Items where Creator is "Squires, Paul"

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Number of items: 118.

2021

Potter, Joe, Price, Gareth, Cliff, Chelsy L, Green, Colin R, Squires, Paul and Hills, Claire (2021) Collagen I Modifies Connexin‐43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1‐Evoked Renal Tubular Epithelial Cells. International Journal of Molecular Sciences, 22 (7). p. 3644. ISSN 1422-0067

Squires, Paul, Price, Gareth, Mouritzen, Ulrik, Potter, Joe, Williams, Bethany and Hills, Claire (2021) Danegaptide Prevents TGFβ1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney. International Journal of Molecular Sciences, 22 (2809). ISSN 1422-0067

Potter, Joe, Price, Gareth, Cliff, Chelsy, Williams, Bethany, Hills, Claire and Squires, Paul (2021) Carboxyfluorescein Dye Uptake to Measure Connexin-mediated Hemichannel Activity in Cultured Cells. Manual. Bio-Protocol, Bio-Protocol.

2020

Price, G, Chadjichristos, CE, Kavvadas, P, Tang, SCW, Yiu, WH, Green, CR, Potter, JA, Siamantouras, E, Squires, P and Hills, C (2020) Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease. Cell Communication and Signaling, 18 (1). p. 79. ISSN 1478-811X

Potter, Joe, Price, Gareth, Cliff, Chelsy L, Williams, Bethany M, Hills, Claire and Squires, Paul (2020) Inhibition of intern A2B1 negates collagen-1 induced changes in connexion-mediated hemichannel activity in an in vitro model of diabetic nephropathy. In: Diabetes UK AGM, Online.

Price, Gareth, Potter, Joe, Williams, Bethany M, Cliff, Chelsy L, Squires, Paul and Hills, Claire (2020) A role for connexin-43 hemichannel-mediated adenosine triphosphate triphosphate (ATP) release in inflammation of the diabetic proximal tubule. In: Diabetes UK AGM, Online.

Price, Gareth, Potter, Joe, Williams, Bethany M., Cliff, Chelsy L., Squires, Paul and Hills, Claire (2020) Connexin mediated cell communication in the kidney, a potential therapeutic target for future intervention of diabetic kidney disease? Experimental Physiology, 105 (2). pp. 219-229. ISSN 0958-0670

Siamantouras, Eleftherios, Hills, Claire, Liu, Kuo-Kang and Squires, Paul (2020) Examining Cell-Cell Interactions in the Kidney Using AFM Single-Cell Force Spectroscopy. In: Diabetic Nephropathy. Methods in Molecular Biology, 2067 . Humana Press, Humana, New York, NY, pp. 189-201. ISBN 978-1-4939-9840-1, 978-1-4939-9841-8

Siamantouras, Eleftherios, Hills, Claire E., Liu, Kuo-Kang and Squires, Paul E. (2020) Chapter 14: Examining cell-cell interactions in the kidney using AFM single-cell force spectroscopy. In: Diabetic Nephropathy Methods & Protocols. Methods in Molecular Biology Series, 2067 . Springer Science+Business Media, LLC, part of Springer Nature. ISBN 978-1-4939-9840-1

Price, Gareth, Potter, Joe, Williams, Bethany, Cliff, Chelsy, Wall, Mark, Hills, Claire and Squires, Paul (2020) Examining Local Cell-to-Cell Signalling in the Kidney Using ATP Biosensing. In: Methods in Molecular Biology. Springer, New York. ISBN UNSPECIFIED

2019

Siamantouras, Eleftherios, Price, Gareth, Potter, Joe, Hills, Claire and Squires, Paul (2019) Purinergic receptor (P2X7) activation reduces cell–cell adhesion between tubular epithelial cells of the proximal kidney. Nanomedicine: Nanotechnology, Biology and Medicine, 22 . ISSN 1549-9634

Squires, Paul, Siamantouras, Eleftherios, Potter, Joe, Price, Gareth and Hills, Claire (2019) ATP reduces functional cell-to-cell tethering between renal tubular epithelial cells. In: Physiology 2019 (The Physiological Society), 08/07/19-to-10/07/19, Aberdeen.

Price, Gareth, Siamantouras, Eleftherios, Potter, Joe, Squires, Paul and Hills, Claire (2019) Purinergic receptor (P2X7) activation contributes to disassembly of adherens & tight junctions in tubular epithelial cells of the diabetic kidney. In: EASD 2019, 17/09/2019 - 20/09/2019, Barcelona.

