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Items where Subject is "B Subjects allied to Medicine > B200 Pharmacology, Toxicology and Pharmacy"

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Abdel-Razaq, W. and Bates, T. E. and Kendall, D. A. (2007) The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system. Biochemical Pharmacology, 73 (12). pp. 1995-2003. ISSN 0006-2952

Algay, Virginie and Singh, Ishwar and Heaney, Frances (2010) Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition. Organic and Biomolecular Chemistry, 8 (2). pp. 391-397. ISSN 1477-0520

Ali, Hany S. M. and York, Peter and Blagden, Nicholas (2009) Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors. International Journal of Pharmaceutics, 375 (1-2). pp. 107-113. ISSN 0378-5173

Allen, Kathryn L. and Almeida, Angeles and Bates, Timothy E. and Clark, John B. (1995) Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. Journal of neurochemistry, 64 (5). pp. 2222-2229. ISSN 0022-3042

Almeida, A. and Brooks, K. J. and Sammut, I. and Keelan, J. and Davey, G. P. and Clark, J. B. and Bates, T. E. (1995) Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Developmental Neuroscience, 17 (4). pp. 212-218. ISSN 0378-5866

Almeida, Angeles and Allen, Kathryn L. and Bates, TImothy E. and Clark, John B. (1995) Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. Journal of neurochemistry, 65 (4). pp. 1698-1703. ISSN 0022-3042

Alnahar, Saja and Elliott, Rachel A. and Smith, Murray D. (2018) Biosimilar uptake by British local formularies: a cross sectional study. International Journal of Clinical Pharmacy . ISSN 2210-7703

Amani, Amir and Ali, Hany and Blagden, Nicholas and York, Peter (2014) Evaluation of a nanodispersion formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers. Iranian Journal of Pharmaceutical Research, 13 (3). pp. 785-796. ISSN 1735-0328

Athanasiou, Andriani and Clarke, Anna B. and Turner, Amy E. and Kumaran, Nethia M. and Vakilpour, Sara and Smith, Paul A. and Bagiokou, Dimitra and Bradshaw, Tracey D. and Westwell, Andrew D. and Fang, Lin and Lobo, Dileep N. and Constantinescu, Cris S. and Calabrese, Vittorio and Loesch, Andrzej and Alexander, Stephen P. H. and Clothier, Richard H. and Kendall, David A. and Bates, Timothy E. (2007) Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications, 364 (1). pp. 131-137. ISSN 0006-291x

Athanasiou, Andriani and Smith, Paul A. and Vakilpour, Sara and Kumaran, Nethia M. and Turner, Amy E. and Bagiokou, Dimitra and Layfield, Robert and Ray, David E. and Westwell, Andrew D. and Alexander, Stephen P. H. and Kendall, David A. and Lobo, Dileep N. and Watson, Susan A. and Lophatanon, Artitaya and Muir, Kenneth A. and Guo, De-An and Bates, Timothy E. (2007) Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications, 354 (1). pp. 50-55. ISSN 0006-291X

Bannunah, Azzah M. and Vllasaliu, Driton and Lord, Jennie and Stolnik, Snjezana (2014) The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11 (12). pp. 4363-4373. ISSN 1543-8384

Barlow, A. D. and Xie, J. and Moore, C. E. and Campbell, S. C. and Shaw, J. A. M. and Nicholson, M. L. and Herbert, T. P. (2012) Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). Diabetologia, 55 (5). pp. 1355-1365. ISSN 0012-186X

Baron, M. G. and Elie, M. (2003) Temperature sensing using reversible thermochromic polymeric films. Sensors and Actuators, B: Chemical, 90 (1-3). pp. 271-275. ISSN 0925-4005

Baron, M. G. and Narayanaswamy, R. and Thorpe, S. C. (1996) Hydrophobic membrane sensors for the optical determination of hydrogen chloride gas. Sensors and Actuators, B: Chemical, 34 (1-3). pp. 511-515. ISSN 0925-4005

Bates, T E and Almeida, A and Heales, S J and Clark, J B (1994) Postnatal development of the complexes of the electron transport chain in isolated rat brain mitochondria. Developmental neuroscience, 16 (5-6). pp. 321-7. ISSN 0378-5866

Bates, T. E and Loesch, A. and Burnstock, G. and Clark, J. B. (1995) Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver. Biochemical and biophysical research communications, 213 (3). pp. 896-900. ISSN 0006-291X

Bates, T. E. and Heales, S. J. and Davies, S. E. and Boakye, P. and Clark, J. B. (1994) Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. Journal of neurochemistry, 63 (2). pp. 640-648. ISSN 0022-3042

Bates, T. E. and Loesch, A. and Burnstock, G. and Clark, J. B. (1996) Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation? Biochemical and biophysical research communications, 218 (1). pp. 40-44. ISSN 0006-291X

Bates, T. E. and Williams, S. R. and Busza, A. L. and Gadian, D. G. and Proctor, E. (1988) A 31P nuclear magnetic resonance study in vivo of metabolic abnormalities in rats with acute liver failure. NMR in biomedicine, 1 (2). pp. 67-73. ISSN 0952-3480

