santos, Ália, Hari-Gupta, Yukti, Fili, Natalia, Toseland, Christopher P. and Schaap, Iwan A. T. (2017) Atomic Force Microscopy micro-rheology reveals large structural inhomogeneities in single cell-nuclei. Scientific Reports, 7 (1). p. 8116. ISSN 2045-2322

Siamantouras, Eleftherios, Hills, Claire E., Liu, Kuo-Kang and Squires, Paul E. (2020) Chapter 14: Examining cell-cell interactions in the kidney using AFM single-cell force spectroscopy. In: Diabetic Nephropathy Methods & Protocols. Methods in Molecular Biology Series, 2067 . Springer Science+Business Media, LLC, part of Springer Nature. ISBN 978-1-4939-9840-1

Siamantouras, Eleftherios, Liu, K-K, Hills, Claire and Squires, Paul (2015) Investigating changes in cell-to-cell adhesion during early proximal tubular injury induced by Transforming Growth Factor-beta in diabetic nephropathy. In: Diabetes UK AGM, 11/03/2015 - 13/03/2015, Liverpool.

Siamantouras, Eleftherios, Hills, Claire, Liu, Kuo-Kang and Squires, Paul (2020) Examining Cell-Cell Interactions in the Kidney Using AFM Single-Cell Force Spectroscopy. In: Diabetic Nephropathy. Methods in Molecular Biology, 2067 . Humana Press, Humana, New York, NY, pp. 189-201. ISBN 978-1-4939-9840-1, 978-1-4939-9841-8

Siamantouras, Eleftherios, Liu, K-K, Hills, Claire and Squires, Paul (2014) Quantitative investigation of calcium-sensing receptor activation on beta-cell adhesion and mechanics. In: Diabetes UK AGM, 05/03/2014 - 07/03/2014, Liverpool.

Siamantouras, Eleftherios, Liu, Lidong, Squires, Paul and Hills, Claire (2018) Understanding the biophysics of diabetic nephropathy: modelling TGFβ1 evoked changes in viscoelasticity of epithelial cells of the proximal tubule. In: Diabetes UK AGM, 14/03/2018 - 16/03/2018, London.

Soon, C. F., Omar, W. I. W., Berends, R. F., Nayan, N., Basri, H., Tee, K. S., Youseffi, M., Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

AFM-SCFS

Siamantouras, Eleftherios, Hills, Claire E., Younis, Mustafa Y. G., Squires, Paul and Liu, Kuo-Kang (2014) Quantitative investigation of calcimimetic R568 on beta-cell adhesion and mechanics using AFM single-cell force spectroscopy. FEBS Letters, 588 (7). pp. 1178-1183. ISSN 0014-5793

Siamantouras, Eleftherios, Price, Gareth, Potter, Joe, Hills, Claire and Squires, Paul (2019) Purinergic receptor (P2X7) activation reduces cell–cell adhesion between tubular epithelial cells of the proximal kidney. Nanomedicine: Nanotechnology, Biology and Medicine, 22 . ISSN 1549-9634

Squires, Paul, Siamantouras, Eleftherios, Potter, Joe, Price, Gareth and Hills, Claire (2019) ATP reduces functional cell-to-cell tethering between renal tubular epithelial cells. In: Physiology 2019 (The Physiological Society), 08/07/19-to-10/07/19, Aberdeen.

ALS4

Bennett, Craig L., Sopher, Bryce L. and La Spada, Albert R. (2020) Tight expression regulation of senataxin, linked to motor neuron disease and ataxia, is required to avert cell-cycle block and nucleolus disassembly. Heliyon, 6 (6). e04165. ISSN 2405-8440

ATM

Walker, Callum, Herranz-Martin, Saul, Karyka, Evangelia, Liao, Chunyan, Lewis, Katherine, Elsayed, Waheba, Lukashchuk, Vera, Chiang, Shih-Chieh Chieh, Ray, Swagat, Mulcahy, Padraig J., Jurga, Mateusz, Tsagakis, Ioannis, Iannitti, Tommaso, Chandran, Jayanth, Coldicott, Ian, De Vos, Kurt J., Hassan, Mohamed K., Higginbottom, Adrian, Shaw, Pamela J., Hautbergue, Guillaume M., Azzouz, Mimoun and El-Khamisy, Sherif F. (2017) C9orf72 expansion disrupts ATM-mediated chromosomal break repair. Nature Neuroscience, 20 (9). pp. 1225-1235. ISSN 1097-6256

ATP

Hills, C. E., Price, G. W., Wall, M. J., Kauffman, T. J., Tang, S. C., Yiu, W. H. and Squires, Paul (2018) Transforming Growth Factor Beta 1 drives a switch in connexin mediated cell-to-cell communication in tubular cells of the diabetic kidney. Cellular Physiology and Biochemistry, 45 (6). pp. 2369-2388. ISSN 1015-8987

Hills, Claire, Price, Gareth and Squires, Paul (2017) A role for ATP in tubular fibrosis in the diabetic kidney. In: Diabetes AGM, 08/03/2017 - 10/03/2017, Manchester.

Potter, Joe, Price, Gareth, Cliff, Chelsy L, Green, Colin R, Squires, Paul and Hills, Claire (2021) Collagen I Modifies Connexin‐43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1‐Evoked Renal Tubular Epithelial Cells. International Journal of Molecular Sciences, 22 (7). p. 3644. ISSN 1422-0067

Price, Gareth, Liu, K-K, Squires, Paul and Hills, Claire (2014) Glucose-evoked transforming growth factor reduces connexin and purinergic signalling in proximal tubule-derived epithelial cells. In: Diabetes UK AGM, 05/03/2014 - 07/03/2014, Liverpool.

Price, Gareth, Potter, Joe, Squires, Paul and Hills, Claire (2018) A role for ATP in renal fibrosis as a downstream mediator of TGF-β1-evoked changes in hemichannel activity. In: Diabetes UK AGM, 14/03/2018 - 16/03/2018, London.

Price, Gareth, Potter, Joe, Williams, Bethany M, Cliff, Chelsy L, Squires, Paul and Hills, Claire (2020) A role for connexin-43 hemichannel-mediated adenosine triphosphate triphosphate (ATP) release in inﬂammation of the diabetic proximal tubule. In: Diabetes UK AGM, Online.

Price, Gareth, Squires, Paul and Hills, Claire (2015) Transforming Growth Factor Beta 1 alters purinergic signalling and increases ATP release from epithelial cells derived from the human proximal tubule. In: Diabetes UK AGM, 11/03/2015 - 13/03/2015, Liverpool.

Squires, Paul, Price, Gareth and Hills, Claire (2016) Connexins, hemi-channels and ATP release in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

Squires, Paul, Price, Gareth, Mouritzen, Ulrik, Potter, Joe, Williams, Bethany and Hills, Claire (2021) Danegaptide Prevents TGFβ1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney. International Journal of Molecular Sciences, 22 (2809). ISSN 1422-0067

Acetylcholine

Selway, J. L., Moore, C. E., Mistry, R., Challiss, R. A. J. and Herbert, T. P. (2012) Molecular mechanisms of muscarinic acetylcholine receptor-stimulated increase in cytosolic free Ca2+ concentration and ERK1/2 activation in the MIN6 pancreatic b-cell line. Acta Diabetologica, 49 (4). pp. 277-289. ISSN 0940-5429

Acrylic acid; Allylamine; Keratinocytes; Melanocytes; Plasma polymerisation; Skin tissue engineering; Vitiligo

Eves, P., Beck, A. J., Shard, A. G. and MacNeil, S. (2005) A chemically defined surface for the co-culture of melanocytes and keratinocytes. Biomaterials, 26 (34). pp. 7068-7081. ISSN 0142-9612

Acute-phase proteins tobacco

Sloan, Andrew, Hussain, Issam, Maqsood, Mohmeed, Eremin, Oleg and El-Sheemy, Mohamed (2010) The effects of smoking on fracture healing. The Surgeon, 8 (2). pp. 111-116. ISSN 1479-666X

Adenosine Monophosphate

Adenosine triphosphate

Price, Gareth, Potter, Joe, Williams, Bethany, Cliff, Chelsy, Wall, Mark, Hills, Claire and Squires, Paul (2020) Examining Local Cell-to-Cell Signalling in the Kidney Using ATP Biosensing. In: Methods in Molecular Biology. Springer, New York. ISBN UNSPECIFIED

Adherens Junction

Adhesion

Adipogenesis

He, Jingjing, Chen, Daniel L., Samocha-Bonet, Dorit, Gillinder, Kevin R., Barclay, Johanna L., Magor, Graham W., Perkins, Andrew C., Greenfield, Jerry R., Yang, Gongshe and Whitehead, Jon (2016) Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4) – a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity. Growth Factors, 34 (5-6). pp. 210-216. ISSN 0897-7194

Adiponectin

Keshvari, Sahar, Henstridge, Darren, Ng, Choaping, Febbraio, Mark and Whitehead, Jon (2017) Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects. Scientific Reports, 7 (41792). ISSN 2045-2322

Adult

Ray, J. M., Squires, Paul, Meloche, R. M., Nelson, D. W., Snutch, T. P. and Buchan, A. M. J. (1997) L-type calcium channels regulate gastrin release from human antral G cells. American Journal of Physiology - Gastrointestinal and Liver Physiology, 273 (2). G281-G288. ISSN 0193-1857