Potter, Joe, Price, Gareth, Hills, Claire and Squires, Paul (2019) A role for Collagen I in regulating Connexin-43 mediated hemichannel activity in the proximal region of the diabetic kidney. In: EASD 2019, 17/09/2019 - 20/09/2019, Barcelona.

2018

Hills, C. E., Price, G. W., Wall, M. J., Kauffman, T. J., Tang, S. C., Yiu, W. H. and Squires, Paul (2018) Transforming Growth Factor Beta 1 drives a switch in connexin mediated cell-to-cell communication in tubular cells of the diabetic kidney. Cellular Physiology and Biochemistry, 45 (6). pp. 2369-2388. ISSN 1015-8987

Firth, Katrina, Price, Gareth, Fletcher, Michelle, Squires, Paul and Hills, Claire (2018) Transforming growth factor beta 1 initiates activation of the NLRP3 inflammasome in human derived proximal tubule kidney cells. In: Diabetes UK AGM, 14/03/2018 - 16/03/2018, London.

Siamantouras, Eleftherios, Liu, Lidong, Squires, Paul and Hills, Claire (2018) Understanding the biophysics of diabetic nephropathy: modelling TGFβ1 evoked changes in viscoelasticity of epithelial cells of the proximal tubule. In: Diabetes UK AGM, 14/03/2018 - 16/03/2018, London.

Price, Gareth, Potter, Joe, Squires, Paul and Hills, Claire (2018) A role for ATP in renal fibrosis as a downstream mediator of TGF-β1-evoked changes in hemichannel activity. In: Diabetes UK AGM, 14/03/2018 - 16/03/2018, London.

2017

Hills, Claire, Price, Gareth, Yiu, Stella, Tang, Sydney C and Squires, Paul (2017) A ROLE FOR CONNEXIN MEDIATED CELL COMMUNICATION IN FIBROSIS OF TUBULAR EPITHELIAL CELLS IN THE DIABETIC KIDNEY. In: EASD 2017, Sept 2017, Lisbon.

Price, Gareth, Kaufman, TJ, Wall, MJ, Squires, Paul and Hills, Claire (2017) Transforming growth factor and intercellular communication in tubular epithelial cells: a role in diabetic nephropathy. In: Diabetes UK AGM, 08/03/2017 - 10/03/2019, Manchester.

Squires, Paul, Price, Gareth, Wall, Mark J, Kaufman, Tim J and Hills, Claire (2017) The effect of transforming growth factor beta1 on cell-cell coupling and cell-to-cell communication in tubular epithelial cells of the diabetic kidney. In: European Association for the Study of Diabetes, Sept 2017, Lisbon.

Hills, Claire, Price, Gareth and Squires, Paul (2017) A role for ATP in tubular fibrosis in the diabetic kidney. In: Diabetes AGM, 08/03/2017 - 10/03/2017, Manchester.

Hills, Claire, Price, Gareth, Wall, MJ, Yiu, SW, Tang, S and Squires, Paul (2017) A role for connexin mediated cell communication in fibrosis of tubular epithelial cells in the diabetic kidney. In: European Association for the Study of Diabetes, Sept 2017, Lisbon.

2016

Siamantouras, Eleftherios, Hills, Claire E., Squires, Paul and Liu, Kuo-Kang (2016) Quantifying cellular mechanics and adhesion in renal tubular injury using single cell force spectroscopy. Nanomedicine: Nanotechnology, Biology, and Medicine, 12 (4). pp. 1013-1021. ISSN 1549-9634

Hills, Claire, Price, Gareth and Squires, Paul (2016) Connexins and gap-junction mediated intercellular communication in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

Squires, Paul, Price, Gareth and Hills, Claire (2016) Connexins, hemi-channels and ATP release in the diabetic kidney. In: Society for Endocrinology BES 2016, 07/11/2016 - 09/11/2016, Brighton.

Price, Gareth, Squires, Paul and Hills, Claire (2016) How do cells of the diabetic kidney talk to each other? In: Rose trees Trust PhD Symposium, 21/09/2016, The Blizard Institute, Queen Mary University of London.

2015

Siamantouras, Eleftherios, Hills, Claire E., Squires, Paul E. and Liu, Kuo-Kang (2015) Nanomechanical investigation of soft biological cell adhesion using atomic force microscopy. Cellular and Molecular Bioengineering, 8 (1). pp. 22-31. ISSN 1865-5025

Hills, Claire E., Price, Gareth W. and Squires, Paul E. (2015) Mind the gap: connexins and cell–cell communication in the diabetic kidney. Diabetologia, 58 (2). pp. 233-241. ISSN 0012-186X

Hills, Claire and Squires, Paul (2015) Glucose-evoked changes in Transforming Growth Factor Beta1 modulate cell-substrate binding in human proximal tubule derived epithelial cells. In: Diabetes UK AGM, 11/03/2015 - 13/03/2015, Liverpool.