Bates, Timothy E. and Williams, Stephen R. and Gadian, David G. (1989) Phosphodiesters in the liver: the effect of field strength on the 31P signal. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 12 (1). pp. 145-150. ISSN 0740-3194

Bates, Timothy E. and Williams, Stephen R. and Kauppinen, Risto A. and Gadian, David G. (1989) Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of neurochemistry, 53 (1). pp. 102-10. ISSN 0022-3042

Belokon, Yuri N. and Kochetkov, Konstantin A. and Churkina, Tatiana D. and Ikonnikov, Nikolai S. and Chesnokov, Alexey A. and Larionov, Oleg V. and Singh, Ishwar and Parmar, Virinder S. and Vyskocil, Stepan and Kagan, Henri B. (2000) Asymmetric PTC C-alkylation catalyzed by chiral derivatives of tartaric acid and aminophenols. Synthesis of (R)- and (S)-alpha-methyl amino acids. Journal of Organic Chemistry, 65 (21). pp. 7041-7048. ISSN 0022-3263

Bethge, Lucas and Singh, Ishwar and Seitz, Oliver (2010) Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization. Organic and Biomolecular Chemistry, 8 (10). pp. 2439-2448. ISSN 1477-0520

Beuck, C and Singh, I. and Bhattacharya, A and Heckler, W and Parmar, VS and Seitz, O and Weinhold, E (2003) Polycyclic aromatic DNA-Base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angewandte Chemie International Edition, 42 (33). pp. 3958-3960. ISSN 1433-7851

Blagden, N. and Davey, R. J. and Rowe, R. and Roberts, R. (1998) Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole. International Journal of Pharmaceutics, 172 (1-2). pp. 169-177. ISSN 0378-5173

Blagden, N. and de Matas, M. and Gavan, P.T. and York, P. (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews, 59 (7). pp. 617-630. ISSN 0169-409X

Blagden, Nicholas (2001) Crystal engineering of polymorph appearance: the case of sulphathiazole. Powder Technology, 121 (1). pp. 46-52. ISSN 0032-5910

Blagden, Nicholas and Cross, Wendy I. and Davey, Roger J. and Broderick, Mairead and Pritchard, Robin G. and Roberts, Ronald J. and Rowe, Raymond C. (2001) Can crystal structure prediction be used as part of an integrated strategy for ensuring maximum diversity of isolated crystal forms? The case of 2-amino-4-nitrophenol. Physical Chemistry Chemical Physics, 3 (17). pp. 3819-3825. ISSN 1463-9076

Blagden, Nicholas and Davey, R. (1999) Polymorphs take shape. Chemistry in Britain, 35 (3). pp. 44-45. ISSN 0009-3106

Bridle, C. and Palmer, S. and Bagnall, A.-M. and Darba, J. and Duffy, S. and Sculpher, M. and Riemsma, R. (2004) A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder. Health Technology Assessment, 8 (19). iii-109. ISSN 1366-5278

Broadley, K. J. and Chess-Williams, R. G. and Grassby, P. F. (1986) A physiological basis for subclassifying beta-adrenoceptors examined by chemical sympathectomy of guinea-pigs. Journal of Physiology, 373 (1). pp. 367-378. ISSN 0022-3751

Broadley, K. J. and Williams, R. G. and Hawthorn, M. H. and Grassby, Paul (1984) Mechanisms of cardiac supersensitivity to sympathomimetic amines. Methods and Findings in Experimental and Clinical Pharmacology, 6 (4). pp. 179-186. ISSN 0379-0355

Broadley, Kenneth J. and Grassby, Paul F. (1985) Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition. Naunyn-Schmiedeberg's Archives of Pharmacology, 331 (4). pp. 316-323. ISSN 0028-1298

Brooks, K. J. and Kauppinen, R. A. and Williams, S. R. and Bachelard, H. S. and Bates, T. E. and Gadian, D. G. (1989) Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience, 33 (1). pp. 185-192. ISSN 0306-4522

Brooks, Keith J. and Hargreaves, Iain P. and Bates, Timothy E. (2008) Protection of respiratory chain enzymes from ischaemic damage in adult rat brain slices. Neurochemical research, 33 (9). pp. 1711-1716. ISSN 0364-3190

Burt, T. and Yoshida, K. and Lappin, G. and Vuong, L. and John, C. and de Wildt, S. N. and Sugiyama, Y. and Rowland, M. (2016) Microdosing and other phase 0 clinical trials: facilitating translation in Drug Development. Clinical and Translational Science, 9 (2). pp. 74-88. ISSN 1752-8054

Calabrese, Vittorio and Bates, Timothy E. and Mancuso, Cesare and Cornelius, Carolin and Ventimiglia, Bernardo and Cambria, Maria Teresa and Di Renzo, Laura and De Lorenzo, Antonino and Dinkova-Kostova, Albena T. (2008) Curcumin and the cellular stress response in free radical-related diseases. Molecular Nutrition & Food Research, 52 (9). pp. 1062-1073. ISSN 1613-4125