Adult,Antioxidants,Antioxidants: analysis,Biological Markers,Biological Markers: blood,Case-Control Studies,Diabetes,Female,Fetal Blood,Fetal Blood: chemistry,Gestational,Gestational: blood,Humans,Lipid Peroxidation,Oxidative Stress,Pilot Projects,Pregnan

Dey, Prasenjit, Gupta, Preeti, Acharya, Nimish Kumar, Rao, Srinivasa Nageswara, Ray, Swagat, Chakrabarty, Sanjiban, Ramprasad, Sharanya, Kurian, Tina Ann, Mawroh, Anatoli, Kundu, Aishwarya, Bhaktha, Geetha, Joseph, Christy Philip, Kumar, Pratap, Rai, Lavanya and Rao, Anjali (2008) Antioxidants and lipid peroxidation in gestational diabetes--a preliminary study. Indian journal of physiology and pharmacology, 52 (2). pp. 149-56. ISSN 0019-5499

Aggresomes

Riess, Nicholas, Milward, Kelly, Lee, Tracy, Adams, Matthew, Askham, Jon M and Morrison, Ewan E (2005) Trapping of normal EB1 ligands in aggresomes formed by an EB1 deletion mutant. BMC Cell Biology, 6 (1). p. 17. ISSN 1471-2121

Akt,MAPK,MCF-7 cells,PI3K,T-47-D cells,ZR-75-1 cells,akt,breast cancer cells,endocrine resistance,insulin,mTOR,mapk,mcf 7 cells,mtor,oestrogen,oestrogen deprived,oestrogen-deprived,pi3k,picropodophyllin,rapamycin,t 47 d cells,zr 75 1 cells

Ray, Swagat and Darbre, Philippa D. (2011) Crosstalk with insulin and dependence on PI3K/Akt/mTOR rather than MAPK pathways in upregulation of basal growth following long-term oestrogen deprivation in three human breast cancer cell lines. Hormone Molecular Biology and Clinical Investigation, 5 (2). pp. 53-65. ISSN 1868-1883

Alpl

Worton, Leah E., Shi, Yan-Chuan, Smith, Elisabeth J., Barry, Simon C., Gonda, Thomas J., Whitehead, Jon and Gardiner, Edith M. (2017) Ectodermal-neural cortex 1 isoforms have contrasting effects on MC3T3-E1 osteoblast mineralization and gene expression. Journal of Cellular Biochemistry, 118 (8). pp. 2141-2150. ISSN 0730-2312

Amphibian

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Amyloid

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Amyloidogenesis

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Androgen receptor,Cancer,Estrogen receptor,RNA polymerase I,Ribosomal RNA,Ribosome biogenesis

Ray, Swagat, Johnston, Rebecca, Campbell, David C, Nugent, Shannen, McDade, Simon S, Waugh, David and Panov, Konstantin I (2013) Androgens and estrogens stimulate ribosome biogenesis in prostate and breast cancer cells in receptor dependent manner. Gene, 526 (1). pp. 46-53. ISSN 1879-0038

Animal

Dunne, Mark J., Harding, Elizabeth A., Jaggar, Jonathan H., Squires, Paul E., Liang, Rixin, Kane, Charlotte, James, Roger F. L. and London, Nicholas J. M. (1995) Potassium channels, imidazolines, and insulin-secreting cells. Annals of the New York Academy of Sciences, 763 . pp. 243-261. ISSN 0077-8923

Harding, E. A., Jaggar, J. H., Squires, Paul E. and Dunne, M. J. (1994) Polymyxin B has multiple blocking actions on the ATP-sensitive potassium channel in insulin-secreting cells. Pflugers Archiv European Journal of Physiology, 426 (1-2). pp. 31-39. ISSN 0031-6768

Animals

Simpson, Julia L., Humphries, Stuart, Evans, Jonathan P., Simmons, Leigh W. and Fitzpatrick, John L. (2014) Relationships between sperm length and speed differ among three internally and three externally fertilizing species. Evolution, 68 (1). pp. 92-104. ISSN 0014-3820

Animals; Humans; Inflammation; Intracellular Space; Melanocortins; Pigmentation; Receptors

Eves, Paula and Haycock, J. W. (2010) Melanocortin signalling mechanisms. In: Melanocortins: multiple actions and therapeutic potential. Advances in Experimental Medicine and Biology, 681 . Elsevier, pp. 19-28. ISBN 9781441963536, 9781441963543

Anionic antimicrobial peptides

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Anti-tumor

Lancaster, Lorna, Wintermeyer, Wolfgang and Rodnina, Marina (2007) Colicins and their potential in cancer treatment. Blood, Cells, Molecules and Diseases, 38 (1). pp. 15-18. ISSN 1079-9796

Anticancer

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Antidepressants

Adbel-Razaq, W., Kendall, D. A. and Bates, T. E. (2011) The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria. Neurochemical Research, 36 (2). pp. 327-338. ISSN 0364-3190

Apicomplexa

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Apoptosis

Apoptosis,Internal ribosome entry site,Messenger RNA (mRNA) stability,Mitosis,Translation initiation,Upstream of N-ras (Unr)

Ray, Swagat, Catnaigh, Pol and Anderson, Emma C. (2015) Post-transcriptional regulation of gene expression by Unr. Biochemical Society Transactions, 43 (3). ISSN 0300-5127

Aquaporin-1

Curry, M. R., Shacher-Hill, B. and Hill, A. E. (2001) Single water channels of aquaporin-1 do not obey the Kedem-Katchalsky equations. Journal of Membrane Biology, 181 (2). pp. 115-123. ISSN 0022-2631

Aqueous humor

Article

Hasnain, Sumaira Z., Borg, Danielle J., Harcourt, Brooke E., Tong, Hui, Sheng, Yonhua H., Ng, Choa ping, Das, Indrajit, Wang, Ran, Chen, Alice C.-H., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathan P., Forbes, Josephine M., Prins, Johannes B. and McGuckin, Michael A. (2014) Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nature Medicine, 20 (12). pp. 1417-1426. ISSN 1078-8956

Jia, R., Luo, X.-Q., Lin, C.-X., Qiao, H., Wang, N., Yao, T., Barclay, J. L., Whitehead, J. P., Luo, X. and Yan, J.-Q. (2016) Characterization of cold-induced remodelling reveals depot-specific differences across and within brown and white adipose tissues in mice. Acta Physiologica, 217 (4). pp. 311-324. ISSN 1748-1708

Kim, Yu-Hee, Barclay, Johanna, He, Jingjing, Luo, Xiao, O'Neill, Hayley, Keshvari, Sahar, Webster, Julie, Ng, Choaping, Hutley, Louise, Prins, John and Whitehead, Jon (2016) Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis. FASEB Journal, 30 (7). pp. 2528-2540. ISSN 0892-6638

Nolan, Aoife M., Collins, Louise M., Wyatt, Sean L., Gutierrez, Humberto and O'Keeffe, Gerard W. (2014) The neurite growth inhibitory effects of soluble TNFα on developing sympathetic neurons are dependent on developmental age. Differentiation, 88 (4-5). pp. 124-130. ISSN 0301-4681

Ataxia

Atomic force microscopy

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

Axon growth

O’Keeffe, Gerard W., Gutierrez, Humberto, Howard, Laura, Laurie, Christopher W., Osorio, Catarina, Gavaldà, Núria, Wyatt, Sean L. and Davies, Alun M. (2016) Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation. Neural Development, 11 (1). ISSN 1749-8104

BLM

Chan, Kok Lung, Palmai-Pallag, Timea, Ying, Songmin and Hickson, Ian D. (2009) Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nature Cell Biology, 11 (6). pp. 753-760. ISSN 1465-7392

BRCA1

Johnston, Rebecca, D'Costa, Zenobia, Ray, Swagat, Gorski, Julia, Paul Harkin, D., Mullan, Paul and Panov, Konstantin I. (2016) The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription. Oncotarget, 7 (42). pp. 68097-68110. ISSN 1949-2553

Bacteriocin

Lancaster, Lorna, Wintermeyer, Wolfgang and Rodnina, Marina (2007) Colicins and their potential in cancer treatment. Blood, Cells, Molecules and Diseases, 38 (1). pp. 15-18. ISSN 1079-9796

Bag6

Leznicki, P., Korac-Prlic, J., Kliza, K., Husnjak, K., Nyathi, Y., Dikic, I. and High, S. (2015) Binding of SGTA to Rpn13 selectively modulates protein quality control. Journal of Cell Science, 128 (17). pp. 3187-3196. ISSN 0021-9533

Base Sequence

Base-excision repair

Roy, Abhipsa, Kandettu, Amoolya, Ray, Swagat and Chakrabarty, Sanjiban (2022) Mitochondrial DNA replication and repair defects: Clinical phenotypes and therapeutic interventions. Biochimica et Biophysica Acta (BBA) - Bioenergetics . ISSN 0005-2728

Beta-cells

Herbert, Terence and Wardman, Rhys (2019) 'The global identification of glucose-regulated RNA binding proteins (RBPs) in pancreatic β-cells reveals a link between insulin secretion and gene expression.'. In: Translation UK 2019, 3-5 July 2019, Strathclyde Business School, Glasgow.