Siamantouras, Eleftherios, Liu, K-K, Hills, Claire and Squires, Paul (2015) Investigating changes in cell-to-cell adhesion during early proximal tubular injury induced by Transforming Growth Factor-beta in diabetic nephropathy. In: Diabetes UK AGM, 11/03/2015 - 13/03/2015, Liverpool.

Price, Gareth, Squires, Paul and Hills, Claire (2015) Transforming Growth Factor Beta 1 alters purinergic signalling and increases ATP release from epithelial cells derived from the human proximal tubule. In: Diabetes UK AGM, 11/03/2015 - 13/03/2015, Liverpool.

2014

Squires, Paul E., Jones, Peter M., Younis, Mustafa Y. G. and Hills, Claire E. (2014) The calcium-sensing receptor and β-cell function. Vitamins and Hormones, 95 . pp. 249-267. ISSN 0083-6729

Siamantouras, Eleftherios, Hills, Claire E., Younis, Mustafa Y. G., Squires, Paul and Liu, Kuo-Kang (2014) Quantitative investigation of calcimimetic R568 on beta-cell adhesion and mechanics using AFM single-cell force spectroscopy. FEBS Letters, 588 (7). pp. 1178-1183. ISSN 0014-5793

Price, Gareth, Liu, K-K, Squires, Paul and Hills, Claire (2014) Glucose-evoked transforming growth factor reduces connexin and purinergic signalling in proximal tubule-derived epithelial cells. In: Diabetes UK AGM, 05/03/2014 - 07/03/2014, Liverpool.

Siamantouras, Eleftherios, Liu, K-K, Hills, Claire and Squires, Paul (2014) Quantitative investigation of calcium-sensing receptor activation on beta-cell adhesion and mechanics. In: Diabetes UK AGM, 05/03/2014 - 07/03/2014, Liverpool.

Hills, Claire, Kerr, M, Wall, MJ and Squires, Paul (2014) Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells. In: Diabetes UK AGM, 05/03/2014 - 07/03/2014, Liverpool.

2013

Hills, Claire E., Kerr, Michael I., Wall, Mark J. and Squires, Paul E. (2013) Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells. Cellular Physiology and Biochemistry, 32 (5). pp. 1200-1212. ISSN 1015-8987

Hills, Claire E., Jin, Tianrong, Siamantouras, Eleftherios, Liu, Issac K.-K., Jefferson, Kieran P. and Squires, Paul E. (2013) 'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells: modulation of the adherens junction complex by ketamine. PLoS ONE, 8 (8). e71819. ISSN 1932-6203

Liu, Kuo-Kang, Siamantouras, Eleftherios, Squires, Paul and Hills, Claire (2013) Investigating viscoelastic effects on cell adhesion using Atomic Force Microscopy. In: 50th Mechanics and Physics of Biological Cells' symposium, Society of Engineering Science, 28-31 Jul 2013, Rhode Island, USA.

Tym, Amy Elizabeth, Jin, Tianrong, Rabbani, Naila, Rossmeisl, Martin, Kopecky, Jan, Squires, Paul E. and Thornalley, Paul (2013) Dicarbonyl stress and beta-cell dysfunction. In: Glyoxalase Centennial : 100 Years of Glyoxalase Research and Emergence of Dicarbonyl Stress, 27-29 November 2013, University of Warwick, UK.

2012

Hills, Claire E., Bland, Rosemary and Squires, Paul E. (2012) Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy. Experimental Diabetes Research, 2012 . pp. 1-9. ISSN 1687-5214

Hills, C. E., Siamantouras, E., Smith, S. W., Cockwell, P., Liu, K.-K. and Squires, P. E. (2012) TGFβ modulates cell-to-cell communication in early epithelial-to-mesenchymal transition. Diabetologia, 55 (3). pp. 812-824. ISSN 0012-186X

Yang, G. K., Squires, Paul E., Tian, Faming, Kieffer, T. J., Kwok, Y. N. and Dale, Nicholas (2012) Glucose decreases extracellular adenosine levels in isolated mouse and rat pancreatic islets. Islets, 4 (1). pp. 64-70. ISSN 1938-2014

Hills, C. E., Younis, M. Y.G., Bennett, J., Siamantouras, E., Liu, K.-K. and Squires, P. E. (2012) Calcium-sensing receptor activation increases cell-cell adhesion and ß-cell function. Cellular Physiology and Biochemistry, 30 (3). pp. 575-586. ISSN 1015-8987

