Article

Hamilton, A. and Mittal, S. and Barnardo, M. C .N. M. and Fuggle, S. V. and Friend, P. and Gough, S. C. L. and Simmonds, M. (2015) Genetic variation in Caveolin-1 correlates with long-term pancreas transplant outcome. American Journal of Transplantation . ISSN 1600-6143

Chand, S. and Chue, C. D. and Edwards, N. C. and Hodson, J. and Simmonds, M. J. and Hamilton, A. and Gough, S. C. L. and Harper, L. and Steeds, R. P. and Townend, J. N. and Ferro, C. J. and Borrows, R. (2015) Endothelial nitric oxide synthase single nucleotide polymorphism and left ventricular function in early chronic kidney disease. PLoS ONE, 10 (1). ISSN 1932-6203

Hamilton, A. and Newby, P. R. and Carr-Smith, J. D. and Disanto, G. and Allahabadia, A. and Armitage, M. and Brix, T. H. and Taylor, J.C. and Vaidya, B. and Wass, J. A. and Wiersinga, W. M. and Weetman, A. P. and Ramagopalan, S. V. and Franklyn, J. A. and Gough, S. C. L. and Simmonds, M. J. (2014) Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe. Journal of Clinical Endocrinology and Metabolism, 99 (8). ISSN 0021-972X

Medici, M. and Porcu, E. and Pistis, G. and Teumer, A. and Brown, S. J. and Jensen, R. A. and Rawal, R. and Roef, G. L. and Plantinga, T. S. and Vermeulen, S. H. and Lahti, J. and Simmonds, M. J. and Husemoen, L. N. N. and Freathy, R. M. and Shields, B. M. and Pietzner, D. and Nagy, R. and Broer, L. and Chaker, L. and Korevaar, T. I. M. and Plia, M. G. and Sala, C. and Volker, U. and Richards, J. B. and Sweep, F. C. and Gieger, C. and Corre, T. and Kajantie, E. and Thuesen, B. and Taes, Y. E. and Visser, W. E. and Hattersley, A. T. and Kratzsch, J. and Hamilton, A. and Li, W. and Homuth, G. and Lobina, M. and Mariotti, S. and Soranzo, N. and Cocca, M. and Nauck, M. and Spielhagen, C. and Ross, A. and Arnold, A. and van de Bunt, M. and Liyanarachchi, S. and Heier, M. and Grabe, H. J. and Masciullo, C. and Galesloot, T. E. and Lim, E. M. and Reischl, E. and Leedman, P. J. and Lai, S. and Delitala, A. and Bremner, A. P. and Philips, D. I. W. and Beilby, J. P. and Mulas, A. and Vocale, M. and Abecasis, G. and Forsen, T. and James, A. and Widen, E. and Hui, J. and Prokisch, H. and Rietzschel, E. E. and Palotie, A. and Feddema, P. and Fletcher, S. J. and Schramm, K. and Rotter, J. I. and Kluttig, A. and Radke, D. and Traglia, M. and Surdulescu, G. L. and He, H. and Franklyn, J. A. and Tiller, D. and Vaidya, B. and de Meyer, T. and Jørgensen, T. and Eriksson, J. G. and O’Leary, P. C. and Wichmann, E. and Hermus, A. R. and Psaty, B. M. and Ittermann, T. and Hofman, A. and Bosi, E. and Schlessinger, D. and Wallaschofski, H. and Pirastu, N. and Aulchenko, Y.S. and de la Chapelle, A. and Netea-Maier, R.T. and Gough, S.C.L. and Meyer zu Schwabedissen, H. and Frayling, T.M. and Kaufman, J.M. and Linneberg, A. and Raikkonen, K. and Smit, J.W.A. and Kiemeney, L.A. and Rivadeneira, F. and Uitterlinden, A.G. and Walsh, J.P. and Meisinger, C. and den Heijer, M. and Visser, T.J. and Spector, T.D. and Wilson, S.G. and Volzke, H. and Cappola, A. and Toniolo, D. and Sanna, S. and Naitza, S. and Peeters, R.P. (2014) Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genetics, 10 (2). ISSN 15537390

Simmonds, M. J. and Kavvoura, F. K. and Brand, O. J. and Newby, P. R. and Jackson, L. E. and Hargreaves, C. E. and Franklyn, J. A. and Gough, S. C. L. (2014) Skewed X chromosome inactivation and female preponderance in autoimmune thyroid disease: an association study and meta-analysis. Journal of Clinical Endocrinology and Metabolism, 99 (1). ISSN 0021-972X

Chand, S. and Holle, J. U. and Hilhorst, M. and Simmonds, M. J. and Smith, S. and Kamesh, L. and Hewins, P. and McKnight, A. J. and Maxwell, A. P. and Willem Cohen Tervaert, J. and Wieczorek, S. and Harper, L. and Borrows, R. (2013) Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis. PLoS ONE, 8 (7). ISSN 1932-6203