Binding partners

Fili, Natalia, Hari-Gupta, Yukti, Aston, Bjork, Dos Santos, Ália, Gough, Rosemarie E., Alamad, Bana, Wang, Lin, Martin-Fernandez, Marisa L. and Toseland, Christopher P. (2020) Competition between two high- and low-affinity protein-binding sites in myosin VI controls its cellular function. The Journal of Biological Chemistry, 295 (2). pp. 337-347. ISSN 0021-9258

Biological Markers

Biosensing

Blood Glucose

Brain transcriptome

Monzón-Sandoval, Jimena, Castillo-Morales, Atahualpa, Urrutia, Araxi O. and Gutierrez, Humberto (2016) Modular reorganization of the global network of gene regulatory interactions during perinatal human brain development. BMC developmental biology, 16 . p. 13. ISSN 1471-213X

Breast Cancer

Lord, Simon R., Cheng, Wei-Chen, Liu, Dan, Gaude, Edoardo, Haider, Syed, Metcalf, Tom, Patel, Neel, Teoh, Eugene J., Gleeson, Fergus, Bradley, Kevin, Wigfield, Simon, Zois, Christos, McGowan, Daniel R., Ah-See, Mei-Lin, Thompson, Alastair M., Sharma, Anand, Bidaut, Luc, Pollak, Michael, Roy, Pankaj G., Karpe, Fredrik, James, Tim, English, Ruth, Adams, Rosie F., Campo, Leticia, Ayers, Lisa, Snell, Cameron, Roxanis, Ioannis, Frezza, Christian, Fenwick, John D., Buffa, Francesca M. and Harris, Adrian L. (2018) Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer. Cell Metabolism, 28 (5). 679-688.e4. ISSN 1550-4131

Breast cancer

Arif, Khalid (2014) Evaluation of hormonal receptors in breast cancer drug therapy. PhD thesis, University of Lincoln.

Hussain, Issam, Arif, Khalid, Rea, Carol and El-Sheemy, Mohamed (2013) Stemnes’ protein level: a surrogate marker for tamoxifen resistance beast cancer. In: International Society for Stem Cell Research (ISSCR ) 11th Annual Meeting, 12-15 June 2013, Boston, MA, USA.

Ray, Swagat (2010) Growth Factor Pathways in Development of Endocrine Resistance in Human Breast Cancer Cells. PhD thesis, University of Reading.

Brightfield

Lupica, G., Allinson, Nigel and Botchway, S. W. (2008) Hybrid image processing technique for the robust identification of unstained cells in bright-field microscope images. In: 2008 International Conference on Computational Intelligence for Modelling Control and Automation, CIMCA 2008, 10 - 12 December 2008, Vienna, Austria.

C90rf72

CCL2 protein, human

CDC73

Herr, Patrick, Lundin, Cecilia, Evers, Bastiaan, Ebner, Daniel, Bauerschmidt, Christina, Kingham, Guy, Palmai-Pallag, Timea, Mortusewicz, Oliver, Frings, Oliver, Sonnhammer, Erik and Helleday, Thomas (2015) A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair. Cell Discovery . p. 15034. ISSN 2056-5968

CFTR

Cai, Zhiwei, Palmai-Pallag, Timea, Khuituan, Pissared, Mutolo, Michael J, Boinot, Clément, Liu, Beihui, Scott-Ward, Toby S, Callebaut, Isabelle, Harris, Ann and Sheppard, David N (2015) Impact of the F508del mutation on ovine CFTR, a Cl- channel with enhanced conductance and ATP-dependent gating. Journal of Physiology, 593 (11). pp. 2427-2446. ISSN 0022-3751

CHO Cells

CHO cell line

CO2 laser

Waugh, David, Lawrence, Jonathan, Morgan, David and Thomas, Carolyn (2009) Interaction of CO2 laser-modified nylon with osteoblast cells in relation to wettability. Materials Science and Engineering C: Materials for Biological Applications, 29 (8). pp. 2514-2524. ISSN 0928-4931

CPEO

CaSR

Caco2 cell

Parry, Simon, Sutton-Smith, Mark, Heal, Paul, Leir, Shih-Hsing, Palmai-Pallag, Timea, Morris, Howard R., Hollingsworth, Michael A., Dell, Anne and Harris, Ann (2005) Evaluation of MUC6 mucin tandem repeats. BBA - Biochimica et Biophysica Acta - General Subjects, 1722 (1). pp. 77-83. ISSN 0006-3002

Cadherin

Calcimimetic

Calcium

Calcium ?-cell Islet

Calcium Channel Blockers

Calcium Channels

Calcium-Calmodulin-Dependent Protein Kinases,Calcium-Calmodulin-Dependent Protein Kinases: anta,Cell Count,Cell Line,Cell Proliferation,Cell Proliferation: drug effects,Chromones,Chromones: pharmacology,Culture Media,Cultured,Dose-Response Relationship,Dr

Ray, Swagat, Fry, Michael J and Darbre, Philippa D (2011) Enhanced sensitivity to rapamycin following long-term oestrogen deprivation in MCF-7, T-47-D and ZR-75-1 human breast cancer cells. The Journal of Endocrinology, 208 (1). pp. 21-9. ISSN 1479-6805

Carbachol

Carboxyfluorescein

Potter, Joe, Price, Gareth, Cliff, Chelsy, Williams, Bethany, Hills, Claire and Squires, Paul (2021) Carboxyfluorescein Dye Uptake to Measure Connexin-mediated Hemichannel Activity in Cultured Cells. Manual. Bio-Protocol, Bio-Protocol.

Carcinogens

Cas9

Emmanouilidis, Ioannis, Fili, Natalia, Cook, Alexander W., Hari-Gupta, Yukti, Dos Santos, Ália, Wang, Lin, Martin-Fernandez, Marisa L., Ellis, Peter I. J. and Toseland, Christopher P. (2021) A Targeted and Tuneable DNA Damage Tool Using CRISPR/Cas9. Biomolecules, 11 (2). p. 288. ISSN 2218-273X

Caspase-3

Cell Communication

Price, Gareth, Potter, Joe, Williams, Bethany M., Cliff, Chelsy L., Squires, Paul and Hills, Claire (2020) Connexin mediated cell communication in the kidney, a potential therapeutic target for future intervention of diabetic kidney disease? Experimental Physiology, 105 (2). pp. 219-229. ISSN 0958-0670

Cell Culture Techniques

Cell Line

Cell Line, Tumor

Cell Membrane

Li, Jian-Mei, Fan, Lampson M., Christie, Michael R. and Shah, Ajay M. (2005) Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: Role of p47phox phosphorylation and binding to TRAF4. Molecular and cellular biology, 25 (6). pp. 2320-2330. ISSN 0270-7306, 1098-5549

Cell Nucleus

Cell Separation

Cell adhesion

Cell biology

Cell communication

Hills, Claire, Price, Gareth and Squires, Paul (2016) Connexins and gap-junction mediated intercellular communication in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

Hills, Claire, Price, Gareth and Squires, Paul (2017) A role for ATP in tubular fibrosis in the diabetic kidney. In: Diabetes AGM, 08/03/2017 - 10/03/2017, Manchester.

Hills, Claire, Price, Gareth, Yiu, Stella, Tang, Sydney C and Squires, Paul (2017) A ROLE FOR CONNEXIN MEDIATED CELL COMMUNICATION IN FIBROSIS OF TUBULAR EPITHELIAL CELLS IN THE DIABETIC KIDNEY. In: EASD 2017, Sept 2017, Lisbon.

Price, Gareth, Kaufman, TJ, Wall, MJ, Squires, Paul and Hills, Claire (2017) Transforming growth factor and intercellular communication in tubular epithelial cells: a role in diabetic nephropathy. In: Diabetes UK AGM, 08/03/2017 - 10/03/2019, Manchester.

Cell cycle

Cell longevity

Castillo-Morales, Atahualpa, Monzón-Sandoval, Jimena, Urrutia, Araxi O. and Gutierrez, Humberto (2019) Postmitotic cell longevity–associated genes: a transcriptional signature of postmitotic maintenance in neural tissues. Neurobiology of Aging, 74 . pp. 147-160. ISSN 0197-4580

Cell morphology

Cell surface morphology

Cell surface roughness

Cell viability

Cell-free DNA

Palmai-Pallag, Timea and Bachrati, Csanad (2014) Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle. Microbes and Infection, 16 (10). pp. 822-832. ISSN 1286-4579

Cell-to-cell communication

Cells, Cultured

Cellular processes

Pfister, Sophia X., Ahrabi, Sara, Zalmas, Lykourgos-Panagiotis, Sarkar, Sovan, Aymard, François, Bachrati, Csanad, Helleday, Thomas, Legube, Gaëlle, LaThangue, Nicholas B., Porter, Angrew C. G. and Humphrey, Timothy C. (2014) SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability. Cell Reports, 7 (6). pp. 2006-2018. ISSN 2211-1247

Cellular uptake

Chemokine CCL2

Chloroquine

Eves, Paula, Smith-Thomas, Linda, Hedley, Susan, Wagner, Mark, Balafa, Chariklia and MacNeil, Sheila (1999) A comparative study of the effect of pigment on drug toxicity in human choroidal melanocytes and retinal pigment epithelial cells. Pigment Cell Research, 12 (1). pp. 22-35. ISSN 0893-5785

Cholesteryl esters

Choroidal melanocytes

Chronic kidney disease

Colicin

Lancaster, Lorna, Wintermeyer, Wolfgang and Rodnina, Marina (2007) Colicins and their potential in cancer treatment. Blood, Cells, Molecules and Diseases, 38 (1). pp. 15-18. ISSN 1079-9796

Connexin 43

Roger, Elena, Chadjichristos, Christos, Kavvadas, Panagiotis, Price, Gareth, Cliff, Chelsy, Hadjadj, Safia, Renciot, Jessy, Squires, Paul and Hills, Claire (2023) Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury. Cell Communication & Signaling, 21 . p. 263. ISSN 1478-811X

Connexin-43

Cliff, CL, Williams, Bethany, Hills, Claire and Squires, Paul (2023) Tonabersat breaks the cycle of Cx43- hemichannel mediated activity and NLRP3 inflammasome activation in a model of diabetic nephropathy. In: Diabetes UK AGM, 26th-28th April 2023, Liverpool.