2011

Hills, Claire E. and Squires, Paul E. (2011) The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy. Cytokine & Growth Factor Reviews, 22 (3). pp. 131-139. ISSN 1359-6101

2010

Stratton, Rebecca C., Squires, Paul E. and Green, Anne K. (2010) 17β-estradiol elevates cGMP and, via plasma membrane recruitment of protein kinase GIa, stimulates Ca2+ efflux from rat hepatocytes. Journal of Biological Chemistry, 28 (35). pp. 27201-27212. ISSN 0021-9258

Hills, C. E., Brunskill, N. J. and Squires, P. E. (2010) C-Peptide as a therapeutic tool in diabetic nephropathy. American Journal of Nephrology, 31 (5). pp. 389-397. ISSN 0250-8095

Hills, Claire E. and Squires, Paul E. (2010) TGF-β1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy. American Journal of Nephrology, 31 (1). pp. 68-74. ISSN 0250-8095

2009

Hills, C. E., Bland, R., Bennett, J., Ronco, P. M. and Squires, P. E. (2009) TGF-beta 1 mediates glucose-evoked up-regulation of connexin-43 cell-to-cell communication in HCD-cells. Cellular Physiology and Biochemistry, 24 (3-4). pp. 177-186. ISSN 1015-8987

Hills, Claire E., Bland, Rosemary and Squires, Paul E. (2009) SGK1 in the kidney: disrupted sodium transport in diabetes and beyond. Asia-Pacific Journal of Endocrinology, 1 (1). pp. 27-34. ISSN 2041-7993

2008

Kitsou-Mylona, Isidora, Burns, Christopher, Squires, Paul, Persaud, Shanta and Jones, Peter (2008) A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of langerhans. Cellular Physiology and Biochemistry, 22 (5-6). pp. 557-566. ISSN 1015-8987

Hills, Claire E., Squires, Paul E. and Bland, Rosemary (2008) Serum and glucocorticoid regulated kinase and disturbed renal sodium transport in diabetes. Journal of Endocrinology, 19 (3). pp. 343-349. ISSN 0022-0795

Hodgkin, M. N., Hills, C. E. and Squires, P. E. (2008) The calcium-sensing receptor and insulin secretion: a role outside systemic control 15 years on. Journal of Endocrinology, 199 (1). pp. 1-4. ISSN 0022-0795

Squires, Paul E., Hills, Claire E., Ronco, Pierre M. and Bland, Rosemary (2008) Functional expression of TRPV4 in human collecting duct (HCD) cells: a role in diabetic nephropathy. In: 43rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Sep 18-21, 2007, Amsterdam, Netherlands.

Holden, Neil S., Squires, Paul E., Kaur, Manminder, Bland, Rosemary, Jones, Carol E. and Newton, R. (Robert) (2008) Phorbol ester-stimulated NF-kappa B-dependent transcription : roles for isoforms of novel protein kinase C. Cellular Signalling, 20 (7). pp. 1338-1348. ISSN 0898-6568

Stratton, Rebecca C., Squires, Paul E. and Green, Anne K. (2008) ANP stimulates hepatocyte Ca2+ efflux via plasma membrane recruitment of PKGIα. Biochemical and Biophysical Research Communications, 36 (4). pp. 965-970. ISSN 0006-291X

Ramraeheya, Reshma D., Muller, Danu S., Squires, Paul E., Brereten, Helen, Sugden, David, Huang, Guo Cai, Amiel, Stephanie, Jones, Peter M. and Persaud, Shanta J. (2008) Function and expression of melatonin receptors on human pancreatic islets. Journal of Pineal Research, 44 (3). pp. 273-279. ISSN 0742-3098

2007

Green, Anne K., Stratton, Rebecca C., Squires, Paul E. and Simpson, Alec W. M. (2007) Atrial natriuretic peptide attenuates elevations in Ca2+ and protects hepatocytes by stimulating net plasma membrane Ca2+ efflux. Journal of Biological Chemistry, 28 (47). pp. 34542-34554. ISSN 0021-9258

Rogers, Gareth J., Hodgkin, Matthew N. and Squires, Paul E. (2007) E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet. Cellular Physiology and Biochemistry, 20 (6). pp. 987-994. ISSN 1015-8987

Jones, Peter M., Kitsou-Mylona, Isidora, Gray, Elizabeth, Squires, Paul E. and Persaud, Shanta J. (2007) Expression and function of the extracellular calcium-sensing receptor in pancreatic beta-cells. Archives of physiology and biochemistry, 113 (3). pp. 98-103. ISSN 1381-3455

