Adherence therapy for people with schizophrenia: European multicentre randomised controlled trial

Gray, Richard and Leese, Morven and Bindman, Jonathan and Becker, Thomas and Burti, Lorenzo and David, Anthony and Gournay, Kevin and Kikkert, Martijn and Koeter, Maarten and Puschner, Bernd (2006) Adherence therapy for people with schizophrenia: European multicentre randomised controlled trial. The British journal of psychiatry (189). pp. 508-514. ISSN 1472-1465

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Full text URL: http://dx.doi.org/10.1192/bjp.bp.105.019489

Abstract

Background: There is equivocal evidence of the effectiveness of adherence therapy in improving treatment adherence and clinical outcomes for people with schizophrenia.

Aims: To evaluate the effectiveness of adherence therapy in improving quality of life for people with schizophrenia.

Method: A 52-week, single-blind, multicentre randomised controlled trial of the effectiveness of adherence therapy. Participants were individually randomised to receive eight sessions of adherence therapy or health education. Assessments were undertaken at baseline and at 52-week follow-up.

Results: Adherence therapy was no more effective than health education in improving quality of life.

Conclusions: This effectiveness trial provides evidence for the lack of effect of adherence therapy in people with schizophrenia with recent clinical instability, treated in ordinary clinical settings.

Item Type:Article
Additional Information:Background: There is equivocal evidence of the effectiveness of adherence therapy in improving treatment adherence and clinical outcomes for people with schizophrenia. Aims: To evaluate the effectiveness of adherence therapy in improving quality of life for people with schizophrenia. Method: A 52-week, single-blind, multicentre randomised controlled trial of the effectiveness of adherence therapy. Participants were individually randomised to receive eight sessions of adherence therapy or health education. Assessments were undertaken at baseline and at 52-week follow-up. Results: Adherence therapy was no more effective than health education in improving quality of life. Conclusions: This effectiveness trial provides evidence for the lack of effect of adherence therapy in people with schizophrenia with recent clinical instability, treated in ordinary clinical settings.
Keywords:Adherence therapy, Schizophrenia, Health education
Subjects:A Medicine and Dentistry > A300 Clinical Medicine
Divisions:College of Social Science > School of Health & Social Care
ID Code:888
Deposited By: Jill Partridge
Deposited On:30 Jun 2007
Last Modified:31 Mar 2010 15:00

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