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4 methyl dextro glucuronic acid Age standardized incidence rate Air Pollutants Amines Amino acid substitutions Amino acids Animal cell culture Animal feeds Animals Antioxidants Antiviral Antiviral agents Aromatase Inhibitors Avena sativa BCMO1 protein, human Bacillus subtilis Bacteroides Bacteroides thetaiotaomicron Binding Sites Biofuels Botulinum Breast Neoplasms CD31 antigen CD45 antigen CD68 antigen CTLA 4 gene Calorimetry Cancer epidemiology Cancer immunotherapy Carbohydrate Metabolism Carbohydrates Carboxylesterase Cardiotonic Agents Carrier Proteins Catalytic properties Cell Adhesion Cell Line Cell Wall Cell signalling Cellular processes Clostridium thermocellum Cognitive assessment Combinatorial libraries Comprehension Corpus uteri cancer Crystallography, X-Ray Cysteine Cytotoxicity DNA Primers Diebetes Disability Elevated temperatures Embryonic stem cell markers Embryonic stem cells (ESCs) Endo-1,4-beta Xylanases Enzyme Inhibitors Enzymes Epidermal Cyst Eukaryotic Cells FOXP3 gene Flow interactions Fructans Fungal Proteins Galectin 3 Glycoside Hydrolases HSP27 Heat-Shock Proteins Histiocytoma, Benign Fibrous Human islets Human umbilical cord blood (HUCB) Humans Hydrogen Bonding Hydrogen sulfide Hydrogen sulphide Hydrogen-Ion Concentration Hydrolysis Hydrophobic and Hydrophilic Interactions Hydrophobic interactions Hydrophobicity Hyperthermostability Hyperthermostable Hypoxia Hypoxic stress Immunohistochemistry Immunotherapy Industrial applications Industrial uses Inflammation Mediators Insulin Intersexuality Intramolecular interactions Ischemia Kinetics Lectins Ligands Lipopolysaccharides Macrophages Malondialdehyde Melting point Melting temperatures Mesenchymal stem cells (MSCs) Messenger Mice Models, Chemical Models, Molecular Molecular Structure Molecular bases Morpholines Mutation Mutations Myocardial ischemia Myocardium NF-kappa B Neocallimastix Neocallimastix patriciarum Neoplasms, Multiple Primary Neuro2A Neuroblastoma New tools Oligosaccharides Open Reading Frames Organic acids, Ambient temperatures Organothiophosphorus Compounds Oxidation-Reduction Paediatric neuropsychology Paper pulps Parental experiences Penicillium Plant Proteins Polymorphism, Single Nucleotide Polysaccharides Primary structures Protein Binding Protein Conformation Protein Folding Protein Structure, Secondary Protein Structure, Tertiary, Bacillus subtilis Protein evolutions Protein structures RNA RNA interference Rats Rattus Recombinant Proteins SNARE Satisfaction Saudi Cancer Registry Sexual citizenship Single mutants Skin Diseases Skin Neoplasms Sprague-Dawley Structural bases Structure-Activity Relationship Substrate Specificity Substrate Specificity, Clostridium thermocellum Sulfides, Murinae Surface loops Syntaxin Target proteins Terminal regions Th1 cell Th17 cell Th2 cell Thermodynamics Transfection reagents Transgender Triticum Triticum aestivum Trypanosoma brucei Tuberculosis Tumor Markers, Biological Uronic Acids, Bacteria (microorganisms) Watercress X ray crystallography, Actinomycetales X-Ray Diffraction, Eukaryota Xylanase Xylanases, Protein folding, phenylalanine Young Adult acetic acid acetic acid derivative activating transcription factor 2 acute heart infarction allele amino acid substitution amino terminal sequence animal experiment animal model antioxidant antioxidant activity aromatase inhibitor, aged article asparagine aspartame bacterial cell wall bacterium adherence beta carotene beta carotene 15,15' monooxygenase beta sheet beta-Carotene 15,15'-Monooxygenase binding affinity binding site biocatalyst breast cancer breast tumor cancer adjuvant therapy cancer diagnosis cancer patient cancer survival capecitabine carbohydrate carbohydrate analysis carbohydrate binding module carbohydrate binding protein carbohydrate derivative carbohydrate esterase 3 carbohydrate metabolism carboxy terminal sequence carcinoma in situ case report catalase catalysis cell culture cell structure cell wall cellular immunity cellulase cellulosome chemical analysis chemistry codon