Three-dimensional voltammetry: use of chronoamperometric E-t-i data to achieve second-order advantage

Lemos, Sherlan and Gonzalez-Rodriguez, Jose (2020) Three-dimensional voltammetry: use of chronoamperometric E-t-i data to achieve second-order advantage. Analytica Chimica Acta, 1132 . ISSN 0003-2670

Full content URL: https://doi.org/10.1016/j.aca.2020.07.062

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Three-dimensional voltammetry: use of chronoamperometric E-t-i data to achieve second-order advantage
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Abstract

This work studied the use of three-dimensional voltammetry, particularly potential-time-current (Et-
i) data, on the development of electroanalytical methods. E-t-i data was obtained by taking
chronoamperograms at potentials applied as pulses on a staircase waveform. By using this threeway
kind of data and appropriate calibration algorithms, the possibility of achieving the secondorder
advantage was evaluated in the determination of ferrocyanide in the presence of the
uncalibrated interference hydroquinone as a model system. The determination of acetaminophen
in urine samples, where ascorbic acid and uric acid play the major roles as interferents was also
studied. Parallel factor analysis (PARAFAC) and multivariate curve resolution alternating leastsquares
(MCR-ALS) were the algorithms employed in this work. Both algorithms successfully
achieved the second-order advantage by correctly predicting the concentrations of the validation
synthetic samples. Excellent predictions were obtained in the direct analysis of acetaminophenspiked
urine samples by E-t-i data and MCR-ALS.

Keywords:Chronoamperometry, paracetamol, Multivariate Calibration, Chemometrics, Three-Dimensional Voltammetry
Subjects:F Physical Sciences > F170 Physical Chemistry
F Physical Sciences > F100 Chemistry
F Physical Sciences > F180 Analytical Chemistry
Divisions:College of Science > School of Chemistry
ID Code:42214
Deposited On:09 Sep 2020 15:52

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