Adverse drug reactions and quality of life in HIV/AIDS patients: Advocacy on valuation and role of pharmacovigilance in developing countries

Ahmed, Syed, Sulaiman, Syed Azhar Syed, Hassali, Mohammad Azmi and Lee, Christopher K.C. (2015) Adverse drug reactions and quality of life in HIV/AIDS patients: Advocacy on valuation and role of pharmacovigilance in developing countries. HIV & AIDS Review, 14 (1). pp. 28-30. ISSN 1730-1270

Full content URL: https://doi.org/10.1016/j.hivar.2014.07.004

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Item Type:Article
Item Status:Live Archive

Abstract

Background
Evolution of ART treatment of HIV/AIDS presents challenges for patients and health-care professionals, and thus measures of quality of life (QOL) is imperative to maximize outcomes. Similar to other chronic illnesses, HIV patients face challenges in adherence to their medications and experience side effects affecting their overall well-being, a primary outcome of HIV/AIDS treatment.
Discussion
Adverse drug reactions (ADRs) are widely accepted as one of the most significant factors affecting the treatment outcomes which often pose negative impact on patients’ quality of life. This becomes more evident in the treatment of chronic illnesses such as HIV & AIDS, where ADRs are often accountable for issues like non-adherence, which may not only affect the patients’ confidence on ARVs but can eventually affect the whole outcome of the treatment. There is no doubt about the effectiveness of interdisciplinary approach in managing chronic illnesses and a greater role of pharmacist is regarded as one of the key factors in optimizing drug treatment and handling issues related to drug therapy. However disparities among developed and developing health care system is posing challenges in handling medication related issues in developing world.
Summary
Indeed, to use medications effectively, we need to understand more precisely the realities of toxicity and the effect of these toxicities on clinical outcomes. Pharmacists are well known for their importance and effectiveness in optimizing medication therapy which in turns impact positively on patients’ quality of life.

Keywords:HIV, AIDS, Health related quality of life, Adverse drug reactions
Subjects:B Subjects allied to Medicine > B200 Pharmacology, Toxicology and Pharmacy
Divisions:College of Science > School of Pharmacy
ID Code:42969
Deposited On:13 Nov 2020 10:58

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