Cliff, Chelsy L, Williams, Bethany, Chadjichristos, Christos E, Mouritzen, Ulrik, Squires, Paul E and Hills, Claire E (2022) Connexin 43: A target for the treatment of inflammation in secondary complications of the kidney and eye in diabetes. International Journal of Molecular Sciences, 23 (600). ISSN 1422-0067

Williams, B., Cliff, C.L., Ward, J.K., Squires, P. and Hills, C. (2023) Blocking connexin-43 hemichannels reduces high glucose-evoked nod- like receptor protein-3 inflammasome activation in a model of diabetic nephropathy. (Winner - Diabetes UK Basic Science Poster Award). In: Diabetes UK Professional Conference 2023, 26th to 28th April 2023, Liverpool, UK.

Williams, Bethany M, Cliff, Chelsy L, Demirel, Isak, Squires, Paul and Hills, Claire (2022) Blocking connexin 43 hemichannel-mediated ATP release reduces communication within and between tubular epithelial cells and medullary fibroblasts in a model of diabetic nephropathy. Diabetic Medicine (e14963). ISSN 1464-5491

Connexins

Cricetulus

Cytochrome P-450 CYP1A2

Cytokines

Cytoskeleton

Dos Santos, Ália, Fili, Natalia, Hari-Gupta, Yukti, Gough, Rosemarie E., Wang, Lin, Martin-Fernandez, Marisa, Aaron, Jesse, Wait, Eric, Chew, Teng-Leong, Toseland, Christopher P., UNSPECIFIED and UNSPECIFIED (2022) Binding partners regulate unfolding of myosin VI to activate the molecular motor. The Biochemical Journal, 479 (13). pp. 1409-1428. ISSN 0264-6021

DJ-1

Bjørkblom, Benny, Maple-Grødem, Jodi, Puno, Marc Rhyan, Odell, Mark, Larsen, Jan Petter and Geir-Moller, Simon (2014) ROS-mediated DJ-1 monomerization modulates intracellular trafficking involving Karyopherin-2. Molecular and Cellular Biology, 34 (16). pp. 3024-3040. ISSN 0270-7306

DM1

DNA (apurinic or apyrimidinic site) lyase

DNA Adducts

DNA Polymerase beta

DNA Repair

Abugable, Arwa A., Morris, Julia L.M., Palminha, Nelma M., Zaksauskaite, Ringaile, Ray, Swagat and El-Khamisy, Sherif F. (2019) DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms. DNA Repair . ISSN 15687864

DNA adduct

DNA catenation

Nielsen, Christian F., Huttner, Diana, Bizard, Anna H., Hirano, Seiki, Li, Tian-Neng, Palmai-Pallag, Timea, Bjerregaard, Victoria A., Liu, Ying, Nigg, Erich A., Wang, Lily Hui-Ching and Hickson, Ian D. (2015) PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis. Nature Communications, 6 . p. 8962. ISSN 2041-1723

DNA damage

Ray, Swagat, Chakrabarty, Sanjiban and Chaudhuri, Arnab Ray (2023) Editorial: Impact of genome instability on human health. Frontiers in Molecular Biosciences, 10 . ISSN 2296-889X

DNA damage response

Karyka, Evangelia, Berrueta Ramirez, Nelly, Webster, Christopher P., Marchi, Paolo M., Graves, Emily J., Godena, Vinay K., Marrone, Lara, Bhargava, Anushka, Ray, Swagat, Ning, Ke, Crane, Hannah, Hautbergue, Guillaume M., El-Khamisy, Sherif F. and Azzouz, Mimoun (2022) SMN-deficient cells exhibit increased ribosomal DNA damage. Life Science Alliance, 5 (8). ISSN 2575-1077

Palmai-Pallag, Timea and Bachrati, Csanad (2014) Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle. Microbes and Infection, 16 (10). pp. 822-832. ISSN 1286-4579

Ray, Swagat, Abugable, Arwa A., Parker, Jacob, Liversidge, Kirsty, Palminha, Nelma M., Liao, Chunyan, Acosta-Martin, Adelina E., Souza, Cleide D. S., Jurga, Mateusz, Sudbery, Ian and El-Khamisy, Sherif F. (2022) A mechanism for oxidative damage repair at gene regulatory elements. Nature, 609 . pp. 1038-1047. ISSN 0028-0836

DNA damages

DNA directed DNA polymerase beta

DNA intercalators

Andrews, William J, Ray, Swagat, Panova, Tatiana, Engel, Christoph and Panov, Konstantin I (2021) DNA Intercalators Inhibit Eukaryotic Ribosomal RNA Synthesis by Impairing the Initiation of Transcription. Genes, 12 (9). ISSN 2073-4425

DNA repair

DNA replication

Xing, Meichun, Wang, Xiaohui, Palmai-Pallag, Timea, Shen, Huahao, Helleday, Thomas, Hickson, Ian D. and Ying, Songmin (2015) Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget, 6 (35). pp. 37638-37646. ISSN 1949-2553

Ying, Songmin, Minocherhomji, Sheroy, Chan, Kok Lung, Palmai-Pallag, Timea, Chu, Wai Kit, Wass, Theresa, Mankouri, Hocine W., Liu, Ying and Hickson, Ian D. (2013) MUS81 promotes common fragile site expression. Nature Cell Biology, 15 (8). pp. 1001-1007. ISSN 1465-7392

Dendritic cells

Gaspar, Miguel, May, Janet S., Sukla, Soumi, Frederico, Bruno, Gill, Michael B., Smith, Christopher M., Belz, Gabrielle T. and Stevenson, Philip G. (2011) Murid herpesvirus-4 exploits dendritic cells to infect B cells. PLoS Pathogens, 7 (11). ISSN 1553-7366

Dermis

Eves, Paula, Katerinaki, Efthymia, Simpson, Claire, Layton, Christopher, Dawson, Rebecca, Evans, Gareth and MacNeil, Sheila (2003) Melanoma invasion in reconstructed human skin is influenced by skin cells - Investigation of the role of proteolytic enzymes. Clinical and Experimental Metastasis, 20 (8). pp. 685-700. ISSN 0262-0898

Detection rates

Development

Lobner, Kristian, Steinbrenner, Holger, Roberts, Graham A, Ling, Zhidong, Huang, Guo-Cai, Piquer, Sandra, Pipeleers, Daniel G, Seissler, Jochen and Christie, Michael R. (2002) Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets. Relationship to development of insulin secretory responses in early life. Diabetes, 51 (10). pp. 2982-2988. ISSN 0012-1797

Diabetes

Gomez, E., Powell, M.L., Bevington, A. and Herbert, T. P. (2008) A decrease in cellular energy status stimulates PERK-dependent eIF2α phosphorylation and regulates protein synthesis in pancreatic β-cells. Biochemical Journal, 410 (3). pp. 485-493. ISSN 0264-6021

Greenman, I. C., Gomez, E., Moore, C. E. J. and Herbert, T. P. (2005) The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic β-cells. Biochemical Journal, 391 (2). pp. 291-300. ISSN 0264-6021

Potter, Joe, Price, Gareth, Hills, Claire and Squires, Paul (2019) A role for Collagen I in regulating Connexin-43 mediated hemichannel activity in the proximal region of the diabetic kidney. In: EASD 2019, 17/09/2019 - 20/09/2019, Barcelona.

Diabetes Mellitus, Type 2

Diabetic nephropathy

Williams, Bethany M, Cliff, Chelsy L, Lee, Kelvin, Squires, Paul and Hills, Claire (2022) The Role of the NLRP3 Inflammasome in Mediating Glomerular and Tubular Injury in Diabetic Nephropathy. Frontiers in Physiology (Metabolic Physiology), 13 (907504). ISSN 1664-042X

Dose-Response Relationship, Drug

Double-strand break resection

Dye uptake

EB1

ECM proteins

MacNeil, Sheila, Eves, Paula, Richardson, Ben, Molife, Rhoda, Lorigan, Paul, Wagner, Mark, Layton, Chris, Morandini, Renato and Ghanem, Ghanem (2000) Oestrogenic steroids and melanoma cell interaction with adjacent skin cells influence invasion of melanoma cells in vitro. Pigment Cell & Melanoma Research, 13 (8). pp. 68-72. ISSN 0893-5785

ELISA

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

EME1

Elasticity

Elov13 protein

Embryonic Stem Cells

Dobbin, Edwina, Graham, Ciaren, Corrigan, Pamela M., Thomas, Keith G., Freeburn, Robin W. and Wheadon, Helen (2009) Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways. Experimental Hematology, 37 (9). pp. 111-121. ISSN 0301-472x

Enc1

Endothelium, Vascular

Epithelial cells

Evolution, Molecular

Excimer laser

Waugh, David and Lawrence, Jonathan (2010) Using UV laser surface treatment to modify the wettability characteristics of polyamide 6,6 and its effects on osteoblast cell activity. In: ICALEO 2010, 26th - 30th November 2010, Anaheim, CA, USA.

