Reductions in plasma endocannabinoids following bariatric surgery in morbidly obese females with impaired glucose homeostasis: a non-randomized prospective study

Mallipedhi, A., Min, T., Prior, S. L. , Dunsheath, G., Bracken, R. M., Barry, J. D., Caplin, S., Eyre, N., Morgan, J., Baxter, J. N., O'Sullivan, S. E., Sarmad, S., Barrett, D. A., Bain, S. C., Luzio, S. D. and Stephens, J. W. (2015) Reductions in plasma endocannabinoids following bariatric surgery in morbidly obese females with impaired glucose homeostasis: a non-randomized prospective study. In: British Obesity and Metabolic Surgery Society, 22-23 January 2015, Newcastle UK.

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Reductions in plasma endocannabinoids following bariatric surgery in morbidly obese females with impaired glucose homeostasis: A non-randomized prospective study
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Item Type:Conference or Workshop contribution (Poster)
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Abstract

Reductions in plasma endocannabinoids following bariatric surgery in morbidly obese females with impaired glucose homeostasis: A non-randomized prospective study • Endocannabinoids (ECs) are bioactive lipid mediators − N-arachidonyl ethanolamine (AEA) − N-palmitoyl ethanolamine (PEA) − N-oleoyl ethanolamine (OEA) − related N-acylethanolamine (NAE) derivatives − 2-arachidonyl glycerol (2-AG) • Endocannabinoid system (ECS) plays a critical role in regulation of body weight and may have a role in aetiopathogenesis of Type 2 Diabetes (T2DM) • Elevated circulating levels of AEA and 2-AG in obese people compared to non-obese controls of both genders • Little information available on the effects of extreme weight loss associated with bariatric surgery in relation to the ECS.

Keywords:Endocannabinoids, Bariatric Surgery, glucose homeostasis
Subjects:C Biological Sciences > C730 Metabolic Biochemistry
Divisions:College of Science > School of Chemistry
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ID Code:31325
Deposited On:14 Mar 2018 11:15

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