Hunt, K. A. and Mistry, V. and Bockett, N. A. and Ahmad, T. and Ban, M. and Barker, J. N. and Barrett, J. C. and Blackburn, H. and Brand, O. J. and Burren, O. and Capon, F. and Compston, A. and Gough, S. C. L. and Jostins, L. and Kong, Y. and Lee, J. C. and Lek, M. and MacArthur, D. G. and Mansfield, J. C. and Mathew, C. G. and Mein, C. A. and Mirza, M. and Nutland, S. and Onengut-Gumuscu, S. and Papouli, E. and Parkes, M. and Rich, S. S. and Sawcer, S. and Satsangi, J. and Simmonds, M. J. and Trembath, R. C. and Walker, N. M. and Wozniak, E. and Todd, J. A. and Simpson, M. A. and Plagnol, V. and van Heel, D. A. (2013) Negligible impact of rare autoimmune-locus coding-region variants on missing heritability. Nature, 498 (7453). pp. 232-235. ISSN 0028-0836

Simmonds, Matthew J. and Benavente, David and Brand, Oliver J. and Moore, Jason and Ball, Simon and Ferro, Charles J. and Briggs, David and Gough, Stephen C. L. and Borrows, Richard J. (2013) Skewing of female X-chromosome inactivation: an epigenetic risk factor for kidney transplantation outcome. Transplantation, 95 (5). e25-e28. ISSN 0041-1337

Cooper, J. D. and Simmonds, M. J. and Walker, N.M. and Burren, O. and Brand, O.J. and Guo, H. and Wallace, C. and Stevens, H. and Coleman, G and Franklyn, J.A. and Todd, J.A. and Gough, S.C.L. (2012) Seven newly identified loci for autoimmune thyroid disease. Human Molecular Genetics, 21 (23). pp. 5202-5208. ISSN 0964-6906

Moore, Jason and McKnight, Amy Jayne and Döhler, Bernd and Simmonds, Matthew J. and Courtney, Aisling E. and Brand, Oliver J. and Briggs, David and Ball, Simon and Cockwell, Paul and Patterson, Christopher C. and Maxwell, Alexander P. and Gough, Stephen C. L. and Opelz, Gerhard and Borrows, Richard (2012) Donor ABCB1 variant associates with increased risk for kidney allograft failure. Journal of the American Society of Nephrology, 23 (11). pp. 1891-1899. ISSN 1046-6673

Hunt, K. A. and Smyth, D. J. and Balschun, T. and Ban, M. and Mistry, V. and Ahmed, T. and Barrett, J. C. and Bhaw-Rosun, L. and Bockett, N. A. and Brand, O. J. and Brouwer, E. and Concannon, P. and Cooper, J. D. and Dias, K-R. M. and van Diemen, C. C. and Dubois, P.C. and Edkins, S. and Fölster-Holst, R. and Fransen, K. and Glass, D. N. and Heap, G. A. R. and Hofmann, S. and Huizinga, T. W. J. and Hunt, S. and Langford, C. and Lee, J. and Mansfield, J. and Giovanna Marrosu, M. and Mathew, C. G. and Mein, C.A. and Müller-Quernheim, J. and Nutland, S. and Onengut-Gumuscu, S. and Ouwehand, W. and Pearce, K. and Prescott, N. and Posthumus, M. D. and Potter, S. and Rosati, G. and Sambrook, J. and Satsangi, J. and Schreiber, S. and Shtir, C. and Simmonds, M. J. and Sudman, M. and Thompson, S. D. and Toes, R. and Trynka, G. and Vyse, T. J. and Walker, N. M. and Weidinger, S. and Zhernakova, A. and Zoledziewska, M. and Weersma, R.K. and Gough, S.C.L. and Sawcer, S. and Wijmenga, C. and Parkes, M. and Cucca, F. and Franke, A. and Deloukas, P. and Rich, S. S. and Todd, J. A. and van Heel, D. A. (2011) Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nature Genetics, 44 (1). pp. 3-5. ISSN 10614036

Plagnol, Vincent and Howson, Joanna M. M. and Smyth, Deborah J. and Walker, Neil and Hafler, Jason P. and Wallace, Chris and Stevens, Helen and Jackson, Laura and Simmonds, Matthew J. and T1D Genetics Consortium, - and Bingley, Polly J. and Gough, Stephen C. and Todd, John A. (2011) Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genetics, 7 (8). ISSN 1553-7390

Simmonds, Matthew J. and Brand, Oliver J. and Barrett, Jeffrey C. and Newby, Paul R. and Franklyn, Jayne A. and Gough, Stephen C. L. (2010) Association of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3. Clinical Endocrinology, 73 (5). pp. 654-660. ISSN 0300-0664

Newby, Paul R. and Pickles, Oliver J. and Mazumdar, Samaresh and Brand, Oliver J. and Carr-Smith, Jacqueline D. and Pearce, Simon H. S. and Franklyn, Jayne A. and Evans, David M. and Simmonds, Matthew J. and Gough, Stephen C. L. and Welcome Trust Case-Control Consortium (WTCCC), . (2010) Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study. European Journal of Human Genetics, 18 (9). pp. 1021-1026. ISSN 1018-4813

Buckham, T. A. and McKnight, A. J. and Benevente, D. and Courtney, A. E. and Patterson, C. C. and Simmonds, Matthew J. and Gough, S. C. L. and Middleton, D. and Borrows, R. and Maxwell, A. P. (2010) Evaluation of five interleukin genes for association with end-stage renal disease in white Europeans. American Journal of Nephrology, 32 (2). pp. 103-108. ISSN 0250-8095