Waugh, David and Lawrence, Jonathan (2011) Wettability and osteoblast cell response modulation through UV laser processing of nylon 6,6. Applied Surface Science, 257 (21). pp. 8798-8812. ISSN 0169-4332

Exosomes

Expert knowledge

Extracellular matrix protein

Potter, Joe, Price, Gareth, Cliff, Chelsy L, Williams, Bethany M, Hills, Claire and Squires, Paul (2020) Inhibition of intern A2B1 negates collagen-1 induced changes in connexion-mediated hemichannel activity in an in vitro model of diabetic nephropathy. In: Diabetes UK AGM, Online.

Extracellular signal-regulated kinase

FANCD2

FGF2

Fernig, D. G. and Stewart, Paul (2011) Heparan sulfate determines the modes of diffusion of fibroblast growth factor 2 within the pericellular matrix. In: ICMAT2011 International Conference on Materials for Advanced Technologies, 26 Jun - 1 Jul 2011, Suntec, Singapore.

FGF2 diffusion

FTIR

Fast atom bombardment mass spectrometry

Female

Fibrillarin

Fibrosis

Flow cytometry

Fluorescence

Fili, Natalia and Toseland, Christopher P (2014) Fluorescence and labelling: how to choose and what to do. In: Fluorescent Methods for Molecular Motors. Springer Nature, pp. 1-24. ISBN 9783034808569

Fluorometry

Fluorophores

Forskolin

Fracture

Sloan, Andrew, Hussain, Issam, Maqsood, Mohmeed, Eremin, Oleg and El-Sheemy, Mohamed (2009) Inhibition of fracture healing in smokers: cellular and molecular aspects. In: Society of Academic and Research Surgery (SARS) Annual Conference, 7-8 January 2009, Bristol.

Fracture healing

Sloan, Andrew (2013) Inhibition of the fracture healing process in smokers: deregulation of cellular and molecular milieu in tibial fracture micro-environment. PhD thesis, University of Lincoln.

Sloan, Andrew, Hussain, Issam, Maqsood, Mohmeed, Eremin, Oleg and El-Sheemy, Mohamed (2010) The effects of smoking on fracture healing. The Surgeon, 8 (2). pp. 111-116. ISSN 1479-666X

Functional genomics

Fura-2

GASC

Gap junctions

Gastrins

Gene Expression Data

Gene coexpression network

Gene expression

Gene regulation

Genetics

Glioma

Glyburide

Granulosa Cells

Lee, P. S. N., Squires, Paul, Buchan, A. M. J., Yuen, B. H. and Leung, P. C. K. (1996) P 2-purinoreceptor evoked changes in intracellular calcium oscillations in single isolated human granulosa-lutein cells. Endocrinology, 137 (9). pp. 3756-3761. ISSN 0013-7227

Ground truth

Growth Factor

HEK293 Cells

HEK293 cell line

HMOX1 protein, human

HSP90

Escalante, Susana Gómez, Brightmore, Joseph A., Piper, Peter W. and Millson, Stefan H. (2018) UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM. Cell Stress and Chaperones, 23 (4). pp. 609-615. ISSN 1355-8145

Gomez-Escalante, Susana, Piper, Peter W. and Millson, Stefan H. (2017) Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival. Cell Stress and Chaperones, 22 (1). pp. 135-141. ISSN 1355-8145

Haematoma

Sloan, Andrew, Hussain, Issam, Jelly, Neil, Sharma, Vikas, Maqsood, Mohmeed, Eremin, Oleg and El-Sheemy, Mohamed (2009) Inhibition of tibial fracture healing in smokers: cellular and molecular aspects. In: The 19th Conference of the European Wound Management Association (EWMA) in cooperation with the Finnish Wound Care Society FWCS, 20-22 May 2009, Helsinki.

Haematopoietic Stems Cell

Hussain, Issam, Magd, Salah A., Eremin, Oleg and El-Sheemy, Mohamed (2012) New approach to isolate mesenchymal stem cells (MSC) from human umbilical cord blood. Cell Biology International, 36 . pp. 595-600. ISSN 1065-6995

Heamatopiotic stem cells

Hussain, Issam, Maged, Salah, Eremin, Oleg and El-Sheemy, Mohamed (2009) Effective isolation of mesenchymal stem cells from human umbilical cord blood. In: World Stem Cell Summit, 21-23 September 2009, Baltimore (Maryland, USA).

Helicase

Heme Oxygenase-1

Hemichannels

Heparan Sulphate

Hepatocytes

Heterogeneity;

Marsh, Katrina A., Stamp, Gordon W. H. and Kirkland, Susan C. (1993) Isolation and characterization of multiple cell types from a single human colonic carcinoma: Tumourigenicity of these cell types in a xenograft system. Journal of Pathology, 170 (4). pp. 441-450. ISSN 0022-3417

High variability

High-throughput

Histone modification

Holliday junctions

Homologous recombination repair

Hormonal receptors

Arif, Khalid (2014) Evaluation of hormonal receptors in breast cancer drug therapy. PhD thesis, University of Lincoln.

Hsp90

Piper, Peter William, Scott, Julia Elizabeth and Millson, Stefan Heber (2022) UCS Chaperone Folding of the Myosin Head: A Function That Evolved before Animals and Fungi Diverged from a Common Ancestor More than a Billion Years Ago. Biomolecules, 12 (8). p. 1028. ISSN 2218-273X

Willhoft, Oliver, Kerr, Richard, Patel, Dipali, Zhang, Wenjuan, Al-Jassar, Caezar, Daviter, Tina, Millson, Stefan H., Thalassinos, Konstantinos and Vaughan, Cara K. (2017) The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores. Scientific Reports, 7 (1). p. 41626. ISSN 2045-2322

Hsp90; MAP kinase; Slt2(Mpk1); Transcription activation; Yeast.

Millson, Stefan H., Truman, Andrew W. and Piper, Peter W. (2022) Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast. Cell Stress and Chaperones, 27 (3). pp. 295-304. ISSN 1466-1268

Human

Eves, Paula, Layton, C., Hedley, S., Dawson, R. A., Wagner, M., Morandini, R., Ghanem, G. and MacNeil, S. (2000) Characterization of an in vitro model of human melanoma invasion based on reconstructed human skin. British Journal of Dermatology, 142 (2). pp. 210-222. ISSN 0007-0963

Human Umbilical Cord Blood

Hussain, Issam, Maged, Salah, Sloan, Andrew, Eremin, Oleg and El-Sheemy, Mohamed (2009) Novel approach for effective isolation of mesenchymal stem cells from human umbilical cord blood. In: European Society for Surgical Research (ESSR); 44th Congress, 19-24 May 2009, Nimes, France.

Human Umbilical cord Blood

Hussain, Issam, Sloan, Andrew, Magd, Salah, Eremin, Oleg and El-Sheemy, Mohamed (2009) Novel approach of effective isolation of mesenchymal stem cells from human umbilical cord blood. In: 5th Joint Meeting of the European Tissue Repair Society and the Wound Healing Society, 25-29 August 2009, Limoges-France.

Human airway smooth muscle cells

Kaur, Manminder, Holden, Neil S., Wilson, Sylvia M., Sukkar, Maria B., Chung, Kian Fan, Barnes, Peter J., Newton, Robert and Giembycz, Mark A. (2008) Effect of β2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A. American journal of physiology. Lung cellular and molecular physiology, 295 (3). L505-L514. ISSN 1040-0605

Human brain development

Human umbilical cord blood

Hussain, Issam, Sloan, Andrew, Eremin, Oleg and El-Sheemy, Mohamed (2009) Novel approach for effective isolation of mesenchymal stem cells from human umbilical cord blood. In: European Society for Surgical Research (ESSR) Proceedings Book. European Society for Surgical Research (ESSR). ISBN 9788875875060

Hussain, Issam, Sloan, Andrew, Maged, Salah, Eremin, Oleg and El-Sheemy, Mohamed (2011) Effective isolation of mesenchymal stem cells from human umbilical cord blood: a novel approach. In: Biomedical Science Congress IBMS, 26-28 September 2011, Birmingham.