Hodgkin, Matthew N., Rogers, Gareth J. and Squires, Paul E. (2007) Colocalization between beta-catenin and insulin suggests a novel role for the adherens junction in beta-cell function. Pancreas, 34 (1). pp. 170-171. ISSN 0885-3177

2006

Hills, Claire E., Bland, Rosemary, Wheelans, Dianne C., Bennett, Jeanette, Ronco, Pierre M. and Squires, Paul E. (2006) Glucose-evoked alterations in connexin43-mediated cell-to-cell communication in human collecting duct: a possible role in diabetic nephropathy. AJP: Renal Physiology, 291 (5). F1045-F1051. ISSN 1931-857x

Gray, Elizabeth, Muller, Dany, Squires, Paul E., Asare-Anane, Henry, Huang, Guo-Cai, Amiel, Stephanie, Persaud, Shanta J. and Jones, Peter M. (2006) Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases. Journal of Endocrinology, 190 (3). pp. 703-710. ISSN 0022-0795

Hills, Claire E., Bland, Rosemary, Ronco, P. M. and Squires, Paul E. (2006) Deranged transcriptional regulation of SGK and ENaC: a link between hyperglycaemia and diabetic nephropathy. In: 42nd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), 14-17 Sep 2006, Copenhagen, Denmark.

Squires, P. E., Rogers, G. J. and Hodgkin, M. N. (2006) E-cadherin-mediated cell adhesion: a role in islet architecture, cell-to-cell coupling and insulin secretion? In: 42nd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), 14-17 Sep 2006, Copenhagen, Denmark.

Hills, Claire E., Bland, Rosemary, Bennett, Jeanette, Ronco, Pierre M. and Squires, Paul E. (2006) High glucose up-regulates ENaC and SGK1 expression in HCD-cells. Cellular Physiology and Biochemistry, 18 (6). pp. 337-346. ISSN 1015-8987

Bland, R., Hills, Claire E., Ronco, P. M., Bennett, J. and Squires, Paul E. (2006) High glucose regulates SGK1 and alpha-ENAC expression in a human cortical collecting duct cell line. In: 197th Meeting of the Society for Endocrinology, 6-7 Novemnber 2006, London, UK.

2005

Squires, Paul E., Churamani, D., Pararajasingam, R., Persaud, S. J. and Jones, P. M. (2005) Similarities of K+ ATP channel expression and Ca 2+ changes in pancreatic β-cells and hypothalamic neurons. Pancreas, 30 (3). pp. 227-232. ISSN 0885-3177

Milne, Helen M., Burns, Chris J., Squires, Paul E., Evans, Nicholas D., Pickup, John, Jones, Peter M. and Persaud, Shanta J. (2005) Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A2. Diabetes, 54 (1). pp. 116-124. ISSN 0012-1797

Al-Majed, H. T., Squires, Paul E., Persaud, S. J., Huang, G.-C. C., Amiel, S., Whitehouse, B. J. and Jones, P. M. (2005) Effect of 17[beta]-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans. Pancreas, 30 (4). pp. 307-313. ISSN 0885-3177

2004

Squires, Paul, Hills, C. E., Rogers, G. J., Garland, P., Farley, S. R. and Morgan, N. G. (2004) The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic β-cells. European Journal of Pharmacology, 501 (1-3). pp. 31-39. ISSN 0014-2999

Bland, R., Markovic, D., Hills, C. E., Hughes, S. V., Chan, S. L. F., Squires, Paul E. and Hewison, M. (2004) Expression of 25-hydroxyvitamin D3-1α-hydroxylase in pancreatic islets. Journal of Steroid Biochemistry and Molecular Biology, 89-90 . pp. 121-125. ISSN 0960-0760

Squires, Paul E., Gray, E., Huang, G. C., Amiel, S. A., Persaud, S. J. and Jones, P. M. (2004) Function of the calcium-sensing receptor in insulin-secreting MIN6 cells and human islets of Langerhans. In: 23rd Joint Meeting of the British Endocrine Societies with the European Federation of Endocrine Societies, 22-24 March 2004, Brighton, UK.

Hills, Claire E., Wheelans, D. C., Ronco, P. M., Bland, R. and Squires, Paul E. (2004) Mechano-receptors and cell-to-cell communication in the human collecting duct: functional involvement of TRPV4 and connexin-43. In: 23rd Joint Meeting of the British Endocrine Societies with the European Federation of Endocrine Societies, 22-24 March 2004, Brighton, UK.

