Cyclic vomiting syndrome is a prevalent and under-recognized condition in the gastroenterology outpatient clinic

Sagar, R. C., Sood, R., Gracie, D. J. , Gold, M. J., To, N., Law, G. R. and Ford, A. C. (2018) Cyclic vomiting syndrome is a prevalent and under-recognized condition in the gastroenterology outpatient clinic. Neurogastroenterology and Motility, 30 (1). e13174. ISSN 1350-1925

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Item Type:Article
Item Status:Live Archive



Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder (FGID) characterized by intermittent episodes of nausea and vomiting. Our aim was to report its prevalence and associated features.

Data concerning demographics, symptoms, and psychiatric comorbidity were collected. Symptoms compatible with CVS were classified as per Rome III criteria. We recorded whether a diagnosis of CVS was considered in patients after negative investigation. We compared demographics and association with other FGIDs in patients with and without CVS.
Key Results

920 of 1002 patients provided data. Of the 920 patients, 112 (12.2%) had symptoms compatible with CVS. Thirteen (11.6%) of these had an organic cause for their symptoms, but 99 patients (88.4%) were deemed to have CVS (prevalence=10.8%). Organic causes for symptoms compatible with CVS included gastroparesis, large hiatus hernia, achalasia, and small bowel obstruction. Only 39.4% of patients with CVS were asked about vomiting symptoms at their initial consultation, and a diagnosis of CVS was considered in only four (4.0%) of the 99 patients. CVS was associated with younger age, tobacco smoking, never having married, psychiatric comorbidity, and presence of symptoms compatible with other FGIDs (P≤.01).
Conclusions and Inferences

Prevalence of CVS in this outpatient gastroenterology adult population was 10.8%. Identified associations included younger age, tobacco smoking, psychiatric comorbidity, and symptoms compatible with other FGIDs. The condition was considered as a possible diagnosis in <5% of patients who met the diagnostic criteria.

Keywords:Epidemiology, Cyclic Vomiting Syndrome
Subjects:G Mathematical and Computer Sciences > G311 Medical Statistics
Divisions:College of Social Science > School of Health & Social Care
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ID Code:29512
Deposited On:11 Nov 2017 17:34

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