colorectal cancer common acute lymphoblastic leukemia antigen concentration (parameters) concentration response controlled study crystal structure cyclophosphamide cystathionine gamma lyase cysteine derivative cytochrome c cytokeratin AE1 cytokeratin AE3 cytokine production cytology cytotoxic T lymphocyte antigen 4 desmin differential diagnosis disease association docetaxel dose response doxorubicin drug efficacy drug resistance drug response drug stability drug structure drug synthesis drug use dysplasia electron microscopy endo 1,4 beta xylanase enzyme activity enzyme binding enzyme conformation enzyme gh11 enzyme specificity enzyme structure enzyme substrate enzyme synthesis enzymology epithelial membrane antigen esterase eukaryote exolevanase female ferulic acid ferulic acid 1,5 arabinofuranose alpha1,3 xylotriose fibroxanthoma follow up forehead fructan fructose oligosaccharide fructosidase furan galacturonic acid gamma interferon gene gene expression gene frequency gene identification gene library gene silencing genetic code genetic polymorphism genetic variability genetics glioma glucosaminidase glucuronic acid glutathione glutathione peroxidase glycine granulocyte gyy 4137 heart muscle cell heart muscle ischemia heart protection heart ventricle heat shock protein 27 helper cell heterozygote histidine histology histopathology human human cell human experiment human tissue hydrogen bond hydrogen sulfide hydrolase hydrolysis hydrophobicity immune dysregulation immunofluorescence test immunoglobulin enhancer binding protein in vitro study inflammation innate immunity interleukin 10 interleukin 17 interleukin 1beta interleukin 2 interleukin 4 interleukin 5 interleukin 6 inulin keratinization keratosis kinetics levan levo arabinofuranose ligand binding lipid peroxidation lipopolysaccharide lipoprotein low drug dose macrophage major clinical study male malonaldehyde mammography mastectomy melan A messenger RNA metabolism, Alleles methodology microscopy middle aged mitochondrial protein mitochondrion mitochondrion swelling mitosis molecular cloning molecular evolution monoclonal antibody HMB 45 monocyte morpholine derivative multiple cycle treatment mutant natural science nitric oxide nonhuman nucleotide sequence open reading frame outcome assessment oxidation reduction reaction oxidative stress oxidizing agent oxidoreductase oxygen pathology peripheral blood mononuclear cell phenotype phylogeny plant cell polymerase chain reaction polysaccharide polysaccharide, article postmenopause prescription primer DNA, amino acid sequence priority journal priority journal, Activating Transcription Factor 2 priority journal, Apoenzymes proline propargylglycine prostaglandin E2 protein S 100 protein carbohydrate interaction protein degradation protein determination protein domain protein engineering protein evxyn11 protein evxyn11 ts protein expression protein folding protein function protein function, Harness protein structure protein transport protein xip 1 protozoal protein rat recombinant protein, adult regulatory T lymphocyte retinol palmitate reverse transcription polymerase chain reaction review, Aged s allylcysteine s propargylcysteine s propylcysteine screening sebaceous cyst serine single nucleotide polymorphism site directed mutagenesis skin nodule skin tumor smooth muscle actin, aged sodium hydrogen sulfide squamous epithelium, Aged, 80 and over stoichiometry, Bacillus subtilis sulfide superoxide dismutase suppressor cell survival rate thermodynamics, Animalia, Codon thermostability thermostability, Bacterial Proteins thiol oxidase threonine transcription factor FOXP3 treatment outcome triacylglycerol tricyclic antidepressant agent, article tumor necrosis factor alpha tumor necrosis factor alpha, advanced cancer ultrastructure unclassified drug unclassified drug, antiinflammatory activity unclassified drug, article uronic acid, article vegetable protein vitamin metabolism vitamin supplementation xylan endo 1,3 beta xylosidase xylan endo 1,3 beta xylosidase, article xylan, alpha helix zyz 802
Number of items at this level: 565.