Yesmin, K. and Hargreaves, C. and Newby, P. R. and Brand, O. J. and Heward, J. M. and Franklyn, J. A. and Gough, S. C. L. and Simmonds, M. J. (2010) Association of FcGRIIa with Graves' disease: a potential role for dysregulated autoantibody clearance in disease onset/progression. Clinical Endocrinology, 73 (1). pp. 119-125. ISSN 0300-0664

Moore, J. and McKnight, A.J. and Simmonds, M. J. and Courtney, A. E. and Hanvesakul, R. and Brand, O. J. and Briggs, D. and Ball, S. and Cockwell, P. and Patterson, C.C. and Maxwell, A. P. and Gough, S. C. L. and Borrows, R. (2010) Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure. JAMA - Journal of the American Medical Association, 303 (13). pp. 1282-1287. ISSN 0098-7484

Simmonds, Matthew J. and Yesmin, Kadja and Newby, Paul R. and Brand, Oliver J. and Franklyn, Jayne A. and Gough, Stephen C. L. (2010) Confirmation of association of chromosome 5q31-33 with United Kingdom caucasian Graves' disease. Thyroid, 20 (4). pp. 413-417. ISSN 1050-7256

Craddock, Nick and Hurles, Matthew E. and Cardin, Niall and Pearson, Richard D. and Plagnol, Vincent and Robson, Samuel and Vukcevic, Damjan and Barnes, Chris and Conrad, Donald F. and Giannoulatou, Eleni and Holmes, Chris and Marchini, Jonathan L. and Stirrups, Kathy and Tobin, Martin D. and Wain, Louise V. and Yau, Chris and Aerts, Jan and Ahmad, Tariq and Daniel Andrews, T. and Arbury, Hazel and Attwood, Anthony and Auton, Adam and Ball, Stephen G. and Balmforth, Anthony J. and Barrett, Jeffrey C. and Barroso, Inês and Barton, Anne and Bennett, Amanda J. and Bhaskar, Sanjeev and Blaszczyk, Katarzyna and Bowes, John and Brand, Oliver J. and Braund, Peter S. and Bredin, Francesca and Breen, Gerome and Brown, Morris J. and Bruce, Ian N. and Bull, Jaswinder and Burren, Oliver S. and Burton, John and Byrnes, Jake and Caesar, Sian and Clee, Chris M. and Coffey, Alison J. and Connell, John M. C. and Cooper, Jason D. and Dominiczak, Anna F. and Downes, Kate and Drummond, Hazel E. and Dudakia, Darshna and Dunham, Andrew and Ebbs, Bernadette and Eccles, Diana and Edkins, Sarah and Edwards, Cathryn and Elliot, Anna and Emery, Paul and Evans, David M. and Evans, Gareth and Eyre, Steve and Farmer, Anne and Nicol Ferrier, I. and Feuk, Lars and Fitzgerald, Tomas and Flynn, Edward and Forbes, Alistair and Forty, Liz and Franklyn, Jayne A. and Freathy, Rachel M. and Gibbs, Polly and Gilbert, Paul and Gokumen, Omer and Gordon-Smith, Katherine and Gray, Emma and Green, Elaine and Groves, Chris J. and Grozeva, Detelina and Gwilliam, Rhian and Hall, Anita and Hammond, Naomi and Hardy, Matt and Harrison, Pile and Hassanali, Neelam and Hebaishi, Husam and Hines, Sarah and Hinks, Anne and Hitman, Graham A and Hocking, Lynne and Howard, Eleanor and Howard, Philip and Howson, Joanna M. M. and Hughes, Debbie and Hunt, Sarah and Isaacs, John D. and Jain, Mahim and Jewell, Derek P. and Johnson, Toby and Jolley, Jennifer D. and Jones, Ian R. and Jones, Lisa A. and Kirov, George and Langford, Cordelia F. and Lango-Allen, Hana and Mark Lathrop, G. and Lee, James and Lee, Kate L. and Lees, Charlie and Lewis, Kevin and Lindgren, Cecilia M. and Maisuria-Armer, Meeta and Maller, Julian and Mansfield, John and Martin, Paul and Massey, Dunecan C. O. and McArdle, Wendy L. and McGuffin, Peter and McLay, Kirsten E. and Mentzer, Alex and Mimmack, Michael L. and Morgan, Ann E. and Morris, Andrew P. and Mowat, Craig and Myers, Simon and Newman, William and Nimmo, Elaine R. and O’Donovan, Michael C. and Onipinla, Abiodun and Onyiah, Ifejinelo and Ovington, Nigel R. and Owen, Michael J. and Palin, Kimmo and Parnell, Kirstie and Pernet, David and Perry, John R. B. and Phillips, Anne and Pinto, Dalila and Prescott, Natalie J. and Prokopenko, Inga and Quail, Michael A. and Rafelt, Suzanne and Rayner, Nigel W. and Redon, Richard and Reid, David M. and Renwick, Anthony and Ring, Susan M. and Robertson, Neil and Russell, Ellie and St Clair, David and Sambrook, Jennifer G. and Sanderson, Jeremy D. and Schuilenburg, Helen and Scott, Carol E. and Scott, Richard and Seal, Sheila and Shaw-Hawkins, Sue and Shields, Beverley M. and Simmonds, Matthew J. and Smyth, Debbie J. and Somaskantharajah, Elilan and Spanova, Katarina and Steer, Sophia and Stephens, Jonathan and Stevens, Helen E. and Stone, Millicent A. and Su, Zhan and Symmons, Deborah P. M. and Thompson, John R. and Thomson, Wendy and Travers, Mary E. and Turnbull, Clare and Valsesia, Armand and Walker, Mark and Walker, Neil M. and Wallace, Chris and Warren-Perry, Margaret and Watkins, Nicholas A. and Webster, John and Weedon, Michael N. and Wilson, Anthony G. and Woodburn, Matthew and Wordsworth, B. Paul and Young, Allan H. and Zeggini, Eleftheria and Carter, Nigel P. and Frayling, Timothy M. and Lee, Charles and McVean, Gil and Munroe, Patricia B. and Palotie, Aarno and Sawcer, Stephen J. and Scherer, Stephen W. and Strachan, David P. and Tyler-Smith, Chris and Brown, Matthew A. and Burton, Paul R. and Caulfield, Mark J. and Compston, Alastair and Farrall, Martin and Gough, Stephen C. L. and Hall, Alistair S. and Hattersley, Andrew T. and Hill, Adrian V. S. and Mathew, Christopher G. and Pembrey, Marcus and Satsangi, Jack and Stratton, Michael R. and Worthington, Jane and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P. and McCarthy, Mark I. and Ouwehand, Willem H. and Parkes, Miles and Rahman, Nazneen and Todd, John A. and Samani, Nilesh J. and Donnelly, Peter (2010) Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464 (7289). pp. 713-720. ISSN 0028-0836

