|Up a level|
Arcella, A. and Carpinelli, G. and Battaglia, G. and D'Onofrio, M. and Santoro, F. and Ngomba, R. T. and Bruno, V. and Casolini, P. and Giangaspero, F. and Nicoletti, F. (2005) Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo. Neuro-Oncology, 7 (3). pp. 236-245. ISSN 1522-8517
Besong, Gilbert and Battaglia, Giuseppe and D'Onofrio, Mara and Di Marco, Roberto and Ngomba, Richard T. and Storto, Marianna and Castiglione, Marzia and Mangano, Katia and Busceti, Carla L. and Nicoletti, Ferdinando R. and Bacon, Kevin and Tusche, Michael and Valenti, Ornella and Conn, Peter Jeffrey and Bruno, Valeria and Nicoletti, Ferdinando (2002) Activation of group III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures. Journal of Neuroscience, 22 (13). pp. 5403-5411. ISSN 0270-6474
Bikbaev, A. and Neyman, S. and Ngomba, Richard and Conn, J. and Nicoletti, F. and Manahan-Vaughan, D. (2008) MGluR5 mediates the interaction between late-LTP, network activity, and learning. PLoS ONE, 3 (5). ISSN 1932-6203
Biswas, Subhajit and Sukla, Soumi and Field, Hugh J. (2014) Helicase-primase inhibitors for herpes simplex virus: looking to the future of non-nucleoside inhibitors for treating herpes virus infections. Future Medicinal Chemistry, 6 (1). pp. 45-55. ISSN 1756-8919
Bombicz, P. and Csöregh, I. and Gruber, Tobias and Weber, E. and Kálmán, A. (2006) Isostructurality of co-crystals of an ester substituted dinitro calixarene host. In: ECM23, 23rd European Crystallographic Meeting, 6-11 August 2006, Leuven (Belgium).
Bombicz, P. and Gruber, Tobias and Fischer, C. and Weber, E. (2012) Tailor made calixarenes. In: Indaba 7 Workshop – Insights from Structure, 2012, Skukuza (South Africa).
Bombicz, P. and Gruber, Tobias and Weber, E. and Kálmán, A. (2009) Supramolecular morphotropy of calixarene inclusion compounds. In: 12th International Seminar on Inclusion Compounds, 4-9 April 2009, Stellenbosch (South Africa).
Catley, Matthew C. and Chivers, Joanna E. and Holden, Neil S. and Barnes, Peter J. and Newton, Robert (2005) Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells. British journal of pharmacology, 145 (1). pp. 114-22. ISSN 0007-1188
Chess-Williams, RG and Grassby, Paul and Culling, W. and Penny, W. and Broadley, K. J. and Sheridan, D. J. (1985) Cardiac postjunctional supersensitivity to β-agonists after chronic chemical sympathectomy with 6-hydroxydopamine. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 329 (2). pp. 162-166. ISSN 0028-1298
Chivers, Joanna E. and Gong, Wei and King, Elizabeth M. and Seybold, Joachim and Mak, Judith C. and Donnelly, Louise E. and Holden, Neil S. and Newton, Robert (2006) Analysis of the dissociated steroid RU24858 does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids. Molecular pharmacology, 70 (6). pp. 2084-2095. ISSN 0026-895X
Cinque, C. and Zuena, A .R. and Casolini, P. and Ngomba, Richard T. and Melchiorri, D. and Maccari, S. and Nicoletti, F. and Di Giorgi Gerevini, V. and Catalani, A. (2003) Reduced activity of hippocampal group-I metabotropic glutamate receptors in learning-prone rats. Neuroscience, 122 (1). pp. 277-284. ISSN 0306-4522
Citraro, R. and Russo, E. and Ngomba, R.T. and Nicoletti, F. and Scicchitano, F. and Whalley, B.J. and Calignano, A. and De Sarro, G. (2013) CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. Epilepsy Research, 106 (1-2). pp. 74-82. ISSN 0920-1211
D'Amore, V. and Santolini, I. and Celli, R. and Lionetto, L. and De Fusco, A. and Simmaco, M. and van Rijn, C. M. and Vieira, E. and Stauffer, S.R. and Conn, P. J. and Bosco, P. and Nicoletti, F. and van Luijtelaar, G. and Ngomba, R. T. (2014) Head-to head comparison of mGlu1 and mGlu5 receptor activation in chronic treatment of absence epilepsy in WAG/Rij rats. Neuropharmacology, 85 . pp. 91-103. ISSN 0028-3908
D'Amore, V. and Santolini, I. and van Rijn, C.M. and Biagioni, F. and Molinaro, G. and Prete, A. and Conn, P.J. and Lindsley, C.W. and Zhou, Y. and Vinson, P.N. and Rodriguez, A.L. and Jones, C.K and Stauffer, S.R. and Nicoletti, F. and van Luijtelaar, G. and Ngomba, R.T. (2013) Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats. Neuropharmacology, 66 . pp. 330-338. ISSN 0028-3908
Eißmann, F. and Kaltofen, J. and Gruber, Tobias and Weber, E. (2006) Fluorogenic calix- and calix¬arenes – Synthesis and conformational behaviour. In: Symposium ChemoChips, 15-16 November 2006, Weimar (Germany).