4 methyl dextro glucuronic acid

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Age standardized incidence rate

Alghamdi, Ibrahim G. and Hussain, Issam I. and Alghamdi, Mohamed S. and El-Sheemy, Mohamed A. (2013) The incidence rate of corpus uteri cancer among females in Saudi Arabia: an observational descriptive epidemiological analysis of data from Saudi Cancer Registry 2001-2008. International Journal of Women's Health, 6 (1). pp. 141-147. ISSN 1179-1411

Air Pollutants

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Amines

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Amino acid substitutions

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Amino acids

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Animal cell culture

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Animal feeds

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Animals

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Antioxidants

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Antiviral

Biswas, Subhajit and Field, Hugh (2007) Isolation and characterization of an helicase-primase inhibitor (HPI)-resistant HSV-1 mutant in tissue culture and a mouse-skin model. Antiviral Research, 74 (3). A34-A34. ISSN 0166-3542

Antiviral agents

Biswas, S. and Sukla, S. and Goldner, T. and Field, H. and Kropeit, D. and Paulsen, D. and Welbers, A. and Ruebsamen-Schaeff, H. and Zimmermann, H. and Birkmann, A. (2014) Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model. Antimicrobial Agents and Chemotherapy, 58 (7). pp. 3843-3852. ISSN 0066-4804

Aromatase Inhibitors

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

Avena sativa

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

BCMO1 protein, human

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Bacillus subtilis

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Bacteroides

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Bacteroides thetaiotaomicron

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Binding Sites

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Biofuels

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Botulinum

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

Breast Neoplasms

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

CD31 antigen

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

CD45 antigen

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

CD68 antigen

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

CTLA 4 gene

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Calorimetry

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Cancer epidemiology

Alghamdi, Ibrahim G. and Hussain, Issam I. and Alghamdi, Mohamed S. and El-Sheemy, Mohamed A. (2013) The incidence rate of corpus uteri cancer among females in Saudi Arabia: an observational descriptive epidemiological analysis of data from Saudi Cancer Registry 2001-2008. International Journal of Women's Health, 6 (1). pp. 141-147. ISSN 1179-1411

Cancer immunotherapy

Aloysius, Mark M. and Mc Kechnie, Alastair J. and Robins, Richard A. and Verma, Chandan and Eremin, Jennifer M. and Farzaneh, Farzin and Habib, Nagy A and Bhalla, Joti and Hardwick, Nicola R. and Satthaporn, Sukchai and Sreenivasan, Thiagarajan and El-Sheemy, Mohammed and Eremin, Oleg (2009) Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs. Journal of Translational Medicine, 7 (1). p. 18. ISSN 1479-5876

Satthaporn, Sukchai and Aloysius, Mark M. and Robins, Richard A. and Verma, Chandan and Chuthapisith, Suebwong and Mckechnie, Alasdair J. and El-Sheemy, Mohamad and Vassanasiri, Wichai and Valerio, David and Clark, David and Jibril, Jibril A. and Eremin, Oleg (2008) Ex vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha. BMC Immunology, 9 (1). p. 32. ISSN 1471-2172

Carbohydrate Metabolism

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Carbohydrates

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Carboxylesterase

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cardiotonic Agents

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Carrier Proteins

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Catalytic properties

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Cell Adhesion

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Cell Line

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Cell Wall

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Cell signalling

Li, Ling and Rose, Peter and Moore, Philip K. (2011) Hydrogen sulfide and cell signaling. Annual Review of Pharmacology and Toxicology, 51 (1). pp. 169-187. ISSN 0362-1642

Cellular processes

Pfister, S. and Ahrabi, S. and Zalmas, L.-P. and Sarkar, S. and Aymard, F. and Bachrati, C. and Helleday, T. and Legube, G. and LaThangue, N. and Porter, A. and Humphrey, T. C. (2014) SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability. Cell Reports, 7 (6). pp. 2006-2018. ISSN 2211-1247

Clostridium thermocellum

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cognitive assessment

Stark, Daniel and Thomas, Sophie and Dawson, Dave and Talbot, Emily and Bennett, Emily and Starza-Smith, Arleta (2014) Paediatric neuropsychological assessment: an analysis of parents' perspectives. Social Care and Neurodisability, 5 (1). pp. 41-50. ISSN 2042-0919

Combinatorial libraries

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Comprehension

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Corpus uteri cancer

Alghamdi, Ibrahim G. and Hussain, Issam I. and Alghamdi, Mohamed S. and El-Sheemy, Mohamed A. (2013) The incidence rate of corpus uteri cancer among females in Saudi Arabia: an observational descriptive epidemiological analysis of data from Saudi Cancer Registry 2001-2008. International Journal of Women's Health, 6 (1). pp. 141-147. ISSN 1179-1411

Crystallography, X-Ray

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Cysteine

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Cytotoxicity

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

DNA Primers

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Diebetes

Hodgkin, M. N. and Hills, C. E. and Squires, P. E. (2008) The calcium-sensing receptor and insulin secretion: a role outside systemic control 15 years on. Journal of Endocrinology, 199 (1). pp. 1-4. ISSN 0022-0795

Disability

Davy, Zowie (2010) The disabling affects of a sexed system: an exploration of intersexuality, transgender and sexual citizenship. In: Sex & disability: politics, identity, access. Disability Press, Leeds, pp. 179-195. ISBN 0954902661