Humans

Hybrid image

IL33 protein, human

IL6 protein, human

Identification (control systems)

Image processing

Image processing algorithm

Imaging systems

Imidazoles

Immunohistochemistry

Indentation

Infectious disease

Infectious diseases

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Inflammation

Palmai-Pallag, Timea and Bachrati, Csanad (2014) Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle. Microbes and Infection, 16 (10). pp. 822-832. ISSN 1286-4579

Zhu, N., Lalla, R., Eves, Paula, Brown, T.La H., King, A., Kemp, E. H., Haycock, J. W. and MacNeil, S. (2004) Melanoma cell migration is upregulated by tumour necrosis factor-α and suppressed by α-melanocyte-stimulating hormone. British Journal of Cancer, 90 (7). pp. 14573-1463. ISSN 0007-0920

Zhu, Ningwen, Eves, Paula, Katerinaki, Effie, Szabo, Marika, Morandini, Renato, Ghanem, Ghanem, Lorigan, Paul, Haycock, John W. and MacNeil, Sheila (2002) Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor α and suppressed by α melanocyte stimulating hormone. Journal of Investigative Dermatology, 119 (5). pp. 1165-1171. ISSN 0022-202X

Innervation

Insulin

Insulin sensitivity

Insulin-Secreting Cells

Dunne, M. J., Harding, E. A., Jaggar, J. H., Ayton, B. J. and Squires, Paul (1995) Endogenous and chemical activators of ATP-regulated potassium channels in insulin secreting cells: possible mechanisms and physiological significance. In: Frontiers of insulin secretion and pancreatic B-cell research. Smith-Gordon, London. ISBN 9781854631046

Dunne, M. J., Jaggar, J. H., Harding, E. A., Kane, C. and Squires, Paul E. (1996) Potassium channels in pancreatic beta-cells: modulation, pharmacology and their role in the regulation of insulin secretion. In: Potassium channels and their modulators: from synthesis to clinical experience. The Taylor & Francis series in pharmaceutical sciences . CRC Press/Taylor & Francis, pp. 369-405. ISBN 9780748405572

Dunne, M. J., Jaggar, J. H., Harding, E. A. and Squires, Paul (1995) Protein kinase C and modulation of ion channel activity in insulin-secreting cells. In: Frontiers of insulin secretion and pancreatic B-cell research. Smith-Gordon, London. ISBN 9781854631046

Integrin

Integrins

Intercellular Adhesion Molecule-1

Interleukin-23

Interleukin-6

Interleukins

Intracellular Membranes

Invasion

Invasion models

Islets of Langerhans

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

Isothiocyanates

JCNotOpen

JCOpen

Monzón-Sandoval, Jimena, Castillo-Morales, Atahualpa, Crampton, Sean, McKelvey, Laura, Nolan, Aoife, O’Keeffe, Gerard and Gutierrez, Humberto (2015) Modular and coordinated expression of immune system regulatory and signaling components in the developing and adult nervous system. Frontiers in Cellular Neuroscience, 9 . ISSN 1662-5102

Nyathi, Yvonne and Pool, Martin R. (2015) Analysis of the interplay of protein biogenesis factors at the ribosome exit site reveals new role for NAC. Journal of Cell Biology, 210 (2). pp. 287-301. ISSN 0021-9525

Kidney

Kinetochores

LIG3

Labelling

Liquid crystals

Low contrast

MEK/ERK

MUC1

Silverman, Howard S, Sutton-Smith, Mark, Heal, Paul, Parry, Simon, Palmai-Pallag, Timea, Leir, Shih-Hsing, Morris, Howard R, Dell, Anne and Harris, Ann (2002) In vivo glycosylation of MUC1 in airway epithelial cells. Glycoconjugate journal, 19 (6). pp. 379-84. ISSN 0282-0080

MUC12

Palmai-Pallag, Timea, Khodabukus, Naila, Kinarsky, Leo, Leir, Shih-Hsing, Sherman, Simon, Hollingsworth, Michael A. and Harris, Ann (2005) The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins. FEBS Journal, 272 (11). pp. 2901-2911. ISSN 1742-464X

MUC3

MUC6 mucin

MUS81

Malaria

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Male

Mass Spectrometry

Matrix metalloproteinases

Mechanism of action

Melano cortin

Melanocortin

Melanocortin; Signal Transduction

Melanoma

Membrane Transport Proteins

Membranolysis

Dennison, Sarah R., Harris, Frederick, Mura, Manuela and Phoenix, David A. (2018) An atlas of anionic antimicrobial peptides from amphibians. Current Protein & Peptide Science, 19 . ISSN 1389-2037

Mesenchymal stem cell

Mesenchymal stem cells

Mukonoweshuro, Blessing, Brown, Christopher JF, Fisher, John and Ingham, Eileen (2014) Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells. Journal of Tissue Engineering, 5 . p. 204173141453425. ISSN 20417314

Sloan, Andrew, Hussain, Issam, Maqsood, Mohmeed, Eremin, Oleg and El-Sheemy, Mohamed (2010) Molecular and cellular aspects of smoking on fracture healing: a comparison of two models. In: Society for Surgical Research Meeting--ESSR, Geneva.

Sloan, Andrew, Hussain, Issam, Maqsood, Mohmeed, Eremin, Oleg and El-Sheemy, Mohamed (2010) The effects of smoking on fracture healing. The Surgeon, 8 (2). pp. 111-116. ISSN 1479-666X

Metabolic pathway

Metabolism

Metformin

Mice

Microcirculation

Microhomology-mediated end-joining

Microscope images

Microscopes

Microtubules

Mislocalised proteins

Mitochondrial complexes

Mitochondrial dysfunction

Mitogen-Activated Protein Kinase 1

Mitogen-Activated Protein Kinase 3

Model

Molecular Biology

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Molecular Sequence Data

Multi-photon absorption

Multiphoton processes

Muscarinic acetylcholine receptor

Mutation

Myosin VI

Hari-Gupta, Yukti, Fili, Natalia, Dos Santos, Ália, Cook, Alexander W, Gough, Rosemarie E, Reed, Hannah C W, Wang, Lin, Aaron, Jesse, Venit, Tomas, Wait, Eric, Grosse-Berkenbusch, Andreas, Gebhardt, J Christof M, Percipalle, Piergiorgio, Chew, Teng-Leong, Martin-Fernandez, Marisa and Toseland, Christopher P (2022) Myosin VI regulates the spatial organisation of mammalian transcription initiation. Nature Communications, 13 (1). p. 1346. ISSN 2041-1723

Myosins

Fili, Natalia and Toseland, Christopher P. (2019) Unconventional Myosins: How Regulation Meets Function. International Journal of Molecular Sciences, 21 (1). ISSN 1422-0067

NAC

NADPH Dehydrogenase

NADPH Oxidase

NANOG

NBS1

NDP52

Fili, Natalia, Hari-Gupta, Yukti, Dos Santos, Ália, Cook, Alexander, Poland, Simon, Ameer-Beg, Simon M., Parsons, Maddy and Toseland, Christopher P. (2017) NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription. Nature Communications, 8 (1). p. 1871. ISSN 2041-1723

NEXAFS; Plasma copolymer; Protonated amine; XPS

Beck, A. J., Whittle, J. D., Bullet, N. A., Eves, P., MacNeil, S, McArthur, S. L. and Shard, A. G. (2005) Plasma co-polymerisation of two strongly interacting monomers: acrylic acid and allylamine. Plasma Processes and Polymers, 2 (8). pp. 641-649. ISSN 1612-8850

NF-kappaB

NLRP3

NS1

Pereira, Carina F, Wise, Helen M., Kurian, Dominic, Pinto, Rute M., Amorim, Maria J, Gill, Andrew and Digard, Paul (2018) Pleiotropic effects of mutations in the effector domain of influenza A virus NS1 protein. BMC Research Notes, 11 (673). ISSN 1756-0500

Nephropathy

Price, Gareth, Siamantouras, Eleftherios, Potter, Joe, Squires, Paul and Hills, Claire (2019) Purinergic receptor (P2X7) activation contributes to disassembly of adherens & tight junctions in tubular epithelial cells of the diabetic kidney. In: EASD 2019, 17/09/2019 - 20/09/2019, Barcelona.

Neural maintenance

Neurology

Neuroscience

Nitrendipine

NotOAChecked

Palmai-Pallag, Timea and Bachrati, Csanad (2014) Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle. Microbes and Infection, 16 (10). pp. 822-832. ISSN 1286-4579

Novel Method

Novel method

Nuclear export

Nucleic acids, Cells

Nucleolus

O-glycosylation

Leir, Shih-Hsing, Parry, Simon, Palmai-Pallag, Timea, Evans, Joanne, Morris, Howard R, Dell, Anne and Harris, Ann (2005) Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression. American Journal of Respiratory Cell and Molecular Biology, 32 (5). pp. 453-61. ISSN 1044-1549

OCT3-4

Obesity

Oestradiol

Osmolar Concentration

Osmosis

Osteoblast cells

Oxidation-Reduction

Oxidative DNA damage

Palmai-Pallag, Timea and Bachrati, Csanad (2014) Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle. Microbes and Infection, 16 (10). pp. 822-832. ISSN 1286-4579

Oxidative stress

P2X7

PABP

Ray, Swagat and Anderson, Emma C. (2016) Stimulation of translation by human Unr requires cold shock domains 2 and 4, and correlates with poly(A) binding protein interaction. Scientific Reports, 6 (1). p. 22461. ISSN 2045-2322

PARP inhibition (PARPi)

Ray, Swagat, Chakrabarty, Sanjiban and Chaudhuri, Arnab Ray (2023) Editorial: Impact of genome instability on human health. Frontiers in Molecular Biosciences, 10 . ISSN 2296-889X

PET

PI3K

PICH

POLG

Panc1 cell

Pancreas

Pancreatic Neoplasms

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

Pancreatic beta cells

Pancreatic islets

Parafibromin

Parasitology

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Parkinson's disease

Peptide 5

Peptide5

Williams, BM, Squires, PE, Cliff, CL, Potter, JA and Hills, CE (2021) Peptide 5 blocks Connexin-43 hemichannels to prevent secretion of inflammatory and fibrotic mediators in TGFbeta1 treated human primary proximal tubule cells. In: Diabetes UK AGM, 19-30 April 2021, Online.