Fazio, F. and Lionetto, L. and Molinaro, G. and Bertrand, H.O. and Acher, F. and Ngomba, R.T. and Notartomaso, S. and Curini, M. and Rosati, O. and Scarselli, P. and Di Marco, R.a and Battaglia, G. and Bruno, V. and Simmaco, M. and Pin, J.P. and Nicoletti, F. and Goudet, C. (2012) Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors. Molecular Pharmacology, 81 (5). pp. 643-656. ISSN 0026-895X
Granata, Filippo and Potenza, Rossella Luisa and Fiori, Anna and Strom, Roberto and Caronti, Brunella and Molinari, Paola and Donsante, Sonia and Citro, Gennaro and Iacovelli, Luisa and De Blasi, Antonio and Ngomba, Richard T. and Palladini, Guido and Passarelli, Francesca (2003) Expression of OP4 (ORL1, NOP1) receptors in vascular endothelium. European Journal of Pharmacology, 482 (1-3). pp. 17-23. ISSN 0014-2999
Gruber, T. (2010) From enzyme mimics to sensor molecules. In: ., June 2010, Hungarian Academy of Science, Budapest (Hungary.
Gruber, T. (2015) In the molecular cage: complexation of biologically active compounds. In: Invited Lecture hosted by the Institute of Pharmacology and Toxicology, January 2015, University of the German Armed Forces, Munich.
Gruber, T. (2014) Little change, deep impact: solvents and their fundamental influence on crystal formation. In: 65th BHT: Crystallography in Practice, June 2014, Freiberg (Germany).
Gruber, T. (2015) On the way to new shores: caprolactam derivatives as starting point for unprecedented antibiotics. In: Hungarian-German Spring symposium on organic (and) structural chemistry, April 2015, Budapest (Hungary).
Gruber, T. (2011) Sensor active molecules and antibiotics. In: Invited Lecture, January 2011, Hungarian Academy of Science, Budapest (Hungary),.
Gruber, T. (2005) Synthesis, structures and inclusion behaviour of functionalized calixarenes. In: ., October 2005, Department of Natural Sciences, University of Chemnitz (Germany).
Gruber, Tobias (2015) Fluorescophanes: a new generation of fluorescent macrocycles. In: Calix2015, 5-9 July 2015, Giardini Naxos (Italy).
Gruber, Tobias (2013) Without malaria no gin & tonic (with experiments). In: Christmas Lecture 2013, December 2013, University of Freiberg (Germany).
Gruber, Tobias (2014) The chemistry of X-mas. In: JCF Christmas Lecture, December 2014, University of Cologne (Germany).
HAWTHORN, M. H. and CHESSWILLIAMS, R. G. and Grassby, P. F. and BROADLEY, K. J. (1985) The use of forskolin to investigate the site of cardiac beta-adrenoreceptor supersensitivity. Journal of Autonomic Pharmacology, 5 (3). pp. 231-239. ISSN 0144-1795
Holden, Neil S. and Gong, W. and King, E. M. and Kaur, M. and Giembycz, M. A. and Newton, R. (2007) Potentiation of NF-κB-dependent transcription and inflammatory mediator release by histamine in human airway epithelial cells. British journal of pharmacology, 152 (6). pp. 891-902. ISSN 0007-1188
Holden, Neil S. and Rider, C. F. and Bell, M. J. and Velayudhan, J. and King, E. M. and Kaur, M. and Salmon, M. and Giembycz, M. A. and Newton, R. (2010) Enhancement of inflammatory mediator release by beta(2)-adrenoceptor agonists in airway epithelial cells is reversed by glucocorticoid action. British journal of pharmacology, 160 (2). pp. 410-420. ISSN 0007-1188
Kelly, M. M. and King, E. M. and Rider, C. F. and Gwozd, C. and Holden, Neil S. and Eddleston, J. and Zuraw, B. and Leigh, R. and O'Byrne, P. M. and Newton, R. (2012) Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide. British Journal of Pharmacology, 165 (6). pp. 1737-1747. ISSN 0007-1188
King, Elizabeth M. and Kaur, Manminder and Gong, Wei and Rider, Christopher F. and Holden, Neil S. and Newton, Robert (2009) Regulation of tristetraprolin expression by interleukin-1β and dexamethasone in human pulmonary epithelial cells: Roles for nuclear factor-κB and p38 mitogen-activated protein kinase. The journal of pharmacology and experimental therapeutics, 330 (2). pp. 575-585. ISSN 0022-3565