Elevated temperatures

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Embryonic stem cell markers

Hussain, Issam and Magd, Salah A. and Eremin, Oleg and El-Sheemy, Mohamed (2013) Evaluation of human umbilical cord blood as a source of embryonic stem cells. European Scientific Journal, 9 (24). ISSN 1857-7881

Embryonic stem cells (ESCs)

Hussain, Issam and Magd, Salah A. and Eremin, Oleg and El-Sheemy, Mohamed (2013) Evaluation of human umbilical cord blood as a source of embryonic stem cells. European Scientific Journal, 9 (24). ISSN 1857-7881

Endo-1,4-beta Xylanases

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Enzyme Inhibitors

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Enzymes

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Rose, Peter and Faulkner, Kathy and Williamson, Gary and Mithen, Gary (2000) 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis, 21 (11). pp. 1983-1988. ISSN 0143-3334

Epidermal Cyst

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Eukaryotic Cells

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

FOXP3 gene

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Flow interactions

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Fructans

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Fungal Proteins

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Galectin 3

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Glycoside Hydrolases

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

HSP27 Heat-Shock Proteins

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Histiocytoma, Benign Fibrous

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Human islets

Hodgkin, M. N. and Hills, C. E. and Squires, P. E. (2008) The calcium-sensing receptor and insulin secretion: a role outside systemic control 15 years on. Journal of Endocrinology, 199 (1). pp. 1-4. ISSN 0022-0795

Human umbilical cord blood (HUCB)

Hussain, Issam and Magd, Salah A. and Eremin, Oleg and El-Sheemy, Mohamed (2013) Evaluation of human umbilical cord blood as a source of embryonic stem cells. European Scientific Journal, 9 (24). ISSN 1857-7881

Humans

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Hydrogen Bonding

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Hydrogen sulfide

Li, Ling and Rose, Peter and Moore, Philip K. (2011) Hydrogen sulfide and cell signaling. Annual Review of Pharmacology and Toxicology, 51 (1). pp. 169-187. ISSN 0362-1642

Liu, XinHua and Pan, LiLong and Zhuo, Yang and Gong, QiHai and Rose, Peter and Zhu, YiZhun (2010) Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress. Biological and Pharmaceutical Bulletin, 33 (9). pp. 1550-1554. ISSN 0918-6158

Hydrogen sulphide

Li, Ling and Rose, Peter and Moore, Philip K. (2011) Hydrogen sulfide and cell signaling. Annual Review of Pharmacology and Toxicology, 51 (1). pp. 169-187. ISSN 0362-1642

Hydrogen-Ion Concentration

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Hydrolysis

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Hydrophobic and Hydrophilic Interactions

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Hydrophobic interactions

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Hydrophobicity

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Hyperthermostability

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Hyperthermostable

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Hypoxia

Wang, Qian and Liu, Hong-Rui and Mu, Qing and Rose, Peter and Zhu, Yi Zhun (2009) S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway. Journal of Cardiovascular Pharmacology, 54 (2). pp. 139-146. ISSN 0160-2446

Hypoxic stress

Liu, XinHua and Pan, LiLong and Zhuo, Yang and Gong, QiHai and Rose, Peter and Zhu, YiZhun (2010) Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress. Biological and Pharmaceutical Bulletin, 33 (9). pp. 1550-1554. ISSN 0918-6158

Immunohistochemistry

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Immunotherapy

Aloysius, Mark M. and Mc Kechnie, Alastair J. and Robins, Richard A. and Verma, Chandan and Eremin, Jennifer M. and Farzaneh, Farzin and Habib, Nagy A and Bhalla, Joti and Hardwick, Nicola R. and Satthaporn, Sukchai and Sreenivasan, Thiagarajan and El-Sheemy, Mohammed and Eremin, Oleg (2009) Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs. Journal of Translational Medicine, 7 (1). p. 18. ISSN 1479-5876

Industrial applications

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Industrial uses

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Inflammation Mediators

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Insulin

Hodgkin, M. N. and Hills, C. E. and Squires, P. E. (2008) The calcium-sensing receptor and insulin secretion: a role outside systemic control 15 years on. Journal of Endocrinology, 199 (1). pp. 1-4. ISSN 0022-0795

Intersexuality

Davy, Zowie (2010) The disabling affects of a sexed system: an exploration of intersexuality, transgender and sexual citizenship. In: Sex & disability: politics, identity, access. Disability Press, Leeds, pp. 179-195. ISBN 0954902661