2003

Morgan, N. G., Cooper, E. J., Squires, Paul E., Hills, C. E., Parker, C. A. and Hudson, A. L. (2003) Comparative effects of efaroxan and β-carbolines on the secretory activity of rodent and human β-cells. Annals of the New York Academy of Sciences, 1009 . pp. 167-174. ISSN 0077-8923

Persaud, S. J., Jones, P. M., Roderigo-Milne, H. M., Buchan, A. M. J. and Squires, Paul E. (2003) Calcium-dependent translocation of cytosolic phospholipase A2 in pancreatic β-cells. Biochemical and Biophysical Research Communications, 300 (4). pp. 889-893. ISSN 0006-291X

2002

Squires, Paul E. and Buchan, Alison M. J. (2002) The role of amino acids and calcium in the regulation of human gastrin cell function. In: Gut-brain peptides in the new millennium: a tribute to John Walsh by his collaborators. Cure Foundation, pp. 39-44. ISBN 9780972105408

Hauge-Evans, A. C., Squires, Paul E., Belin, V. D., Roderigo-Milne, H., Ramracheya, R. D., Persaud, S. J. and Jones, P. M. (2002) Role of adenine nucleotides in insulin secretion from MIN6 pseudoislets. Molecular and Cellular Endocrinology, 191 (2). pp. 167-176. ISSN 0303-7207

Squires, Paul E., Persaud, S. J., Hauge-Evans, A. C., Gray, E., Ratcliff, H. and Jones, P. M. (2002) Co-ordinated Ca2+-signalling within pancreatic islets: does β-cell entrainment require a secreted messenger. Cell Calcium, 31 (5). pp. 209-219. ISSN 0143-4160

Whitehouse, B. J., Gyles, S. L., Squires, Paul, Sayed, S. B., Burns, C. J., Persaud, S. J. and Jones, P. M. (2002) Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cell: studies with inhibitors of phosphoprotein phosphatases. Journal of Endocrinology, 172 (3). pp. 583-593. ISSN 0022-0795

Persaud, S. J., Roderigo-Milne, H. M., Squires, Paul E., Sugden, D., Wheeler-Jones, C. P. D., Marsh, P. J., Belin, V. D., Luther, M. J. and Jones, P. M. (2002) A key role for β-cell cytosolic phospholipase A2 in the maintenance of insulin stores but not in the initiation of insulin secretion. Diabetes, 51 (1). pp. 98-104. ISSN 0012-1797

2001

Harris, T. E., Squires, Paul E., Michael, A. E., Bernal, A. L. and Abayasekara, D. Robert (2001) Human granulosa-lutein cells express functional EP1 and EP2 prostaglandin receptors. Biochemical and Biophysical Research Communications, 285 (5). pp. 1089-1094. ISSN 0006-291X

Buchan, Alison M. J., Squires, Paul E., Ring, Mark and Meloche, R. Mark (2001) Mechanism of action of the calcium-sensing receptor in human antral gastrin cells. Gastroenterology, 120 (5). pp. 1128-1139. ISSN 0016-5085

Belin, V. D., Squires, Paul E., Jones, P. M. and Persaud, S. J. (2001) Arachidonic acid and insulin release from human islets of Langerhans. In: 192nd Meeting of the Society for Endocrinology, 3-4 December 2001, London, UK.

2000

Squires, Paul E., Persaud, S. J., Jones, P. M. and Buchan, A. M. J. (2000) The extracellular calcium-sensing receptor in PHHI beta cells: does reduced auto-inhibitory input contribute to hypersecretion of insulin? Diabetologia, 43 (8). pp. 1078-1080. ISSN 0012-186X

Squires, Paul E. (2000) Non-Ca2+-homeostatic functions of the extracellular Ca2+-sensing receptor (CaR) in endocrine tissues. Journal of Endocrinology, 165 (2). pp. 173-177. ISSN 0022-0795

Squires, Paul E., Hauge-Evans, A. C., Persaud, S. J. and Jones, P. M. (2000) Synchronization of Ca2+-signals within insulin-secreting pseudoislets: effects of gap-junctional uncouplers. Cell Calcium, 27 (5). pp. 287-296. ISSN 0143-4160

Harris, T. E., Persaud, S. J., Squires, Paul E. and Jones, P. M. (2000) Depolarizing stimuli reduce Ca2+/calmodulin-dependent protein kinase II activity in islets of Langerhans. Biochemical and Biophysical Research Communications, 270 (3). pp. 1119-1123. ISSN 0006-291X