Calabrese, Vittorio and Cornelius, Carolin and Mancuso, Cesare and Pennisi, Giovanni and Calafato, Stella and Bellia, Francesco and Bates, Timothy E. and Giuffrida Stella, Anna Maria and Schapira, Tony and Dinkova Kostova, Albena T. and Rizzarelli, Enrico (2008) Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochemical Research, 33 (12). pp. 2444-2471. ISSN 0364-3190

Capel, Victoria and Vllasaliu, Driton and Watts, Peter and Stolnik, Snow (2016) Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency. Biochemical and Biophysical Research Communications, 477 (2). pp. 260-265. ISSN 0006-291X

Casettari, Luca and Vllasaliu, Driton and Castagnino, Enzo and Stolnik, Snjezana and Howdle, Steven and Illum, Lisbeth (2012) PEGylated chitosan derivatives: synthesis, characterizations and pharmaceutical applications. Progress in Polymer Science, 37 (5). pp. 659-685. ISSN 0079-6700

Casettari, Luca and Vllasaliu, Driton and Lam, Jenny K. W. and Soliman, Mahmoud and Illum, Lisbeth (2012) Biomedical applications of amino acid-modified chitosans: a review. Biomaterials, 33 (30). pp. 7565-7583. ISSN 0142-9612

Casettari, Luca and Vllasaliu, Driton and Mantovani, Guiseppe and Howdle, Steven M. and Stolnik, Snow and Illum, Lisbeth (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules, 11 (11). pp. 2854-2865. ISSN 1525-7797

Chan, S. M. H. and Zhao, X. and Elfowiris, A. and Ratnam, C. and Herbert, T. P. (2017) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells. Biochimie, 138 . pp. 156-167. ISSN 0300-9084

Daci, Armond and Beretta, Giangiacomo and Vllasaliu, Driton and Shala, Aida and Govori, Valbona and Norata, Giuseppe and Krasniqi, Shaip (2015) Polymorphic variants of SCN1A and EPHX1 influence plasma carbamazepine concentration, metabolism and pharmacoresistance in a population of Kosovar Albanian epileptic patients. PLOS ONE . ISSN 1932-6203

Daley, E. and Wilkie, D. and Loesch, A. and Hargreaves, I. P. and Kendall, D. A. and Pilkington, G. J. and Bates, T. E. (2005) Chlorimipramine: a novel anticancer agent with a mitochondrial target. Biochemical and Biophysical Research Communications, 328 (2). pp. 623-632. ISSN 0006-291X

Davey, R. J. and Blagden, N. (1999) Computational approaches to crystal engineering. Journal of Pharmacy and Pharmacology, 51 (SUPPL.). p. 2. ISSN 0022-3573

Davey, R. J. and Blagden, N. and Potts, G. D. and Docherty, R. (1997) Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. Journal of the American Chemical Society, 119 (7). pp. 1767-1772. ISSN 0002-7863

Davey, R. J. and Blagden, N. and Righini, S. and Alison, H. and Ferrari, E. S. (2002) Nucleation control in solution mediated polymorphic phase transformations: the case of 2,6-dihydroxybenzoic acid. Journal of Physical Chemistry B, 106 (8). pp. 1954-1959. ISSN 1520-6106

David, W. I. F. and Shankland, K. and Pulham, C. R. and Blagden, N. and Davey, R. J. and Song, M. (2005) Polymorphism in benzamide. Angewandte Chemie - International Edition, 44 (43). pp. 7032-7035. ISSN 1433-7851

Davis, Carol and Carberry, Stephen and Schrettl, Markus and Singh, Ishwar and Stephens, John C. and Barry, Sarah M. and Kavanagh, Kevin and Challis, Gregory L. and Brougham, Dermot and Doyle, Sean (2011) The role of glutathione S-Transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 18 (4). pp. 542-552. ISSN 1074-5521

Davis, Carol and Gordon, Natasha and Murphy, Sinead and Singh, Ishwar and Kavanagh, Kevin and Carberry, Stephen and Doyle, Sean (2011) Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry. Analytical and Bioanalytical Chemistry, 401 (8). pp. 2519-2529. ISSN 1618-2642

Dematos, Luciana L. and Williams, Adrian C. and Booth, Steven W. and Petts, Catherine R. and Taylor, David J. and Blagden, Nicholas (2007) Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry. Journal of Pharmaceutical Sciences, 96 (5). pp. 1069-1078. ISSN 0022-3549

Elie, Leonie and Elie, Mathieu and Cave, Gareth and Vetter, Marleen and Croxton, Ruth and Baron, Mark (2016) Microcrystalline testing used in combination with Raman micro-spectroscopy for absolute identification of novel psychoactive substances. Journal of Raman Spectroscopy, 47 (11). pp. 1343-1350. ISSN 0377-0486

Elie, Mathieu P. and Elie, Leonie E. and Baron, Mark G. (2013) Keeping pace with NPS releases: fast GC-MS screening of legal high products. Drug Testing and Analysis, 5 (5). pp. 281-290. ISSN 1942-7603

Elie, Mathieu Pierre and Baron, Mark G. and Birkett, Jason W. (2012) Injection port silylation of γ-hydroxybutyrate and trans-hydroxycrotonic acid: Conditions optimisation and characterisation of the di-tert-butyldimethylsilyl derivatives by GC-MS. Analyst, 137 (1). p. 255. ISSN 0003-2654