Pharmacodynamic

Phosphoproteins

Physiology

Polymerase Chain Reaction

Potassium Channel Blockers

Potassium Channels

Prostaglandins

Proteasomes

Protein Transport

Protein biogenesis

Protein degradation

Protein synthesis

Protein targeting

Protein translocation

Proteins

Proteomics

Protoporphyrins

Protozoa

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Pyloric Antrum

RAD51

RIG-I

RNA

RNA Polymerase II

RNA polymerase I

RNA polymerase II

RNA, Messenger

RNA, Small Interfering

RNAseq

Andreani, N. A., Renzi, S., Piovani, G., Ajmone Marsan, P., Bomba, L., Villa, R., Ferrari, M. and Dotti, S. (2017) Potential neoplastic evolution of Vero cells: in vivo and in vitro characterization. Cytotechnology, 69 (5). pp. 741-750. ISSN 0920-9069

RPE cells

Raman Spectroscopy

Subramanian, Gomathy, Stylianou, Con, Phang, In Yee, Cool, Simon, Nurcombe, Victor, Lear, Martin, Gorelik, Sergey, Fernig, David and Hobley, Jonathan (2020) Raman mapping glucose metabolites during human mesenchymal stem cell adipogenesis. bioRxiv .

Rats

Reactive Oxygen Species

Reactive oxygen species

Palmai-Pallag, Timea and Bachrati, Csanad (2014) Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle. Microbes and Infection, 16 (10). pp. 822-832. ISSN 1286-4579

Receptor

Receptors, Adiponectin

Receptors, Purinergic

Recombinant proteins

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Red cell

Redox chemistry

Al-Saryi, N. A., Al-Hejjaj, M. Y., Van Roermund, C. W. T., Hulmes, G. E., Ekal, L., Payton, C., Wanders, R. J. A. and Hettema, E. H. (2017) Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae. Scientific Reports, 7 (1). ISSN 2045-2322

Reflexion coefficient

Regulation

Fili, Natalia and Toseland, Christopher P. (2019) Unconventional Myosins: How Regulation Meets Function. International Journal of Molecular Sciences, 21 (1). ISSN 1422-0067

Renal fibrosis

Representative sample

Reverse Transcriptase Polymerase Chain Reaction

Ribonuclease

Lancaster, Lorna, Wintermeyer, Wolfgang and Rodnina, Marina (2007) Colicins and their potential in cancer treatment. Blood, Cells, Molecules and Diseases, 38 (1). pp. 15-18. ISSN 1079-9796

Ribosome

Robotic systems

Robust identification

Robust technique

SCAN1,TDP,UCHL3,aging,cancer,heart failure,myocardial infarction,neurodegeneration,rhabdosarcoma,topoisomerase

Liao, Chunyan, Beveridge, Ryan, Hudson, Jessica J.R. R, Parker, Jacob D., Chiang, Shih-Chieh Chieh, Ray, Swagat, Ashour, Mohamed E., Sudbery, Ian, Dickman, Mark J. and El-Khamisy, Sherif F. (2018) UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. Cell Reports, 23 (11). pp. 3352-3365. ISSN 2211-1247

SEA

SMN

SNAP-tag technology

Yang, Peng-Yu, Liu, Kai, Zhang, Chongjing, Chen, Grace Y. J., Shen, Yuan, Ngai, Mun Hong, Lear, Martin J. and Yao, Shao Q. (2011) Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry - An Asian Journal, 6 (10). pp. 2762-2775. ISSN 1861-4728

SOX2

STAT5

Senataxin

Sgt1

She4

Signal recognition particle

Signal Transduction

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

Single molecule

Singlet Oxygen

Skp1

Smoking

Sloan, Andrew (2013) Inhibition of the fracture healing process in smokers: deregulation of cellular and molecular milieu in tibial fracture micro-environment. PhD thesis, University of Lincoln.

Sperm Motility

Spermatozoa

Sphingolipids

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Stem Cells

Stem cell, Artificial intelligence

Stemness” genes

Hussain, Issam, Arif, Khalid, Rea, Carol and El-Sheemy, Mohamed (2013) Predicting the response of tamoxifen resistance in breast cancer: stemness protein is invaluable marker. In: 48th Congress of European Society for Surgical Research ESSR, 29 May - 1 June, Istanbul, Turkey.

Stiffness

Structure

Structure-Activity Relationship

Support, Non-U.S. Gov't

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

Sympathetic neuron

TGF-beta1

TGF?

TNF Receptor-Associated Factor 4

TPR

TRIM25

Tamoxifen

Tel/PDGFRbeta

Temperature stress

Terbutaline

Terpenes

Thin layered chromatography

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Thiocyanates

Thioridazine

Tibial fracture

Time Factors

Tonabersat

Cliff, CL, Squires, PE, Williams, BM, Potter, JA and Hills, CE (2021) Blocking connexin-43 (CX43) hemichannels negates glucose-associated inflammation in clonal proximal tubular epithelial cells. In: Diabetes UK AGM, 19-30 April 2021, Online.

Topoisomerase II

Ray, Swagat, Panova, Tatiana, Miller, Gail, Volkov, Arsen, Porter, Andrew C.G. G., Russell, Jackie, Panov, Konstantin I. and Zomerdijk, Joost C.B.M. B. M. (2013) Topoisomerase IIα promotes activation of RNA polymerase i transcription by facilitating pre-initiation complex formation. Nature Communications, 4 (1). p. 1598. ISSN 2041-1723

Toxoplasmosis

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Transcription, Genetic

Transcriptional signature

Tropical Neglected diseases

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Tumor Cells, Cultured

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

Tumor Necrosis Factor Receptor-Associated Peptides and Proteins

Tumor Necrosis Factor-alpha

Tumor Necrosis Factor-alpha, Tiron

UCS Protein

UCS protein

UFBs

UNC45

Ubiquitin ligase

Ubiquitylation

Unconventional

Fili, Natalia and Toseland, Christopher P. (2019) Unconventional Myosins: How Regulation Meets Function. International Journal of Molecular Sciences, 21 (1). ISSN 1422-0067

Unr

Vaccine

Vero cells

Vitreous humor

Vivax malaria

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

Water channels

Western blotting

X box binding protein 1

Yeast

a-melanocyte stimulating hormone

acetylcholine

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

actin

adenosine 5' o (3 thiotriphosphate)

adenosine 5'-O-(3-thiotriphosphate)

adenosine diphosphate

adenosine phosphate

adenosine triphosphate

adipocyte

adiponectin

adiponectin receptor

adipose tissue

adult

airway

airway epithelium

alpha 2 adrenergic receptor blocking agent

angiogenesis

Bakshi, Hamid A, Quinn, Gerry A, Nasef, Mohamed M, Mishra, Vijay, Aljabali, Alaa A A, El-Tanani, Mohamed, Serrano-Aroca, Ángel, Webba Da Silva, Mateus, McCarron, Paul A and Tambuwala, Murtaza (2022) Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF Pathways. Cells, 11 (9). p. 1502. ISSN 2073-4409

animal

animal experiment

animal model

Williams, Sarah H., Sahota, Virender, Palmai-Pallag, Timea, Tebbutt, Scott J., Walker, Jean and Harris, Ann (2003) Evaluation of gene targeting by homologous recombination in ovine somatic cells. Molecular Reproduction and Development, 66 (2). pp. 115-25. ISSN 1098-2795

animal tissue

archaeon

Humphries, Stuart (2013) A physical explanation of the temperature dependence of physiological processes mediated by cilia and flagella. Proceedings of the National Academy of Sciences of the United States of America, 110 (36). pp. 14693-14698. ISSN 0027-8424

article

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

asthma

atropine

bacterium

binding and related phenomena

bio-sensing

bioactivity

bioactivity of NiTi

Waugh, David, Lawrence, Jonathan, Chan, C. W., Hussain, Issam and Man, H. C. (2014) Laser melting of NiTi and its effects on in-vitro mesenchymal stem cell responses. In: Laser surface engineering: processes and applications. Series in Electronic and Optical Materials . Woodhead Publishing, Cambridge. ISBN UNSPECIFIED

biochemistry

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

biosynthesis

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

blood viscosity

bmjanomaly

bmjconvert

bmjlink

bmjtype

body fluid

body weight

bone morphogenetic protein

breast cancer

breast cancer stem cell

brown adipose tissue

cRGD

cRGD-peptide

cadherin

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

caffeine

calcimimetics

calcium

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

calcium cell level

calcium channel

calcium homeostasis

calcium ion

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

calcium ions

calcium mobilization

calcium sensing receptor

calcium transport

cancer

Lancaster, Lorna, Wintermeyer, Wolfgang and Rodnina, Marina (2007) Colicins and their potential in cancer treatment. Blood, Cells, Molecules and Diseases, 38 (1). pp. 15-18. ISSN 1079-9796

Ray, Swagat, Chakrabarty, Sanjiban and Chaudhuri, Arnab Ray (2023) Editorial: Impact of genome instability on human health. Frontiers in Molecular Biosciences, 10 . ISSN 2296-889X

cancer inhibition

carbon 14

carboxypeptidase

carboxypeptidase x1

carcinogen

cell activity

cell adhesion

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

cell communication

Hills, Claire, Kerr, M, Wall, MJ and Squires, Paul (2014) Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells. In: Diabetes UK AGM, 05/03/2014 - 07/03/2014, Liverpool.