Intramolecular interactions

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Ischemia

Wang, Qian and Liu, Hong-Rui and Mu, Qing and Rose, Peter and Zhu, Yi Zhun (2009) S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway. Journal of Cardiovascular Pharmacology, 54 (2). pp. 139-146. ISSN 0160-2446

Kinetics

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Lectins

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Ligands

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Lipopolysaccharides

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Macrophages

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Malondialdehyde

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Melting point

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Melting temperatures

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Mesenchymal stem cells (MSCs)

Hussain, Issam and Magd, Salah A. and Eremin, Oleg and El-Sheemy, Mohamed (2013) Evaluation of human umbilical cord blood as a source of embryonic stem cells. European Scientific Journal, 9 (24). ISSN 1857-7881

Messenger

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Mice

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Models, Chemical

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Models, Molecular

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Molecular Structure

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Molecular bases

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Morpholines

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Mutation

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Ormiston, Mark L. and Southgate, Laura and Treacy, Carmen and Pepke-Zaba, Joanna and Trembath, Richard C. and Machado, Rajiv D. and Morrell, Nicholas W. (2013) Assessment of a pulmonary origin for blood outgrowth endothelial cells by examination of identical twins harboring a BMPR2 mutation. American Journal of Respiratory and Critical Care Medicine, 188 (2). pp. 258-260. ISSN 1073-449X

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Mutations

Biswas, Subhajit and Sukla, Soumi and Field, Hugh J. (2009) Drug resistance mutations in HSV-1 UL5 selected using a helicase–primase inhibitor: frequency and effects on virus growth and pathogenicity. Antiviral Research, 82 (2). A68-A69. ISSN 0166-3542

Myocardial ischemia

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Myocardium

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

NF-kappa B

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Neocallimastix

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Neocallimastix patriciarum

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Neoplasms, Multiple Primary

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Neuro2A

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

Neuroblastoma

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

New tools

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Oligosaccharides

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Open Reading Frames

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Organic acids, Ambient temperatures

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Organothiophosphorus Compounds

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Oxidation-Reduction

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Paediatric neuropsychology

Stark, Daniel and Thomas, Sophie and Dawson, Dave and Talbot, Emily and Bennett, Emily and Starza-Smith, Arleta (2014) Paediatric neuropsychological assessment: an analysis of parents' perspectives. Social Care and Neurodisability, 5 (1). pp. 41-50. ISSN 2042-0919

Paper pulps

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Parental experiences

Stark, Daniel and Thomas, Sophie and Dawson, Dave and Talbot, Emily and Bennett, Emily and Starza-Smith, Arleta (2014) Paediatric neuropsychological assessment: an analysis of parents' perspectives. Social Care and Neurodisability, 5 (1). pp. 41-50. ISSN 2042-0919

Penicillium

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Plant Proteins

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Polymorphism, Single Nucleotide

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Polysaccharides

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Primary structures

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Protein Binding

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Protein Conformation

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Protein Folding

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Protein Structure, Secondary

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Protein Structure, Tertiary, Bacillus subtilis

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Protein evolutions

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Protein structures

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

RNA

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

RNA interference

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Rats

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Rattus

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Recombinant Proteins

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

SNARE

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

Satisfaction

Stark, Daniel and Thomas, Sophie and Dawson, Dave and Talbot, Emily and Bennett, Emily and Starza-Smith, Arleta (2014) Paediatric neuropsychological assessment: an analysis of parents' perspectives. Social Care and Neurodisability, 5 (1). pp. 41-50. ISSN 2042-0919

Saudi Cancer Registry

Alghamdi, Ibrahim G. and Hussain, Issam I. and Alghamdi, Mohamed S. and El-Sheemy, Mohamed A. (2013) The incidence rate of corpus uteri cancer among females in Saudi Arabia: an observational descriptive epidemiological analysis of data from Saudi Cancer Registry 2001-2008. International Journal of Women's Health, 6 (1). pp. 141-147. ISSN 1179-1411

Sexual citizenship

Davy, Zowie (2010) The disabling affects of a sexed system: an exploration of intersexuality, transgender and sexual citizenship. In: Sex & disability: politics, identity, access. Disability Press, Leeds, pp. 179-195. ISBN 0954902661

Single mutants

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Skin Diseases

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Skin Neoplasms

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Sprague-Dawley

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Structural bases

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Structure-Activity Relationship

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Substrate Specificity

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Substrate Specificity, Clostridium thermocellum