Squires, Paul E., Harris, T. E., Persaud, S. J., Curtis, S. B., Buchan, A. M. J. and Jones, P. M. (2000) The extracellular calcium-sensing receptor on human β-cells negatively modulates insulin secretion. Diabetes, 49 (3). pp. 409-417. ISSN 0012-1797

Burns, C. J., Squires, Paul and Persaud, S. J. (2000) Signaling through the p38 and p42/44 mitogen-activated families of protein kinases in pancreatic β-cell proliferation. Biochemical and Biophysical Research Communications, 268 (2). pp. 541-546. ISSN 0006-291X

1999

Hauge-Evans, A. C., Squires, Paul E., Persaud, S. J. and Jones, P. M. (1999) Pancreatic β-cell-to-β-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca 2+ and insulin secretory responses of MIN6 pseudoislets. Diabetes, 48 (7). pp. 1402-1408. ISSN 0012-1797

Squires, Paul E., Meloche, R. M. and Buchan, A. M. J. (1999) Bombesin-evoked gastrin release and calcium signaling in human antral G cells in culture. American Journal of Physiology - Gastrointestinal and Liver Physiology, 276 (1 39-1). G227-G237. ISSN 0193-1857

1997

Ray, J. M., Squires, Paul, Meloche, R. M., Nelson, D. W., Snutch, T. P. and Buchan, A. M. J. (1997) L-type calcium channels regulate gastrin release from human antral G cells. American Journal of Physiology - Gastrointestinal and Liver Physiology, 273 (2). G281-G288. ISSN 0193-1857

Ray, J. M., Squires, Paul E., Curtis, S. B., Meloche, M. R. and Buchan, A. M. J. (1997) Expression of the calcium-sensing receptor on human antral gastrin cells in culture. Journal of Clinical Investigation, 99 (10). pp. 2328-2333. ISSN 0021-9738

Squires, Paul E., Lee, P. S. N., Ho Yuen, B., Leung, P. C. K. and Buchen, A. M. J. (1997) Mechanisms involved in ATP-evoked Ca2+ oscillations in isolated human granulosa-luteal cells. Cell Calcium, 21 (5). pp. 365-374. ISSN 0143-4160

Squires, Paul E., James, R. F. L., London, N. J. M. and Dunne, M. J. (1997) Characterization of purinergic receptor-evoked increases in intracellular Ca2+ transients in isolated human and rodent insulin-secreting cells. Advances in Experimental Medicine and Biology, 426 . pp. 173-179. ISSN 0065-2598

Koop, I., Squires, Paul E., Meloche, R. M. and Buchan, A. M. J. (1997) Effect of cholinergic agonists on gastrin release from primary cultures of human antral G cells. Gastroenterology, 112 (2). pp. 357-363. ISSN 0016-5085

1996

Lee, P. S. N., Squires, Paul, Buchan, A. M. J., Yuen, B. H. and Leung, P. C. K. (1996) P 2-purinoreceptor evoked changes in intracellular calcium oscillations in single isolated human granulosa-lutein cells. Endocrinology, 137 (9). pp. 3756-3761. ISSN 0013-7227

Shepherd, R. M., Hashmi, M. N., Kane, C., Squires, Paul and Dunne, M. J. (1996) Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: Implications for stimulus-response coupling of insulin release. British Journal of Pharmacology, 119 (5). pp. 911-916. ISSN 0007-1188

Lindley, K. J., Dunne, M. J., Kane, C., Shepherd, R. M., Squires, Paul, James, R. F. L., Johnson, P. R. V., Eckhardt, S., Wakeling, E., Dattani, M., Milla, P. J. and Aynsley-Green, A. (1996) Ionic control of β cell function in nesidioblastosis. A possible therapeutic role for calcium channel blockade. Archives of Disease in Childhood, 74 (3 SUPP). pp. 373-378. ISSN 0003-9888

Kane, C., Shepherd, R. M., Squires, Paul, Johnson, P. R. V., James, R. F. L., Milla, P. J., Aynsley-Green, A., Lindley, K. J. and Dunne, M. J. (1996) Loss of functional K(ATP) channels in pancreatic β-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nature Medicine, 2 (12). pp. 1344-1347. ISSN 1078-8956

Dunne, M. J., Jaggar, J. H., Harding, E. A., Kane, C. and Squires, Paul E. (1996) Potassium channels in pancreatic beta-cells: modulation, pharmacology and their role in the regulation of insulin secretion. In: Potassium channels and their modulators: from synthesis to clinical experience. The Taylor & Francis series in pharmaceutical sciences . CRC Press/Taylor & Francis, pp. 369-405. ISBN 9780748405572