Hills, Claire, Price, Gareth, Wall, MJ, Yiu, SW, Tang, S and Squires, Paul (2017) A role for connexin mediated cell communication in fibrosis of tubular epithelial cells in the diabetic kidney. In: European Association for the Study of Diabetes, Sept 2017, Lisbon.

Price, Gareth, Squires, Paul and Hills, Claire (2016) How do cells of the diabetic kidney talk to each other? In: Rose trees Trust PhD Symposium, 21/09/2016, The Blizard Institute, Queen Mary University of London.

Squires, Paul, Price, Gareth and Hills, Claire (2016) Connexins, hemi-channels and ATP release in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

Squires, Paul, Price, Gareth, Wall, Mark J, Kaufman, Tim J and Hills, Claire (2017) The effect of transforming growth factor beta1 on cell-cell coupling and cell-to-cell communication in tubular epithelial cells of the diabetic kidney. In: European Association for the Study of Diabetes, Sept 2017, Lisbon.

cell coupling

cell culture

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

cell differentiation

cell isolation

cell line

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

cell membrane

cell membrane depolarization

cell proliferation

cell protection

cell separation

cell strain HepG2

cell stress

cell substrates

Dotti, Silvia, Lombardo, Tina, Villa, Riccardo, Cacciamali, Andrea, Zanotti, Cinzia, Andreani, Nadia, Cinotti, Stefano and Ferrari, Maura (2017) Transformation and tumorigenicity testing of simian cell lines and evaluation of poliovirus replication. PLoS ONE, 12 (1). e0169391. ISSN 1932-6203

cell survival

cell-cell coupling

cell-substrate

Hills, Claire and Squires, Paul (2015) Glucose-evoked changes in Transforming Growth Factor Beta1 modulate cell-substrate binding in human proximal tubule derived epithelial cells. In: Diabetes UK AGM, 11/03/2015 - 13/03/2015, Liverpool.

cellular distribution

cellular senescence

channel gating

chemical proteomics

chemistry

chloride channels

chromatin remodeling

chromosome instability

chromosome missegregation

chronic kidney disease

click chemistry

co-expression networks

cold exposure

collagen

colorectal cancer

colorectal carcinoma

common fragile site

concentration response

conference paper

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

confocal microscopy

connexin

connexins

controlled study

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

corpus luteum

correlation

crypsis

cryptic female choice

culture technique

cyclophilin

cystic fibrosis

cystic fibrosis transmembrane conductance regulator

cytochrome P450 1A2

cytokine

Firth, Katrina, Price, Gareth, Fletcher, Michelle, Squires, Paul and Hills, Claire (2018) Transforming growth factor beta 1 initiates activation of the NLRP3 inflammasome in human derived proximal tubule kidney cells. In: Diabetes UK AGM, 14/03/2018 - 16/03/2018, London.

cytokine production

cytokines

cytology

cytoplasm

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

cytoskeleton

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

cytosol

cytotoxicity

danegaptide

dermal fibroblasts

detoxification

developmental stage

diabetes

diabetic nephropathy

Hills, Claire, Price, Gareth and Squires, Paul (2017) A role for ATP in tubular fibrosis in the diabetic kidney. In: Diabetes AGM, 08/03/2017 - 10/03/2017, Manchester.

Squires, Paul, Price, Gareth and Hills, Claire (2016) Connexins, hemi-channels and ATP release in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

diabetic retinopathy

dietary intake

dietary-crocin

differentiation

dimerisation

Fili, N, Calleja, V, Woscholski, R, Parker, P J and Larijani, B (2006) Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting. Proceedings of the National Academy of Sciences of the United States of America, 103 (42). pp. 15473-8. ISSN 1091-6490

double-strand breaks

drug derivative

drug effect

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

drug effects

drug potentiation

efaroxan

egg

electrophysiology

embryo

embryo development

endoplasmic reticulum stress

endosomal compartment

endothelium cell

environmental temperature

enzyme activity

enzyme assay

enzyme induction

enzyme inhibition

epididymis fat

epithelium

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

eukaryote

eukaryotic flagellum

evolutionary biology

exposure

extracellular calcium

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

extracellular matrix

female

fertilization

fertilization (reproduction)

fibroblast growth factor

fibroblast growth factor 1

fibroblasts

fibrosis

Hills, Claire, Price, Gareth and Squires, Paul (2017) A role for ATP in tubular fibrosis in the diabetic kidney. In: Diabetes AGM, 08/03/2017 - 10/03/2017, Manchester.

filamentous fungi

flagellum

flavonoid

fluorometry

food intake

fura 2

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

gap-junctions

gastrin release

gastrin, article

gene expression

gene expression regulation

gene sequence

gene transcription

genetics

genome maintenance

genome stability

genome-wide siRNA screen

genomic instability

Ray, Swagat, Chakrabarty, Sanjiban and Chaudhuri, Arnab Ray (2023) Editorial: Impact of genome instability on human health. Frontiers in Molecular Biosciences, 10 . ISSN 2296-889X

glucose

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

glucose blood level

glucose homeostasis

glucose tolerance

glucose transport

glucose transporter 1

glucose transporter 4

glucuronosyltransferase

glutathione transferase

glycemic control

glycerol 3 phosphate dehydrogenase

gm1

Sanghera, Narinder, Correia, Bruno E.F.S., Correia, Joana R.S., Ludwig, Christian, Agarwal, Sonya, Nakamura, Hironori K., Kuwata, Kazuo, Samain, Eric, Gill, Andrew, Bonev, Boyan B. and Pinheiro, Teresa J.T. (2011) Deciphering the Molecular Details for the Binding of the Prion Protein to Main Ganglioside GM1 of Neuronal Membranes. Chemistry & Biology, 18 (11). pp. 1422-1431. ISSN 1074-5521

granulosa cell

hPTECs

heme oxygenase 1

hemi-channels

hemichannel

Squires, Paul, Price, Gareth and Hills, Claire (2016) Connexins, hemi-channels and ATP release in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

hemichannels

histology

homologous recombination

hormone determination

human

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

human cell

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

hydrolysis

hyperglycemia

hypothesis

idazoxan

imaging

Fili, Natalia (2014) Single-molecule and single-particle imaging of molecular motors in vitro and in vivo. In: Fluorescent Methods for Molecular Motors. Springer Nature, pp. 131-59. ISBN 9783034808569

imidazoline

immune response

immune system

immunoblotting

immunoepidemiology

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

immunogenicity

immunoglobulin enhancer binding protein

immunology

immunoprecipitation

immunosuppression

in vitro study

in vitro test

in vivo test

inflamasome

inflammasome

inflammation

influenza A virus

insulin

insulin release

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

insulin resistance

insulin sensitivity

insulin synthesis

intercellular adhesion molecule 1

interleukin 22

interleukin 23

interleukin 24

interleukin 33

interleukin 6

interleukin derivative

interleukin-22

interleukin-24

interleukin-33, mouse, animal cell

interscapular brown adipose tissue

interstitial collagenase

intracellular membrane

invasion

isothiocyanic acid

isotope labeling

karyopherin b2

keratinocyte

kidney

Hills, Claire, Siamantouras, Eleftherios and Squires, Paul (2021) Cell adhesion in renal tubular epithelial cells: Biochemistry, biophysics or both. BIOCELL, 46 (4). pp. 937-940. ISSN 0327-9545

kidney disease

kinetics

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

laser

linear system

lipid composition

lipid raft

lipid storage

liver cell

lymphocyte transformation assay

male

mass spectrometer

mechanical measurements

Dos Santos, Ália, Fili, Natalia, Pearson, David S., Hari-Gupta, Yukti and Toseland, Christopher P. (2021) High-throughput mechanobiology: Force modulation of ensemble biochemical and cell-based assays. Biophysical Journal, 120 (4). pp. 631-641. ISSN 1542-0086

mechanobiology

melanin

membrane biophysics

membrane dynamics

mesenchymal stem cell (MSC)

mesnchymal stem cell

mesnchymal stem cells

messenger RNA

metabolism

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

metastasis

microarray

microfluorometry

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

microplate reader assay

mineralization

mitochondrial biogenesis

mitogen activated protein kinase

mitogen activated protein kinase 1

mitogen activated protein kinase 3

mixed lymphocyte reaction

molecular cloning

Kannangara, Nilu Kumari Wansadhipathi (2011) Sphingolipid synthases of toxoplasma gondii and other organisms. PhD thesis, University of Durham.

molecular evolution

molecular motors

monocyte chemotactic protein 1

monomerisation

mouse

mtDNA replication

mucin O-glycosylation

mucus

mutation

myosin VI

myosins

nanomedicine

nerve cell culture

nerve cell differentiation

nerve fiber growth

nervous system

nervous system development

non insulin dependent diabetes mellitus

nonhuman

nuclear transfer

nuclear transport

nucleotide sequence

nylon 6 6

nylon 66

obesity

orlistat

oscillation

osmolarity

osteoblast

osteoblast cells

oxidative stress

pancreas

pancreas cell

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

pancreas islet

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

pancreas islet beta cell

pancreas tumor

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

peptide

pericellular matrix

peroxisome proliferator activated receptor gamma

peroxisome proliferator activated receptor gamma coactivator 1alpha

phentolamine

phorbol ester

phosphorylation

physics

physiological process

physiology

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

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