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Sulfides, Murinae

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

Surface loops

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Syntaxin

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

Target proteins

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Terminal regions

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Th1 cell

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Th17 cell

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Th2 cell

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Thermodynamics

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Transfection reagents

Arsenault, Jason and Cuijpers, Sabine A. G. and Ferrari, Enrico and Niranjan, Dhevahi and Rust, Aleksander and Leese, Charlotte and O'Brien, John A. and Binz, Thomas and Davletov, Bazbek (2014) Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells. Journal of Neurochemistry, 129 (5). pp. 781-791. ISSN 0022-3042

Transgender

Davy, Zowie (2010) The disabling affects of a sexed system: an exploration of intersexuality, transgender and sexual citizenship. In: Sex & disability: politics, identity, access. Disability Press, Leeds, pp. 179-195. ISBN 0954902661

Triticum

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Triticum aestivum

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Trypanosoma brucei

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Tuberculosis

Gernaey, A. M. and Minnikin, D. E. and Copley, M. S. and Dixon, R. A. and Middleton, J. C. and Roberts, C. A. (2001) Mycolic acids and ancient {DNA} confirm an osteological diagnosis of tuberculosis. Tuberculosis , 81 (4). 259 - 265. ISSN 1472-9792

Tumor Markers, Biological

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Uronic Acids, Bacteria (microorganisms)

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Watercress

Rose, Peter and Faulkner, Kathy and Williamson, Gary and Mithen, Gary (2000) 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis, 21 (11). pp. 1983-1988. ISSN 0143-3334

X ray crystallography, Actinomycetales

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

X-Ray Diffraction, Eukaryota

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Xylanase

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Xylanases, Protein folding, phenylalanine

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Young Adult

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

acetic acid

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

acetic acid derivative

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

activating transcription factor 2

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

acute heart infarction

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

allele

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

amino acid substitution

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

amino terminal sequence

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

animal experiment

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

animal model

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

antioxidant

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

antioxidant activity

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

aromatase inhibitor, aged

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

article

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

asparagine

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

aspartame

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

bacterial cell wall

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

bacterium adherence

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

beta carotene

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

beta carotene 15,15' monooxygenase

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

beta sheet

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

beta-Carotene 15,15'-Monooxygenase

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

binding affinity

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

binding site

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

biocatalyst

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

breast cancer

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

breast tumor

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

cancer adjuvant therapy

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

cancer diagnosis

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

cancer patient

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

cancer survival

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

capecitabine

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

carbohydrate

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

carbohydrate analysis

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

carbohydrate binding module

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

carbohydrate binding protein

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

carbohydrate derivative

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

carbohydrate esterase 3

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

carbohydrate metabolism

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

carboxy terminal sequence

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

carcinoma in situ

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

case report

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

catalase

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

catalysis

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

cell culture

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

cell structure

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

cell wall

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

cellular immunity

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

cellulase

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

cellulosome

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

chemical analysis

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

chemistry

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

codon

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

colorectal cancer

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

common acute lymphoblastic leukemia antigen

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

concentration (parameters)

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

concentration response

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

controlled study

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

crystal structure

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

cyclophosphamide

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

cystathionine gamma lyase

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

cysteine derivative

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

cytochrome c

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

cytokeratin AE1

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

cytokeratin AE3

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

cytokine production

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

cytology

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

cytotoxic T lymphocyte antigen 4

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

desmin

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

differential diagnosis

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

disease association

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

docetaxel

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

dose response

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

doxorubicin

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

drug efficacy

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

drug resistance

Biswas, Subhajit and Sukla, Soumi and Field, Hugh J. (2009) Drug resistance mutations in HSV-1 UL5 selected using a helicase–primase inhibitor: frequency and effects on virus growth and pathogenicity. Antiviral Research, 82 (2). A68-A69. ISSN 0166-3542