Boelaert, Kristien and Newby, Paul R. and Simmonds, Matthew J. and Holder, Roger L. and Carr-Smith, Jacqueline D. and Heward, Joanne M. and Manji, Nilusha and Allahabadia, Amit and Armitage, Mary and Chatterjee, Krishna V. and Lazarus, John H. and Pearce, Simon H. and Vaidya, Bijay and Gough, Stephen C. and Franklyn, Jayne A. (2010) Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease. American Journal of Medicine, 123 (2). 183.e1-183.e9. ISSN 0002-9343

Wood, Alice M. and Needham, Michelle and Simmonds, Matthew J. and Newby, Paul R. and Gough, Stephen C. and Stockley, Robert A. (2009) Phenotypic differences in alpha 1 antitrypsin-deficient sibling pairs may relate to genetic variation. COPD: Journal of Chronic Obstructive Pulmonary Disease, 5 (6). pp. 353-359. ISSN 1541-2555

Brand, O. J. and Barrett, J. C. and Simmonds, M. J. and Newby, P. R. and McCabe, C. J. and Bruce, C. K. and Kysela, B. and Carr-Smith, J. D. and Brix, T. and Hunt, P. J. and Wiersinga, W. M. and Hegedus, L. and Connell, J. and Wass, J. A. H. and Franklyn, J. A. and Weetman, A. P. and Heward, J. M. and Gough, S. C. L. (2009) Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease. Human Molecular Genetics, 18 (9). pp. 1704-1713. ISSN 0964-6906

Hafler, J. P. and Maier, L. M. and Cooper, J. D. and Plagnol, V. and Hinks, A. and Simmonds, M. J. and Stevens, H. and Walker, N. and Healy, B. and Howson, J. M. M. and Maisuria, M. and Duley, S. and Coleman, G. and Gough, S. C. L. and Worthington, J. and Kuchroo, V. K. and Wicker, L. S. and Todd, J. A. and IMSGC, . (2009) CD226 Gly307Ser association with multiple autoimmune diseases. Genes and Immunity, 10 (1). pp. 5-10. ISSN 1466-4879

Wood, Alice M. and Simmonds, Matthew J. and Bayley, Darren L. and Newby, Paul R. and Gough, Stephen C. and Stockley, Robert A. (2008) The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency. Respiratory Research, 9 (52). ISSN 1465-9921

Zeitlin, A. A. and Heward, J. M. and Newby, P. R. and Carr-Smith, J. D. and Franklyn, J. A. and Gough, S. C. L. and Simmonds, M. J. (2008) Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease. Genes and Immunity, 9 (4). pp. 358-363. ISSN 1466-4879