Errington, W. and Parmar, V. S. and Singh, A. and Singh, I. (2001) 7-acetoxy-4-(1-chloroethyl)coumarin. Acta Crystallographica Section E - Structure Reports Online, 57 (10). O939-O940. ISSN 1600-5368

Field, Hugh J. and Biswas, Subhajit and Mohammad, Islam T. (2006) Herpesvirus latency and therapy--from a veterinary perspective. Antiviral Research, 71 (2-3). pp. 127-133. ISSN 0166-3542

Gadian, D. G. and Bates, T. E. and Williams, S. R. and Bell, J. D. and Austin, S. J. and Connelly, A. (1991) Approaches to editing, assignment and interpretation of proton spectra. NMR in biomedicine, 4 (2). pp. 85-89. ISSN 0952-3480

Garnett, Martin and Vllasaliu, Driton and Stolnik, Snow and Falcone, Franco (2014) Drug delivery: epithelial cell models for drug transport and toxicology studies. The Biochemist, 36 (3). p. 8. ISSN 0954-982X

Golding, C. V. P. and Danchaivijitr, C. and Hodgson, T. L. and Tabrizi, S. J. and Kennard, C. (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology, 67 (3). pp. 485-487. ISSN 0028-3878

Hainke, Sven and Singh, Ishwar and Hemmings, Jennifer and Seitz, Oliver (2007) Synthesis of C-aryl-nucleosides and O-aryl-glycosides via cuprate glycosylation. Journal of Organic Chemistry, 72 (23). pp. 8811-8819. ISSN 0022-3263

Harris, Frederick and Prabhu, Saurabh and R. Dennison, Sarah and J. Snape, Timothy and Lea, Robert and Mura, Manuela and A. Phoenix, David (2016) Anionic host defence peptides from the plant kingdom: their anticancer activity and mechanisms of action. Protein & Peptide Letters, 23 (8). pp. 676-687. ISSN 0929-8665

Heales, S. J. and Davies, S. E. and Bates, T. E. and Clark, J. B. (1995) Depletion of brain glutathione is accompanied by impaired mitochondrial function and decreased N-acetyl aspartate concentration. Neurochemical research, 20 (1). pp. 31-38. ISSN 0364-3190

Kirkham, Emma and Bazire, Stephen and Anderson, Timothy and Wood, John and Grassby, Paul and Desborough, James (2013) Impact of active monitoring on lithium management in Norfolk. Therapeutic Advances in Psychopharmacology, 3 (5). pp. 260-265. ISSN 2045-1253

Kohler, O. and Jarikote, D. V. and Singh, I. and Parmar, V. S. and Weinhold, E. and Seitz, O. (2005) Forced intercalation as a tool in gene diagnostics and in studying DNA-protein interactions. Pure and Applied Chemistry , 77 (1). pp. 327-338. ISSN 0033-4545

Krpetic, Zeljka and Singh, Ishwar and Su, Wu and Guerrini, Luca and Faulds, Karen and Burley, Glenn A. and Graham, Duncan (2012) Directed assembly of DNA-functionalized gold nanoparticles using pyrrole-imidazole polyamides. Journal of the American Chemical Society, 134 (20). pp. 8356-8359. ISSN 0002-7863

Kulkarni, Chaitrali and Wood, Clive and Kelly, Adrian L. and Gough, Tim and Blagden, Nicholas and Paradkar, Anant (2015) Stoichiometric control of co-crystal formation by solvent free continuous co-crystallization (SFCC). Crystal Growth & Design, 15 (12). pp. 5648-5651. ISSN 1528-7483

Kumar, Ajay and Husain, Mofazzal and Prasad, Ashok K. and Singh, Iswar and Vats, Archana and Sharma, Nawal K. and Sharma, Sunil K. and Gupta, Rajinder K. and Olsen, Carl E. and Bracke, Marc E. and Gross, Richard A. and Parmar, Virinder S. (2003) Synthesis of novel heterocyclic compounds: routes to pyrazolyl 1,2,3-triazoles and their biological activity evaluation. Indian Journal of Chemistry : Section B, Oganic Chemistry including Medicinal Chemistry, 42 (8). pp. 1950-1957. ISSN 0376-4699

Lappin, G. and Boyce, M. J. and Matzow, T. and Lociuro, S. and Seymour, M. and Warrington, S. J. (2013) A microdose study of 14C-AR-709 in healthy men: pharmacokinetics, absolute bioavailability and concentrations in key compartments of the lung. European Journal of Clinical Pharmacology, 69 (9). pp. 1673-1682. ISSN 0031-6970

Lappin, Graham (2016) Approaches to intravenous clinical pharmacokinetics: recent developments with isotopic microtracers. The Journal of Clinical Pharmacology, 56 (1). pp. 11-23. ISSN 0091-2700

Lappin, Graham (2015) The expanding utility of microdosing. Clinical Pharmacology in Drug Development, 4 (6). pp. 401-406. ISSN 2160-763X