drug response

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

drug stability

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

drug structure

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

drug synthesis

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

drug use

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

dysplasia

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

electron microscopy

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

endo 1,4 beta xylanase

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

enzyme activity

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

enzyme binding

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

enzyme conformation

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

enzyme gh11

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

enzyme specificity

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

enzyme structure

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

enzyme substrate

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

enzyme synthesis

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

enzymology

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

epithelial membrane antigen

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

esterase

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

eukaryote

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

exolevanase

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

female

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

ferulic acid

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

ferulic acid 1,5 arabinofuranose alpha1,3 xylotriose

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

fibroxanthoma

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

follow up

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

forehead

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

fructan

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

fructose oligosaccharide

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

fructosidase

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

furan

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

galacturonic acid

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

gamma interferon

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

gene

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

gene expression

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

gene frequency

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

gene identification

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

gene library

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

gene silencing

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

genetic code

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

genetic polymorphism

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

genetic variability

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

genetics

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

glioma

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

glucosaminidase

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

glucuronic acid

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

glutathione

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

glutathione peroxidase

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

glycine

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

granulocyte

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

gyy 4137

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

heart muscle cell

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

heart muscle ischemia

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

heart protection

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

heart ventricle

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

heat shock protein 27

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

helper cell

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

heterozygote

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

histidine

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

histology

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

histopathology

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

human

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

human cell

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

human experiment

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

human tissue

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

hydrogen bond

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

hydrogen sulfide

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

hydrolase

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

hydrolysis

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

hydrophobicity

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

immune dysregulation

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

immunofluorescence test

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

immunoglobulin enhancer binding protein

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

in vitro study

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

inflammation

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

innate immunity

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

interleukin 10

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

interleukin 17

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

interleukin 1beta

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

interleukin 2

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

interleukin 4

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

interleukin 5

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

interleukin 6

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

inulin

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

keratinization

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

keratosis

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

kinetics

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

levan

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

levo arabinofuranose

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

ligand binding

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

lipid peroxidation

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

lipopolysaccharide

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

lipoprotein

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

low drug dose

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

macrophage

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

major clinical study

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

male

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

malonaldehyde

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

mammography

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

mastectomy

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

melan A

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

messenger RNA

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

metabolism, Alleles

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

methodology

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

microscopy

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

middle aged

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

mitochondrial protein

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

mitochondrion

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

mitochondrion swelling

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

mitosis

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

molecular cloning

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

molecular evolution

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

monoclonal antibody HMB 45

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

monocyte

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

morpholine derivative

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

multiple cycle treatment

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

mutant

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

natural science

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

nitric oxide

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

nonhuman

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

nucleotide sequence

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

open reading frame

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

outcome assessment

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

oxidation reduction reaction

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

oxidative stress

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

oxidizing agent

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

oxidoreductase

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

oxygen

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

pathology

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

peripheral blood mononuclear cell

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

phenotype

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

phylogeny

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

plant cell

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

polymerase chain reaction

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

polysaccharide

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

polysaccharide, article

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

postmenopause

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

prescription

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

primer DNA, amino acid sequence

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

priority journal

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

priority journal, Activating Transcription Factor 2

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

priority journal, Apoenzymes

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

proline

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

propargylglycine

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

prostaglandin E2

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

protein S 100

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

protein carbohydrate interaction

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

protein degradation

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

protein determination

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

protein domain

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

protein engineering

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

protein evxyn11

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

protein evxyn11 ts

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

protein expression

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

protein folding

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

protein function

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

protein function, Harness

Montanier, Cedric and Money, Victoria A. and Pires, Virginia M. R. and Flint, James E. and Pinheiro, Benedita A. and Goyal, Arun and Prates, Jose A. M. and Izumi, Atsushi and Stalbrand, Henrik and Morland, Carl and Cartmell, Alan and Kolenova, Katarina and Topakas, Evangelos and Dodson, Eleanor J. and Bolam, David N. and Davies, Gideon J. and Fontes, Carlos M. G. A. and Gilbert, Harry J. (2009) The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. PLoS Biology, 7 (3). e1000071. ISSN 1544-9173

protein structure

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

protein transport

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

protein xip 1

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

protozoal protein

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

rat

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

recombinant protein, adult

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

regulatory T lymphocyte

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

retinol palmitate

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

reverse transcription polymerase chain reaction

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

review, Aged

Samphao, S. and Eremin, J. M. and El-Sheemy, M. and Eremin, O. (2009) Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. Surgeon, 7 (1). pp. 42-55. ISSN 1479-666x

s allylcysteine

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

s propargylcysteine

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

s propylcysteine

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

screening

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

sebaceous cyst

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

serine

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

single nucleotide polymorphism

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

site directed mutagenesis

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

skin nodule

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

skin tumor

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

smooth muscle actin, aged

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

sodium hydrogen sulfide

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

squamous epithelium, Aged, 80 and over

Arsenovic, N. and Senyszyn, Steph and Naik, V. and Reed, M. and Moreira, R. (2009) Trichilemmal cyst with carcinoma in situ within an atypical fibroxanthoma. American Journal of Dermatopathology, 31 (6). pp. 587-590. ISSN 0193-1091