Nejentsev, Sergey and Howson, Joanna M. M. and Walker, Neil M. and Szeszko, Jeffrey and Field, Sarah F. and Stevens, Helen E. and Reynolds, Pamela and Hardy, Matthew and King, Erna and Masters, Jennifer and Hulme, John and Maier, Lisa M. and Smyth, Deborah and Bailey, Rebecca and Cooper, Jason D. and Ribas, Gloria and Campbell, R. Duncan and Clayton, David G. and Todd, John A. and Burton, Paul R. and Clayton, David G. and Cardon, Lon R. and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P. and McCarthy, Mark I. and Ouwehand, Willem H. and Samani, Nilesh J. and Todd, John A. and Donnelly, Peter and Barrett, Jeffrey C. and Burton, Paul R. and Davison, Dan and Donnelly, Peter and Easton, Doug and Evans, David and Leung, Hin-Tak and Marchini, Jonathan L. and Morris, Andrew P. and Spencer, Chris C. 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Burton, Paul R and Clayton, David G and Cardon, Lon R and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P and McCarthy, Mark I and Ouwehand, Willem H and Samani, Nilesh J and Todd, John A and Donnelly (Chair), Peter and Barrett, Jeffrey C and Burton, Paul R and Davison, Dan and Donnelly, Peter and Easton, Doug and Evans, David M and Leung, Hin-Tak and Marchini, Jonathan L and Morris, Andrew P and Spencer, Chris CA and Tobin, Martin D and Cardon, Lon R and Clayton, David G and Attwood, Antony P and Boorman, James P and Cant, Barbara and Everson, Ursula and Hussey, Judith M and Jolley, Jennifer D and Knight, Alexandra S and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Prowse, Christopher V and Stevens, Helen E and Taylor, Niall C and Walters, Graham R and Walker, Neil M and Watkins, Nicholas A and Winzer, Thilo and Todd, John A and Ouwehand, Willem H and Jones, Richard W and McArdle, Wendy L and Ring, Susan M and Strachan, David P and Pembrey, Marcus and Breen, Gerome and Clair, David St and Caesar, Sian and Gordon-Smith, Katharine and Jones, Lisa and Fraser, Christine and Green, Elaine K and Grozeva, Detelina and Hamshere, Marian L and Holmans, Peter A and Jones, Ian R and Kirov, George and Moskivina, Valentina and Nikolov, Ivan and O'Donovan, Michael C and Owen, Michael J and Craddock, Nick and Collier, David A and Elkin, Amanda and Farmer, Anne and Williamson, Richard and McGuffin, Peter and Young, Allan H and Ferrier, I Nicol and Ball, Stephen G and Balmforth, Anthony J and Barrett, Jennifer H and Bishop, Timothy D and Iles, Mark M and Maqbool, Azhar and Yuldasheva, Nadira and Hall, Alistair S and Braund, Peter S and Burton, Paul R and Dixon, Richard J and Mangino, Massimo and Stevens, Suzanne and Tobin, Martin D and Thompson, John R and Samani, Nilesh J and Bredin, Francesca and Tremelling, Mark and Parkes, Miles and Drummond, Hazel and Lees, Charles W and Nimmo, Elaine R and Satsangi, Jack and Fisher, Sheila A and Forbes, Alastair and Lewis, Cathryn M and Onnie, Clive M and Prescott, Natalie J and Sanderson, Jeremy and Matthew, Christopher G and Barbour, Jamie and Mohiuddin, M Khalid and Todhunter, Catherine E and Mansfield, John C and Ahmad, Tariq and Cummings, Fraser R and Jewell, Derek P and Webster, John and Brown, Morris J and Clayton, David G and Lathrop, Mark G and Connell, John and Dominiczak, Anna and Samani, Nilesh J and Marcano, Carolina A Braga and Burke, Beverley and Dobson, Richard and Gungadoo, Johannie and Lee, Kate L and Munroe, Patricia B and Newhouse, Stephen J and Onipinla, Abiodun and Wallace, Chris and Xue, Mingzhan and Caulfield, Mark and Farrall, Martin and Barton, Anne and Bruce, Ian N and Donovan, Hannah and Eyre, Steve and Gilbert, Paul D and Hilder, Samantha L and Hinks, Anne M and John, Sally L and Potter, Catherine and Silman, Alan J and Symmons, Deborah PM and Thomson, Wendy and Worthington, Jane and Clayton, David G and Dunger, David B and Nutland, Sarah and Stevens, Helen E and Walker, Neil M and Widmer, Barry and Todd, John A and Frayling, Timothy M and Freathy, Rachel M and Lango, Hana and Perry, John R B and Shields, Beverley M and Weedon, Michael N and Hattersley, Andrew T and Hitman, Graham A and Walker, Mark and Elliott, Kate S and Groves, Christopher J and Lindgren, Cecilia M and Rayner, Nigel W and Timpson, Nicolas J and Zeggini, Eleftheria and McCarthy, Mark I and Newport, Melanie and Sirugo, Giorgio and Lyons, Emily and Vannberg, Fredrik and Hill, Adrian V S and Bradbury, Linda A and Farrar, Claire and Pointon, Jennifer J and Wordsworth, Paul and Brown, Matthew A and Franklyn, Jayne A and Heward, Joanne M and Simmonds, Matthew J and Gough, Stephen CL and Seal, Sheila and Stratton, Michael R and Rahman, Nazneen and Ban, Maria and Goris, An and Sawcer, Stephen J and Compston, Alastair and Conway, David and Jallow, Muminatou and Newport, Melanie and Sirugo, Giorgio and Rockett, Kirk A and Kwiatkowski, Dominic P and Bumpstead, Suzannah J and Chaney, Amy and Downes, Kate and Ghori, Mohammed JR and Gwilliam, Rhian and Hunt, Sarah E and Inouye, Michael and Keniry, Andrew and King, Emma and McGinnis, Ralph and Potter, Simon and Ravindrarajah, Rathi and Whittaker, Pamela and Widden, Claire and Withers, David and Deloukas, Panos and Leung, Hin-Tak and Nutland, Sarah and Stevens, Helen E and Walker, Neil M and Todd, John A and Easton, Doug and Clayton, David G and Burton, Paul R and Tobin, Martin D and Barrett, Jeffrey C and Evans, David M and Morris, Andrew P and Cardon, Lon R and Cardin, Niall J and Davison, Dan and Ferreira, Teresa and Pereira-Gale, Joanne and Hallgrimsdóttir, Ingeleif B and Howie, Bryan N and Marchini, Jonathan L and Spencer, Chris CA and Su, Zhan and Teo, Yik Ying and Vukcevic, Damjan and Donnelly, Peter and Bentley, David and Brown, Matthew A and Cardon, Lon R and Caulfield, Mark and Clayton, David G and Compston, Alastair and Craddock, Nick and Deloukas, Panos and Donnelly, Peter and Farrall, Martin and Gough, Stephen CL and Hall, Alistair S and Hattersley, Andrew T and Hill, Adrian V S and Kwiatkowski, Dominic P and Matthew, Christopher G and McCarthy, Mark I and Ouwehand, Willem H and Parkes, Miles and Pembrey, Marcus and Rahman, Nazneen and Samani, Nilesh J and Stratton, Michael R and Todd, John A and Worthington, Jane and Mitchell, Sarah L and Newby, Paul R and Brand, Oliver J and Carr-Smith, Jackie and Pearce, Simon H S and Gough, Stephen C L and McGinnis, R and Keniry, A and Deloukas, P and Reveille, John D and Zhou, Xiaodong and Bradbury, Linda A and Sims, Anne-Marie and Dowling, Alison and Taylor, Jacqueline and Doan, Tracy and Cardon, Lon R and Davis, John C and Pointon, Jennifer J and Savage, Laurie and Ward, Michael M and Learch, Thomas L and Weisman, Michael H and Wordsworth, Paul and Brown, Matthew A (2007) Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics, 39 (11). pp. 1329-1337. ISSN 1061-4036