Lappin, Graham and Garner, R. Colin (2004) Current perspectives of 14C-isotope measurement in biomedical accelerator mass spectrometry. Analytical and Bioanalytical Chemistry, 378 (2). pp. 356-364. ISSN 1618-2642

Lappin, Graham and Garner, R. Colin (2006) A review of human phase 0 (microdosing) clinical trials following the US food and drug administration exploratory investigational new drug studies guidance. International Journal of Pharmaceutical Medicine, 20 (3). pp. 159-165. ISSN 1364-9027

Lappin, Graham and Kuhnz, Wilhelm and Jochemsen, Roeline and Kneer, Johannes and Chaudhary, Ajai and Oosterhuis, Berend and Drijfhout, Willem Jan and Rowland, Malcolm and Garner, R. Colin (2006) Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs. Clinical Pharmacology and Therapeutics, 80 (3). pp. 203-215. ISSN 0009-9236

Lappin, Graham and Noveck, Robert and Burt, Tal (2013) Microdosing and drug development: past, present and future. Expert Opinion on Drug Metabolism and Toxicology, 9 (7). pp. 817-834. ISSN 1742-5255

Lucarini, Simone and Fagioli, Laura and Campana, Raffaella and Cole, Hannah and Duranti, Andrea and Baffone, Wally and Vllasaliu, Driton and Casettari, Luca (2016) Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity. European Journal of Pharmaceutics and Biopharmaceutics, 107 . pp. 88-96. ISSN 0939-6411

Madan, Babita and Singh, Ishwar and Kumar, Ajit and Prasad, Ashok K. and Raj, Hanumantharao G. and Parmar, Virinder S. and Ghosh, Balaram (2002) Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs). Bioorganic and Medicinal Chemistry, 10 (11). pp. 3431-3436. ISSN 0968-0896

Mancuso, Cesare and Bates, Timothy E. and Butterfield, D. Allan and Calafato, Stella and Cornelius, Carolin and De Lorenzo, Antonino and Dinkova Kostova, Albena T. and Calabrese, Vittorio (2007) Natural antioxidants in Alzheimer's disease. Expert Opinion on Investigational Drugs, 16 (12). pp. 1921-1931. ISSN 1354-3784

McLeod, H. L. and Brunton, V. G. and Eckardt, N. and Lear, M. J. and Robins, D. J. and Workman, P. and Graham, M. A. (1996) In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022. British Journal of Cancer, 74 (11). pp. 1714-1718. ISSN 0007-0920

Moradi, Emilia and Vllasaliu, Driton and Garnett, Martin and Falcone, Franco and Stolnik, Snow (2012) Ligand density and clustering effects on endocytosis of folate modified nanoparticles. RSC Advances, 2 (7). pp. 3025-3033. ISSN 2046-2069

Murphy, Elizabeth J. and Bates, Timothy E. and Williams, Stephen R. and Watson, Tracey and Brindle, Kevin M. and Rajagopalan, Bheeshma and Radda, George K. (1992) Endoplasmic reticulum: the major contributor to the PDE peak in hepatic 31P-NMR spectra at low magnetic field strengths. Biochimica et biophysica acta: biomembranes, 1111 (1). pp. 51-58. ISSN 0005-2736

Pardon, Marie-Christine and Sarmad, Sarir and Rattray, Ivan and Bates, Timothy E. and Scullion, Gillian A. and Marsden, Charles A. and Barrett, David A. and Lowe, James and Kendall, David A. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging, 30 (7). pp. 1099-1113. ISSN 0197-4580

Parmar, Virinder S. and Sharma, Nawal K. and Husain, Mofazzal and Watterson, Arthur C. and Kumar, Jayant and Samuelson, Lynne A. and Cholli, Ashok L. and Prasad, Ashok K. and Kumar, Ajay and Malhotra, Sanjay and Kumar, Naresh and Jha, Amitabh and Singh, Amarjit and Singh, Ishwar and Himanshu, and Vats, Archana and Shakil, Najam A. and Trikha, Smriti and Mukherjee, Shubasish and Sharma, Sunil K. and Singh, Sanjay K. and Kumar, Ajay and Jha, Hriday N. and Olsen, Carl E. and Stove, Chrisophe P. and Bracke, Marc E. and Mareel, Marc M. (2003) Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds. Bioorganic and Medicinal Chemistry, 11 (6). pp. 913-929. ISSN 0968-0896

Perry, Matthew W. D. and Björhall, Karin and Bonn, Britta K. and Carlsson, Johan and Chen, Yunhua and Eriksson, Anders and Fredlund, Linda and Hao, Hai'e and Holden, Neil S. and Karabelas, Kostas and Lindmark, Helena and Liu, Feifei and Pemberton, Nils and Petersen, Jens and Rodrigo Blomqvist, Sandra and Smith, Reed W. and Svensson, Tor and Terstiege, Ina and Tyrchan, Christian and Yang, Wenzhen and Zhao, Shuchun and Öster, Linda (2017) Design and synthesis of soluble and cell-permeable PI3Kδ inhibitors for long-acting inhaled administration. Journal of Medicinal Chemistry . ISSN 0022-2623