Klem, B. and Lappin, Graham and Nicholson, S. and Van De Wetering, J. and De Vries, D. E. and Oosterhuis, B. and Garner, R. C. (2006) Determination of the bioavailability of 14C-hexaminolevulinate using accelerator mass spectrometry after intravesical administration to human volunteers. Journal of Clinical Pharmacology, 46 (4). pp. 456-460. ISSN 0091-2700
Kuroda, Satoshi and Katsura, Ken-ichiro and Hillered, Lars and Bates, Timothy E. and Siesjö, Bo K. (1996) Delayed treatment with alpha-phenyl-N-tert-butyl nitrone (PBN) attenuates secondary mitochondrial dysfunction after transient focal cerebral ischemia in the rat. Neurobiology of Disease, 3 (2). pp. 149-157. ISSN 0969-9961
Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027
Lappin, Graham and Kuhnz, Wilhelm and Jochemsen, Roeline and Kneer, Johannes and Chaudhary, Ajai and Oosterhuis, Berend and Drijfhout, Willem Jan and Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236
Manahan-Vaughan, D. and Ngomba, Richard T. and Storto, M. and Kulla, A. and Catania, M. V. and Chiechio, S. and Rampello, L. and Passarelli, F. and Capece, A. and Reymann, K. G. and Nicoletti, F. (2003) An increased expression of the mGlu5 receptor protein following LTP induction at the perforant path-dentate gyrus synapse in freely moving rats. Neuropharmacology, 44 (1). pp. 17-25. ISSN 0028-3908
Marrocco, J. and Mairesse, J. and Ngomba, R.T. and Silletti, V. and Van Camp, G. and Bouwalerh, H. and Summa, M. and Pittaluga, A. and Nicoletti, F. and Maccari, S. and Morley-Fletcher, S. (2012) Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 32 (48). pp. 17143-17154. ISSN 0270-6474
Matrisciano, F. and Scaccianoce, S. and Del Bianco, P. and Panaccione, I. and Canudas, A. M. and Battaglia, G. and Riozzi, B. and Ngomba, R. T. and Molinaro, G. and Tatarelli, R. and Melchiorri, D. and Nicoletti, F. (2005) Metabotropic glutamate receptors and neuroadaptation to antidepressants: imipramine-induced down-regulation of β-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands. Journal of Neurochemistry, 93 (5). pp. 1345-1352. ISSN 0022-3042
Matrisciano, F. and Storto, M. and Ngomba, Richard T. and Cappuccio, I. and Caricasole, A. and Scaccianoce, S. and Riozzi, B. and Melchiorri, D. and Nicoletti, F. (2002) Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus. Neuropharmacology, 42 (8). pp. 1008-1015. ISSN 0028-3908
Moyanova, S. G. and Mastroiacovo, F. and Kortenska, L. V. and Mitreva, R. G. and Fardone, E. and Santolini, I. and Sobrado, M. and Battaglia, G. and Bruno, V. and Nicoletti, F. and Ngomba, R. T. (2011) Protective role for type 4 metabotropic glutamate receptors against ischemic brain damage. Journal of Cerebral Blood Flow and Metabolism, 31 (4). pp. 1107-1118. ISSN 0271-678X
Moyanova, S. G. and Mitreva, R. G. and Kortenska, L. V. and Nicoletti, F. and Ngomba, R.T. (2013) Age-dependence of sensorimotor and cerebral electroencephalographic asymmetry in rats subjected to unilateral cerebrovascular stroke. Experimental and Translational Stroke Medicine, 5 (1). ISSN 2040-7378
Moyanova, S.G. and Kortenska, L.V. and Mitreva, R.G. and Pashova, V.D. and Ngomba, R.T. and Nicoletti, F. (2007) Multimodal assessment of neuroprotection applied to the use of MK-801 in the endothelin-1 model of transient focal brain ischemia. Brain Research, 1153 (1). pp. 58-67. ISSN 0006-8993
Newton, Robert and Holden, Neil S. (2007) Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor? Molecular pharmacology, 72 (4). pp. 799-809. ISSN 0026-895X
Newton, Robert and Holden, Neil S. and Catley, Matthew C. and Oyelusi, Wale and Leigh, Richard and Proud, David and Barnes, Peter J. (2007) Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IκB kinase inhibitors. The journal of pharmacology and experimental therapeutics, 321 (2). pp. 734-42. ISSN 0022-3565
Ngomba, R. T. and Biagioni, F. and Casciato, S. and Willems-Van Bree, E. and Battaglia, G. and Bruno, V. and Nicoletti, F. and Van Luijtelaar, E. L. J. M. (2005) The preferential mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy. Neuropharmacology, 49 (SUPPL.). pp. 89-103. ISSN 0028-3908