Syed, A. A. and Simmonds, M. J. and Brand, O. J. and Franklyn, J. A. and Gough, S. C. L. and Heward, J. M. (2007) Preliminary evidence for interaction of PTPN12 polymorphism with TSHR genotype and association with Graves' ophthalmopathy. Clinical Endocrinology, 67 (5). pp. 663-667. ISSN 0300-0664

Simmonds, M. J. and Howson, J. M. M. and Heward, J. M. and Carr-Smith, J. and Franklyn, J. A. and Todd, J. A. and Gough, S. C. L. (2007) A novel and major association of HLA-C in Graves' disease that eclipses the classical HLA-DRB1 effect. Human Molecular Genetics, 16 (18). pp. 2149-2153. ISSN 0964-6906

Todd, J. A. and Walker, N. M. and Cooper, J. D. and Smyth, D. J. and Downes, K. and Plagnol, V. and Bailey, R. and Nejentsev, S. and Field, S. F. and Payne, F. and Lowe, C. E. and Szeszko, J. S. and Hafler, J. P. and Zeitels, L. and Yang, J. H. M. and Vella, A. and Nutland, S. and Stevens, H. E. and Schuilenburg, H. and Coleman, G. and Maisuria, M. and Meadows, W. and Smink, L. J. and Healy, B. and Burren, O. S. and Lam, A. A. C. and Ovington, N. R. and Allen, J. and Adlem, E. and Leung, H-T. and Wallace, C. and Howson, J. M. M. and Guja, C. and Ionescu-Tırgoviste, C. and Genetics of T1D in Finland, . and Simmonds, M. J. and Heward, J. M. and Gough, S. C. L. and WTCCC, . and Dunger, D. B. and Wicker, L. S. and Clayton, D. G. (2007) Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nature Genetics, 39 (7). pp. 857-864. ISSN 1061-4036

Newby, P. R. and Roberts-Davies, E. L. and Brand, O. J. and Heward, J. M. and Franklyn, J. A. and Gough, S. C. L. and Simmonds, M. J. (2007) Tag SNP screening of the PDCD1 gene for association with Graves' disease. Clinical Endocrinology, 67 (1). pp. 125-128. ISSN 0300-0664