Plieva, F. M. and Kochetkov, K. A. and Singh, Ishwar and Parmar, V. S. and Belokon', Y. N. and Lozinsky, V. I. (2000) Immobilization of hog pancreas lipase in macroporous poly(vinyl alcohol)-cryogel carrier for the biocatalysis in water-poor media. Biotechnology Letters, 22 (7). pp. 551-554. ISSN 0141-5492

Prosser, D. and Allman, M. and Grassby, Paul (1998) Oral transmucosal fentanyl. Anaesthesia, 53 (10). p. 1030. ISSN 0003-2409

Raj, Hanumantharao G. and Singh, Ishwar and Kohli, Ekta and Kumari, Ranju and Gupta, Garima and Tyagi, Yogesh K. and Kumar, Ajit and Prasad, Ashok K. and Kaushik, Narendra K. and Olsen, Carl E. and Watterson, Arthur C. and Parmar, Virinder S. (2003) Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 10: Identification of inhibitors for the liver microsomal acetoxycoumarin: protein transacetylase. Bioorganic and Medicinal Chemistry , 11 (6). pp. 1015-1019. ISSN 0968-0896

Rose, Peter and Faulkner, Kathy and Williamson, Gary and Mithen, Gary (2000) 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis, 21 (11). pp. 1983-1988. ISSN 0143-3334

Rose, Peter and Whiteman, Matt and Moore, Philip K. and Yi, Zhun Zhu (2005) Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Natural Product Reports, 22 (3). pp. 351-368. ISSN 0265-0568

Rosin, Claudia and Bates, Timothy E. and Skaper, Stephen D. (2004) Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of Neurochemistry, 90 (5). pp. 1173-1185. ISSN 0022-3042

Rosin, Claudia and Colombo, Sergio and Calver, Andrew A. and Bates, Timothy E. and Skaper, Stephen D. (2005) Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation. Glia, 52 (4). pp. 336-343. ISSN 0894-1491

Ryan-Kewley, Angela E. and Williams, David A. and Hepburn, Neill and Dixon, Ronald A. (2017) Non-antibiotic isotretinoin treatment differentially controls Propionibacterium acnes on skin of acne patients. Frontiers in Microbiology, 8 . ISSN 1664-302X

Schon, F. and Hart, P. E. and Hodgson, T. L. and Pambakian, A. L. M. and Ruprah, M. and Williamson, E.M. and Kennard, C. (1999) Suppression of pendular nystagmus by smoking cannabis in a patient with multiple sclerosis. Neurology, 53 (9). pp. 2209-2210. ISSN 0028-3878

Seaton, Colin C. and Blagden, Nicholas and Munshi, Tasnim and Scowen, Ian J. (2013) Creation of ternary multicomponent crystals by exploitation of charge-transfer interactions. Chemistry - A European Journal, 19 (32). pp. 10663-10671. ISSN 0947-6539

Selway, J. and Rigatti, R. and Storey, N. and Lu, J. and Willars, G. B. and Herbert, T. P. (2012) Evidence that Ca 2+ within the microdomain of the l-type voltage gated Ca 2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1. PLoS ONE, 7 (3). 0033004. ISSN 1932-6203

Shubber, Saif and Vllasaliu, Driton and Rauch, Cyril and Jordan, Faron and Illum, Lisbeth and Stolnik, Snjezana (2015) Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures. Pharmaceutical Research, 32 (2). pp. 516-527. ISSN 0724-8741

Singh, I. and Beuck, C. and Bhattacharya, A. and Hecker, W. and Parmar, V. S. and Weinhold, E. and Seitz, O. (2004) Abasic site stabilization by aromatic DNA base surrogates: High-affinity binding to a baseflipping DNA-methyltransferase. Pure and Applied Chemistry , 76 (7-8). pp. 1563-1570. ISSN 0033-4545

Singh, Ishwar and Freeman, Colin and Heaney, Frances (2011) Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase. European Journal of Organic Chemistry (33). pp. 6739-6746. ISSN 1434-193X

Singh, Ishwar and Freeman, Colin and Madder, Annemieke and Vyle, Joseph S. and Heaney, Frances (2012) Fast RNA conjugations on solid phase by strain-promoted cycloadditions. Organic and Biomolecular Chemistry, 10 (33). pp. 6633-6639. ISSN 1477-0520

Singh, Ishwar and Heaney, Frances (2010) Metal free, "click and click-click'' conjugation of ribonucleosides and 2'-OMe oligoribonucleotides on the solid phase. Organic and Biomolecular Chemistry, 8 (2). pp. 451-456. ISSN 1477-0520

Singh, Ishwar and Heaney, Frances (2011) Solid phase strain promoted "click'' modification of DNA via [3+2]-nitrile oxide-cyclooctyne cycloadditions. Chemical Communications, 47 (9). pp. 2706-2708. ISSN 1359-7345

Singh, Ishwar and Hecker, Walburga and Prasad, Ashok K. and Parmara, Virinder S. and Seitz, Oliver (2002) Local disruption of DNA-base stacking by bulky base surrogates. Chemical Communications (5). pp. 500-501. ISSN 1359-7345