stoichiometry, Bacillus subtilis

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

sulfide

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

superoxide dismutase

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

suppressor cell

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

survival rate

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

thermodynamics, Animalia, Codon

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

thermostability

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

thermostability, Bacterial Proteins

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

thiol oxidase

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

threonine

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

transcription factor FOXP3

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

treatment outcome

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

triacylglycerol

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

tricyclic antidepressant agent, article

Walker, A. J. and Grainge, M and Bates, T. E. and Card, T. R. (2012) Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis. Cancer Causes and Control, 23 (12). pp. 1959-1964. ISSN 0957-5243

tumor necrosis factor alpha

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

tumor necrosis factor alpha, advanced cancer

Verma, C. and Eremin, J. M. and Robins, A. and Bennett, A. J. and Cowley, G. P. and El-Sheemy, M. A. and Jibril, J. A. and Eremin, O. (2013) Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC. Journal of Translational Medicine, 11 (1). p. 16. ISSN 1479-5876

ultrastructure

Basu, Somsuvro and Leonard, Joanne C. and Desai, Nishal and Mavridou, Despoina A. I. and Tang, Kong Ho and Goddard, Alan D. and Ginger, Michael L. and Lukes, Julius and Allen, James W. A. (2013) Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists. Eukaryotic Cell, 12 (2). pp. 343-355. ISSN 1535-9778

unclassified drug

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

unclassified drug, antiinflammatory activity

Whiteman, M. and Li, L. and Rose, P. and Tan, C.-H. and Parkinson, D. B. and Moore, P. K. (2010) The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants and Redox Signaling, 12 (10). pp. 1147-1154. ISSN 1523-0864

unclassified drug, article

Cuskin, Fiona and Flint, James E. and Gloster, Tracey M. and Morland, Carl and Basle, Arnaud and Henrissat, Bernard and Coutinho, Pedro M. and Strazzulli, Andrea and Solovyova, Alexandra S. and Davies, Gideon J. and Gilbert, Harry J. (2012) How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences, 109 (51). pp. 20889-20894. ISSN 0027-8424

uronic acid, article

Montanier, Cedric and Van Bueren, Alicia Lammerts and Dumon, Claire and Flint, James E. and Correia, Marcia A. and Prates, Jose A. and Firbank, Susan J. and Lewis, Richard J. and Grondin, Gilles G. and Ghinet, Mariana G. and Gloster, Tracey M. and Herve, Cecile and Knox, J. Paul and Talbot, Brian G. and Turkenburg, Johan P. and Kerovuo, Janne and Brzezinski, Ryszard and Fontes, Carlos M. G. A. and Davies, Gideon J. and Boraston, Alisdair B. and Gilbert, Harry J. (2009) Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences, 106 (9). pp. 3065-3070. ISSN 0027-8424

vegetable protein

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

vitamin metabolism

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

vitamin supplementation

Leung, W. C. and Hessel, S. and Meplan, C. and Flint, J. and Oberhauser, V. and Tourniaire, F. and Hesketh, J. E. and Von Lintig, J. and Lietz, G. (2009) Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB Journal, 23 (4). pp. 1041-1053. ISSN 0892-6638

xylan endo 1,3 beta xylosidase

Dumon, Claire and Varvak, Alexander and Wall, Mark A. and Flint, James E. and Lewis, Richard J. and Lakey, Jeremy H. and Morland, Carl and Luginbuhl, Peter and Healey, Shaun and Todaro, Thomas and DeSantis, Grace and Sun, May and Parra-Gessert, Lilian and Tan, Xuqiu and Weiner, David P. and Gilbert, Harry J. (2008) Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure. The Journal of biological chemistry, 283 (33). pp. 22557-22564. ISSN 0021-9258

xylan endo 1,3 beta xylosidase, article

Vardakou, Maria and Dumon, Claire and Murray, James W. and Christakopoulos, Paul and Weiner, David P. and Juge, Nathalie and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases. Journal of Molecular Biology, 375 (5). pp. 1293-1305. ISSN 0022-2836

xylan, alpha helix

Correia, Marcia A. S. and Prates, Jose A. M. and Bras, Joana and Fontes, Carlos M. G. A. and Newman, Joseph A. and Lewis, Richard J. and Gilbert, Harry J. and Flint, James E. (2008) Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides Insights into the mechanism of substrate recognition. Journal of Molecular Biology, 379 (1). pp. 64-72. ISSN 0022-2836

zyz 802

Wang, Qian and Wang, Xian-Li and Liu, Hong-Rui and Rose, Peter and Zhu, Yi-Zhun (2010) Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H2S production. Antioxidants & Redox Signaling, 12 (10). pp. 1155-1165. ISSN 1523-0864

This list was generated on Thu Jul 31 11:30:11 2014 BST.