Burton, Paul R. and Clayton, David G. and Cardon, Lon R. and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P. and McCarthy, Mark I. and Ouwehand, Willem H. and Samani, Nilesh J. and Todd, John A. and Donnelly, Peter and Barrett, Jeffrey C. and Burton, Paul R. and Davison, Dan and Donnelly, Peter and Easton, Doug and Evans, David and Leung, Hin-Tak and Marchini, Jonathan L. and Morris, Andrew P. and Spencer, Chris C. A. and Tobin, Martin D. and Cardon, Lon R. and Clayton, David G. and Attwood, Antony P. and Boorman, James P. and Cant, Barbara and Everson, Ursula and Hussey, Judith M. and Jolley, Jennifer D. and Knight, Alexandra S. and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Prowse, Christopher V. and Stevens, Helen E. and Taylor, Niall C. and Walters, Graham R. and Walker, Neil M. and Watkins, Nicholas A. and Winzer, Thilo and Todd, John A. and Ouwehand, Willem H. and Jones, Richard W. and McArdle, Wendy L. and Ring, Susan M. and Strachan, David P. and Pembrey, Marcus and Breen, Gerome and St Clair, David and Caesar, Sian and Gordon-Smith, Katherine and Jones, Lisa and Fraser, Christine and Green, Elaine K. and Grozeva, Detelina and Hamshere, Marian L. and Holmans, Peter A. and Jones, Ian R. and Kirov, George and Moskvina, Valentina and Nikolov, Ivan and O'Donovan, Michael C. and Owen, Michael J. and Craddock, Nick and Collier, David A. and Elkin, Amanda and Farmer, Anne and Williamson, Richard and McGuffin, Peter and Young, Allan H. and Ferrier, I. Nicol and Ball, Stephen G. and Balmforth, Anthony J. and Barrett, Jennifer H. and Bishop, D. Timothy and Iles, Mark M. and Maqbool, Azhar and Yuldasheva, Nadira and Hall, Alistair S. and Braund, Peter S. and Burton, Paul R. and Dixon, Richard J. and Mangino, Massimo and Stevens, Suzanne and Tobin, Martin D. and Thompson, John R. and Samani, Nilesh J. and Bredin, Francesca and Tremelling, Mark and Parkes, Miles and Drummond, Hazel and Lees, Charles W. and Nimmo, Elaine R. and Satsangi, Jack and Fisher, Sheila A. and Forbes, Alastair and Lewis, Cathryn M. and Onnie, Clive M. and Prescott, Natalie J. and Sanderson, Jeremy and Mathew, Christopher G. and Barbour, Jamie and Mohiuddin, M. Khalid and Todhunter, Catherine E. and Mansfield, John C. and Ahmad, Tariq and Cummings, Fraser R. and Jewell, Derek P. and Webster, John and Brown, Morris J. and Clayton, David G. and Lathrop, G. Mark and Connell, John and Dominiczak, Anna and Samani, Nilesh J. and Marcano, Carolina A. Braga and Burke, Beverley and Dobson, Richard and Gungadoo, Johannie and Lee, Kate L. and Munroe, Patricia B. and Newhouse, Stephen J. and Onipinla, Abiodun and Wallace, Chris and Xue, Mingzhan and Caulfield, Mark and Farrall, Martin and Barton, Anne and and Genomics (BRAGGS), The Biologics in RA Genetics and Bruce, Ian N. and Donovan, Hannah and Eyre, Steve and Gilbert, Paul D. and Hider, Samantha L. and Hinks, Anne M. and John, Sally L. and Potter, Catherine and Silman, Alan J. and Symmons, Deborah P. M. and Thomson, Wendy and Worthington, Jane and Clayton, David G. and Dunger, David B. and Nutland, Sarah and Stevens, Helen E. and Walker, Neil M. and Widmer, Barry and Todd, John A. and Frayling, Timothy M. and Freathy, Rachel M. and Lango, Hana and Perry, John R. B. and Shields, Beverley M. and Weedon, Michael N. and Hattersley, Andrew T. and Hitman, Graham A. and Walker, Mark and Elliott, Kate S. and Groves, Christopher J. and Lindgren, Cecilia M. and Rayner, Nigel W. and Timpson, Nicholas J. and Zeggini, Eleftheria and McCarthy, Mark I. and Newport, Melanie and Sirugo, Giorgio and Lyons, Emily and Vannberg, Fredrik and Hill, Adrian V. S. and Bradbury, Linda A. and Farrar, Claire and Pointon, Jennifer J. and Wordsworth, Paul and Brown, Matthew A. and Franklyn, Jayne A. and Heward, Joanne M. and Simmonds, Matthew J. and Gough, Stephen C. L. and Seal, Sheila and Susceptibility Collaboration (UK), Breast Cancer and Stratton, Michael R. and Rahman, Nazneen and Ban, Maria and Goris, An and Sawcer, Stephen J. and Compston, Alastair and Conway, David and Jallow, Muminatou and Newport, Melanie and Sirugo, Giorgio and Rockett, Kirk A. and Kwiatkowski, Dominic P. and Bumpstead, Suzannah J. and Chaney, Amy and Downes, Kate and Ghori, Mohammed J. R. and Gwilliam, Rhian and Hunt, Sarah E. and Inouye, Michael and Keniry, Andrew and King, Emma and McGinnis, Ralph and Potter, Simon and Ravindrarajah, Rathi and Whittaker, Pamela and Widden, Claire and Withers, David and Deloukas, Panos and Leung, Hin-Tak and Nutland, Sarah and Stevens, Helen E. and Walker, Neil M. and Todd, John A. and Easton, Doug and Clayton, David G. and Burton, Paul R. and Tobin, Martin D. and Barrett, Jeffrey C. and Evans, David and Morris, Andrew P. and Cardon, Lon R. and Cardin, Niall J. and Davison, Dan and Ferreira, Teresa and Pereira-Gale, Joanne and Hallgrimsdóttir, Ingileif B. and Howie, Bryan N. and Marchini, Jonathan L. and Spencer, Chris C. A. and Su, Zhan and Teo, Yik Ying and Vukcevic, Damjan and Donnelly, Peter and Bentley, David and Brown, Matthew A. and Cardon, Lon R. and Caulfield, Mark and Clayton, David G. and Compston, Alistair and Craddock, Nick and Deloukas, Panos and Donnelly, Peter and Farrall, Martin and Gough, Stephen C. L. and Hall, Alistair S. and Hattersley, Andrew T. and Hill, Adrian V. S. and Kwiatkowski, Dominic P. and Mathew, Christopher G. and McCarthy, Mark I. and Ouwehand, Willem H. and Parkes, Miles and Pembrey, Marcus and Rahman, Nazneen and Samani, Nilesh J. and Stratton, Michael R. and Todd, John A. and Worthington, Jane (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447 (7145). pp. 661-678. ISSN 0028-0836

Simmonds, M. J. and Heward, J. M. and Barrett, J. C. and Franklyn, J. A. and Gough, S. C. L. (2006) Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74. Clinical Endocrinology, 65 (4). pp. 429-432. ISSN 0300-0664