Singh, Ishwar and Kohli, E. and Raj, H. G. and Gyanda, K. and Jain, S. K. and Tyagi, Y. K. and Gupta, G. and Kumari, R. and Kumar, A. and Pal, G. and Prasad, A. K. and Rastogi, R. C. and Olsen, C. E. and Jain, S. C. and Parmar, V. S. (2002) Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 9: comparison of acetoxy 4-methylcoumarins and other polyphenolic acetates reveal the specificity to acetoxy drug: protein transacetylase for pyran carbonyl group in proximity to the oxygen heteroatom. Bioorganic and Medicinal Chemistry, 10 (12). pp. 4103-4111. ISSN 0968-0896

Singh, Ishwar and Prasad, Ashok K. and Sharma, Ajendra K. and Saxena, Rajendra K. and Olsen, Carl E. and Cholli, Ashok L. and Samuelson, Lynne A. and Kumar, Jayant and Watterson, Arthur C. and Parmar, Virinder S. (2003) Synthetic and novel biocatalytic resolution studies on (+/-)-5/6/7-acetoxy-4-aryl-3,4-dihydrocoumarins. Bioorganic and Medicinal Chemistry, 11 (4). pp. 529-538. ISSN 0968-0896

Singh, Ishwar and Seitz, Oliver (2006) Diastereoselective synthesis of beta-aryl-C-nucleosides from 1,2-anhydrosugars. Organic Letters, 8 (19). pp. 4319-4322. ISSN 1523-7060

Singh, Ishwar and Vyle, Joseph S. and Heaney, Frances (2009) Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation. Chemical Communications, 45 (22). pp. 3276-3278. ISSN 1359-7345

Singh, Ishwar and Wendeln, Christian and Clark, Alasdair W. and Cooper, Jonathan M. and Ravoo, Bart Jan and Burley, Glenn A. (2013) Sequence-selective detection of double-stranded DNA sequences using pyrrole-imidazole polyamide microarrays. Journal of the American Chemical Society , 135 (9). pp. 3449-3457. ISSN 0002-7863

Singh, Ishwar and Zarafshani, Zoya and Heaney, Frances and Lutz, Jean-Francois (2011) Orthogonal modification of polymer chain-ends via sequential nitrile oxide-alkyne and azide-alkyne Huisgen cycloadditions. Polymer Chemistry, 2 (2). pp. 372-375. ISSN 1759-9954

Singh, Ishwar and Zarafshani, Zoya and Lutz, Jean-Francois and Heaney, Frances (2009) Metal-Free "Click'' chemistry: efficient polymer modification via 1,3-dipolar cycloaddition of nitrile oxides and alkynes. Macromolecules, 42 (15). pp. 5411-5413. ISSN 0024-9297

Soon, C. F. and Omar, W. I. W. and Berends, R. F. and Nayan, N. and Basri, H. and Tee, K. S. and Youseffi, M. and Blagden, Nicholas and Denyer, M. C. T. (2014) Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals. Micron, 56 . pp. 73-79. ISSN 0968-4328

Soon, Chin Phong and Khaghani, Seyed Ali and Youseffi, Mansour and Nayan, Nafarizal and Saim, Hashim and Britland, Stephen and Blagden, Nicholas and Denyer, Morgan Clive Thomas (2013) Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids and Surfaces B: Biointerfaces, 110 . pp. 156-162. ISSN 0927-7765

Subramanian, S. and Khan, I. and Korale, O. and Alhnan, M. A. and Ahmed, W. and Najlah, M. and Taylor, K. M. G. and Elhissi, A. (2016) A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies. International Journal of Pharmaceutics, 502 (1-2). pp. 18-27. ISSN 0378-5173

Telford, Richard and Seaton, Colin C. and Clout, Alexander and Buanz, Asma and Gaisford, Simon and Williams, Gareth R. and Prior, Timothy J. and Okoye, Chidera H. and Munshi, Tasnim and Scowen, Ian J. (2016) Stabilisation of metastable polymorphs: the case of paracetamol form III. Chem. Commun., 52 (81). pp. 12028-12031. ISSN 1359-7345

Vllasaliu, Driton and Alexander, Cameron and Garnett, Martin and Eaton , Mike and Stolnik, Snow (2012) Fc-mediated transport of nanoparticles across airway epithelial cell layers. Journal of Controlled Release, 158 (3). pp. 479-486. ISSN 0168-3659

Vllasaliu, Driton and Casettari, Luca and Bonacucina, Giulia and Cespi, Marco and Filippo Palmieri, Giovanni and Illum, Lisbeth (2013) Folic acid conjugated chitosan nanoparticles for tumor targeting of therapeutic and imaging agents. Pharmaceutical Nanotechnology, 1 (3). pp. 184-203. ISSN 2211-7385

Vllasaliu, Driton and Casettari, Luca and Fowler, Robyn and Exposito-Harris, Ruth and Garnett, Martin and Illum, Lisbeth and Stolnik, Snow (2012) Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study. International Journal of Pharmaceutics, 430 (1-2). pp. 151-160. ISSN 0378-5173