Ngomba, R. T. and Santolini, I. and Biagioni, F. and Molinaro, G. and Simonyi, A. and Van Rijn, C. M. and D'Amore, V. and Mastroiacovo, F. and Olivieri, G. and Gradini, R. and Ferraguti, F. and Battaglia, G. and Bruno, V. and Puliti, A. and Van Luijtelaar, G. and Nicoletti, F. (2011) Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy. Neuropharmacology, 60 (7-8). pp. 1281-1291. ISSN 0028-3908
Ngomba, Richard T. and Ferraguti, F. and Badura, A. and Citraro, R. and Santolini, I. and Battaglia, G. and Bruno, V. and De Sarro, G. and Simonyi, A. and van Luijtelaar, G. and Nicoletti, F. (2008) Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures. Neuropharmacology, 54 (2). pp. 344-354. ISSN 0028-3908
Ngomba, Richard Teke and Santolini, I. and Salt, T. E. and Ferraguti, F. and Battaglia, G. and Nicoletti, F. and Van Luijtelaar, G. (2011) Metabotropic glutamate receptors in the thalamocortical network: strategic targets for the treatment of absence epilepsy. Epilepsia, 52 (7). pp. 1211-1222. ISSN 0013-9580
Nicoletti, F. and Battaglia, G. and Storto, M. and Ngomba, Richard T. and Iacovelli, L. and Arcella, A. and Gradini, R. and Sale, P. and Rampello, L. and De Vita, T. and Di Marco, R. and Melchiorri, D. and Bruno, V. (2007) Metabotropic glutamate receptors: Beyond the regulation of synaptic transmission. Psychoneuroendocrinology, 32 (Supp 1). S40-S45. ISSN 0306-4530
Nicoletti, F. and Bruno, V. and Ngomba, R. T and Gradini, R. and Battaglia, G. (2015) Metabotropic glutamate receptors as drug targets: what's new? Current Opinion in Pharmacology, 20 . pp. 89-94. ISSN 14714892
Rider, Christopher F. and King, Elizabeth M. and Holden, Neil S. and Giembycz, Mark A. and Newton, Robert (2011) Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting beta2-adrenoceptor agonists. Journal of Pharmacology and Experimental Therapeutics, 338 (3). pp. 860-869. ISSN 0022-3565
Rumsey, R. D. E. and Squires, Paul and Read, N. W. (1993) In vitro effects of sennoside on contractile activity and fluid flow in the perfused large intestine of the rat. Pharmacology, 47 (SUP 1). pp. 32-39. ISSN 0031-7012
Schulze, M. and Gruber, Tobias and Weber, E. and Pollex, R. and Mazik, M. (2014) Design, synthesis and complexation studies of new indium ligands: calixarenes as ligands. In: Akita Summer Camp, 2014, Holzhau (Germany).
Shepherd, R. M. and Hashmi, M. N. and Kane, C. and Squires, Paul and Dunne, M. J. (1996) Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: Implications for stimulus-response coupling of insulin release. British Journal of Pharmacology, 119 (5). pp. 911-916. ISSN 0007-1188
Simonyi, Agnes and Ngomba, Richard T. and Storto, Marianna and Catania, Maria V. and Miller, Laura A. and Youngs, Brian and DiGorgi-Gerevini, Valeria and Nicoletti, Ferdinando and Sun, Grace Y. (2005) Expression of groups I and II metabotropic glutamate receptors in the rat brain during aging. Brain Research, 1043 (1-2). pp. 95-106. ISSN 0006-8993
Siriwardena, A. Niroshan and Middlemass, Jo B. and Ward, Kate and Wilkinson, Carol (2009) Drivers for change in primary care of diabetes following a protected learning time educational event: interview study of practitioners. BMC Medical Education, 8 (4). pp. 1-9. ISSN 1472-6920
Storto, Marianna and Ngomba, Richard T. and Battaglia, Giuseppe and Freitas, Isabel and Griffini, Patrizia and Richelmi, Plinio and Nicoletti, Ferdinando and Vairetti, Mariapia (2003) Selective blockade of mGlu5 metabotropic glutamate receptors is protective against acetaminophen hepatotoxicity in mice. Journal of Hepatology, 38 (2). pp. 179-187. ISSN 0168-8278
Van Rijn, C. M. and Gaetani, S. and Santolini, I. and Badura, A. and Gabova, A. and Fu, J. and Watanabe, M. and Cuomo, V. and Van Luijtelaar, G. and Nicoletti, F. and Ngomba, R. T. (2010) WAGRij rats show a reduced expression of CB1 receptors in thalamic nuclei and respond to the CB1 receptor agonist, R(+)WIN55,212-2, with a reduced incidence of spike-wave discharges. Epilepsia, 51 (8). pp. 1511-1521. ISSN 0013-9580