Squires, Paul E. (1996) Regulation of intracellular Ca2+ in response to muscarinic and glutamate receptor agonists during the differentiation of NTERA2 human embryonal carcinoma cells into neurons. European Journal of Neuroscience, 8 (4). pp. 783-793. ISSN 0953-816X

1995

Dunne, M. J., Harding, E. A., Jaggar, J. H., Ayton, B. J. and Squires, Paul (1995) Endogenous and chemical activators of ATP-regulated potassium channels in insulin secreting cells: possible mechanisms and physiological significance. In: Frontiers of insulin secretion and pancreatic B-cell research. Smith-Gordon, London. ISBN 9781854631046

Dunne, M. J., Jaggar, J. H., Harding, E. A. and Squires, Paul (1995) Protein kinase C and modulation of ion channel activity in insulin-secreting cells. In: Frontiers of insulin secretion and pancreatic B-cell research. Smith-Gordon, London. ISBN 9781854631046

Dunne, Mark J., Harding, Elizabeth A., Jaggar, Jonathan H., Squires, Paul E., Liang, Rixin, Kane, Charlotte, James, Roger F. L. and London, Nicholas J. M. (1995) Potassium channels, imidazolines, and insulin-secreting cells. Annals of the New York Academy of Sciences, 763 . pp. 243-261. ISSN 0077-8923

1994

Squires, Paul E., James, R. F. L., London, N. J. M. and Dunne, M. J. (1994) ATP-induced intracellular Ca2+ signals in isolated human insulin-secreting cells. Pflugers Archiv European Journal of Physiology, 427 (1-2). pp. 181-183. ISSN 0031-6768

Harding, E. A., Jaggar, J. H., Squires, Paul E. and Dunne, M. J. (1994) Polymyxin B has multiple blocking actions on the ATP-sensitive potassium channel in insulin-secreting cells. Pflugers Archiv European Journal of Physiology, 426 (1-2). pp. 31-39. ISSN 0031-6768

Squires, Paul E., Amiranoff, Brigitte and Dunne, Mark J. (1994) Intracellular Ca2+ signals in human-derived pancreatic somatostatin-secreting cells (QGP-1N). Pflugers Archiv European Journal of Physiology, 428 (3-4). pp. 275-282. ISSN 0031-6768

Dunne, M. J., Harding, E. A., Jaggar, J. H. and Squires, Paul E. (1994) Ion channels and the molecular control of insulin secretion. Biochemical Society Transactions, 22 (1). pp. 6-12. ISSN 0300-5127

Squires, Paul and Dunne, M. J. (1994) Modulation of cytoplasmic Ca2+ signals in somatostatin-secreting cells (QGP-1N) by glucose. Biochemical Society Transactions, 22 (1). 9S. ISSN 0300-5127

1993

Squires, Paul E. and Dunne, M. J. (1993) Agonist-evoked, repetitive calcium transients in human-derived pancreatic somatostatin-secreting cells (QGP-1N). Biochemical Society Transactions, 21 (4). 403S. ISSN 0300-5127

Jaggar, J. H., Squires, Paul E. and Dunne, M. J. (1993) Effects of 5-hydroxydecanoate on ATP-regulated potassium ion channels in insulin secreting cells. Biochemical Society Transactions, 21 (4). 427S. ISSN 0300-5127

Squires, Paul E. and Dunne, M. J. (1993) Elevation of intracellular calcium signals in single isolated somatostatin-secreting cells derived from a pancreatic endocrine tumour. Biochemical Society Transactions, 21 (4). 404S. ISSN 0300-5127

Rumsey, R. D. E., Squires, Paul and Read, N. W. (1993) In vitro effects of sennoside on contractile activity and fluid flow in the perfused large intestine of the rat. Pharmacology, 47 (SUP 1). pp. 32-39. ISSN 0031-7012

Harding, E. A., Jaggar, J. H., Squires, Paul E. and Dunne, M. J. (1993) Protein kinase C and the modulation of ATP-sensitive potassium channels in insulin-secreting cells. Biochemical Society Transactions, 21 (4). 388S. ISSN 0300-5127

1992

Squires, Paul E., Rumsey, R .D. E., Edwards, C. A. and Read, N. W. (1992) Effect of short-chain fatty acids on contractile activity and fluid flow in rat colon in vitro. American Journal of Physiology - Gastrointestinal and Liver Physiology, 262 (5 25-5). G813-G817. ISSN 0002-9513

This list was generated on Fri Apr 16 08:41:39 2021 BST.