Vllasaliu, Driton and Exposito-Harris, Ruth and Heras, Angeles and Casettari, Luca and Garnett, Martin and Illum, Lisbeth and Stolnik, Snow (2010) Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution. International Journal of Pharmaceutics, 400 (1-2). pp. 183-193. ISSN 0378-5173

Vllasaliu, Driton and Falcone, Franco H. and Stolnik, Snjezana and Garnett, Martin (2014) Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules. Experimental Cell Research, 323 (1). pp. 218-231. ISSN 0014-4827

Vllasaliu, Driton and Fowler, Robyn and Garnett, Martin and Eaton , Mike and Stolnik, Snow (2011) Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochemical and Biophysical Research Communications, 415 (4). pp. 579-585. ISSN 0006-291X

Vllasaliu, Driton and Fowler, Robyn and Stolnik, Snjezana (2014) PEGylated nanomedicines: recent progress and remaining concerns. Expert Opinion on Drug Delivery, 11 (1). pp. 139-154. ISSN 1742-5247

Vllasaliu, Driton and Shubber, Saif and Fowler, Robyn and Garnett, Martin and Alexander, Cameron and Stolnik, Snow (2013) Epithelial toxicity of alkylglycoside surfactants. Journal of Pharmaceutical Sciences, 102 (1). pp. 114-125. ISSN 0975-1459

Vllasaliu, Driton and Shubber, Saif and Garnett, Martin and Alexander, Cameron and Eaton, Mike and Stolnik, Snow (2012) Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules. Biochemical and Biophysical Research Communications, 418 (1). pp. 128-133. ISSN 0006-291X

Wendeln, Christian and Singh, Ishwar and Rinnen, Stefan and Schulz, Christian and Arlinghaus, Heinrich F. and Burley, Glenn A. and Ravoo, Bart Jan (2012) Orthogonal, metal-free surface modification by strain-promoted azide-alkyne and nitrile oxide-alkene/alkyne cycloadditions. Chemical Science, 3 (8). pp. 2479-2484. ISSN 2041-6520

Williams, David R. and Chanos, P. (2012) Application of anti-listerial bacteriocins: monitoring enterocin expression by multiplex relative reverse transcription-PCR. Biochemical Society Transactions, 40 (6). pp. 1544-1548. ISSN 0300-5127

van Ravenzwaay, B. and Hardwick, T. D. and Needham, D. and Pethen, S. and Lappin, G. J. (2003) Comparative metabolism of 2,4-dichlorophenoxyacetic acid (2,4-D) in rat and dog. Xenobiotica: the fate of foreign compounds in biological systems, 33 (8). pp. 805-21. ISSN 0049-8254

Book Section

Lappin, Graham (2011) Microdosing: pharmacokinetic and metabolism data early in the drug development process. In: Pharmacokinetics in drug development: advanves and applications. Pharmacokinetics in Drug Development (3). Springer, New York. ISBN 9781441979377

Lappin, Graham (2010) Pharmacokinetics II: 14C-labelled microdosing in assessing drug pharmacokinetics at phase-0. In: Clinical Pharmacology, Current Topics and Case Studies. Springer, pp. 155-165. ISBN 9783709101438

Lappin, Graham and Tampion, J. and Stride, J. (1989) The biotransformation of monoterpenoids by tissue plant culture. In: Secondary metabolism in plant cell cultures. Cambridge University Press. ISBN UNSPECIFIED

Conference or Workshop contribution

Asghar, Zahid and Coupland, Carol and Siriwardena, Niro (2014) Influenza vaccination and risk of stroke: self-controlled case-series study. In: 42nd North American Primary Care Research Group (NAPCRG) Annual Meeting, 21-25 November 2014, New York.

Laparidou, Despina and Panayiotidis, Tony and Rodgers, Sarah and Avery, Tony and Wiseman, Janice and Rye, Chris and Bowler, Susan and Waring, Justin and Armstrong, Sarah and Mehta, Raj and Salema, Ndeshi and Bell, Brian and Ashcroft, Darren and Elliott, Rachel and Sheikh, Aziz and Chuter, Antony and Swanwick, Glen and Boyd, Matthew and Khunti, Kamlesh and Siriwardena, Niro (2017) Improving prescribing safety in general practices in the East Midlands through the Scaling Up PINCER intervention. In: Trent Regional SAPC Spring Meeting 2017, 21 March 2017, Lincoln.

Soon, C. F. and Youseffi, M. and Blagden, N. and Lobo, S. B. and Javid, F. A. and Denyer, M. C. T. (2009) Interactions of cells with elastic cholesteryl liquid crystals. In: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.


Bird, Joanna (2015) Neurotensin: a candidate for peptide-guided drug delivery. MRes thesis, University of Lincoln.

Cole, Hannah (2016) Chitosan-mediated vaccine delivery through the intestinal epithelium. Masters thesis, University of Lincoln.

Iyer, Abhishek (2016) DNA recognition and antimicrobial compounds: exploring the versatility of peptides. PhD thesis, University of Lincoln.

Osei-Baidoo, Jeremiah S. (2015) The effect of quinine products on tamoxifen resistant breast cancer cells. Masters thesis, University of Lincoln.

This list was generated on Wed Oct 18 00:38:32 2017 BST.