Zeitlin, A. A. and Heward, J. M. and Brand, O. J. and Newby, P. R. and Franklyn, J. A. and Gough, S. C. L. and Simmonds, M. J. (2006) Use of Tag single nucleotide polymorphisms (SNPs) to screen PTPN21: no association with Graves' disease. Clinical Endocrinology, 65 (3). pp. 380-384. ISSN 0300-0664

Simmonds, Matthew J. and Heward, J. M. and Carr-Smith, J. and Foxall, H. and Franklyn, J. A. and Gough, S. C. L. (2006) Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease. Journal of Clinical Endocrinology and Metabolism, 91 (3). pp. 1056-1061. ISSN 0021-972X

Simmonds, M. J. and Heward, J. M. and Franklyn, J. A. and Gough, S. C. L. (2005) IL-13 and chromosome 5q31-q33: problems of identifying association within regions of linkage to Graves' disease. Clinical Endocrinology, 63 (6). pp. 695-697. ISSN 0300-0664

Simmonds, M. J. and Heward, J. M. and Franklyn, J. A. and Gough, S. C. L. (2005) The CD40 Kozak SNP: a new susceptibility loci for Graves' disease? Clinical Endocrinology, 63 (2). pp. 232-233. ISSN 0300 0664

Simmonds, Matthew J. and Howson, Joanna M. M. and Heward, Joanne M. and Cordell, Heather J. and Foxall, Helen and Carr-Smith, Jackie and Gibson, Sarah M. and Walker, Neil and Tomer, Yaron and Franklyn, Jayne A. and Todd, John A. and Gough, Stephen C. L. (2005) Regression mapping of association between the human leukocyte antigen region and Graves' disease. American Journal of Human Genetics, 76 (1). pp. 157-163. ISSN 0002-9297

Heward, J. M. and Simmonds, M. J. and Carr-Smith, J. and Foxall, H. and Franklyn, J. A. and Gough, S. C. L. (2004) A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians. Clinical Endocrinology, 61 (2). pp. 269-272. ISSN 0300-0664

Simmonds, M. J. and Heward, J.M. and Howson, J.M.M. and Foxall, H. and Nithiyananthan, R. and Franklyn, J.A. and Gough, S.C.L. (2004) A systematic approach to the assesment of known TNF-alpha polymorphisms in Graves' disease. Genes and Immunity, 5 (4). pp. 267-273. ISSN 1466-4879

Simmonds, Matthew J. and Heward, Joanne M. and Kelly, M. Ann and Allahabadia, Amit and Foxall, Helen and Gordon, Caroline and Franklyn, Jayne A. and Gough, Stephen C. L. (2002) A nonsense mutation in exon 2 of the DNase I gene is not present in UK subjects with systemic lupus erythematosus and Graves' disease: Comment on the article by Rood et al. Arthritis and Rheumatism, 46 (11). pp. 3109-3110. ISSN 0004-3591

Review

Duff, Claire E. and Simmonds, Matthew J. (2017) Genetic predictors of long-term graft function in kidney and pancreas transplant patients. Briefings in Functional Genomics . elw039. ISSN 2041-2649

Simmonds, M. J. (2015) Utilizing genetic variation to predict and extend long-term kidney transplant function. Transplantation, 99 (10). pp. 2038-2048. ISSN 0041-1337

Simmonds, Matthew J. (2013) GWAS in autoimmune thyroid disease: redefining our understanding of pathogenesis. Nature Reviews Endocrinology, 9 (5). pp. 277-287. ISSN 1759-5029

Simmonds, Matthew J. and Gough, Stephen C. L. (2011) The search for the genetic contribution to autoimmune thyroid disease: The never ending story? Briefings in Functional Genomics, 10 (2). pp. 77-90. ISSN 2041-2649

Zeitlin, A. and Simmonds, M. J. and Gough, S. C. (2008) Genetic developments in autoimmune thyroid disease: an evolutionary process. Clinical Endocrinology, 68 (5). pp. 671-682. ISSN 0300-0664

Gough, S .C. L. and Simmonds, Matthew J. (2007) The HLA region and autoimmune disease: associations and mechanisms of action. Current Genomics, 8 (7). pp. 453-465. ISSN 1389-2029

Simmonds, Matthew and Gough, S. C. L. (2005) Genetic insights into disease mechanisms of autoimmunity. British Medical Bulletin, 71 (1). pp. 93-113. ISSN 0007-1420

Simmonds, M. J. and Gough, S. C. L. (2004) Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond. Clinical and Experimental Immunology, 136 (1). pp. 1-10. ISSN 0009-9104

Book Section

Hamilton, Alexander and Gough, Stephen C. L. and Simmonds, Matthew J. (2013) Genetics of Graves’ disease. In: eLS - Encyclopedia of Life Sciences. Wiley. ISBN 9780470015902

Simmonds, Matthew J. and Gough, Stephen C. L. (2011) Endocrine autoimmunity. In: Oxford Textbook of Endocrinology and Diabetes (Second edition). Oxford Textbook series . Oxford University Press, Oxford, pp. 34-44. ISBN 9780199235292

Simmonds, Matthew J. (2011) Evaluating the role of B cells in autoimmune disease: more than just initiators of disease? In: Advances in Medicine and Biology. Nova Science Publishers, pp. 151-176. ISBN 9781613243596